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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [96]
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- Product number
- 66301-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- LAMP2 antibody
- Antibody type
- Monoclonal
- Description
- LAMP2 antibody (Cat. #66301-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, pig and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgA
- Antibody clone number
- 2D3B9
- Vial size
- 20ul, 150ul
Submitted references Dehydrocostus lactone suppresses gastric cancer progression by targeting ACLY to inhibit fatty acid synthesis and autophagic flux.
Novel mechanistic study of HDAC6 regulation of rheumatoid arthritis via CMA: exploring potential therapeutic targets.
MK8722 initiates early-stage autophagy while inhibiting late-stage autophagy via FASN-dependent reprogramming of lipid metabolism.
Normal transferrin glycosylation does not rule out severe ALG1 deficiency.
Oxidative medicine and cellular longevity the role and mechanism of NCOA4 in ferroptosis induced by intestinal ischemia reperfusion.
TRIM65 promotes renal cell carcinoma through ubiquitination and degradation of BTG3.
Resveratrol attenuates inflammation and fibrosis in rheumatoid arthritis-associated interstitial lung disease via the AKT/TMEM175 pathway.
HSP90 Inhibition Attenuated Isoflurane-Induced Neurotoxicity in Mice and Human Neuroglioma Cells.
GLA Mutations Suppress Autophagy and Stimulate Lysosome Generation in Fabry Disease.
A pan-KRAS degrader for the treatment of KRAS-mutant cancers.
RNF31 alleviates liver steatosis by promoting p53/BNIP3-related mitophagy in hepatocytes.
Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation.
Overexpression of SESN1 improves mitochondrial damage and mitophagy, a potential therapeutic strategy for cognitive dysfunction after anaesthesia.
TRPML1 contributes to antimony-induced nephrotoxicity by initiating ferroptosis via chaperone-mediated autophagy.
Autophagic degradation of MVBs in LSECs promotes Aldosterone induced-HSCs activation.
A Novel Cargo Delivery System-AnCar-Exo(LaIMTS) Ameliorates Arthritis via Specifically Targeting Pro-Inflammatory Macrophages.
Thioredoxin-1 decreases alpha-synuclein induced by MPTP through promoting autophagy-lysosome pathway.
The African swine fever virus MGF300-4L protein is associated with viral pathogenicity by promoting the autophagic degradation of IKKβ and increasing the stability of IκBα.
Optogenetic manipulation of lysosomal physiology and autophagy-dependent clearance of amyloid beta.
Dysregulation of Autophagy Occurs During Congenital Cataract Development in βA3ΔG91 Mice.
TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagy.
Lysosome-Associated Membrane Protein 3 Induces Lysosome-Dependent Cell Death by Impairing Autophagic Caspase 8 Degradation in the Salivary Glands of Individuals With Sjögren's Disease.
WBP2 restrains the lysosomal degradation of GPX4 to inhibit ferroptosis in cisplatin-induced acute kidney injury.
Realgar-Induced Neurotoxicity: Crosstalk Between the Autophagic Flux and the p62-NRF2 Feedback Loop Mediates p62 Accumulation to Promote Apoptosis.
Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stress.
Mitophagy and mitochondrion-related expression profiles in response to physiological and pathological hypoxia in the corneal epithelium.
Modulation of hepatic transcription factor EB activity during cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by Pla2g15.
RAB7A GTPase Is Involved in Mitophagosome Formation and Autophagosome-Lysosome Fusion in N2a Cells Treated with the Prion Protein Fragment 106-126.
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.
Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition.
TFEB coordinates autophagy and pyroptosis as hepatotoxicity responses to ZnO nanoparticles.
Loss of LncRNA DUXAP8 synergistically enhanced sorafenib induced ferroptosis in hepatocellular carcinoma via SLC7A11 de-palmitoylation.
Autophagy and exosomes coordinately mediate quercetin's protective effects on alcoholic liver disease.
The human discs large protein 1 interacts with and maintains connexin 43 at the plasma membrane in keratinocytes.
Stromal cell-derived small extracellular vesicles enhance radioresistance of prostate cancer cells via interleukin-8-induced autophagy.
Autophagic response of intestinal epithelial cells exposed to polystyrene nanoplastics.
Zhachong Shisanwei Pill resists ischemic stroke by lysosome pathway based on proteomics and bioinformatics.
Impaired autophagy flux by lncRNA NEAT1 is critical for inflammation factors production in human periodontal ligament stem cells with nicotine treatment.
Deficiency of cancer/testis antigen gene CT55 causes male infertility in humans and mice.
Folate inhibits lipid deposition via the autophagy pathway in chicken hepatocytes.
Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming.
Corilagin attenuates intestinal ischemia/reperfusion injury in mice by inhibiting ferritinophagy-mediated ferroptosis through disrupting NCOA4-ferritin interaction.
Targeting ANXA7/LAMP5-mTOR axis attenuates spinal cord injury by inhibiting neuronal apoptosis via enhancing autophagy in mice.
HOXA1 participates in VSMC-to-macrophage-like cell transformation via regulation of NF-κB p65 and KLF4: a potential mechanism of atherosclerosis pathogenesis.
Cadmium-induced impairment of spermatozoa development by reducing exosomal-MVBs secretion: a novel pathway.
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Liensinine Inhibits Cell Growth and Blocks Autophagic Flux in Nonsmall-Cell Lung Cancer.
Prototheca bovis induces autophagy in bovine mammary epithelial cells via the HIF-1α and AMPKα/ULK1 pathway.
YAP1 alleviates sepsis-induced acute lung injury via inhibiting ferritinophagy-mediated ferroptosis.
RRM2 Mediates the Anti-Tumor Effect of the Natural Product Pectolinarigenin on Glioblastoma Through Promoting CDK1 Protein Degradation by Increasing Autophagic Flux.
The effect of aerobic exercise on the lipophagy of adipose tissue in obese male mice.
Paternal cadmium exposure affects testosterone synthesis by reducing the testicular cholesterol pool in offspring mice.
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
YAP1 protects against septic liver injury via ferroptosis resistance.
Berbamine hydrochloride inhibits bovine viral diarrhea virus replication via interfering in late-stage autophagy.
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Ppt1-deficiency dysregulates lysosomal Ca(++) homeostasis contributing to pathogenesis in a mouse model of CLN1 disease.
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PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer.
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GPX4 degradation via chaperone-mediated autophagy contributes to antimony-triggered neuronal ferroptosis.
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Fatty acid binding protein 3 deficiency limits atherosclerosis development via macrophage foam cell formation inhibition.
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Identification of BAG2 and Cathepsin D as Plasma Biomarkers for Parkinson's Disease.
Atmospheric particulate matter impedes autophagic flux by impairing lysosomal milieu and integrity in human umbilical vein endothelial cells (HUVECs).
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca(2+)/CaMKII signal pathway.
Carbon monoxide alleviates senescence in diabetic nephropathy by improving autophagy.
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Legumain promotes tubular ferroptosis by facilitating chaperone-mediated autophagy of GPX4 in AKI.
Mutation analysis of MFSD8 in an amyotrophic lateral sclerosis cohort from mainland China.
Classical swine fever virus infection suppresses claudin-1 expression to facilitate its replication in PK-15 cells.
Nlp promotes autophagy through facilitating the interaction of Rab7 and FYCO1.
Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway.
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Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
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MK8722 initiates early-stage autophagy while inhibiting late-stage autophagy via FASN-dependent reprogramming of lipid metabolism.
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Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation.
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TRPML1 contributes to antimony-induced nephrotoxicity by initiating ferroptosis via chaperone-mediated autophagy.
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Autophagic degradation of MVBs in LSECs promotes Aldosterone induced-HSCs activation.
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Thioredoxin-1 decreases alpha-synuclein induced by MPTP through promoting autophagy-lysosome pathway.
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Cell death discovery 2024 Feb 22;10(1):93
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The African swine fever virus MGF300-4L protein is associated with viral pathogenicity by promoting the autophagic degradation of IKKβ and increasing the stability of IκBα.
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TRPM2 protects against cisplatin-induced acute kidney injury and mitochondrial dysfunction via modulating autophagy.
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Arthritis & rheumatology (Hoboken, N.J.) 2023 Sep;75(9):1586-1598
WBP2 restrains the lysosomal degradation of GPX4 to inhibit ferroptosis in cisplatin-induced acute kidney injury.
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Realgar-Induced Neurotoxicity: Crosstalk Between the Autophagic Flux and the p62-NRF2 Feedback Loop Mediates p62 Accumulation to Promote Apoptosis.
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Molecular neurobiology 2023 Oct;60(10):6001-6017
Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stress.
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eLife 2023 Oct 30;12
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Mitophagy and mitochondrion-related expression profiles in response to physiological and pathological hypoxia in the corneal epithelium.
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Modulation of hepatic transcription factor EB activity during cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by Pla2g15.
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bioRxiv : the preprint server for biology 2023 Nov 10;
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RAB7A GTPase Is Involved in Mitophagosome Formation and Autophagosome-Lysosome Fusion in N2a Cells Treated with the Prion Protein Fragment 106-126.
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Autophagy 2023 Mar;19(3):839-857
Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition.
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The Journal of experimental medicine 2023 Mar 6;220(3)
TFEB coordinates autophagy and pyroptosis as hepatotoxicity responses to ZnO nanoparticles.
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The Science of the total environment 2023 Mar 20;865:161242
The Science of the total environment 2023 Mar 20;865:161242
Loss of LncRNA DUXAP8 synergistically enhanced sorafenib induced ferroptosis in hepatocellular carcinoma via SLC7A11 de-palmitoylation.
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Clinical and translational medicine 2023 Jun;13(6):e1300
Clinical and translational medicine 2023 Jun;13(6):e1300
Autophagy and exosomes coordinately mediate quercetin's protective effects on alcoholic liver disease.
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The Journal of nutritional biochemistry 2023 Jun;116:109332
The Journal of nutritional biochemistry 2023 Jun;116:109332
The human discs large protein 1 interacts with and maintains connexin 43 at the plasma membrane in keratinocytes.
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Journal of cell science 2023 Jun 1;136(11)
Stromal cell-derived small extracellular vesicles enhance radioresistance of prostate cancer cells via interleukin-8-induced autophagy.
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Journal of extracellular vesicles 2023 Jul;12(7):e12342
Autophagic response of intestinal epithelial cells exposed to polystyrene nanoplastics.
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Environmental toxicology 2023 Jan;38(1):205-215
Environmental toxicology 2023 Jan;38(1):205-215
Zhachong Shisanwei Pill resists ischemic stroke by lysosome pathway based on proteomics and bioinformatics.
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Journal of ethnopharmacology 2023 Jan 30;301:115766
Impaired autophagy flux by lncRNA NEAT1 is critical for inflammation factors production in human periodontal ligament stem cells with nicotine treatment.
Zhang T, Yang K, Chen Y, Jiang Y, Zhou Z, Liu J, Du Y, Wang L, Han X, Wu X, Wang X
Journal of periodontal research 2023 Feb;58(1):70-82
Journal of periodontal research 2023 Feb;58(1):70-82
Deficiency of cancer/testis antigen gene CT55 causes male infertility in humans and mice.
Zhang G, Jiang C, Yang Y, Wang Y, Zhou H, Dai S, Liu M, Yang Y, Yang L, Shen Q, Zhang T, Zhang X, Yang Y, Shen Y
Cell death and differentiation 2023 Feb;30(2):500-514
Cell death and differentiation 2023 Feb;30(2):500-514
Folate inhibits lipid deposition via the autophagy pathway in chicken hepatocytes.
Du ZQ, Pang YQ, Zhang Y, Wang L, Zhang R, Li H, Yang CX
Poultry science 2023 Feb;102(2):102363
Poultry science 2023 Feb;102(2):102363
Serine hydroxymethyltransferase 2 knockdown induces apoptosis in ccRCC by causing lysosomal membrane permeabilization via metabolic reprogramming.
Liu Z, Fan M, Hou J, Pan S, Xu Y, Zhang H, Liu C, Hao X, Li X, Wang H
Cell death & disease 2023 Feb 20;14(2):144
Cell death & disease 2023 Feb 20;14(2):144
Corilagin attenuates intestinal ischemia/reperfusion injury in mice by inhibiting ferritinophagy-mediated ferroptosis through disrupting NCOA4-ferritin interaction.
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Life sciences 2023 Dec 1;334:122176
Life sciences 2023 Dec 1;334:122176
Targeting ANXA7/LAMP5-mTOR axis attenuates spinal cord injury by inhibiting neuronal apoptosis via enhancing autophagy in mice.
Li N, Chen L, Zhao X, Gu C, Chang Y, Feng S
Cell death discovery 2023 Aug 24;9(1):309
Cell death discovery 2023 Aug 24;9(1):309
HOXA1 participates in VSMC-to-macrophage-like cell transformation via regulation of NF-κB p65 and KLF4: a potential mechanism of atherosclerosis pathogenesis.
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Molecular medicine (Cambridge, Mass.) 2023 Aug 1;29(1):104
Molecular medicine (Cambridge, Mass.) 2023 Aug 1;29(1):104
Cadmium-induced impairment of spermatozoa development by reducing exosomal-MVBs secretion: a novel pathway.
Ali W, Bian Y, Ali H, Sun J, Zhu J, Ma Y, Liu Z, Zou H
Aging 2023 Apr 25;15(10):4096-4107
Aging 2023 Apr 25;15(10):4096-4107
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Li J, Bai J, Si X, Jia H, Wu Z
Chemico-biological interactions 2023 Apr 1;374:110386
Chemico-biological interactions 2023 Apr 1;374:110386
Liensinine Inhibits Cell Growth and Blocks Autophagic Flux in Nonsmall-Cell Lung Cancer.
Chang M, Ding S, Dong X, Shang X, Li Y, Xie L, Song X, Song X
Journal of oncology 2022;2022:1533779
Journal of oncology 2022;2022:1533779
Prototheca bovis induces autophagy in bovine mammary epithelial cells via the HIF-1α and AMPKα/ULK1 pathway.
Zhao W, Xu M, Barkema HW, Xie X, Lin Y, Khan S, Kastelic JP, Wang D, Deng Z, Han B
Frontiers in immunology 2022;13:934819
Frontiers in immunology 2022;13:934819
YAP1 alleviates sepsis-induced acute lung injury via inhibiting ferritinophagy-mediated ferroptosis.
Zhang J, Zheng Y, Wang Y, Wang J, Sang A, Song X, Li X
Frontiers in immunology 2022;13:884362
Frontiers in immunology 2022;13:884362
RRM2 Mediates the Anti-Tumor Effect of the Natural Product Pectolinarigenin on Glioblastoma Through Promoting CDK1 Protein Degradation by Increasing Autophagic Flux.
Jiang H, Zhang D, Aleksandrovich KD, Ye J, Wang L, Chen X, Gao M, Wang X, Yan T, Yang H, Lu E, Liu W, Zhang C, Wu J, Yao P, Sun Z, Rong X, Timofeevich SA, Mahmutovich SS, Zheng Z, Chen X, Zhao S
Frontiers in oncology 2022;12:887294
Frontiers in oncology 2022;12:887294
The effect of aerobic exercise on the lipophagy of adipose tissue in obese male mice.
Li R, Li G, Hai Y, Li T, Bian Y, Ma T
Chemistry and physics of lipids 2022 Sep;247:105225
Chemistry and physics of lipids 2022 Sep;247:105225
Paternal cadmium exposure affects testosterone synthesis by reducing the testicular cholesterol pool in offspring mice.
Zhou J, Zhang Y, Zeng L, Wang X, Mu H, Wang M, Pan H, Su P
Ecotoxicology and environmental safety 2022 Sep 1;242:113947
Ecotoxicology and environmental safety 2022 Sep 1;242:113947
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13661-13675
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13661-13675
YAP1 protects against septic liver injury via ferroptosis resistance.
Wang J, Zhu Q, Li R, Zhang J, Ye X, Li X
Cell & bioscience 2022 Oct 1;12(1):163
Cell & bioscience 2022 Oct 1;12(1):163
Berbamine hydrochloride inhibits bovine viral diarrhea virus replication via interfering in late-stage autophagy.
Wang J, Yang G, Zhang L, Zhang J, Wang J, Zou Y, Wang J
Virus research 2022 Nov;321:198905
Virus research 2022 Nov;321:198905
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Ppt1-deficiency dysregulates lysosomal Ca(++) homeostasis contributing to pathogenesis in a mouse model of CLN1 disease.
Mondal A, Appu AP, Sadhukhan T, Bagh MB, Previde RM, Sadhukhan S, Stojilkovic S, Liu A, Mukherjee AB
Journal of inherited metabolic disease 2022 May;45(3):635-656
Journal of inherited metabolic disease 2022 May;45(3):635-656
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.
Jiang B, Zhang J, Zhao G, Liu M, Hu J, Lin F, Wang J, Zhao W, Ma H, Zhang C, Wu C, Yao L, Liu Q, Chen X, Cao Y, Zheng Y, Zhang C, Han A, Lin D, Li Q
Molecular cell 2022 May 19;82(10):1821-1835.e6
Molecular cell 2022 May 19;82(10):1821-1835.e6
Progranulin Insufficiency Affects Lysosomal Homeostasis in Retinal Pigment Epithelium.
Takahashi K, Nakamura S, Shimazawa M, Hara H
In vivo (Athens, Greece) 2022 Mar-Apr;36(2):610-617
In vivo (Athens, Greece) 2022 Mar-Apr;36(2):610-617
Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy.
Liu C, Sun W, Zhu T, Shi S, Zhang J, Wang J, Gao F, Ou Q, Jin C, Li J, Xu JY, Zhang J, Tian H, Xu GT, Lu L
Redox biology 2022 Jun;52:102292
Redox biology 2022 Jun;52:102292
SUMO2-mediated SUMOylation of SH3GLB1 promotes ionizing radiation-induced hypertrophic cardiomyopathy through mitophagy activation.
Gao A, Zou J, Mao Z, Zhou H, Zeng G
European journal of pharmacology 2022 Jun 5;924:174980
European journal of pharmacology 2022 Jun 5;924:174980
Integrated metabolism and epigenetic modifications in the macrophages of mice in responses to cold stress.
Lu J, Fu S, Dai J, Hu J, Li S, Ji H, Wang Z, Yu J, Bao J, Xu B, Guo J, Yang H
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
Journal of Zhejiang University. Science. B 2022 Jun 15;23(6):461-480
CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis.
Tan J, Xu T, Gou Y, Wang H, Liang Z, Cao Y, Wang H, Yu Y, Jiao N, Zhang Z
Stem cell research & therapy 2022 Jul 15;13(1):294
Stem cell research & therapy 2022 Jul 15;13(1):294
PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer.
Salvi A, Young AN, Huntsman AC, Pergande MR, Korkmaz MA, Rathnayake RA, Mize BK, Kinghorn AD, Zhang X, Ratia K, Schirle M, Thomas JR, Brittain SM, Shelton C, Aldrich LN, Cologna SM, Fuchs JR, Burdette JE
Cell death & disease 2022 Jan 10;13(1):45
Cell death & disease 2022 Jan 10;13(1):45
Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansion.
Tanishita Y, Sekiya H, Inohara N, Tsuchiya K, Mitsuyama M, Núñez G, Hara H
Cell reports 2022 Feb 22;38(8):110414
Cell reports 2022 Feb 22;38(8):110414
Toosendanin Induces Hepatocyte Damage by Inhibiting Autophagic Flux via TFEB-Mediated Lysosomal Dysfunction.
Luo L, Liang Y, Fu Y, Liang Z, Zheng J, Lan J, Shen F, Huang Z
Pharmaceuticals (Basel, Switzerland) 2022 Dec 3;15(12)
Pharmaceuticals (Basel, Switzerland) 2022 Dec 3;15(12)
Incomplete autophagy promotes the proliferation of Mycoplasma hyopneumoniae through the JNK and Akt pathways in porcine alveolar macrophages.
Wen Y, Chen Z, Tian Y, Yang M, Dong Q, Yang Y, Ding H
Veterinary research 2022 Aug 4;53(1):62
Veterinary research 2022 Aug 4;53(1):62
GPX4 degradation via chaperone-mediated autophagy contributes to antimony-triggered neuronal ferroptosis.
Yu S, Li Z, Zhang Q, Wang R, Zhao Z, Ding W, Wang F, Sun C, Tang J, Wang X, Zhang H, Huang R, Wu Q, Jiang J, Zhao X
Ecotoxicology and environmental safety 2022 Apr 1;234:113413
Ecotoxicology and environmental safety 2022 Apr 1;234:113413
Chaperone-mediated autophagy plays an important role in regulating retinal progenitor cell homeostasis.
Jin C, Ou Q, Chen J, Wang T, Zhang J, Wang Z, Wang Y, Tian H, Xu JY, Gao F, Wang J, Li J, Lu L, Xu GT
Stem cell research & therapy 2022 Apr 1;13(1):136
Stem cell research & therapy 2022 Apr 1;13(1):136
PINK1 Alleviates Cognitive Impairments via Attenuating Pathological Tau Aggregation in a Mouse Model of Tauopathy.
Jiang XJ, Wu YQ, Ma R, Chang YM, Li LL, Zhu JH, Liu GP, Li G
Frontiers in cell and developmental biology 2021;9:736267
Frontiers in cell and developmental biology 2021;9:736267
Bhlhe40/Sirt1 Axis-Regulated Mitophagy Is Implicated in All-Trans Retinoic Acid-Induced Spina Bifida Aperta.
Zhao L, Liu D, Ma W, Gu H, Wei X, Luo W, Yuan Z
Frontiers in cell and developmental biology 2021;9:644346
Frontiers in cell and developmental biology 2021;9:644346
Sodium-Glucose Co-transporter-2 Inhibitor of Dapagliflozin Attenuates Myocardial Ischemia/Reperfusion Injury by Limiting NLRP3 Inflammasome Activation and Modulating Autophagy.
Yu YW, Que JQ, Liu S, Huang KY, Qian L, Weng YB, Rong FN, Wang L, Zhou YY, Xue YJ, Ji KT
Frontiers in cardiovascular medicine 2021;8:768214
Frontiers in cardiovascular medicine 2021;8:768214
SARS-CoV-2 Causes Mitochondrial Dysfunction and Mitophagy Impairment.
Shang C, Liu Z, Zhu Y, Lu J, Ge C, Zhang C, Li N, Jin N, Li Y, Tian M, Li X
Frontiers in microbiology 2021;12:780768
Frontiers in microbiology 2021;12:780768
The Extracellular Matrix Enriched With Exosomes for the Treatment on Pulmonary Fibrosis in Mice.
Yu Y, Liu X, Zhao Z, Xu Z, Qiao Y, Zhou Y, Qiao H, Zhong J, Dai J, Suo G
Frontiers in pharmacology 2021;12:747223
Frontiers in pharmacology 2021;12:747223
Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH.
Zeng H, Chen H, Li M, Zhuang J, Peng Y, Zhou H, Xu C, Yu Q, Fu X, Cao S, Cai J, Yan F, Chen G
Journal of neuroinflammation 2021 Sep 16;18(1):210
Journal of neuroinflammation 2021 Sep 16;18(1):210
CLEC5A knockdown protects against cardiac dysfunction after myocardial infarction by suppressing macrophage polarization, NLRP3 inflammasome activation, and pyroptosis.
Wang X, Hu Y, Wang Y, Shen D, Tao G
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Oct;99(5):655-665
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Oct;99(5):655-665
Sorting nexin 3 induces heart failure via promoting retromer-dependent nuclear trafficking of STAT3.
Lu J, Xu S, Huo Y, Sun D, Hu Y, Wang J, Zhang X, Wang P, Li Z, Liang M, Wu Z, Liu P
Cell death and differentiation 2021 Oct;28(10):2871-2887
Cell death and differentiation 2021 Oct;28(10):2871-2887
Cordycepin inhibits cell senescence by ameliorating lysosomal dysfunction and inducing autophagy through the AMPK and mTOR-p70S6K pathway.
Zuo SQ, Li C, Liu YL, Tan YH, Wan X, Xu T, Li Q, Wang L, Wu YL, Deng FM, Tang B
FEBS open bio 2021 Oct;11(10):2705-2714
FEBS open bio 2021 Oct;11(10):2705-2714
Reactive Oxygen Species Mediate 6c-Induced Mitochondrial and Lysosomal Dysfunction, Autophagic Cell Death, and DNA Damage in Hepatocellular Carcinoma.
Wang S, Xu X, Che D, Fan R, Gao M, Cao Y, Ge C, Feng Y, Li J, Xie S, Wang C, Dai F, Gao L, Wang Y
International journal of molecular sciences 2021 Oct 12;22(20)
International journal of molecular sciences 2021 Oct 12;22(20)
Fatty acid binding protein 3 deficiency limits atherosclerosis development via macrophage foam cell formation inhibition.
Tan L, Lu J, Liu L, Li L
Experimental cell research 2021 Oct 1;407(1):112768
Experimental cell research 2021 Oct 1;407(1):112768
Glucose-induced decrease of cystathionine β-synthase mediates renal injuries.
Yu Y, Xiao L, Ren Z, Zhu G, Wang W, Jia Y, Peng A, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21576
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21576
Identification of BAG2 and Cathepsin D as Plasma Biomarkers for Parkinson's Disease.
Kang J, Kim JW, Heo H, Lee J, Park KY, Yoon JH, Chang J
Clinical and translational science 2021 Mar;14(2):606-616
Clinical and translational science 2021 Mar;14(2):606-616
Atmospheric particulate matter impedes autophagic flux by impairing lysosomal milieu and integrity in human umbilical vein endothelial cells (HUVECs).
Wang Y, Liu N, Huang X, Hu W, Ma Y, Liang Y, Xie W, Tang M
The Science of the total environment 2021 Mar 20;761:143290
The Science of the total environment 2021 Mar 20;761:143290
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca(2+)/CaMKII signal pathway.
Chen TT, Zhou X, Xu YN, Li Y, Wu XY, Xiang Q, Fu LY, Hu XX, Tao L, Shen XC
Aging 2021 Mar 10;13(7):9542-9565
Aging 2021 Mar 10;13(7):9542-9565
Carbon monoxide alleviates senescence in diabetic nephropathy by improving autophagy.
Chen L, Mei G, Jiang C, Cheng X, Li D, Zhao Y, Chen H, Wan C, Yao P, Gao C, Tang Y
Cell proliferation 2021 Jun;54(6):e13052
Cell proliferation 2021 Jun;54(6):e13052
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Zhu Q, Liu Z, Wang Y, Song E, Song Y
Journal of hazardous materials 2021 Jun 5;411:124958
Journal of hazardous materials 2021 Jun 5;411:124958
Legumain promotes tubular ferroptosis by facilitating chaperone-mediated autophagy of GPX4 in AKI.
Chen C, Wang D, Yu Y, Zhao T, Min N, Wu Y, Kang L, Zhao Y, Du L, Zhang M, Gong J, Zhang Z, Zhang Y, Mi X, Yue S, Tan X
Cell death & disease 2021 Jan 11;12(1):65
Cell death & disease 2021 Jan 11;12(1):65
Mutation analysis of MFSD8 in an amyotrophic lateral sclerosis cohort from mainland China.
Huang L, Liu Z, Yuan Y, Shen L, Jiang H, Tang B, Wang J, Lei L
The European journal of neuroscience 2021 Feb;53(4):1197-1206
The European journal of neuroscience 2021 Feb;53(4):1197-1206
Classical swine fever virus infection suppresses claudin-1 expression to facilitate its replication in PK-15 cells.
Wang X, Yang Y, Yang X, Liu X, Wang X, Gao L, Yang C, Lan R, Bi J, Zhao Q, Yang G, Wang J, Lin Y, Liu J, Yin G
Microbial pathogenesis 2021 Aug;157:105012
Microbial pathogenesis 2021 Aug;157:105012
Nlp promotes autophagy through facilitating the interaction of Rab7 and FYCO1.
Xiao W, Yeerken D, Li J, Li Z, Jiang L, Li D, Fu M, Ma L, Song Y, Zhang W, Zhan Q
Signal transduction and targeted therapy 2021 Apr 16;6(1):152
Signal transduction and targeted therapy 2021 Apr 16;6(1):152
Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway.
Yang Y, Wang Q, Song D, Zen R, Zhang L, Wang Y, Yang H, Zhang D, Jia J, Zhang J, Wang J
Journal of experimental & clinical cancer research : CR 2020 Sep 22;39(1):197
Journal of experimental & clinical cancer research : CR 2020 Sep 22;39(1):197
3-Acetyldeoxynivalenol induces lysosomal membrane permeabilization-mediated apoptosis and inhibits autophagic flux in macrophages.
Liu N, Yang Y, Chen J, Jia H, Zhang Y, Jiang D, Wu G, Wu Z
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt B):114697
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt B):114697
Inhibition of PCSK9 potentiates immune checkpoint therapy for cancer.
Liu X, Bao X, Hu M, Chang H, Jiao M, Cheng J, Xie L, Huang Q, Li F, Li CY
Nature 2020 Dec;588(7839):693-698
Nature 2020 Dec;588(7839):693-698
Butyrate-mediated autophagy inhibition limits cytosolic Salmonella Infantis replication in the colon of pigs treated with a mixture of Lactobacillus and Bacillus.
Chu B, Zhu Y, Su J, Xia B, Zou Y, Nie J, Zhang W, Wang J
Veterinary research 2020 Aug 5;51(1):99
Veterinary research 2020 Aug 5;51(1):99
TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation.
Zhang H, Tian X, Lu X, Xu D, Guo Y, Dong Z, Li Y, Ma Y, Chen C, Yang Y, Yang M, Yang Y, Liu F, Zhou R, He M, Xiao F, Wang X
The Journal of clinical investigation 2019 Sep 3;129(9):3864-3876
The Journal of clinical investigation 2019 Sep 3;129(9):3864-3876
Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance.
Liu Y, Tang J, Liu D, Zhang L, He Y, Li J, Gao L, Tang D, Jin X, Kong D
Cell death & disease 2018 Apr 1;9(4):419
Cell death & disease 2018 Apr 1;9(4):419
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