Antibody data
- Antibody Data
- Antigen structure
- References [38]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- PA1048 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Lamin B1/LMNB1 Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for Lamin B1/LMNB1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. Lamin B1/LMNB1 information: Molecular Weight: 66408 MW; Subcellular Localization: Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references A novel GATA3 frameshift mutation causes hypoparathyroidism, sensorineural deafness, and renal dysplasia syndrome.
The Role of Sensory Nerves in Dental Pulp Homeostasis: Histological Changes and Cellular Consequences after Sensory Denervation.
SIRT7: A potential prognostic marker and therapeutic target in gallbladder cancer.
Dexmedetomidine abates myocardial ischemia reperfusion injury through inhibition of pyroptosis via regulation of miR-665/MEF2D/Nrf2 axis.
Salvianolic acids from Salvia miltiorrhiza Bunge and their anti-inflammatory effects through the activation of α7nAchR signaling.
Protective Effects of Cannabidiol on Chemotherapy-Induced Oral Mucositis via the Nrf2/Keap1/ARE Signaling Pathways.
Dexmedetomidine attenuates myocardial ischemia/reperfusion-induced ferroptosis via AMPK/GSK-3β/Nrf2 axis.
SIRT4 functions as a tumor suppressor during prostate cancer by inducing apoptosis and inhibiting glutamine metabolism.
rhEPO Upregulates the PPARγ Pathway in Long-term Cultured Primary Nerve Cells via PI3K/Akt to Delay Cell Senescence.
Recombinant human erythropoietin upregulates PPARγ through the PI3K/Akt pathway to protect neurons in rats subjected to oxidative stress.
MicroRNA-1246 suppresses the metastasis of breast cancer cells by targeting the DYRK1A/PGRN axis to prevent the epithelial-mesenchymal transition.
Cellular hnRNPAB interacts with avian influenza viral protein PB2 and inhibits virus replication potentially by restricting PB2 mRNA nuclear export and PB2 protein level.
Neuroprotective Effects of Celastrol on Transient Global Cerebral Ischemia Rats via Regulating HMGB1/NF-κB Signaling Pathway.
Neddylation promotes protein translocation between the cytoplasm and nucleus.
Enhancement of anti-acne effect of Scutellaria baicalensis extract by fermentation with symbiotic fungus Penicillium decumbens.
PBX1 promotes development of natural killer cells by binding directly to the Nfil3 promoter.
Pyrotinib enhances the radiosensitivity of HER2‑overexpressing gastric and breast cancer cells.
Chronic periodontitis induces microbiota-gut-brain axis disorders and cognitive impairment in mice.
Inhibition of HDAC6 attenuates LPS-induced inflammation in macrophages by regulating oxidative stress and suppressing the TLR4-MAPK/NF-κB pathways.
Diabetes aggravates renal ischemia and reperfusion injury in rats by exacerbating oxidative stress, inflammation, and apoptosis.
Propionibacterium acnes related anti-inflammation and skin hydration activities of madecassoside, a pentacyclic triterpene saponin from Centella asiatica.
Targeting KPNB1 overcomes TRAIL resistance by regulating DR5, Mcl-1 and FLIP in glioblastoma cells.
Salidroside Inhibits Lipopolysaccharide-ethanol-induced Activation of Proinflammatory Macrophages via Notch Signaling Pathway.
Enhanced MiR-711 transcription by PPARγ induces endoplasmic reticulum stress-mediated apoptosis targeting calnexin in rat cardiomyocytes after myocardial infarction.
Procyanidin B2 mitigates behavioral impairment and protects myelin integrity in cuprizone-induced schizophrenia in mice.
Regulation of ABCG2 by nuclear factor kappa B affects the sensitivity of human lung adenocarcinoma A549 cells to arsenic trioxide.
3-Dehydroandrographolide protects against lipopolysaccharide-induced inflammation through the cholinergic anti-inflammatory pathway.
Curcumin enhances the anti-cancer effects of Paris Saponin II in lung cancer cells.
Renal ischemia-reperfusion injury attenuated by splenic ischemic preconditioning.
Lanthanum Chloride Inhibits LPS Mediated Expressions of Pro-Inflammatory Cytokines and Adhesion Molecules in HUVECs: Involvement of NF-κB-Jmjd3 Signaling.
Non-Lethal Sonodynamic Therapy Inhibits Atherosclerotic Plaque Progression in ApoE-/- Mice and Attenuates ox-LDL-mediated Macrophage Impairment by Inducing Heme Oxygenase-1.
Glutamine ameliorates lipopolysaccharide-induced cardiac dysfunction by regulating the toll-like receptor 4/mitogen-activated protein kinase/nuclear factor-kB signaling pathway.
Overexpression of DJ-1 reduces oxidative stress and attenuates hypoxia/reoxygenation injury in NRK-52E cells exposed to high glucose.
Hyperglycemia and hyperlipidemia blunts the Insulin-Inpp5f negative feedback loop in the diabetic heart.
Cytoplasmic translocation of HuR contributes to angiotensin II induced cardiac fibrosis.
Tert-butylhydroquinone attenuates scrotal heat-induced damage by regulating Nrf2-antioxidant system in the mouse testis.
Ligustilide ameliorates neuroinflammation and brain injury in focal cerebral ischemia/reperfusion rats: involvement of inhibition of TLR4/peroxiredoxin 6 signaling.
Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility.
Huang B, Li S, Chai Y, Fan Y, Li X, Liu Y, Fu Y, Song X, Cui J
Molecular genetics and metabolism reports 2024 Mar;38:101063
Molecular genetics and metabolism reports 2024 Mar;38:101063
The Role of Sensory Nerves in Dental Pulp Homeostasis: Histological Changes and Cellular Consequences after Sensory Denervation.
Wang C, Liu X, Zhou J, Zhang Q
International journal of molecular sciences 2024 Jan 17;25(2)
International journal of molecular sciences 2024 Jan 17;25(2)
SIRT7: A potential prognostic marker and therapeutic target in gallbladder cancer.
Xu B, Cai X, Cai G, Huang G
Pathology, research and practice 2024 Apr;256:155233
Pathology, research and practice 2024 Apr;256:155233
Dexmedetomidine abates myocardial ischemia reperfusion injury through inhibition of pyroptosis via regulation of miR-665/MEF2D/Nrf2 axis.
Wang L, Liu J, Wang Z, Qian X, Zhao Y, Wang Q, Dai N, Xie Y, Zeng W, Yang W, Bai X, Yang Y, Qian J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115255
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115255
Salvianolic acids from Salvia miltiorrhiza Bunge and their anti-inflammatory effects through the activation of α7nAchR signaling.
Zou LF, Liu DF, Yang H, Zhou CH, Deng SB, Xu NS, He XM, Liu YQ, Shao M, Yu LZ, Liu JS
Journal of ethnopharmacology 2023 Dec 5;317:116743
Journal of ethnopharmacology 2023 Dec 5;317:116743
Protective Effects of Cannabidiol on Chemotherapy-Induced Oral Mucositis via the Nrf2/Keap1/ARE Signaling Pathways.
Li L, Xuan Y, Zhu B, Wang X, Tian X, Zhao L, Wang Y, Jiang X, Wen N
Oxidative medicine and cellular longevity 2022;2022:4619760
Oxidative medicine and cellular longevity 2022;2022:4619760
Dexmedetomidine attenuates myocardial ischemia/reperfusion-induced ferroptosis via AMPK/GSK-3β/Nrf2 axis.
Wang Z, Yao M, Jiang L, Wang L, Yang Y, Wang Q, Qian X, Zhao Y, Qian J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113572
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113572
SIRT4 functions as a tumor suppressor during prostate cancer by inducing apoptosis and inhibiting glutamine metabolism.
Cai G, Ge Z, Xu Y, Cai L, Sun P, Huang G
Scientific reports 2022 Jul 16;12(1):12208
Scientific reports 2022 Jul 16;12(1):12208
rhEPO Upregulates the PPARγ Pathway in Long-term Cultured Primary Nerve Cells via PI3K/Akt to Delay Cell Senescence.
Wang H, Chen M, Zhang T, Gao Z, Gong Y, Yu X, Wu H
Journal of molecular neuroscience : MN 2022 Aug;72(8):1586-1597
Journal of molecular neuroscience : MN 2022 Aug;72(8):1586-1597
Recombinant human erythropoietin upregulates PPARγ through the PI3K/Akt pathway to protect neurons in rats subjected to oxidative stress.
Wang H, Chen M, Zhang T, Gao Z, Gong Y, Yu X, Wu H
The European journal of neuroscience 2022 Aug;56(3):4045-4059
The European journal of neuroscience 2022 Aug;56(3):4045-4059
MicroRNA-1246 suppresses the metastasis of breast cancer cells by targeting the DYRK1A/PGRN axis to prevent the epithelial-mesenchymal transition.
Wang P, Chen W, Zhang Y, Zhong Q, Li Z, Wang Y
Molecular biology reports 2022 Apr;49(4):2711-2721
Molecular biology reports 2022 Apr;49(4):2711-2721
Cellular hnRNPAB interacts with avian influenza viral protein PB2 and inhibits virus replication potentially by restricting PB2 mRNA nuclear export and PB2 protein level.
Ye H, Bi Z, Fan W, Song S, Yan L
Virus research 2021 Nov;305:198573
Virus research 2021 Nov;305:198573
Neuroprotective Effects of Celastrol on Transient Global Cerebral Ischemia Rats via Regulating HMGB1/NF-κB Signaling Pathway.
Zhang B, Zhong Q, Chen X, Wu X, Sha R, Song G, Zhang C, Chen X
Frontiers in neuroscience 2020;14:847
Frontiers in neuroscience 2020;14:847
Neddylation promotes protein translocation between the cytoplasm and nucleus.
Li S, Fang W, Cui Y, Shi H, Chen J, Li L, Zhang L, Zhang X
Biochemical and biophysical research communications 2020 Sep 3;529(4):991-997
Biochemical and biophysical research communications 2020 Sep 3;529(4):991-997
Enhancement of anti-acne effect of Scutellaria baicalensis extract by fermentation with symbiotic fungus Penicillium decumbens.
Zhu X, Mao Y, Guo M, Yu H, Hao L, Hua Q, Lu Z, Hong M, An F
Journal of bioscience and bioengineering 2020 Nov;130(5):457-463
Journal of bioscience and bioengineering 2020 Nov;130(5):457-463
PBX1 promotes development of natural killer cells by binding directly to the Nfil3 promoter.
Xu X, Zhou Y, Fu B, Zhang J, Dong Z, Zhang X, Shen N, Sun R, Tian Z, Wei H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 May;34(5):6479-6492
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 May;34(5):6479-6492
Pyrotinib enhances the radiosensitivity of HER2‑overexpressing gastric and breast cancer cells.
Huang T, Luo X, Wu B, Peng P, Dai Y, Hu G, Qiu H, Yuan X
Oncology reports 2020 Dec;44(6):2634-2644
Oncology reports 2020 Dec;44(6):2634-2644
Chronic periodontitis induces microbiota-gut-brain axis disorders and cognitive impairment in mice.
Xue L, Zou X, Yang XQ, Peng F, Yu DK, Du JR
Experimental neurology 2020 Apr;326:113176
Experimental neurology 2020 Apr;326:113176
Inhibition of HDAC6 attenuates LPS-induced inflammation in macrophages by regulating oxidative stress and suppressing the TLR4-MAPK/NF-κB pathways.
Zhang WB, Yang F, Wang Y, Jiao FZ, Zhang HY, Wang LW, Gong ZJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109166
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109166
Diabetes aggravates renal ischemia and reperfusion injury in rats by exacerbating oxidative stress, inflammation, and apoptosis.
Gong DJ, Wang L, Yang YY, Zhang JJ, Liu XH
Renal failure 2019 Nov;41(1):750-761
Renal failure 2019 Nov;41(1):750-761
Propionibacterium acnes related anti-inflammation and skin hydration activities of madecassoside, a pentacyclic triterpene saponin from Centella asiatica.
Shen X, Guo M, Yu H, Liu D, Lu Z, Lu Y
Bioscience, biotechnology, and biochemistry 2019 Mar;83(3):561-568
Bioscience, biotechnology, and biochemistry 2019 Mar;83(3):561-568
Targeting KPNB1 overcomes TRAIL resistance by regulating DR5, Mcl-1 and FLIP in glioblastoma cells.
Zhu ZC, Liu JW, Yang C, Li MJ, Wu RJ, Xiong ZQ
Cell death & disease 2019 Feb 11;10(2):118
Cell death & disease 2019 Feb 11;10(2):118
Salidroside Inhibits Lipopolysaccharide-ethanol-induced Activation of Proinflammatory Macrophages via Notch Signaling Pathway.
Li JS, Fan LY, Yuan MD, Xing MY
Current medical science 2019 Aug;39(4):526-533
Current medical science 2019 Aug;39(4):526-533
Enhanced MiR-711 transcription by PPARγ induces endoplasmic reticulum stress-mediated apoptosis targeting calnexin in rat cardiomyocytes after myocardial infarction.
Zhao N, Mi L, Zhang X, Xu M, Yu H, Liu Z, Liu X, Guan G, Gao W, Wang J
Journal of molecular and cellular cardiology 2018 May;118:36-45
Journal of molecular and cellular cardiology 2018 May;118:36-45
Procyanidin B2 mitigates behavioral impairment and protects myelin integrity in cuprizone-induced schizophrenia in mice.
Tian H, Sun W, Zhang Q, Li X, Sang Y, Li J, Niu Y, Ding H
RSC advances 2018 Jun 27;8(42):23835-23846
RSC advances 2018 Jun 27;8(42):23835-23846
Regulation of ABCG2 by nuclear factor kappa B affects the sensitivity of human lung adenocarcinoma A549 cells to arsenic trioxide.
Jiang X, Chen C, Gu S, Zhang Z
Environmental toxicology and pharmacology 2018 Jan;57:141-150
Environmental toxicology and pharmacology 2018 Jan;57:141-150
3-Dehydroandrographolide protects against lipopolysaccharide-induced inflammation through the cholinergic anti-inflammatory pathway.
Lu Z, Xie P, Zhang D, Sun P, Yang H, Ye J, Cao H, Huo C, Zhou H, Chen Y, Ye W, Yu L, Liu J
Biochemical pharmacology 2018 Dec;158:305-317
Biochemical pharmacology 2018 Dec;158:305-317
Curcumin enhances the anti-cancer effects of Paris Saponin II in lung cancer cells.
Man S, Zhang L, Cui J, Yang L, Ma L, Gao W
Cell proliferation 2018 Aug;51(4):e12458
Cell proliferation 2018 Aug;51(4):e12458
Renal ischemia-reperfusion injury attenuated by splenic ischemic preconditioning.
Shen Y, Qiu T, Liu XH, Zhang L, Wang ZS, Zhou JQ
European review for medical and pharmacological sciences 2018 Apr;22(7):2134-2142
European review for medical and pharmacological sciences 2018 Apr;22(7):2134-2142
Lanthanum Chloride Inhibits LPS Mediated Expressions of Pro-Inflammatory Cytokines and Adhesion Molecules in HUVECs: Involvement of NF-κB-Jmjd3 Signaling.
Chen X, Xiu M, Xing J, Yu S, Min D, Guo F
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(5):1713-1724
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(5):1713-1724
Non-Lethal Sonodynamic Therapy Inhibits Atherosclerotic Plaque Progression in ApoE-/- Mice and Attenuates ox-LDL-mediated Macrophage Impairment by Inducing Heme Oxygenase-1.
Wang Y, Wang W, Xu H, Sun Y, Sun J, Jiang Y, Yao J, Tian Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;41(6):2432-2446
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;41(6):2432-2446
Glutamine ameliorates lipopolysaccharide-induced cardiac dysfunction by regulating the toll-like receptor 4/mitogen-activated protein kinase/nuclear factor-kB signaling pathway.
Zhang WB, Zhang HY, Zhang Q, Jiao FZ, Zhang H, Wang LW, Gong ZJ
Experimental and therapeutic medicine 2017 Dec;14(6):5825-5832
Experimental and therapeutic medicine 2017 Dec;14(6):5825-5832
Overexpression of DJ-1 reduces oxidative stress and attenuates hypoxia/reoxygenation injury in NRK-52E cells exposed to high glucose.
Shen ZY, Sun Q, Xia ZY, Meng QT, Lei SQ, Zhao B, Tang LH, Xue R, Chen R
International journal of molecular medicine 2016 Sep;38(3):729-36
International journal of molecular medicine 2016 Sep;38(3):729-36
Hyperglycemia and hyperlipidemia blunts the Insulin-Inpp5f negative feedback loop in the diabetic heart.
Bai D, Zhang Y, Shen M, Sun Y, Xia Q, Zhang Y, Liu X, Wang H, Yuan L
Scientific reports 2016 Feb 24;6:22068
Scientific reports 2016 Feb 24;6:22068
Cytoplasmic translocation of HuR contributes to angiotensin II induced cardiac fibrosis.
Bai D, Ge L, Gao Y, Lu X, Wang H, Yang G
Biochemical and biophysical research communications 2015 Aug 7;463(4):1273-7
Biochemical and biophysical research communications 2015 Aug 7;463(4):1273-7
Tert-butylhydroquinone attenuates scrotal heat-induced damage by regulating Nrf2-antioxidant system in the mouse testis.
Li Y, Cao Y, Wang F, Pu S, Zhang Y, Li C
General and comparative endocrinology 2014 Nov 1;208:12-20
General and comparative endocrinology 2014 Nov 1;208:12-20
Ligustilide ameliorates neuroinflammation and brain injury in focal cerebral ischemia/reperfusion rats: involvement of inhibition of TLR4/peroxiredoxin 6 signaling.
Kuang X, Wang LF, Yu L, Li YJ, Wang YN, He Q, Chen C, Du JR
Free radical biology & medicine 2014 Jun;71:165-175
Free radical biology & medicine 2014 Jun;71:165-175
Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility.
Zhu Z, Liu Y, Li K, Liu J, Wang H, Sun B, Xiong Z, Jiang H, Zheng J, Hu Z
Carcinogenesis 2014 Aug;35(8):1901-10
Carcinogenesis 2014 Aug;35(8):1901-10
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti-Lamin B1 antibody, PA1048, Western blottingLane 1: MCF-7 Cell LysateLane 2: HELA Cell Lysate
- Additional image