Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 10861-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10861-1-AP, RRID:AB_2143843
- Product name
- MECP2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MECP2 antibody (Cat. #10861-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Asynchronous microexon splicing of LSD1 and PHF21A during neurodevelopment.
PDK1 promotes breast cancer progression by enhancing the stability and transcriptional activity of HIF-1α.
Comprehensive analysis reveals the prognostic and immunogenic characteristics of DNA methylation regulators in lung adenocarcinoma.
DNA methylation of promoter region inhibits galectin-1 expression in BMSCs of aged mice.
SIRT1 modifies DNA methylation linked to synaptic deficits induced by Pb in vitro and in vivo.
Inhibition of DNA methylation de-represses peroxisome proliferator-activated receptor-γ and attenuates pulmonary fibrosis.
A prelude to the proximity interaction mapping of CXXC5.
Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk.
MeCP2 is a microsatellite binding protein that protects CA repeats from nucleosome invasion.
Integration of transcriptome and proteome profiles in placenta accreta reveals trophoblast over-migration as the underlying pathogenesis.
Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi of adolescent mice.
MicroRNA-29a is a key regulon that regulates BRD4 and mitigates liver fibrosis in mice by inhibiting hepatic stellate cell activation.
Lentivirus‑mediated knockdown of MeCP2 inhibits the growth of colorectal cancer cells in vitro.
Specificity of antinuclear autoantibodies recognizing the dense fine speckled nuclear pattern: Preferential targeting of DFS70/LEDGFp75 over its interacting partner MeCP2.
The stress oncoprotein LEDGF/p75 interacts with the methyl CpG binding protein MeCP2 and influences its transcriptional activity.
Intrathecal 5-azacytidine inhibits global DNA methylation and methyl- CpG-binding protein 2 expression and alleviates neuropathic pain in rats following chronic constriction injury.
Nagai M, Porter RS, Hughes E, Saunders TL, Iwase S
bioRxiv : the preprint server for biology 2024 Mar 21;
bioRxiv : the preprint server for biology 2024 Mar 21;
PDK1 promotes breast cancer progression by enhancing the stability and transcriptional activity of HIF-1α.
Wei Y, Zhang D, Shi H, Qian H, Chen H, Zeng Q, Jin F, Ye Y, Ou Z, Guo M, Guo B, Chen T
Genes & diseases 2024 Jul;11(4):101041
Genes & diseases 2024 Jul;11(4):101041
Comprehensive analysis reveals the prognostic and immunogenic characteristics of DNA methylation regulators in lung adenocarcinoma.
Huang J, Huang C, Huang C, Xiang Z, Ni Y, Zeng J, Cai S
Respiratory research 2024 Feb 5;25(1):74
Respiratory research 2024 Feb 5;25(1):74
DNA methylation of promoter region inhibits galectin-1 expression in BMSCs of aged mice.
Tang L, Zhang YY, Liu WJ, Fu Q, Zhao J, Liu YB
American journal of physiology. Cell physiology 2024 Feb 1;326(2):C429-C441
American journal of physiology. Cell physiology 2024 Feb 1;326(2):C429-C441
SIRT1 modifies DNA methylation linked to synaptic deficits induced by Pb in vitro and in vivo.
Wang R, Yang M, Wu Y, Liu R, Liu M, Li Q, Su X, Xin Y, Huo W, Deng Q, Ba Y, Huang H
International journal of biological macromolecules 2022 Sep 30;217:219-228
International journal of biological macromolecules 2022 Sep 30;217:219-228
Inhibition of DNA methylation de-represses peroxisome proliferator-activated receptor-γ and attenuates pulmonary fibrosis.
Wei A, Gao Q, Chen F, Zhu X, Chen X, Zhang L, Su X, Dai J, Shi Y, Cao W
British journal of pharmacology 2022 Apr;179(7):1304-1318
British journal of pharmacology 2022 Apr;179(7):1304-1318
A prelude to the proximity interaction mapping of CXXC5.
Ayaz G, Turan G, Olgun ÇE, Kars G, Karakaya B, Yavuz K, Demiralay ÖD, Can T, Muyan M, Yaşar P
Scientific reports 2021 Sep 2;11(1):17587
Scientific reports 2021 Sep 2;11(1):17587
Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk.
Wang XH, Xu S, Zhou XY, Zhao R, Lin Y, Cao J, Zang WD, Tao H, Xu W, Li MQ, Zhao SM, Jin LP, Zhao JY
Nature communications 2021 Jun 8;12(1):3428
Nature communications 2021 Jun 8;12(1):3428
MeCP2 is a microsatellite binding protein that protects CA repeats from nucleosome invasion.
Ibrahim A, Papin C, Mohideen-Abdul K, Le Gras S, Stoll I, Bronner C, Dimitrov S, Klaholz BP, Hamiche A
Science (New York, N.Y.) 2021 Jun 25;372(6549)
Science (New York, N.Y.) 2021 Jun 25;372(6549)
Integration of transcriptome and proteome profiles in placenta accreta reveals trophoblast over-migration as the underlying pathogenesis.
Li N, Hou R, Liu C, Yang T, Qiao C, Wei J
Clinical proteomics 2021 Dec 29;18(1):31
Clinical proteomics 2021 Dec 29;18(1):31
Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi of adolescent mice.
Buck JM, O'Neill HC, Stitzel JA
Epigenetics & chromatin 2020 Mar 5;13(1):13
Epigenetics & chromatin 2020 Mar 5;13(1):13
MicroRNA-29a is a key regulon that regulates BRD4 and mitigates liver fibrosis in mice by inhibiting hepatic stellate cell activation.
Huang YH, Kuo HC, Yang YL, Wang FS
International journal of medical sciences 2019;16(2):212-220
International journal of medical sciences 2019;16(2):212-220
Lentivirus‑mediated knockdown of MeCP2 inhibits the growth of colorectal cancer cells in vitro.
Song N, Li K, Wang Y, Chen Z, Shi L
Molecular medicine reports 2016 Jan;13(1):860-6
Molecular medicine reports 2016 Jan;13(1):860-6
Specificity of antinuclear autoantibodies recognizing the dense fine speckled nuclear pattern: Preferential targeting of DFS70/LEDGFp75 over its interacting partner MeCP2.
Basu A, Woods-Burnham L, Ortiz G, Rios-Colon L, Figueroa J, Albesa R, Andrade LE, Mahler M, Casiano CA
Clinical immunology (Orlando, Fla.) 2015 Dec;161(2):241-50
Clinical immunology (Orlando, Fla.) 2015 Dec;161(2):241-50
The stress oncoprotein LEDGF/p75 interacts with the methyl CpG binding protein MeCP2 and influences its transcriptional activity.
Leoh LS, van Heertum B, De Rijck J, Filippova M, Rios-Colon L, Basu A, Martinez SR, Tungteakkhun SS, Filippov V, Christ F, De Leon M, Debyser Z, Casiano CA
Molecular cancer research : MCR 2012 Mar;10(3):378-91
Molecular cancer research : MCR 2012 Mar;10(3):378-91
Intrathecal 5-azacytidine inhibits global DNA methylation and methyl- CpG-binding protein 2 expression and alleviates neuropathic pain in rats following chronic constriction injury.
Wang Y, Liu C, Guo QL, Yan JQ, Zhu XY, Huang CS, Zou WY
Brain research 2011 Oct 18;1418:64-9
Brain research 2011 Oct 18;1418:64-9
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 10861-1-AP( MECP2 Antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MECP2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MECP2. This antibody recognizes human,mouse,rat antigen. The MECP2 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
