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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [2]
- Flow cytometry [1]
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- Product number
- AF2480 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rabbit Polyclonal HGFR/c-MET Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human and mouse HGF R/c-MET when phosphorylated at Y1234/Y1235 in Western blots.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Reviving oncogenic addiction to MET bypassed by BRAF (G469A) mutation.
Antiproliferative effects of the CDK6 inhibitor PD0332991 and its effect on signaling networks in gastric cancer cells.
Pulmonary pericytes regulate lung morphogenesis.
Dual MET/EGFR therapy leads to complete response and resistance prevention in a MET-amplified gastroesophageal xenopatient cohort.
Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines.
Protein signatures for classification and prognosis of gastric cancer a signaling pathway-based approach.
Alternative proteolytic processing of hepatocyte growth factor during wound repair.
Combined inhibition of MET and EGFR suppresses proliferation of malignant mesothelioma cells.
Virzì AR, Gentile A, Benvenuti S, Comoglio PM
Proceedings of the National Academy of Sciences of the United States of America 2018 Oct 2;115(40):10058-10063
Proceedings of the National Academy of Sciences of the United States of America 2018 Oct 2;115(40):10058-10063
Antiproliferative effects of the CDK6 inhibitor PD0332991 and its effect on signaling networks in gastric cancer cells.
Wang D, Sun Y, Li W, Ye F, Zhang Y, Guo Y, Zhang DY, Suo J
International journal of molecular medicine 2018 May;41(5):2473-2484
International journal of molecular medicine 2018 May;41(5):2473-2484
Pulmonary pericytes regulate lung morphogenesis.
Kato K, Diéguez-Hurtado R, Park DY, Hong SP, Kato-Azuma S, Adams S, Stehling M, Trappmann B, Wrana JL, Koh GY, Adams RH
Nature communications 2018 Jun 22;9(1):2448
Nature communications 2018 Jun 22;9(1):2448
Dual MET/EGFR therapy leads to complete response and resistance prevention in a MET-amplified gastroesophageal xenopatient cohort.
Apicella M, Migliore C, Capelôa T, Menegon S, Cargnelutti M, Degiuli M, Sapino A, Sottile A, Sarotto I, Casorzo L, Cassoni P, De Simone M, Comoglio PM, Marsoni S, Corso S, Giordano S
Oncogene 2017 Mar 2;36(9):1200-1210
Oncogene 2017 Mar 2;36(9):1200-1210
Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines.
Phillip CJ, Zaman S, Shentu S, Balakrishnan K, Zhang J, Baladandayuthapani V, Taverna P, Redkar S, Wang M, Stellrecht CM, Gandhi V
Journal of hematology & oncology 2013 Dec 10;6:92
Journal of hematology & oncology 2013 Dec 10;6:92
Protein signatures for classification and prognosis of gastric cancer a signaling pathway-based approach.
Wang D, Ye F, Sun Y, Li W, Liu H, Jiang J, Zhang Y, Liu C, Tong W, Gao L, Sun Y, Zhang W, Seetoe T, Lee P, Suo J, Zhang DY
The American journal of pathology 2011 Oct;179(4):1657-66
The American journal of pathology 2011 Oct;179(4):1657-66
Alternative proteolytic processing of hepatocyte growth factor during wound repair.
Buchstein N, Hoffmann D, Smola H, Lang S, Paulsson M, Niemann C, Krieg T, Eming SA
The American journal of pathology 2009 Jun;174(6):2116-28
The American journal of pathology 2009 Jun;174(6):2116-28
Combined inhibition of MET and EGFR suppresses proliferation of malignant mesothelioma cells.
Kawaguchi K, Murakami H, Taniguchi T, Fujii M, Kawata S, Fukui T, Kondo Y, Osada H, Usami N, Yokoi K, Ueda Y, Yatabe Y, Ito M, Horio Y, Hida T, Sekido Y
Carcinogenesis 2009 Jul;30(7):1097-105
Carcinogenesis 2009 Jul;30(7):1097-105
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human Phospho-HGF R/c-MET (Y1234/Y1235) by Simple WesternTM. Detection of Human Phospho-HGF R/c-MET (Y1234/Y1235) by Simple WesternTM.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human Phospho-HGF R/c-MET (Y1234/Y1235) by Western Blot. Detection of Human Phospho-HGF R/c-MET (Y1234/Y1235) by Western Blot.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- HGF R/c-MET in Mouse Embryo. HGF R/c-MET in Mouse Embryo.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- HGF R/c-MET in Human Renal Cell Carcinoma Tissue. HGF R/c-MET in Human Renal Cell Carcinoma Tissue.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of HGF R/c-MET in pervanadate-treated MCF-7 Human Cell Line by Flow Cytometry. Detection of HGF R/c-MET in pervanadate-treated MCF-7 Human Cell Line by Flow Cytometry.
