Ab183336

antibody from Aladdin Scientific

Targeting: MET DFNB97, HGFR, RCCP2

ELISA (Supportive data in Antibodypedia)

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

Ab183336

Provider

Aladdin Scientific

Product name

Telisotuzumab vedotin (anti-c-Met)

Antibody type

Recombinant

Description

Telisotuzumab vedotin (anti-c-Met) is an antibody-drug conjugate (ADCs) targeting c-Met. Telisotuzumab vedotin (anti-c-Met) consists of Monomethyl Auristatin E (MMAE), Telisotuzumab antibody and a cleavable mc-val-cit-PABC type linker. Telisotuzumab vedotin (anti-c-Met) can be used in cancer research.Purity>90% (SDS-PAGE&SEC)Endotoxin Level< 1.0EU/mg

Reactivity

Human

Vial size

100_g,10mg,1mg,5mg

Concentration

Lot by Lot

Storage

Store at -80_ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.

ELISA

Supportive validation

Submitted by

Aladdin Scientific (provider)

Main image

Experimental details

Telisotuzumab vedotin (anti-c-Met) (Ab183336) - ELISA Immobilized Human HGFR/c-MET protein (rp169642) at 1.0 μg/mL can bind Telisotuzumab vedotin (anti-c-Met) (Ab183336) with the EC50 of 298.4 ng/mL.​

Flow cytometry

Supportive validation

Submitted by

Aladdin Scientific (provider)

Main image

Experimental details

Telisotuzumab vedotin (anti-c-Met) (Ab183336) - Flow Cytometry Flow Cytometry analysis of Hela cells labelling c-Met (red) with Telisotuzumab vedotin (anti-c-Met) (Ab183336). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Supportive validation

Submitted by

Aladdin Scientific (provider)

Main image

Experimental details

Telisotuzumab vedotin (anti-c-Met) (Ab183336) - Flow Cytometry Flow Cytometry analysis of A549 cells labelling c-Met (red) with Telisotuzumab vedotin (anti-c-Met) (Ab183336). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.