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- Product number
- 10397-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10397-1-AP, RRID:AB_2134630
- Product name
- LAMP2 antibody
- Antibody type
- Polyclonal
- Description
- LAMP2 antibody (Cat. #10397-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inhibition of NLRP3 inflammasome by MCC950 under hypoxia alleviates photoreceptor apoptosis via inducing autophagy in Müller glia.
Quinic acid regulated TMA/TMAO-related lipid metabolism and vascular endothelial function through gut microbiota to inhibit atherosclerotic.
Glutamine Availability Regulates the Development of Aging Mediated by mTOR Signaling and Autophagy.
IGF-1 as a Potential Therapy for Spinocerebellar Ataxia Type 3.
Autophagy impairment as a key feature for acetaminophen-induced ototoxicity.
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
Cell-specific expression of functional glucose transporter 8 in mammary gland.
The Inhibition of miR-873 Provides Therapeutic Benefit in a Lipopolysaccharide-Induced Neuroinflammatory Model of Parkinson's Disease.
Exendin-4 impairs the autophagic flux to induce apoptosis in pancreatic acinar AR42J cells by down-regulating LAMP-2.
Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers.
Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.
High expression of LAMP2 predicts poor prognosis in patients with esophageal squamous cell carcinoma.
JWA regulates TRAIL-induced apoptosis via MARCH8-mediated DR4 ubiquitination in cisplatin-resistant gastric cancer cells.
Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88.
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.
Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinoma.
The cellular prion protein negatively regulates phagocytosis and cytokine expression in murine bone marrow-derived macrophages.
Perfluorooctane sulfonate blocked autophagy flux and induced lysosome membrane permeabilization in HepG2 cells.
The role of antigen cross-presentation from leukemia blasts on immunity to the leukemia-associated antigen PR1.
Gao S, Li N, Lin Z, Zhong Y, Wang Y, Shen X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23671
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 May 31;38(10):e23671
Quinic acid regulated TMA/TMAO-related lipid metabolism and vascular endothelial function through gut microbiota to inhibit atherosclerotic.
Jin Q, Zhang C, Chen R, Jiang L, Li H, Wu P, Li L
Journal of translational medicine 2024 Apr 15;22(1):352
Journal of translational medicine 2024 Apr 15;22(1):352
Glutamine Availability Regulates the Development of Aging Mediated by mTOR Signaling and Autophagy.
Zhou J, Chen H, Du J, Tai H, Han X, Huang N, Wang X, Gong H, Yang M, Xiao H
Frontiers in pharmacology 2022;13:924081
Frontiers in pharmacology 2022;13:924081
IGF-1 as a Potential Therapy for Spinocerebellar Ataxia Type 3.
Lin YS, Cheng WL, Chang JC, Lin TT, Chao YC, Liu CS
Biomedicines 2022 Feb 21;10(2)
Biomedicines 2022 Feb 21;10(2)
Autophagy impairment as a key feature for acetaminophen-induced ototoxicity.
Zhao T, Zheng T, Yu H, Hu BH, Hu B, Ma P, Yang Y, Yang N, Hu J, Cao T, Chen G, Yan B, Peshoff M, Hatzoglou M, Geng R, Li B, Zheng QY
Cell death & disease 2021 Jan 4;12(1):3
Cell death & disease 2021 Jan 4;12(1):3
Mammalian target of rapamycin signaling pathway is involved in synaptic plasticity of the spinal dorsal horn and neuropathic pain in rats by regulating autophagy.
Hu J, Chen X, Cheng J, Kong F, Xia H, Wu J
Neuroreport 2021 Aug 4;32(11):925-935
Neuroreport 2021 Aug 4;32(11):925-935
Cell-specific expression of functional glucose transporter 8 in mammary gland.
Mardones L, Muñoz K, Villagrán M
Biochemical and biophysical research communications 2021 Aug 27;567:125-130
Biochemical and biophysical research communications 2021 Aug 27;567:125-130
The Inhibition of miR-873 Provides Therapeutic Benefit in a Lipopolysaccharide-Induced Neuroinflammatory Model of Parkinson's Disease.
Wu J, Yu X, Xue K, Wu J, Wang R, Xie X, Li K, Yang Z, Yue J
Oxidative medicine and cellular longevity 2020;2020:8735249
Oxidative medicine and cellular longevity 2020;2020:8735249
Exendin-4 impairs the autophagic flux to induce apoptosis in pancreatic acinar AR42J cells by down-regulating LAMP-2.
Li Z, Zhu S, Huang L, Shang M, Yu C, Zhu H, Han D, Huang H, Yu X, Li X
Biochemical and biophysical research communications 2018 Feb 5;496(2):294-301
Biochemical and biophysical research communications 2018 Feb 5;496(2):294-301
Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers.
Frick P, Sellier C, Mackenzie IRA, Cheng CY, Tahraoui-Bories J, Martinat C, Pasterkamp RJ, Prudlo J, Edbauer D, Oulad-Abdelghani M, Feederle R, Charlet-Berguerand N, Neumann M
Acta neuropathologica communications 2018 Aug 3;6(1):72
Acta neuropathologica communications 2018 Aug 3;6(1):72
Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.
Khan SH, Zhao D, Shah SZ, Hassan MF, Zhu T, Song Z, Zhou X, Yang L
Cellular and molecular neurobiology 2017 May;37(4):717-728
Cellular and molecular neurobiology 2017 May;37(4):717-728
High expression of LAMP2 predicts poor prognosis in patients with esophageal squamous cell carcinoma.
Li L, Wang W, Zhang R, Liu J, Yu J, Wu X, Xu Y, Ma M, Huang J
Cancer biomarkers : section A of Disease markers 2017 Jul 4;19(3):305-311
Cancer biomarkers : section A of Disease markers 2017 Jul 4;19(3):305-311
JWA regulates TRAIL-induced apoptosis via MARCH8-mediated DR4 ubiquitination in cisplatin-resistant gastric cancer cells.
Wang Q, Chen Q, Zhu L, Chen M, Xu W, Panday S, Wang Z, Li A, Røe OD, Chen R, Wang S, Zhang R, Zhou J
Oncogenesis 2017 Jul 3;6(7):e353
Oncogenesis 2017 Jul 3;6(7):e353
Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88.
Into T, Horie T, Inomata M, Gohda J, Inoue JI, Murakami Y, Niida S
Scientific reports 2017 Apr 21;7(1):1009
Scientific reports 2017 Apr 21;7(1):1009
Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway.
Liu J, Wu J, Sun A, Sun Y, Yu X, Liu N, Dong S, Yang F, Zhang L, Zhong X, Xu C, Lu F, Zhang W
Cell & bioscience 2016;6:33
Cell & bioscience 2016;6:33
Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k.
Shi Q, Song X, Liu Z, Wang Y, Wang Y, Fu J, Su C, Xia X, Song E, Song Y
Chemical research in toxicology 2016 Jul 18;29(7):1160-71
Chemical research in toxicology 2016 Jul 18;29(7):1160-71
Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinoma.
Zhang L, Zhang W, Wang YF, Liu B, Zhang WF, Zhao YF, Kulkarni AB, Sun ZJ
Cell death & disease 2015 May 28;6(5):e1771
Cell death & disease 2015 May 28;6(5):e1771
The cellular prion protein negatively regulates phagocytosis and cytokine expression in murine bone marrow-derived macrophages.
Wang M, Zhao D, Yang Y, Liu J, Wang J, Yin X, Yang L, Zhou X
PloS one 2014;9(7):e102785
PloS one 2014;9(7):e102785
Perfluorooctane sulfonate blocked autophagy flux and induced lysosome membrane permeabilization in HepG2 cells.
Yao XF, Cao J, Xu LM, Sun XC, Kang J, Yang G, Jiang LP, Geng CY, Gao CZ, Zhong LF, Ma YF
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2014 May;67:96-104
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2014 May;67:96-104
The role of antigen cross-presentation from leukemia blasts on immunity to the leukemia-associated antigen PR1.
Alatrash G, Ono Y, Sergeeva A, Sukhumalchandra P, Zhang M, St John LS, Yang TH, Ruisaard K, Armistead PM, Mittendorf EA, He H, Qiao N, Rodriguez-Cruz T, Liang S, Clise-Dwyer K, Wieder ED, Lizee G, Lu S, Molldrem JJ
Journal of immunotherapy (Hagerstown, Md. : 1997) 2012 May;35(4):309-20
Journal of immunotherapy (Hagerstown, Md. : 1997) 2012 May;35(4):309-20
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- L02 cells were subjected to SDS PAGE followed by western blot with 10397-1-AP(LAMP2 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using LAMP2 antibody 10397-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 10397-1-AP(LAMP2 antibody) at dilution of 1:50 (under 25x lens)
- Sample type
- tissue
