Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- NB600-1101 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB600-1101, RRID:AB_2235280
- Product name
- Rabbit Polyclonal MeCP2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. This detects methyl CpG binding protein 2 (MeCP2) from human, mouse and rat tissues and cells.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 50ug
- Concentration
- 1 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Modeling neurogenesis impairment in Down syndrome with induced pluripotent stem cells from Trisomy 21 amniotic fluid cells.
Genetic modifiers of MeCP2 function in Drosophila.
Quantitative localization of heterogeneous methyl-CpG-binding protein 2 (MeCP2) expression phenotypes in normal and Rett syndrome brain by laser scanning cytometry.
Quantitative localization of heterogeneous methyl-CpG-binding protein 2 (MeCP2) expression phenotypes in normal and Rett syndrome brain by laser scanning cytometry.
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription.
Lu HE, Yang YC, Chen SM, Su HL, Huang PC, Tsai MS, Wang TH, Tseng CP, Hwang SM
Experimental cell research 2013 Feb 15;319(4):498-505
Experimental cell research 2013 Feb 15;319(4):498-505
Genetic modifiers of MeCP2 function in Drosophila.
Cukier HN, Perez AM, Collins AL, Zhou Z, Zoghbi HY, Botas J
PLoS genetics 2008 Sep 5;4(9):e1000179
PLoS genetics 2008 Sep 5;4(9):e1000179
Quantitative localization of heterogeneous methyl-CpG-binding protein 2 (MeCP2) expression phenotypes in normal and Rett syndrome brain by laser scanning cytometry.
LaSalle JM, Goldstine J, Balmer D, Greco CM
Human molecular genetics 2001 Aug 15;10(17):1729-40
Human molecular genetics 2001 Aug 15;10(17):1729-40
Quantitative localization of heterogeneous methyl-CpG-binding protein 2 (MeCP2) expression phenotypes in normal and Rett syndrome brain by laser scanning cytometry.
LaSalle JM, Goldstine J, Balmer D, Greco CM
Human molecular genetics 2001 Aug 15;10(17):1729-40
Human molecular genetics 2001 Aug 15;10(17):1729-40
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription.
Jones PL, Veenstra GJ, Wade PA, Vermaak D, Kass SU, Landsberger N, Strouboulis J, Wolffe AP
Nature genetics 1998 Jun;19(2):187-91
Nature genetics 1998 Jun;19(2):187-91
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: MeCP2 Antibody [NB600-1101] - Analysis of HeLa cell extract.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MeCP2 Antibody [NB600-1101] - Staining in the nucleus of rat brain tissue (right) compared to a negative control without primary antibody (left).