Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- MAB1147 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB1147, RRID:AB_1577212
- Product name
- MET monoclonal antibody, clone 4AT247
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against partial recombinant MET.
- Isotype
- IgG
- Antibody clone number
- 4AT247
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Increased HGF and c-Met in muscle tissues of polymyositis and dermatomyositis patients: beneficial roles of HGF in muscle regeneration.
Further evidence for the role of MET in autism susceptibility.
MET receptor sequence variants R970C and T992I lack transforming capacity.
Sugiura T, Kawaguchi Y, Soejima M, Katsumata Y, Gono T, Baba S, Kawamoto M, Murakawa Y, Yamanaka H, Hara M
Clinical immunology (Orlando, Fla.) 2010 Sep;136(3):387-99
Clinical immunology (Orlando, Fla.) 2010 Sep;136(3):387-99
Further evidence for the role of MET in autism susceptibility.
Thanseem I, Nakamura K, Miyachi T, Toyota T, Yamada S, Tsujii M, Tsuchiya KJ, Anitha A, Iwayama Y, Yamada K, Hattori E, Matsuzaki H, Matsumoto K, Iwata Y, Suzuki K, Suda S, Kawai M, Sugihara G, Takebayashi K, Takei N, Ichikawa H, Sugiyama T, Yoshikawa T, Mori N
Neuroscience research 2010 Oct;68(2):137-41
Neuroscience research 2010 Oct;68(2):137-41
MET receptor sequence variants R970C and T992I lack transforming capacity.
Tyner JW, Fletcher LB, Wang EQ, Yang WF, Rutenberg-Schoenberg ML, Beadling C, Mori M, Heinrich MC, Deininger MW, Druker BJ, Loriaux MM
Cancer research 2010 Aug 1;70(15):6233-7
Cancer research 2010 Aug 1;70(15):6233-7
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Detection of endogenous MET in HepG2 cell line. 10 ug/lane of HepG2 cell lysate was used to examine the expression of human MET. Lanes 1-5 represent MET monoclonal antibody, clone 4AT247 (Cat # MAB1147). Lane 6 represents auto-phosohorylated-MET in HepG2 cell line detected by anti-phospho-MET monaclonal antibody (Cat # MAB0115).