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- References [165]
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- Product number
- 66095-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#66095-1-Ig, RRID:AB_11232208
- Product name
- Lamin B1 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated Lamin B1 antibody (Cat. #66095-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3C10G12
- Vial size
- 150ul
Submitted references METTL3 Regulates Liver Homeostasis, Hepatocyte Ploidy, and Circadian Rhythm-Controlled Gene Expression in Mice.
3-(3-Hydroxyphenyl)propionic acid, a microbial metabolite of quercetin, inhibits monocyte binding to endothelial cells via modulating E-selectin expression.
PARP1 Inhibitor Combined With Oxaliplatin Efficiently Suppresses Oxaliplatin Resistance in Gastric Cancer-Derived Organoids via Homologous Recombination and the Base Excision Repair Pathway.
Arid4b alters cell cycle and cell death dynamics during mouse embryonic stem cell differentiation.
Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1.
Protective Effect of Jiang Tang Xiao Ke Granules against Skeletal Muscle IR via Activation of the AMPK/SIRT1/PGC-1α Signaling Pathway.
GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy.
Ailanthus Altissima-derived Ailanthone enhances Gastric Cancer Cell Apoptosis by Inducing the Repression of Base Excision Repair by Downregulating p23 Expression.
Bardoxolone-Methyl Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in vitro and Alleviates Osteoarthritis in vivo.
Transcription Coactivator BCL3 Acts as a Potential Regulator of Lipid Metabolism Through the Effects on Inflammation.
PARK7 Protects Against Chronic Kidney Injury and Renal Fibrosis by Inducing SOD2 to Reduce Oxidative Stress.
Angelica Polysaccharide Antagonizes 5-FU-Induced Oxidative Stress Injury to Reduce Apoptosis in the Liver Through Nrf2 Pathway.
HIV-1 requires capsid remodelling at the nuclear pore for nuclear entry and integration.
MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-κB signaling.
Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing.
Protective Effects and Mechanisms of Procyanidins on Parkinson's Disease In Vivo and In Vitro.
Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt.
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Tumour suppressor TET2 safeguards enhancers from aberrant DNA methylation and epigenetic reprogramming in ERα-positive breast cancer cells.
The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 accelerates AOM/DSS induced-tumor initiation.
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
ZFP91 disturbs metabolic fitness and antitumor activity of tumor-infiltrating T cells.
Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct ligation rats by promoting YAP degradation.
Novel WEE2 compound heterozygous mutations identified in patients with fertilization failure or poor fertilization.
ATRX proximal protein associations boast roles beyond histone deposition.
DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma.
SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Methionine and leucine induce ARID1A degradation to promote mTOR expression and milk synthesis in mammary epithelial cells.
KMT2D deficiency disturbs the proliferation and cell cycle activity of dental epithelial cell line (LS8) partially via Wnt signaling.
Temporal proteomics reveal specific cell cycle oncoprotein downregulation by p97/VCP inhibition.
Axon-enriched lincRNA ALAE is required for axon elongation via regulation of local mRNA translation.
TET2 Inhibits PD-L1 Gene Expression in Breast Cancer Cells through Histone Deacetylation.
The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
Psoralidin, a major component of Psoraleae Fructus, induces inflammasome activation and idiosyncratic liver injury.
Sirtuin 1 ameliorates defenestration in hepatic sinusoidal endothelial cells during liver fibrosis via inhibiting stress-induced premature senescence.
miR-142-3p reduces the viability of human cervical cancer cells by negatively regulating the cytoplasmic localization of HMGB1.
Epigenetically modulated miR-1224 suppresses the proliferation of HCC through CREB-mediated activation of YAP signaling pathway.
PUMA facilitates EMI1-promoted cytoplasmic Rad51 ubiquitination and inhibits DNA repair in stem and progenitor cells.
Interaction of NEP with G Protein Pathway Suppressor 2 Facilitates Influenza A Virus Replication by Weakening the Inhibition of GPS2 to RNA Synthesis and Ribonucleoprotein Assembly.
ATAD2 interacts with C/EBPβ to promote esophageal squamous cell carcinoma metastasis via TGF-β1/Smad3 signaling.
Inhibitory activity of flavonoids from Ephedrae Herba on hypoxia signaling in PANC-1 cells and the evaluation of their mechanisms.
Molecular Mechanism of Platelet-Derived Growth Factor (PDGF)-BB-Mediated Protection Against MPP+ Toxicity in SH-SY5Y Cells.
GTSE1 promotes SNAIL1 degradation by facilitating its nuclear export in hepatocellular carcin oma cells.
TNFAIP8L2/TIPE2 impairs autolysosome reformation via modulating the RAC1-MTORC1 axis.
Design, synthesis, and neuroprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opened derivatives.
5'-UTR SNP of FGF13 causes translational defect and intellectual disability.
HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity.
Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP.
Spermidine at supraphysiological doses induces oxidative stress and granulosa cell apoptosis in mouse ovaries.
Fructus Ligustri Lucidi preserves bone quality through induction of canonical Wnt/β-catenin signaling pathway in ovariectomized rats.
The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling.
Identification of STXBP6-IRF1 positive feedback loop in regulation of PD-L1 in cancer.
Regulatory role of DEPTOR‑mediated cellular autophagy and mitochondrial reactive oxygen species in angiogenesis in multiple myeloma.
Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair.
Abnormal nitration and S-sulfhydration modification of Sp1-CSE-H2S pathway trap the progress of hyperhomocysteinemia into a vicious cycle.
Ataxia-telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma.
Ginsenoside Rb1 alleviates liver injury induced by 3-chloro-1,2-propanediol by stimulating autophagic flux.
Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis.
Tangeretin maintains antioxidant activity by reducing CUL3 mediated NRF2 ubiquitination.
BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate.
The missing linker between SUN5 and PMFBP1 in sperm head-tail coupling apparatus.
Cigarette smoke-inactivated SIRT1 promotes autophagy-dependent senescence of alveolar epithelial type 2 cells to induce pulmonary fibrosis.
POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation.
Discovering the Mechanisms of Wikstroelide E as a Potential HIV-Latency-Reversing Agent by Transcriptome Profiling.
Seco-type β-Apocarotenoid Generated by β-Carotene Oxidation Exerts Anti-inflammatory Effects against Activated Macrophages.
Deletion of LBR N-terminal domains recapitulates Pelger-Huet anomaly phenotypes in mouse without disrupting X chromosome inactivation.
Farnesoid X receptor via Notch1 directs asymmetric cell division of Sox9+ cells to prevent the development of liver cancer in a mouse model.
Identification of Beilschmiedia tsangii Root Extract as a Liver Cancer Cell-Normal Keratinocyte Dual-Selective NRF2 Regulator.
Deficiency of CD147 Attenuated Non-alcoholic Steatohepatitis Progression in an NLRP3-Dependent Manner.
β-Actin facilitates etoposide-induced p53 nuclear import.
Tanshinone IIA Protects against Acute Pancreatitis in Mice by Inhibiting Oxidative Stress via the Nrf2/ROS Pathway.
Baicalin Ameliorates Cognitive Impairment and Protects Microglia from LPS-Induced Neuroinflammation via the SIRT1/HMGB1 Pathway.
Metformin Ameliorates Gestational Diabetes Mellitus-Induced Endothelial Dysfunction via Downregulation of p65 and Upregulation of Nrf2.
SREBP1 silencing inhibits the proliferation and motility of human esophageal squamous carcinoma cells via the Wnt/β-catenin signaling pathway.
Malic Enzyme 1 Is Associated with Tumor Budding in Oral Squamous Cell Carcinomas.
Stachydrine hydrochloride suppresses phenylephrine-induced pathological cardiac hypertrophy by inhibiting the calcineurin/nuclear factor of activated T-cell signalling pathway.
Paclitaxel exposure downregulates miR-522 expression and its downregulation induces paclitaxel resistance in ovarian cancer cells.
Evaluation of cancer-derived myocardial impairments using a mouse model.
OGDHL silencing promotes hepatocellular carcinoma by reprogramming glutamine metabolism.
Kynurenine produced by indoleamine 2,3-dioxygenase 2 exacerbates acute liver injury by carbon tetrachloride in mice.
Preclinical Efficacy and Involvement of AKT, mTOR, and ERK Kinases in the Mechanism of Sulforaphane against Endometrial Cancer.
Cucurbitacin B inhibits gastric cancer progression by suppressing STAT3 activity.
23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9.
Quantitative proteomics of synaptosome S-nitrosylation in Alzheimer's disease.
Polymorphisms in Human APOBEC3H Differentially Regulate Ubiquitination and Antiviral Activity.
Polychlorinated biphenyl quinone induces hepatocytes iron overload through up-regulating hepcidin expression.
Expression Levels of SMAD Specific E3 Ubiquitin Protein Ligase 2 (Smurf2) and its Interacting Partners Show Region-specific Alterations During Brain Aging.
CD147 promotes collective invasion through cathepsin B in hepatocellular carcinoma.
Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function.
Baicalein Alleviates Liver Oxidative Stress and Apoptosis Induced by High-Level Glucose through the Activation of the PERK/Nrf2 Signaling Pathway.
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABAA receptors.
Oncogenic role of TYRO3 receptor tyrosine kinase in the progression of pancreatic cancer.
Ribosome 18S m6A Methyltransferase METTL5 Promotes Translation Initiation and Breast Cancer Cell Growth.
Tet2 regulates Barx2 expression in undifferentiated and early differentiated mouse embryonic stem cells.
The vulnerability of motor and frontal cortex-dependent behaviors in mice expressing ALS-linked mutation in TDP-43.
BPTES inhibits anthrax lethal toxin-induced inflammatory response.
Nuclear envelope rupture and NET formation is driven by PKCα-mediated lamin B disassembly.
Effects of peptidoglycan on the development of steatohepatitis.
OTUD1 Negatively Regulates Type I IFN Induction by Disrupting Noncanonical Ubiquitination of IRF3.
CACYBP Enhances Cytoplasmic Retention of P27Kip1 to Promote Hepatocellular Carcinoma Progression in the Absence of RNF41 Mediated Degradation.
Deficiency of emerin contributes differently to the pathogenesis of skeletal and cardiac muscles in LmnaH222P/H222P mutant mice.
Nigericin Promotes NLRP3-Independent Bacterial Killing in Macrophages.
Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins.
Probiotic effect on Helicobacter pylori attachment and inhibition of inflammation in human gastric epithelial cells.
CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity.
ACLY facilitates colon cancer cell metastasis by CTNNB1.
The Nuclear Matrix Protein SAFA Surveils Viral RNA and Facilitates Immunity by Activating Antiviral Enhancers and Super-enhancers.
Arp2/3-Branched Actin Maintains an Active Pool of GTP-RhoA and Controls RhoA Abundance.
USP11 acts as a histone deubiquitinase functioning in chromatin reorganization during DNA repair.
The GRA15 protein from Toxoplasma gondii enhances host defense responses by activating the interferon stimulator STING.
The phosphorylation of Tudor-SN mediated by JNK is involved in the regulation of milk protein synthesis induced by prolactin in BMECs.
Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques.
Inactivation of Cyclic AMP Response Element Transcription Caused by Constitutive p38 Activation Is Mediated by Hyperphosphorylation-Dependent CRTC2 Nucleocytoplasmic Transport.
S-1-Propenylcysteine augments BACH1 degradation and heme oxygenase 1 expression in a nitric oxide-dependent manner in endothelial cells.
Multi-omic Analyses Reveal Minimal Impact of the CRISPR-Cas9 Nuclease on Cultured Human Cells.
Aucubin inhibited lipid accumulation and oxidative stress via Nrf2/HO-1 and AMPK signalling pathways.
NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ.
Atractylodin ameliorates lipopolysaccharide and d-galactosamine-induced acute liver failure via the suppression of inflammation and oxidative stress.
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
Rosmarinic acid protects mice from lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting MAPKs/NF-κB and activating Nrf2/HO-1 signaling pathways.
The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope.
SUMOylation is required for PIPK1γ-driven keratinocyte migration and growth.
Tryptophan Metabolism Activates Aryl Hydrocarbon Receptor-Mediated Pathway To Promote HIV-1 Infection and Reactivation.
Structural Basis for a Species-Specific Determinant of an SIV Vif Protein toward Hominid APOBEC3G Antagonism.
Fibrinopeptide A induces C-reactive protein expression through the ROS-ERK1/2/p38-NF-κB signal pathway in the human umbilical vascular endothelial cells.
Directed self-assembly of herbal small molecules into sustained release hydrogels for treating neural inflammation.
Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation.
Effect of cytoglobin overexpression on extracellular matrix component synthesis in human tenon fibroblasts.
Asiatic Acid (AA) Sensitizes Multidrug-Resistant Human Lung Adenocarcinoma A549/DDP Cells to Cisplatin (DDP) via Downregulation of P-Glycoprotein (MDR1) and Its Targets.
NLRP12 Promotes Mouse Neutrophil Differentiation through Regulation of Non-canonical NF-κB and MAPKERK1/2 Signaling.
Interferon Gamma Inhibits CXCL8-Induced Proliferation and Migration of Pancreatic Cancer BxPC-3 Cell Line via a RhoGDI2/Rac1/NF-κB Signaling Pathway.
TET2 inhibits tumorigenesis of breast cancer cells by regulating caspase-4.
Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.
Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal.
Dioscin inhibits stem-cell-like properties and tumor growth of osteosarcoma through Akt/GSK3/β-catenin signaling pathway.
Decreased expression of SFRP2 promotes development of the pituitary corticotroph adenoma by upregulating Wnt signaling.
Protective Effects of Sulforaphane on Cognitive Impairments and AD-like Lesions in Diabetic Mice are Associated with the Upregulation of Nrf2 Transcription Activity.
Basolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress.
The E3 ubiquitin ligase MuRF2 attenuates LPS-induced macrophage activation by inhibiting production of inflammatory cytokines and migration.
Radix Salviae miltiorrhizae improves bone microstructure and strength through Wnt/β-catenin and osteoprotegerin/receptor activator for nuclear factor-κB ligand/cathepsin K signaling in ovariectomized rats.
Twist1 Enhances Hypoxia Induced Radioresistance in Cervical Cancer Cells by Promoting Nuclear EGFR Localization.
KIAA1199 promotes migration and invasion by Wnt/β-catenin pathway and MMPs mediated EMT progression and serves as a poor prognosis marker in gastric cancer.
MTEP impedes the neuronal polarization and the activity of the Akt-NF-κB pathway in rat hippocampal neurons.
Quercetin protects against atherosclerosis by inhibiting dendritic cell activation.
Proteome profiling of s-nitrosylated synaptosomal proteins by isobaric mass tags.
Thyroid stimulating hormone increases hepatic gluconeogenesis via CRTC2.
Nuclear accumulation of symplekin promotes cellular proliferation and dedifferentiation in an ERK1/2-dependent manner.
Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy.
HTLV-1 Tax upregulates early growth response protein 1 through nuclear factor-κB signaling.
The DEAD-Box RNA Helicase DDX3 Interacts with NF-κB Subunit p65 and Suppresses p65-Mediated Transcription.
The SUMO2/3 specific E3 ligase ZNF451-1 regulates PML stability.
HMGB1 Enhances Drug Resistance and Promotes In Vivo Tumor Growth of Lung Cancer Cells.
The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1.
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
The long noncoding RNA ASNR regulates degradation of Bcl-2 mRNA through its interaction with AUF1.
Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity.
DDX21 translocates from nucleus to cytoplasm and stimulates the innate immune response due to dengue virus infection.
Interleukin-33 is released in spinal cord and suppresses experimental autoimmune encephalomyelitis in mice.
Simulated microgravity promotes monocyte adhesion to rat aortic endothelium via nuclear factor-κB activation.
Astrocyte elevated gene-1 promotes progression of cervical squamous cell carcinoma by inducing epithelial-mesenchymal transition via Wnt signaling.
Rho GDIalpha Modulates Rabbit Trophoblast Stem Cell Survival and Migration.
Hepatitis B virus hijacks CTHRC1 to evade host immunity and maintain replication.
Activin A induces growth arrest through a SMAD- dependent pathway in hepatic progenitor cells.
Notch1 signaling antagonizes transforming growth factor-β pathway and induces apoptosis in rabbit trophoblast stem cells.
Barajas JM, Lin CH, Sun HL, Alencastro F, Zhu AC, Aljuhani M, Navari L, Yilmaz SA, Yu L, Corps K, He C, Duncan AW, Ghoshal K
The American journal of pathology 2022 Jan;192(1):56-71
The American journal of pathology 2022 Jan;192(1):56-71
3-(3-Hydroxyphenyl)propionic acid, a microbial metabolite of quercetin, inhibits monocyte binding to endothelial cells via modulating E-selectin expression.
Feng J, Ge C, Li W, Li R
Fitoterapia 2022 Jan;156:105071
Fitoterapia 2022 Jan;156:105071
PARP1 Inhibitor Combined With Oxaliplatin Efficiently Suppresses Oxaliplatin Resistance in Gastric Cancer-Derived Organoids via Homologous Recombination and the Base Excision Repair Pathway.
Li H, Wang C, Lan L, Wu W, Evans I, Ruiz EJ, Yan L, Zhou Z, Oliveira JM, Reis RL, Hu Z, Chen W, Behrens A, He Y, Zhang C
Frontiers in cell and developmental biology 2021;9:719192
Frontiers in cell and developmental biology 2021;9:719192
Arid4b alters cell cycle and cell death dynamics during mouse embryonic stem cell differentiation.
GÜven G, Terzİ ÇİzmecİoĞlu N
Turkish journal of biology = Turk biyoloji dergisi 2021;45(1):56-64
Turkish journal of biology = Turk biyoloji dergisi 2021;45(1):56-64
Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1.
Hu X, Li M, Zhang C, Pang S
International journal of endocrinology 2021;2021:8867218
International journal of endocrinology 2021;2021:8867218
Protective Effect of Jiang Tang Xiao Ke Granules against Skeletal Muscle IR via Activation of the AMPK/SIRT1/PGC-1α Signaling Pathway.
Bai Y, Zuo J, Fang X, Ma R, Tian T, Mo F, Mu Q, Zhang Y, Yu N, Bao X, Zhang D, Gao S, Zhao D
Oxidative medicine and cellular longevity 2021;2021:5566053
Oxidative medicine and cellular longevity 2021;2021:5566053
GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy.
Guo W, Li W, Su Y, Liu S, Kan X, Ran X, Cao Y, Fu S, Liu J
International journal of biological sciences 2021;17(15):4271-4284
International journal of biological sciences 2021;17(15):4271-4284
Ailanthus Altissima-derived Ailanthone enhances Gastric Cancer Cell Apoptosis by Inducing the Repression of Base Excision Repair by Downregulating p23 Expression.
Wang CM, Li HF, Wang XK, Li WG, Su Q, Xiao X, Hao TF, Chen W, Zhang YW, Zhang HY, Wu W, Hu ZR, Zhao GY, Huo MY, He YL, Zhang CH
International journal of biological sciences 2021;17(11):2811-2825
International journal of biological sciences 2021;17(11):2811-2825
Bardoxolone-Methyl Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in vitro and Alleviates Osteoarthritis in vivo.
Pang Z, Jiang Z, Zhu R, Song C, Tang H, Cao L, Guo C
Drug design, development and therapy 2021;15:3735-3747
Drug design, development and therapy 2021;15:3735-3747
Transcription Coactivator BCL3 Acts as a Potential Regulator of Lipid Metabolism Through the Effects on Inflammation.
Zhang S, Gao J, Liu S, Yu L, Zhang W, Liang Y, Wang H
Journal of inflammation research 2021;14:4915-4926
Journal of inflammation research 2021;14:4915-4926
PARK7 Protects Against Chronic Kidney Injury and Renal Fibrosis by Inducing SOD2 to Reduce Oxidative Stress.
Yin L, Li H, Liu Z, Wu W, Cai J, Tang C, Dong Z
Frontiers in immunology 2021;12:690697
Frontiers in immunology 2021;12:690697
Angelica Polysaccharide Antagonizes 5-FU-Induced Oxidative Stress Injury to Reduce Apoptosis in the Liver Through Nrf2 Pathway.
Zeng D, Wang Y, Chen Y, Li D, Li G, Xiao H, Hou J, Wang Z, Hu L, Wang L, Li J
Frontiers in oncology 2021;11:720620
Frontiers in oncology 2021;11:720620
HIV-1 requires capsid remodelling at the nuclear pore for nuclear entry and integration.
Guedán A, Donaldson CD, Caroe ER, Cosnefroy O, Taylor IA, Bishop KN
PLoS pathogens 2021 Sep;17(9):e1009484
PLoS pathogens 2021 Sep;17(9):e1009484
MEST promotes lung cancer invasion and metastasis by interacting with VCP to activate NF-κB signaling.
Wang Y, Zhang J, Li YJ, Yu NN, Liu WT, Liang JZ, Xu WW, Sun ZH, Li B, He QY
Journal of experimental & clinical cancer research : CR 2021 Sep 24;40(1):301
Journal of experimental & clinical cancer research : CR 2021 Sep 24;40(1):301
Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing.
Zhang Q, Zhang J, Ye J, Li X, Liu H, Ma X, Wang C, He K, Zhang W, Yuan J, Zhao Y, Xu H, Liu Q
Molecular neurodegeneration 2021 Sep 22;16(1):66
Molecular neurodegeneration 2021 Sep 22;16(1):66
Protective Effects and Mechanisms of Procyanidins on Parkinson's Disease In Vivo and In Vitro.
Chen J, Chen Y, Zheng Y, Zhao J, Yu H, Zhu J, Li D
Molecules (Basel, Switzerland) 2021 Sep 13;26(18)
Molecules (Basel, Switzerland) 2021 Sep 13;26(18)
Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt.
Liu C, Ma L, Wang Y, Zhao J, Chen P, Chen X, Wang Y, Hu Y, Liu Y, Jia X, Yang Z, Yin X, Wu J, Wu S, Zheng H, Ma X, Sun X, He Y, Lin L, Fu Y, Liao K, Zhou X, Jiang S, Fu G, Tang J, Han W, Chen XL, Fan W, Hong Y, Han J, Huang X, Li BA, Xiao N, Xiao C, Fu G, Liu WH
Science advances 2021 Oct 8;7(41):eabg6262
Science advances 2021 Oct 8;7(41):eabg6262
Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy.
Han Y, Xiong S, Zhao H, Yang S, Yang M, Zhu X, Jiang N, Xiong X, Gao P, Wei L, Xiao Y, Sun L
Cell death & disease 2021 Oct 30;12(11):1031
Cell death & disease 2021 Oct 30;12(11):1031
Tumour suppressor TET2 safeguards enhancers from aberrant DNA methylation and epigenetic reprogramming in ERα-positive breast cancer cells.
Lyu R, Zhu X, Shen Y, Xiong L, Liu L, Liu H, Wu F, Argueta C, Tan L
Epigenetics 2021 Oct 30;:1-15
Epigenetics 2021 Oct 30;:1-15
The overexpression of Tipe2 in CRC cells suppresses survival while endogenous Tipe2 accelerates AOM/DSS induced-tumor initiation.
Li Y, Zhang N, Ma C, Xu W, Jin G, Zheng Y, Zhang L, Liu B, Gao C, Liu S
Cell death & disease 2021 Oct 26;12(11):1001
Cell death & disease 2021 Oct 26;12(11):1001
Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota.
Zhao Y, Liu X, Zheng Y, Liu W, Ding C
Scientific reports 2021 Oct 18;11(1):20558
Scientific reports 2021 Oct 18;11(1):20558
ZFP91 disturbs metabolic fitness and antitumor activity of tumor-infiltrating T cells.
Wang F, Zhang Y, Yu X, Teng XL, Ding R, Hu Z, Wang A, Wang Z, Ye Y, Zou Q
The Journal of clinical investigation 2021 Oct 1;131(19)
The Journal of clinical investigation 2021 Oct 1;131(19)
Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct ligation rats by promoting YAP degradation.
Lu ZN, Niu WX, Zhang N, Ge MX, Bao YY, Ren Y, Guo XL, He HW
Acta pharmacologica Sinica 2021 Nov;42(11):1808-1820
Acta pharmacologica Sinica 2021 Nov;42(11):1808-1820
Novel WEE2 compound heterozygous mutations identified in patients with fertilization failure or poor fertilization.
Jin J, Tong X, Zhang YL, Yang W, Ma Y, Ren P, Zhou F, Zhang S
Journal of assisted reproduction and genetics 2021 Nov;38(11):2861-2869
Journal of assisted reproduction and genetics 2021 Nov;38(11):2861-2869
ATRX proximal protein associations boast roles beyond histone deposition.
Scott WA, Dhanji EZ, Dyakov BJA, Dreseris ES, Asa JS, Grange LJ, Mirceta M, Pearson CE, Stewart GS, Gingras AC, Campos EI
PLoS genetics 2021 Nov;17(11):e1009909
PLoS genetics 2021 Nov;17(11):e1009909
DNMT1-induced miR-378a-3p silencing promotes angiogenesis via the NF-κB signaling pathway by targeting TRAF1 in hepatocellular carcinoma.
Zhu B, Chen JJ, Feng Y, Yang JL, Huang H, Chung WY, Hu YL, Xue WJ
Journal of experimental & clinical cancer research : CR 2021 Nov 8;40(1):352
Journal of experimental & clinical cancer research : CR 2021 Nov 8;40(1):352
SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.
Zhao Y, Mao A, Zhang R, Guan S, Lu J
Environmental toxicology 2021 Nov 29;
Environmental toxicology 2021 Nov 29;
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Li M, Rao X, Cui Y, Zhang L, Li X, Wang B, Zheng Y, Teng L, Zhou T, Zhuo W
Oncogene 2021 Nov 29;
Oncogene 2021 Nov 29;
Methionine and leucine induce ARID1A degradation to promote mTOR expression and milk synthesis in mammary epithelial cells.
Qi H, Wang L, Zhang M, Wang Z, Gao X, Li M
The Journal of nutritional biochemistry 2021 Nov 27;101:108924
The Journal of nutritional biochemistry 2021 Nov 27;101:108924
KMT2D deficiency disturbs the proliferation and cell cycle activity of dental epithelial cell line (LS8) partially via Wnt signaling.
Pang L, Tian H, Gao X, Wang W, Wang X, Zhang Z
Bioscience reports 2021 Nov 26;41(11)
Bioscience reports 2021 Nov 26;41(11)
Temporal proteomics reveal specific cell cycle oncoprotein downregulation by p97/VCP inhibition.
Wang F, Li S, Houerbi N, Chou TF
Cell chemical biology 2021 Nov 23;
Cell chemical biology 2021 Nov 23;
Axon-enriched lincRNA ALAE is required for axon elongation via regulation of local mRNA translation.
Wei M, Huang J, Li GW, Jiang B, Cheng H, Liu X, Jiang X, Zhang X, Yang L, Bao L, Wang B
Cell reports 2021 May 4;35(5):109053
Cell reports 2021 May 4;35(5):109053
TET2 Inhibits PD-L1 Gene Expression in Breast Cancer Cells through Histone Deacetylation.
Shen Y, Liu L, Wang M, Xu B, Lyu R, Shi YG, Tan L
Cancers 2021 May 4;13(9)
Cancers 2021 May 4;13(9)
The SUN1-SPDYA interaction plays an essential role in meiosis prophase I.
Chen Y, Wang Y, Chen J, Zuo W, Fan Y, Huang S, Liu Y, Chen G, Li Q, Li J, Wu J, Bian Q, Huang C, Lei M
Nature communications 2021 May 26;12(1):3176
Nature communications 2021 May 26;12(1):3176
Psoralidin, a major component of Psoraleae Fructus, induces inflammasome activation and idiosyncratic liver injury.
Wang Y, Xu G, Wang Z, Li R, Zhan X, Liu H, Qin Q, Li W, Wang X, Zhang M, Tang J, Bai Z, Xiao X
International immunopharmacology 2021 Mar;92:107352
International immunopharmacology 2021 Mar;92:107352
Sirtuin 1 ameliorates defenestration in hepatic sinusoidal endothelial cells during liver fibrosis via inhibiting stress-induced premature senescence.
Luo X, Bai Y, He S, Sun S, Jiang X, Yang Z, Lu D, Wei P, Liang Y, Peng C, Wang Y, Sheng R, Han S, Li X, Zhang B
Cell proliferation 2021 Mar;54(3):e12991
Cell proliferation 2021 Mar;54(3):e12991
miR-142-3p reduces the viability of human cervical cancer cells by negatively regulating the cytoplasmic localization of HMGB1.
Dong H, Song J
Experimental and therapeutic medicine 2021 Mar;21(3):212
Experimental and therapeutic medicine 2021 Mar;21(3):212
Epigenetically modulated miR-1224 suppresses the proliferation of HCC through CREB-mediated activation of YAP signaling pathway.
Yang S, Jiang W, Yang W, Yang C, Yang X, Chen K, Hu Y, Shen G, Lu L, Cheng F, Zhang F, Rao J, Wang X
Molecular therapy. Nucleic acids 2021 Mar 5;23:944-958
Molecular therapy. Nucleic acids 2021 Mar 5;23:944-958
PUMA facilitates EMI1-promoted cytoplasmic Rad51 ubiquitination and inhibits DNA repair in stem and progenitor cells.
Kang JW, Zhan Z, Ji G, Sang Y, Zhou D, Li Y, Feng H, Cheng T
Signal transduction and targeted therapy 2021 Mar 31;6(1):129
Signal transduction and targeted therapy 2021 Mar 31;6(1):129
Interaction of NEP with G Protein Pathway Suppressor 2 Facilitates Influenza A Virus Replication by Weakening the Inhibition of GPS2 to RNA Synthesis and Ribonucleoprotein Assembly.
Gong W, He X, Huang K, Zhang Y, Li C, Yang Y, Zou Z, Jin M
Journal of virology 2021 Mar 3;
Journal of virology 2021 Mar 3;
ATAD2 interacts with C/EBPβ to promote esophageal squamous cell carcinoma metastasis via TGF-β1/Smad3 signaling.
Cao LJ, Zhang YJ, Dong SQ, Li XZ, Tong XT, Chen D, Wu ZY, Zheng XH, Xue WQ, Jia WH, Zhang JB
Journal of experimental & clinical cancer research : CR 2021 Mar 23;40(1):109
Journal of experimental & clinical cancer research : CR 2021 Mar 23;40(1):109
Inhibitory activity of flavonoids from Ephedrae Herba on hypoxia signaling in PANC-1 cells and the evaluation of their mechanisms.
Yahagi H, Yahagi T, Matsumura M, Igarashi K, Yokoyama N, Matsuzaki K
Journal of natural medicines 2021 Jun;75(3):612-622
Journal of natural medicines 2021 Jun;75(3):612-622
Molecular Mechanism of Platelet-Derived Growth Factor (PDGF)-BB-Mediated Protection Against MPP+ Toxicity in SH-SY5Y Cells.
Chen H, Teng Y, Liu Z, Geng F, Chen X, Jiang H, Yang J, Zheng M, Wang Z, Yang L
Journal of molecular neuroscience : MN 2021 Jun;71(6):1131-1143
Journal of molecular neuroscience : MN 2021 Jun;71(6):1131-1143
GTSE1 promotes SNAIL1 degradation by facilitating its nuclear export in hepatocellular carcin oma cells.
Li SS, Chen DM, Chen LB, Wei H, Wang JL, Xiao J, Huang YH, Lian YF
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
TNFAIP8L2/TIPE2 impairs autolysosome reformation via modulating the RAC1-MTORC1 axis.
Li W, Li Y, Guan Y, Du Y, Zhao M, Chen X, Zhu F, Guo C, Jia Y, Li Y, Wang X, Wang X, Shi Y, Wang Q, Li Y, Zhang L
Autophagy 2021 Jun;17(6):1410-1425
Autophagy 2021 Jun;17(6):1410-1425
Design, synthesis, and neuroprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opened derivatives.
Li X, Wang X, Miao L, Guo Y, Yuan R, Tian H
Biochemical and biophysical research communications 2021 Jun 4;556:99-105
Biochemical and biophysical research communications 2021 Jun 4;556:99-105
5'-UTR SNP of FGF13 causes translational defect and intellectual disability.
Pan X, Zhao J, Zhou Z, Chen J, Yang Z, Wu Y, Bai M, Jiao Y, Yang Y, Hu X, Cheng T, Lu Q, Wang B, Li CL, Lu YJ, Diao L, Zhong YQ, Pan J, Zhu J, Xiao HS, Qiu ZL, Li J, Wang Z, Hui J, Bao L, Zhang X
eLife 2021 Jun 29;10
eLife 2021 Jun 29;10
HO-1 nuclear accumulation and interaction with NPM1 protect against stress-induced endothelial senescence independent of its enzymatic activity.
Luo W, Li J, Li Z, Lin T, Zhang L, Yang W, Mai Y, Liu R, Chen M, Dai C, Yang H, Lu J, Li H, Guan G, Huang M, Liu P, Li Z
Cell death & disease 2021 Jul 26;12(8):738
Cell death & disease 2021 Jul 26;12(8):738
Inactivation of the tumor suppressor p53 by long noncoding RNA RMRP.
Chen Y, Hao Q, Wang S, Cao M, Huang Y, Weng X, Wang J, Zhang Z, He X, Lu H, Zhou X
Proceedings of the National Academy of Sciences of the United States of America 2021 Jul 20;118(29)
Proceedings of the National Academy of Sciences of the United States of America 2021 Jul 20;118(29)
Spermidine at supraphysiological doses induces oxidative stress and granulosa cell apoptosis in mouse ovaries.
Jiang D, Jiang Y, Long S, Chen Z, Li Y, Mo G, Bai L, Hao X, Yan Y, Li L, Han C, Hu S, Zhao H, Kang B
Theriogenology 2021 Jul 1;168:25-32
Theriogenology 2021 Jul 1;168:25-32
Fructus Ligustri Lucidi preserves bone quality through induction of canonical Wnt/β-catenin signaling pathway in ovariectomized rats.
Liu H, Guo Y, Zhu R, Wang L, Chen B, Tian Y, Li R, Ma R, Jia Q, Zhang H, Xia B, Li Y, Wang X, Zhu X, Zhang R, Brӧmme D, Gao S, Zhang D, Pei X
Phytotherapy research : PTR 2021 Jan;35(1):424-441
Phytotherapy research : PTR 2021 Jan;35(1):424-441
The mitochondrial protein ERAL1 suppresses RNA virus infection by facilitating RIG-I-like receptor signaling.
Li S, Kuang M, Chen L, Li Y, Liu S, Du H, Cao L, You F
Cell reports 2021 Jan 19;34(3):108631
Cell reports 2021 Jan 19;34(3):108631
Identification of STXBP6-IRF1 positive feedback loop in regulation of PD-L1 in cancer.
Liu Y, Huang Z, Wei Y, Zhang M, Li X, Yang S, Wang H
Cancer immunology, immunotherapy : CII 2021 Feb;70(2):275-287
Cancer immunology, immunotherapy : CII 2021 Feb;70(2):275-287
Regulatory role of DEPTOR‑mediated cellular autophagy and mitochondrial reactive oxygen species in angiogenesis in multiple myeloma.
Wang J, Chen J, Qiu D, Zeng Z
International journal of molecular medicine 2021 Feb;47(2):643-658
International journal of molecular medicine 2021 Feb;47(2):643-658
Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair.
Murray-Nerger LA, Justice JL, Rekapalli P, Hutton JE, Cristea IM
Nucleic acids research 2021 Feb 26;49(4):2044-2064
Nucleic acids research 2021 Feb 26;49(4):2044-2064
Abnormal nitration and S-sulfhydration modification of Sp1-CSE-H2S pathway trap the progress of hyperhomocysteinemia into a vicious cycle.
Luo C, Ji D, Li Y, Cao Y, Zhang S, Yan W, Xue K, Chai J, Wu Y, Liu H, Wang W
Free radical biology & medicine 2021 Feb 20;164:20-33
Free radical biology & medicine 2021 Feb 20;164:20-33
Ataxia-telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma.
Sarkar A, Stellrecht CM, Vangapandu HV, Ayres M, Kaipparettu BA, Park JH, Balakrishnan K, Burks JK, Pandita TK, Hittelman WN, Neelapu SS, Gandhi V
Haematologica 2021 Feb 1;106(2):495-512
Haematologica 2021 Feb 1;106(2):495-512
Ginsenoside Rb1 alleviates liver injury induced by 3-chloro-1,2-propanediol by stimulating autophagic flux.
Lu J, Lu J, Bu X, Li Y, Ge G, Guan S
Journal of food science 2021 Dec;86(12):5503-5515
Journal of food science 2021 Dec;86(12):5503-5515
Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis.
Zou Q, Yang L, Shi R, Qi Y, Zhang X, Qi H
iScience 2021 Dec 17;24(12):103396
iScience 2021 Dec 17;24(12):103396
Tangeretin maintains antioxidant activity by reducing CUL3 mediated NRF2 ubiquitination.
Wang Y, Jin R, Chen J, Cao J, Xiao J, Li X, Sun C
Food chemistry 2021 Dec 15;365:130470
Food chemistry 2021 Dec 15;365:130470
BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate.
Nagy A, Pethő D, Gesztelyi R, Juhász B, Balla G, Szilvássy Z, Balla J, Gáll T
International journal of molecular sciences 2021 Aug 26;22(17)
International journal of molecular sciences 2021 Aug 26;22(17)
The missing linker between SUN5 and PMFBP1 in sperm head-tail coupling apparatus.
Zhang Y, Liu C, Wu B, Li L, Li W, Yuan L
Nature communications 2021 Aug 13;12(1):4926
Nature communications 2021 Aug 13;12(1):4926
Cigarette smoke-inactivated SIRT1 promotes autophagy-dependent senescence of alveolar epithelial type 2 cells to induce pulmonary fibrosis.
Zhang Y, Huang W, Zheng Z, Wang W, Yuan Y, Hong Q, Lin J, Li X, Meng Y
Free radical biology & medicine 2021 Apr;166:116-127
Free radical biology & medicine 2021 Apr;166:116-127
POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation.
Xiao J, Xiong Y, Yang LT, Wang JQ, Zhou ZM, Dong LW, Shi XJ, Zhao X, Luo J, Song BL
Protein & cell 2021 Apr;12(4):279-296
Protein & cell 2021 Apr;12(4):279-296
Discovering the Mechanisms of Wikstroelide E as a Potential HIV-Latency-Reversing Agent by Transcriptome Profiling.
Li SF, Liang X, Wu XK, Gao X, Zhang LW
Journal of natural products 2021 Apr 23;84(4):1022-1033
Journal of natural products 2021 Apr 23;84(4):1022-1033
Seco-type β-Apocarotenoid Generated by β-Carotene Oxidation Exerts Anti-inflammatory Effects against Activated Macrophages.
Takatani N, Beppu F, Yamano Y, Maoka T, Hosokawa M
Journal of oleo science 2021 Apr 2;70(4):549-558
Journal of oleo science 2021 Apr 2;70(4):549-558
Deletion of LBR N-terminal domains recapitulates Pelger-Huet anomaly phenotypes in mouse without disrupting X chromosome inactivation.
Young AN, Perlas E, Ruiz-Blanes N, Hierholzer A, Pomella N, Martin-Martin B, Liverziani A, Jachowicz JW, Giannakouros T, Cerase A
Communications biology 2021 Apr 12;4(1):478
Communications biology 2021 Apr 12;4(1):478
Farnesoid X receptor via Notch1 directs asymmetric cell division of Sox9+ cells to prevent the development of liver cancer in a mouse model.
Chen M, Lu C, Lu H, Zhang J, Qin D, Liu S, Li X, Zhang L
Stem cell research & therapy 2021 Apr 12;12(1):232
Stem cell research & therapy 2021 Apr 12;12(1):232
Identification of Beilschmiedia tsangii Root Extract as a Liver Cancer Cell-Normal Keratinocyte Dual-Selective NRF2 Regulator.
Chen YS, Chang HS, Hsiao HH, Chen YF, Kuo YP, Yen FL, Yen CH
Antioxidants (Basel, Switzerland) 2021 Apr 1;10(4)
Antioxidants (Basel, Switzerland) 2021 Apr 1;10(4)
Deficiency of CD147 Attenuated Non-alcoholic Steatohepatitis Progression in an NLRP3-Dependent Manner.
Zhang T, Li H, Wang K, Xu B, Chen ZN, Bian H
Frontiers in cell and developmental biology 2020;8:784
Frontiers in cell and developmental biology 2020;8:784
β-Actin facilitates etoposide-induced p53 nuclear import.
Qi W, Li J, Pei X, Ke Y, Bu Q, Ni X
Journal of biosciences 2020;45
Journal of biosciences 2020;45
Tanshinone IIA Protects against Acute Pancreatitis in Mice by Inhibiting Oxidative Stress via the Nrf2/ROS Pathway.
Chen W, Yuan C, Lu Y, Zhu Q, Ma X, Xiao W, Gong W, Huang W, Xia Q, Lu G, Li W
Oxidative medicine and cellular longevity 2020;2020:5390482
Oxidative medicine and cellular longevity 2020;2020:5390482
Baicalin Ameliorates Cognitive Impairment and Protects Microglia from LPS-Induced Neuroinflammation via the SIRT1/HMGB1 Pathway.
Li Y, Liu T, Li Y, Han D, Hong J, Yang N, He J, Peng R, Mi X, Kuang C, Zhou Y, Han Y, Shi C, Li Z, Guo X
Oxidative medicine and cellular longevity 2020;2020:4751349
Oxidative medicine and cellular longevity 2020;2020:4751349
Metformin Ameliorates Gestational Diabetes Mellitus-Induced Endothelial Dysfunction via Downregulation of p65 and Upregulation of Nrf2.
Sun CC, Lai YN, Wang WH, Xu XM, Li XQ, Wang H, Zheng JY, Zheng JQ
Frontiers in pharmacology 2020;11:575390
Frontiers in pharmacology 2020;11:575390
SREBP1 silencing inhibits the proliferation and motility of human esophageal squamous carcinoma cells via the Wnt/β-catenin signaling pathway.
Wang J, Ling R, Zhou Y, Gao X, Yang Y, Mao C, Chen D
Oncology letters 2020 Sep;20(3):2855-2869
Oncology letters 2020 Sep;20(3):2855-2869
Malic Enzyme 1 Is Associated with Tumor Budding in Oral Squamous Cell Carcinomas.
Nakashima C, Kirita T, Yamamoto K, Mori S, Luo Y, Sasaki T, Fujii K, Ohmori H, Kawahara I, Mori T, Goto K, Kishi S, Fujiwara-Tani R, Kuniyasu H
International journal of molecular sciences 2020 Sep 28;21(19)
International journal of molecular sciences 2020 Sep 28;21(19)
Stachydrine hydrochloride suppresses phenylephrine-induced pathological cardiac hypertrophy by inhibiting the calcineurin/nuclear factor of activated T-cell signalling pathway.
Zheng J, Tian J, Wang S, Hu P, Wu Q, Shan X, Zhao P, Zhang C, Guo W, Xu M, Chen H, Lu R
European journal of pharmacology 2020 Sep 15;883:173386
European journal of pharmacology 2020 Sep 15;883:173386
Paclitaxel exposure downregulates miR-522 expression and its downregulation induces paclitaxel resistance in ovarian cancer cells.
Miyamoto M, Sawada K, Nakamura K, Yoshimura A, Ishida K, Kobayashi M, Shimizu A, Yamamoto M, Kodama M, Hashimoto K, Kimura T
Scientific reports 2020 Oct 7;10(1):16755
Scientific reports 2020 Oct 7;10(1):16755
Evaluation of cancer-derived myocardial impairments using a mouse model.
Miyagawa Y, Nukaga S, Mori T, Fujiwara-Tani R, Fujii K, Mori S, Goto K, Kishi S, Sasaki T, Nakashima C, Ohmori H, Kawahara I, Luo Y, Kuniyasu H
Oncotarget 2020 Oct 13;11(41):3712-3722
Oncotarget 2020 Oct 13;11(41):3712-3722
OGDHL silencing promotes hepatocellular carcinoma by reprogramming glutamine metabolism.
Dai W, Xu L, Yu X, Zhang G, Guo H, Liu H, Song G, Weng S, Dong L, Zhu J, Liu T, Guo C, Shen X
Journal of hepatology 2020 May;72(5):909-923
Journal of hepatology 2020 May;72(5):909-923
Kynurenine produced by indoleamine 2,3-dioxygenase 2 exacerbates acute liver injury by carbon tetrachloride in mice.
Hoshi M, Osawa Y, Nakamoto K, Morita N, Yamamoto Y, Ando T, Tashita C, Nabeshima T, Saito K
Toxicology 2020 May 30;438:152458
Toxicology 2020 May 30;438:152458
Preclinical Efficacy and Involvement of AKT, mTOR, and ERK Kinases in the Mechanism of Sulforaphane against Endometrial Cancer.
Rai R, Gong Essel K, Mangiaracina Benbrook D, Garland J, Daniel Zhao Y, Chandra V
Cancers 2020 May 18;12(5)
Cancers 2020 May 18;12(5)
Cucurbitacin B inhibits gastric cancer progression by suppressing STAT3 activity.
Xu J, Chen Y, Yang R, Zhou T, Ke W, Si Y, Yang S, Zhang T, Liu X, Zhang L, Xiang K, Guo Y, Liu Y
Archives of biochemistry and biophysics 2020 May 15;684:108314
Archives of biochemistry and biophysics 2020 May 15;684:108314
23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9.
Li HH, Li J, Zhang XJ, Li JM, Xi C, Wang WQ, Lu YL, Xuan LJ
Acta pharmacologica Sinica 2020 Mar;41(3):327-335
Acta pharmacologica Sinica 2020 Mar;41(3):327-335
Quantitative proteomics of synaptosome S-nitrosylation in Alzheimer's disease.
Wijasa TS, Sylvester M, Brocke-Ahmadinejad N, Schwartz S, Santarelli F, Gieselmann V, Klockgether T, Brosseron F, Heneka MT
Journal of neurochemistry 2020 Mar;152(6):710-726
Journal of neurochemistry 2020 Mar;152(6):710-726
Polymorphisms in Human APOBEC3H Differentially Regulate Ubiquitination and Antiviral Activity.
Chesarino NM, Emerman M
Viruses 2020 Mar 30;12(4)
Viruses 2020 Mar 30;12(4)
Polychlorinated biphenyl quinone induces hepatocytes iron overload through up-regulating hepcidin expression.
Liu J, Tan Y, Yang B, Wu Y, Fan B, Zhu S, Song E, Song Y
Environment international 2020 Jun;139:105701
Environment international 2020 Jun;139:105701
Expression Levels of SMAD Specific E3 Ubiquitin Protein Ligase 2 (Smurf2) and its Interacting Partners Show Region-specific Alterations During Brain Aging.
Sasik MUT, Eravsar ETK, Kinali M, Ergul AA, Adams MM
Neuroscience 2020 Jun 1;436:46-73
Neuroscience 2020 Jun 1;436:46-73
CD147 promotes collective invasion through cathepsin B in hepatocellular carcinoma.
Wang SJ, Chao D, Wei W, Nan G, Li JY, Liu FL, Li L, Jiang JL, Cui HY, Chen ZN
Journal of experimental & clinical cancer research : CR 2020 Jul 29;39(1):145
Journal of experimental & clinical cancer research : CR 2020 Jul 29;39(1):145
Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function.
Wang J, Li S, Wang J, Wu F, Chen Y, Zhang H, Guo Y, Lin Y, Li L, Yu X, Liu T, Zhao Y
Aging 2020 Jan 6;12(1):650-671
Aging 2020 Jan 6;12(1):650-671
Baicalein Alleviates Liver Oxidative Stress and Apoptosis Induced by High-Level Glucose through the Activation of the PERK/Nrf2 Signaling Pathway.
Dong Y, Xing Y, Sun J, Sun W, Xu Y, Quan C
Molecules (Basel, Switzerland) 2020 Jan 30;25(3)
Molecules (Basel, Switzerland) 2020 Jan 30;25(3)
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABAA receptors.
Teoh J, Subramanian N, Pero ME, Bartolini F, Amador A, Kanber A, Williams D, Petri S, Yang M, Allen AS, Beal J, Haut SR, Frankel WN
Neurobiology of disease 2020 Feb;134:104632
Neurobiology of disease 2020 Feb;134:104632
Oncogenic role of TYRO3 receptor tyrosine kinase in the progression of pancreatic cancer.
Morimoto M, Horikoshi Y, Nakaso K, Kurashiki T, Kitagawa Y, Hanaki T, Sakamoto T, Honjo S, Umekita Y, Fujiwara Y, Matsura T
Cancer letters 2020 Feb 1;470:149-160
Cancer letters 2020 Feb 1;470:149-160
Ribosome 18S m6A Methyltransferase METTL5 Promotes Translation Initiation and Breast Cancer Cell Growth.
Rong B, Zhang Q, Wan J, Xing S, Dai R, Li Y, Cai J, Xie J, Song Y, Chen J, Zhang L, Yan G, Zhang W, Gao H, Han JJ, Qu Q, Ma H, Tian Y, Lan F
Cell reports 2020 Dec 22;33(12):108544
Cell reports 2020 Dec 22;33(12):108544
Tet2 regulates Barx2 expression in undifferentiated and early differentiated mouse embryonic stem cells.
Qiao Z, Zhang S, Hu T, Lan F, Yu D, Ge G, Li C, Fang S, Chen Q
Biochemical and biophysical research communications 2020 Dec 17;533(4):1212-1218
Biochemical and biophysical research communications 2020 Dec 17;533(4):1212-1218
The vulnerability of motor and frontal cortex-dependent behaviors in mice expressing ALS-linked mutation in TDP-43.
Wong P, Ho WY, Yen YC, Sanford E, Ling SC
Neurobiology of aging 2020 Aug;92:43-60
Neurobiology of aging 2020 Aug;92:43-60
BPTES inhibits anthrax lethal toxin-induced inflammatory response.
Wang J, Yang D, Shen X, Wang J, Liu X, Lin J, Zhong J, Zhao Y, Qi Z
International immunopharmacology 2020 Aug;85:106664
International immunopharmacology 2020 Aug;85:106664
Nuclear envelope rupture and NET formation is driven by PKCα-mediated lamin B disassembly.
Li Y, Li M, Weigel B, Mall M, Werth VP, Liu ML
EMBO reports 2020 Aug 5;21(8):e48779
EMBO reports 2020 Aug 5;21(8):e48779
Effects of peptidoglycan on the development of steatohepatitis.
Jin M, Lai Y, Zhao P, Shen Q, Su W, Yin Y, Zhang W
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Apr;1865(4):158595
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Apr;1865(4):158595
OTUD1 Negatively Regulates Type I IFN Induction by Disrupting Noncanonical Ubiquitination of IRF3.
Zhang Z, Wang D, Wang P, Zhao Y, You F
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 1;204(7):1904-1918
Journal of immunology (Baltimore, Md. : 1950) 2020 Apr 1;204(7):1904-1918
CACYBP Enhances Cytoplasmic Retention of P27Kip1 to Promote Hepatocellular Carcinoma Progression in the Absence of RNF41 Mediated Degradation.
Lian YF, Huang YL, Zhang YJ, Chen DM, Wang JL, Wei H, Bi YH, Jiang ZW, Li P, Chen MS, Huang YH
Theranostics 2019;9(26):8392-8408
Theranostics 2019;9(26):8392-8408
Deficiency of emerin contributes differently to the pathogenesis of skeletal and cardiac muscles in LmnaH222P/H222P mutant mice.
Wada E, Kato M, Yamashita K, Kokuba H, Liang WC, Bonne G, Hayashi YK
PloS one 2019;14(8):e0221512
PloS one 2019;14(8):e0221512
Nigericin Promotes NLRP3-Independent Bacterial Killing in Macrophages.
Armstrong H, Bording-Jorgensen M, Chan R, Wine E
Frontiers in immunology 2019;10:2296
Frontiers in immunology 2019;10:2296
Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins.
Xiao J, Luo J, Hu A, Xiao T, Li M, Kong Z, Jiang L, Zhou Z, Liao Y, Xie C, Chu B, Miao H, Li B, Shi X, Song BL
Science China. Life sciences 2019 Sep;62(9):1117-1135
Science China. Life sciences 2019 Sep;62(9):1117-1135
Probiotic effect on Helicobacter pylori attachment and inhibition of inflammation in human gastric epithelial cells.
Song H, Zhou L, Liu D, Ge L, Li Y
Experimental and therapeutic medicine 2019 Sep;18(3):1551-1562
Experimental and therapeutic medicine 2019 Sep;18(3):1551-1562
CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity.
Sang Y, Li Y, Zhang Y, Alvarez AA, Yu B, Zhang W, Hu B, Cheng SY, Feng H
Nature communications 2019 Sep 5;10(1):4013
Nature communications 2019 Sep 5;10(1):4013
ACLY facilitates colon cancer cell metastasis by CTNNB1.
Wen J, Min X, Shen M, Hua Q, Han Y, Zhao L, Liu L, Huang G, Liu J, Zhao X
Journal of experimental & clinical cancer research : CR 2019 Sep 12;38(1):401
Journal of experimental & clinical cancer research : CR 2019 Sep 12;38(1):401
The Nuclear Matrix Protein SAFA Surveils Viral RNA and Facilitates Immunity by Activating Antiviral Enhancers and Super-enhancers.
Cao L, Liu S, Li Y, Yang G, Luo Y, Li S, Du H, Zhao Y, Wang D, Chen J, Zhang Z, Li M, Ouyang S, Gao X, Sun Y, Wang Z, Yang L, Lin R, Wang P, You F
Cell host & microbe 2019 Sep 11;26(3):369-384.e8
Cell host & microbe 2019 Sep 11;26(3):369-384.e8
Arp2/3-Branched Actin Maintains an Active Pool of GTP-RhoA and Controls RhoA Abundance.
Huang Y, Yi X, Kang C, Wu C
Cells 2019 Oct 16;8(10)
Cells 2019 Oct 16;8(10)
USP11 acts as a histone deubiquitinase functioning in chromatin reorganization during DNA repair.
Ting X, Xia L, Yang J, He L, Si W, Shang Y, Sun L
Nucleic acids research 2019 Oct 10;47(18):9721-9740
Nucleic acids research 2019 Oct 10;47(18):9721-9740
The GRA15 protein from Toxoplasma gondii enhances host defense responses by activating the interferon stimulator STING.
Wang P, Li S, Zhao Y, Zhang B, Li Y, Liu S, Du H, Cao L, Ou M, Ye X, Li P, Gao X, Wang P, Jing C, Shao F, Yang G, You F
The Journal of biological chemistry 2019 Nov 8;294(45):16494-16508
The Journal of biological chemistry 2019 Nov 8;294(45):16494-16508
The phosphorylation of Tudor-SN mediated by JNK is involved in the regulation of milk protein synthesis induced by prolactin in BMECs.
Zhang S, Qi H, Wen XP, Li P, Gao XJ, Ao JX
Journal of cellular physiology 2019 May;234(5):6077-6090
Journal of cellular physiology 2019 May;234(5):6077-6090
Thyrotropin aggravates atherosclerosis by promoting macrophage inflammation in plaques.
Yang C, Lu M, Chen W, He Z, Hou X, Feng M, Zhang H, Bo T, Zhou X, Yu Y, Zhang H, Zhao M, Wang L, Yu C, Gao L, Jiang W, Zhang Q, Zhao J
The Journal of experimental medicine 2019 May 6;216(5):1182-1198
The Journal of experimental medicine 2019 May 6;216(5):1182-1198
Inactivation of Cyclic AMP Response Element Transcription Caused by Constitutive p38 Activation Is Mediated by Hyperphosphorylation-Dependent CRTC2 Nucleocytoplasmic Transport.
Ma H, Liu Z, Zhong CQ, Liu Y, Zhang Z, Liang Y, Li J, Han S, Han J
Molecular and cellular biology 2019 May 1;39(9)
Molecular and cellular biology 2019 May 1;39(9)
S-1-Propenylcysteine augments BACH1 degradation and heme oxygenase 1 expression in a nitric oxide-dependent manner in endothelial cells.
Tsuneyoshi T, Kunimura K, Morihara N
Nitric oxide : biology and chemistry 2019 Mar 1;84:22-29
Nitric oxide : biology and chemistry 2019 Mar 1;84:22-29
Multi-omic Analyses Reveal Minimal Impact of the CRISPR-Cas9 Nuclease on Cultured Human Cells.
Qiang J, Ma Z, Xie X, Shi L, Geng Y, Hu J, Liu R, Liu N, Zhang Y
Journal of proteome research 2019 Mar 1;18(3):1054-1063
Journal of proteome research 2019 Mar 1;18(3):1054-1063
Aucubin inhibited lipid accumulation and oxidative stress via Nrf2/HO-1 and AMPK signalling pathways.
Shen B, Zhao C, Wang Y, Peng Y, Cheng J, Li Z, Wu L, Jin M, Feng H
Journal of cellular and molecular medicine 2019 Jun;23(6):4063-4075
Journal of cellular and molecular medicine 2019 Jun;23(6):4063-4075
NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ.
Luan P, Jian W, Xu X, Kou W, Yu Q, Hu H, Li D, Wang W, Feinberg MW, Zhuang J, Xu Y, Peng W
Nature communications 2019 Jun 28;10(1):2882
Nature communications 2019 Jun 28;10(1):2882
Atractylodin ameliorates lipopolysaccharide and d-galactosamine-induced acute liver failure via the suppression of inflammation and oxidative stress.
Lyu Z, Ji X, Chen G, An B
International immunopharmacology 2019 Jul;72:348-357
International immunopharmacology 2019 Jul;72:348-357
Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation.
Zhong S, Li L, Zhang YL, Zhang L, Lu J, Guo S, Liang N, Ge J, Zhu M, Tao Y, Wu YC, Yin H
The Journal of clinical investigation 2019 Jan 2;129(1):252-267
The Journal of clinical investigation 2019 Jan 2;129(1):252-267
Rosmarinic acid protects mice from lipopolysaccharide/d-galactosamine-induced acute liver injury by inhibiting MAPKs/NF-κB and activating Nrf2/HO-1 signaling pathways.
Li Z, Feng H, Wang Y, Shen B, Tian Y, Wu L, Zhang Q, Jin M, Liu G
International immunopharmacology 2019 Feb;67:465-472
International immunopharmacology 2019 Feb;67:465-472
The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope.
Wang Y, Chen Y, Chen J, Wang L, Nie L, Long J, Chang H, Wu J, Huang C, Lei M
Nature communications 2019 Feb 4;10(1):564
Nature communications 2019 Feb 4;10(1):564
SUMOylation is required for PIPK1γ-driven keratinocyte migration and growth.
Ni W, Li Y, Cai L, Dong C, Fang H, Chen Y, Li H, Yao M, Xiao N
The FEBS journal 2019 Dec;286(23):4709-4720
The FEBS journal 2019 Dec;286(23):4709-4720
Tryptophan Metabolism Activates Aryl Hydrocarbon Receptor-Mediated Pathway To Promote HIV-1 Infection and Reactivation.
Zhou YH, Sun L, Chen J, Sun WW, Ma L, Han Y, Jin X, Zhao QX, Li T, Lu H, Qiu X, Wang JH
mBio 2019 Dec 17;10(6)
mBio 2019 Dec 17;10(6)
Structural Basis for a Species-Specific Determinant of an SIV Vif Protein toward Hominid APOBEC3G Antagonism.
Binning JM, Chesarino NM, Emerman M, Gross JD
Cell host & microbe 2019 Dec 11;26(6):739-747.e4
Cell host & microbe 2019 Dec 11;26(6):739-747.e4
Fibrinopeptide A induces C-reactive protein expression through the ROS-ERK1/2/p38-NF-κB signal pathway in the human umbilical vascular endothelial cells.
Zhao J, Xu SZ, Liu J
Journal of cellular physiology 2019 Aug;234(8):13481-13492
Journal of cellular physiology 2019 Aug;234(8):13481-13492
Directed self-assembly of herbal small molecules into sustained release hydrogels for treating neural inflammation.
Zheng J, Fan R, Wu H, Yao H, Yan Y, Liu J, Ran L, Sun Z, Yi L, Dang L, Gan P, Zheng P, Yang T, Zhang Y, Tang T, Wang Y
Nature communications 2019 Apr 8;10(1):1604
Nature communications 2019 Apr 8;10(1):1604
Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation.
Ben J, Jiang B, Wang D, Liu Q, Zhang Y, Qi Y, Tong X, Chen L, Liu X, Zhang Y, Zhu X, Li X, Zhang H, Bai H, Yang Q, Ma J, Wiemer EAC, Xu Y, Chen Q
Nature communications 2019 Apr 17;10(1):1801
Nature communications 2019 Apr 17;10(1):1801
Effect of cytoglobin overexpression on extracellular matrix component synthesis in human tenon fibroblasts.
Wei H, Lin L, Zhang X, Feng Z, Wang Y, You Y, Wang X, Hou Y
Biological research 2019 Apr 16;52(1):23
Biological research 2019 Apr 16;52(1):23
Asiatic Acid (AA) Sensitizes Multidrug-Resistant Human Lung Adenocarcinoma A549/DDP Cells to Cisplatin (DDP) via Downregulation of P-Glycoprotein (MDR1) and Its Targets.
Cheng Q, Liao M, Hu H, Li H, Wu L
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):279-292
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):279-292
NLRP12 Promotes Mouse Neutrophil Differentiation through Regulation of Non-canonical NF-κB and MAPKERK1/2 Signaling.
Wang Q, Liu F, Zhang M, Zhou P, Xu C, Li Y, Bian L, Liu Y, Yao Y, Wang F, Fang Y, Li D
International journal of biological sciences 2018;14(2):147-155
International journal of biological sciences 2018;14(2):147-155
Interferon Gamma Inhibits CXCL8-Induced Proliferation and Migration of Pancreatic Cancer BxPC-3 Cell Line via a RhoGDI2/Rac1/NF-κB Signaling Pathway.
Zhang M, Ding G, Zhou L, Shen T, Xu X, Zhao T, Jia S, Cao L
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2018 Sep;38(9):413-422
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2018 Sep;38(9):413-422
TET2 inhibits tumorigenesis of breast cancer cells by regulating caspase-4.
Zhu X, Li S
Scientific reports 2018 Nov 1;8(1):16167
Scientific reports 2018 Nov 1;8(1):16167
Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.
Yang JY, Deng XY, Li YS, Ma XC, Feng JX, Yu B, Chen Y, Luo YL, Wang X, Chen ML, Fang ZX, Zheng FX, Li YP, Zhong Q, Kang TB, Song LB, Xu RH, Zeng MS, Chen W, Zhang H, Xie W, Gao S
Nature communications 2018 Mar 21;9(1):1165
Nature communications 2018 Mar 21;9(1):1165
Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal.
Wen J, Lv R, Ma H, Shen H, He C, Wang J, Jiao F, Liu H, Yang P, Tan L, Lan F, Shi YG, He C, Shi Y, Diao J
Molecular cell 2018 Mar 15;69(6):1028-1038.e6
Molecular cell 2018 Mar 15;69(6):1028-1038.e6
Dioscin inhibits stem-cell-like properties and tumor growth of osteosarcoma through Akt/GSK3/β-catenin signaling pathway.
Liu W, Zhao Z, Wang Y, Li W, Su Q, Jia Q, Zhang J, Zhang X, Shen J, Yin J
Cell death & disease 2018 Mar 1;9(3):343
Cell death & disease 2018 Mar 1;9(3):343
Decreased expression of SFRP2 promotes development of the pituitary corticotroph adenoma by upregulating Wnt signaling.
Ren J, Jian F, Jiang H, Sun Y, Pan S, Gu C, Chen X, Wang W, Ning G, Bian L, Sun Q
International journal of oncology 2018 Jun;52(6):1934-1946
International journal of oncology 2018 Jun;52(6):1934-1946
Protective Effects of Sulforaphane on Cognitive Impairments and AD-like Lesions in Diabetic Mice are Associated with the Upregulation of Nrf2 Transcription Activity.
Pu D, Zhao Y, Chen J, Sun Y, Lv A, Zhu S, Luo C, Zhao K, Xiao Q
Neuroscience 2018 Jun 15;381:35-45
Neuroscience 2018 Jun 15;381:35-45
Basolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress.
Lu M, Wu J, Hao ZW, Shang YK, Xu J, Nan G, Li X, Chen ZN, Bian H
Hepatology (Baltimore, Md.) 2018 Jul;68(1):317-332
Hepatology (Baltimore, Md.) 2018 Jul;68(1):317-332
The E3 ubiquitin ligase MuRF2 attenuates LPS-induced macrophage activation by inhibiting production of inflammatory cytokines and migration.
Bian H, Gao S, Zhang D, Zhao Q, Li F, Li X, Sun S, Song S, Li T, Zhu Q, Ren W, Qin C, Qi J
FEBS open bio 2018 Feb;8(2):234-243
FEBS open bio 2018 Feb;8(2):234-243
Radix Salviae miltiorrhizae improves bone microstructure and strength through Wnt/β-catenin and osteoprotegerin/receptor activator for nuclear factor-κB ligand/cathepsin K signaling in ovariectomized rats.
Liu H, Zhu R, Wang L, Liu C, Ma R, Qi B, Chen B, Li L, Guo Y, Shi S, Jia Q, Niu J, Zhao D, Mo F, Gao S, Zhang D
Phytotherapy research : PTR 2018 Dec;32(12):2487-2500
Phytotherapy research : PTR 2018 Dec;32(12):2487-2500
Twist1 Enhances Hypoxia Induced Radioresistance in Cervical Cancer Cells by Promoting Nuclear EGFR Localization.
Xiong H, Nie X, Zou Y, Gong C, Li Y, Wu H, Qiu H, Yang L, Zhuang L, Zhang P, Zhang J, Wang Y, Xiong H
Journal of Cancer 2017;8(3):345-353
Journal of Cancer 2017;8(3):345-353
KIAA1199 promotes migration and invasion by Wnt/β-catenin pathway and MMPs mediated EMT progression and serves as a poor prognosis marker in gastric cancer.
Jia S, Qu T, Wang X, Feng M, Yang Y, Feng X, Ma R, Li W, Hu Y, Feng Y, Ji K, Li Z, Jiang W, Ji J
PloS one 2017;12(4):e0175058
PloS one 2017;12(4):e0175058
MTEP impedes the neuronal polarization and the activity of the Akt-NF-κB pathway in rat hippocampal neurons.
Zhang X, Hu M, Zhang L, An J, Yan W, Zhang Z, Liu J, Lu H, Chen X, Liu Y
Journal of neuroscience research 2017 Sep;95(9):1730-1744
Journal of neuroscience research 2017 Sep;95(9):1730-1744
Quercetin protects against atherosclerosis by inhibiting dendritic cell activation.
Lin W, Wang W, Wang D, Ling W
Molecular nutrition & food research 2017 Sep;61(9)
Molecular nutrition & food research 2017 Sep;61(9)
Proteome profiling of s-nitrosylated synaptosomal proteins by isobaric mass tags.
Wijasa TS, Sylvester M, Brocke-Ahmadinejad N, Kummer MP, Brosseron F, Gieselmann V, Heneka MT
Journal of neuroscience methods 2017 Nov 1;291:95-100
Journal of neuroscience methods 2017 Nov 1;291:95-100
Thyroid stimulating hormone increases hepatic gluconeogenesis via CRTC2.
Li Y, Wang L, Zhou L, Song Y, Ma S, Yu C, Zhao J, Xu C, Gao L
Molecular and cellular endocrinology 2017 May 5;446:70-80
Molecular and cellular endocrinology 2017 May 5;446:70-80
Nuclear accumulation of symplekin promotes cellular proliferation and dedifferentiation in an ERK1/2-dependent manner.
Zhang C, Mao HL, Cao Y
Scientific reports 2017 Jun 19;7(1):3769
Scientific reports 2017 Jun 19;7(1):3769
Cytoplasmic fragment of CD147 generated by regulated intramembrane proteolysis contributes to HCC by promoting autophagy.
Wu B, Cui J, Yang XM, Liu ZY, Song F, Li L, Jiang JL, Chen ZN
Cell death & disease 2017 Jul 13;8(7):e2925
Cell death & disease 2017 Jul 13;8(7):e2925
HTLV-1 Tax upregulates early growth response protein 1 through nuclear factor-κB signaling.
Huang Q, Niu Z, Han J, Liu X, Lv Z, Li H, Yuan L, Li X, Sun S, Wang H, Huang X
Oncotarget 2017 Aug 1;8(31):51123-51133
Oncotarget 2017 Aug 1;8(31):51123-51133
The DEAD-Box RNA Helicase DDX3 Interacts with NF-κB Subunit p65 and Suppresses p65-Mediated Transcription.
Xiang N, He M, Ishaq M, Gao Y, Song F, Guo L, Ma L, Sun G, Liu D, Guo D, Chen Y
PloS one 2016;11(10):e0164471
PloS one 2016;11(10):e0164471
The SUMO2/3 specific E3 ligase ZNF451-1 regulates PML stability.
Koidl S, Eisenhardt N, Fatouros C, Droescher M, Chaugule VK, Pichler A
The international journal of biochemistry & cell biology 2016 Oct;79:478-487
The international journal of biochemistry & cell biology 2016 Oct;79:478-487
HMGB1 Enhances Drug Resistance and Promotes In Vivo Tumor Growth of Lung Cancer Cells.
Zheng H, Chen JN, Yu X, Jiang P, Yuan L, Shen HS, Zhao LH, Chen PF, Yang M
DNA and cell biology 2016 Oct;35(10):622-627
DNA and cell biology 2016 Oct;35(10):622-627
The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1.
He M, Wang M, Huang Y, Peng W, Zheng Z, Xia N, Xu J, Tian D
Scientific reports 2016 Jun 8;6:27597
Scientific reports 2016 Jun 8;6:27597
Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation.
Nie D, Zhang D, Dai J, Zhang M, Zhao X, Xu W, Chen Z, Wang L, Wang Z, Qiao Z
Biology of reproduction 2016 Feb;94(2):31
Biology of reproduction 2016 Feb;94(2):31
The long noncoding RNA ASNR regulates degradation of Bcl-2 mRNA through its interaction with AUF1.
Chen J, Liu L, Wei G, Wu W, Luo H, Yuan J, Luo J, Chen R
Scientific reports 2016 Aug 31;6:32189
Scientific reports 2016 Aug 31;6:32189
Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity.
Wu J, Guo W, Lin SZ, Wang ZJ, Kan JT, Chen SY, Zhu YZ
Cell death & disease 2016 Aug 18;7(8):e2339
Cell death & disease 2016 Aug 18;7(8):e2339
DDX21 translocates from nucleus to cytoplasm and stimulates the innate immune response due to dengue virus infection.
Dong Y, Ye W, Yang J, Han P, Wang Y, Ye C, Weng D, Zhang F, Xu Z, Lei Y
Biochemical and biophysical research communications 2016 Apr 29;473(2):648-53
Biochemical and biophysical research communications 2016 Apr 29;473(2):648-53
Interleukin-33 is released in spinal cord and suppresses experimental autoimmune encephalomyelitis in mice.
Chen H, Sun Y, Lai L, Wu H, Xiao Y, Ming B, Gao M, Zou H, Xiong P, Xu Y, Tan Z, Gong F, Zheng F
Neuroscience 2015 Nov 12;308:157-68
Neuroscience 2015 Nov 12;308:157-68
Simulated microgravity promotes monocyte adhesion to rat aortic endothelium via nuclear factor-κB activation.
Liu H, Wang ZC, Bai YG, Cai Y, Yu JW, Zhang HJ, Bao JX, Ren XL, Xie MJ, Ma J
Clinical and experimental pharmacology & physiology 2015 May;42(5):510-9
Clinical and experimental pharmacology & physiology 2015 May;42(5):510-9
Astrocyte elevated gene-1 promotes progression of cervical squamous cell carcinoma by inducing epithelial-mesenchymal transition via Wnt signaling.
Song E, Yu W, Xiong X, Kuang X, Ai Y, Xiong X
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2015 Mar;25(3):345-55
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2015 Mar;25(3):345-55
Rho GDIalpha Modulates Rabbit Trophoblast Stem Cell Survival and Migration.
Zhang J, Li T, Ji W, Yu Y, Tan T
Biology of reproduction 2015 Dec;93(6):144
Biology of reproduction 2015 Dec;93(6):144
Hepatitis B virus hijacks CTHRC1 to evade host immunity and maintain replication.
Bai L, Zhang W, Tan L, Yang H, Ge M, Zhu C, Zhang R, Cao Y, Chen J, Luo Z, Ho W, Liu F, Wu K, Wu J
Journal of molecular cell biology 2015 Dec;7(6):543-56
Journal of molecular cell biology 2015 Dec;7(6):543-56
Activin A induces growth arrest through a SMAD- dependent pathway in hepatic progenitor cells.
Chen L, Zhang W, Liang HF, Zhou QF, Ding ZY, Yang HQ, Liu WB, Wu YH, Man Q, Zhang BX, Chen XP
Cell communication and signaling : CCS 2014 Mar 17;12:18
Cell communication and signaling : CCS 2014 Mar 17;12:18
Notch1 signaling antagonizes transforming growth factor-β pathway and induces apoptosis in rabbit trophoblast stem cells.
Tan T, Lu B, Zhang J, Niu Y, Si W, Wei Q, Ji W
Stem cells and development 2014 Apr 15;23(8):813-22
Stem cells and development 2014 Apr 15;23(8):813-22
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Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Lamin B1 antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human Lamin B1. This antibody recognizes human,mouse,rat antigen. The Lamin B1 antibody has been validated for the following applications: ELISA, WB, IF, FC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Western blot on multiple cells/tissues with anti-LMNB1 (66095-1-Ig) at dilution 1:20000.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells using 66095-1-Ig( Lamin B1 Antibody) at dilution of 1:50 and Rhodamine-Goat anti-Rabbit IgG
- Sample type
- cell line
