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Western blot
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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- HPA029100 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA029100, RRID:AB_10795022
- Product name
- Anti-LAMP2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human LAMP2, Gene description: lysosomal-associated membrane protein 2, Alternative Gene Names: CD107b, Validated applications: IHC, WB, Uniprot ID: P13473, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Senescence detection using reflected light.
SORT1/LAMP2-mediated extracellular vesicle secretion and cell adhesion are linked to lenalidomide resistance in multiple myeloma
Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells.
Exploring Metabolic Adaptations to the Acidic Microenvironment of Osteosarcoma Cells Unveils Sphingosine 1-Phosphate as a Valuable Therapeutic Target
Intratumoral acidosis fosters cancer-induced bone pain through the activation of the mesenchymal tumor-associated stroma in bone metastasis from breast carcinoma
Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB activation
Dedic B, Westerberg L, Mosqueda Solís A, Dumont KD, Ruas JL, Thorell A, Näslund E, Spalding KL
Aging cell 2024 Nov;23(11):e14295
Aging cell 2024 Nov;23(11):e14295
SORT1/LAMP2-mediated extracellular vesicle secretion and cell adhesion are linked to lenalidomide resistance in multiple myeloma
Yamamoto T, Nakayama J, Yamamoto Y, Kuroda M, Hattori Y, Ochiya T
Blood Advances 2022;6(8):2480-2495
Blood Advances 2022;6(8):2480-2495
Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells.
Han JH, Kim YK, Kim H, Lee J, Oh MJ, Kim SB, Kim M, Kim KH, Yoon HJ, Lee MS, Minna JD, White MA, Kim HS
Cancer communications (London, England) 2022 Aug;42(8):716-749
Cancer communications (London, England) 2022 Aug;42(8):716-749
Exploring Metabolic Adaptations to the Acidic Microenvironment of Osteosarcoma Cells Unveils Sphingosine 1-Phosphate as a Valuable Therapeutic Target
Cortini M, Armirotti A, Columbaro M, Longo D, Di Pompo G, Cannas E, Maresca A, Errani C, Longhi A, Righi A, Carelli V, Baldini N, Avnet S
Cancers 2021;13(2):311
Cancers 2021;13(2):311
Intratumoral acidosis fosters cancer-induced bone pain through the activation of the mesenchymal tumor-associated stroma in bone metastasis from breast carcinoma
Di Pompo G, Lemma S, Canti L, Rucci N, Ponzetti M, Errani C, Donati D, Russell S, Gillies R, Chano T, Baldini N, Avnet S
Oncotarget 2017;8(33):54478-54496
Oncotarget 2017;8(33):54478-54496
Cancer-associated mesenchymal stroma fosters the stemness of osteosarcoma cells in response to intratumoral acidosis via NF-κB activation
Avnet S, Di Pompo G, Chano T, Errani C, Ibrahim-Hashim A, Gillies R, Donati D, Baldini N
International Journal of Cancer 2017;140(6):1331-1345
International Journal of Cancer 2017;140(6):1331-1345
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Recombinant expression validation
- Main image
- Experimental details
- Western blot analysis in control (vector only transfected HEK293T lysate) and LAMP2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY419414).
- Sample type
- Human
- Protocol
- Protocol
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human kidney and heart muscle tissues using Anti-LAMP2 antibody. Corresponding LAMP2 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
