10541-1-AP

antibody from Proteintech Group

Targeting: CALM3 PHKD

Provider product page for 10541-1-AP

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [26]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [2]

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Product number: 10541-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#10541-1-AP, RRID:AB_2069442
Product name: Calmodulin antibody
Antibody type: Polyclonal
Description: Calmodulin antibody (Cat. #10541-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB, ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

CALM3 protein structure - 10541-1-AP shown in red.

Submitted references Protein Modifications and Metabolic Alterations in the Rat Striatum Following Oil Mist Particulate Matter Exposure Revealed via Untargeted Metabolomics and Phosphoproteomics.

Nie H, Liu X, Shi Y, Liu H, Lai W, Li K, Tian L, Xi Z, Lin B
Toxics 2026 Mar 12;14(3)

Astragaloside IV alleviates post-traumatic cytotoxic edema via inhibition of AQP4 expression and subcellular localization.

Shen W, Jiang C, Liu X, Wang D, Li G, Hui Y, Ding Y, Li C, Shao B, Hou B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158096

Lycium barbarum polysaccharides enhance testicular spermatogenesis in d-galactose-induced aging rats via calcium signaling.

Ma W, Liu C, Pu J, Liu Z, Hu N, Yang L, Chen D, Li H, Ma H
Andrology 2026 Feb;14(2):496-515

PCP4 inhibits the progression of prostate cancer through Ca(2+)/CAMKK2/AMPK/AR pathway.

Jia W, Yu Z, Sun F, Liu P, Han B
Frontiers in immunology 2025;16:1616046

High matrix stiffness triggers testosterone decline in aging males by disrupting stem Leydig cell pool homeostasis.

Huang J, Sun L, Yin Y, Yang H, Zeng K, Huang P, Liang X, Wu J, Xiang AP, Wang J
Cell reports 2025 Sep 23;44(9):116207

MicroRNA-502-3p Modulates the GABA A Subunits, Synaptic Proteins, and Mitochondrial Morphology in Hippocampal Neurons.

Sharma B, Rodarte D, Goyal G, Rodriguez S, Kumar S
Molecular neurobiology 2025 Oct;62(10):13479-13499

Targeting NFAT2 for Reversing the P-gp-Mediated Multidrug Resistance to Paclitaxel by Manidipine.

Zhou J, Wang N, Lin YK, Li QL, Liu RM, Hu JQ, Zhou H, Lan H, Xie Y
Cancers 2025 Oct 10;17(20)

VDAC1-NF-κB/p65-mediated S100A16 contributes to myocardial ischemia/reperfusion injury by regulating oxidative stress and inflammatory response via calmodulin/CaMKK2/AMPK pathway.

Zi C, Ma X, Zheng M, Zhu Y
European journal of pharmacology 2025 Jan 15;987:177158

MicroRNA-502-3p modulates the GABA A subunits, synaptic proteins and mitochondrial morphology in hippocampal neurons.

Sharma B, Rodarte D, Goyal G, Rodriguez S, Kumar S
bioRxiv : the preprint server for biology 2025 Jan 13;

Enriched Environment Ameliorates Cerebral Ischemia-Reperfusion Injury via Dopamine-H(2)S Axis-Mediated Dual Mitophagy Activation.

Zhou B, Qin H, Yang P, Ren N, Sun L, Ding Z, He Z, Zhang S, Hua Z, Zheng Y, Li C, Kuang S, Zhu Y, Yu K
Antioxidants (Basel, Switzerland) 2025 Dec 30;15(1)

A note of caution for using calmodulin antibodies.

Munk M, Berchtold MW
Journal of immunological methods 2024 Nov;534:113772

Calmodulin Contributes to Lipolysis and Inflammatory Responses in Clinical Ketosis Cows through the TLR4/IKK/NF-κB Pathway.

Chang J, Wang Z, Hao Y, Song Y, Xia C
Animals : an open access journal from MDPI 2024 Jun 4;14(11)

Stalled translation by mitochondrial stress upregulates a CNOT4-ZNF598 ribosomal quality control pathway important for tissue homeostasis.

Geng J, Li S, Li Y, Wu Z, Bhurtel S, Rimal S, Khan D, Ohja R, Brandman O, Lu B
Nature communications 2024 Feb 22;15(1):1637

Water-insoluble dietary fiber from walnut relieves constipation through Limosilactobacillus reuteri-mediated serotonergic synapse and neuroactive ligand-receptor pathways.

Yang W, Gao X, Lin J, Liu L, Peng L, Sheng J, Xu K, Tian Y
International journal of biological macromolecules 2024 Dec;283(Pt 4):137931

Activated PRDM1-CREBBP contributes to preeclampsia by regulating apoptosis and invasion of the human trophoblast cells.

Zhang X, Sun L
iScience 2024 Dec 20;27(12):111484

Selectively targeting the AdipoR2-CaM-CaMKII-NOS3 axis by SCM-198 as a rapid-acting therapy for advanced acute liver failure.

Wang R, Chen Y, Han J, Ye H, Yang H, Li Q, He Y, Ma B, Zhang J, Ge Y, Wang Z, Sun B, Liu H, Cheng L, Wang Z, Lin G
Nature communications 2024 Dec 16;15(1):10690

Morphological and Functional Colonic Defects Caused by a Mutated Thyroid Hormone Receptor α.

Kim M, Kruhlak M, Hoffmann V, Zerfas P, Bishop K, Doolittle WKL, Edmondson EF, Zhu YJ, Cheng SY
Thyroid : official journal of the American Thyroid Association 2023 Feb;33(2):239-250

Periplocin suppresses the growth of colorectal cancer cells by triggering LGALS3 (galectin 3)-mediated lysophagy.

Wang K, Fu S, Dong L, Zhang D, Wang M, Wu X, Shen E, Luo L, Li C, Nice EC, Huang C, Zou B
Autophagy 2023 Dec;19(12):3132-3150

Label-Free Quantification Mass Spectrometry Identifies Protein Markers of Chemotherapy Response in High-Grade Serous Ovarian Cancer.

Arentz G, Mittal P, Klingler-Hoffmann M, Condina MR, Ricciardelli C, Lokman NA, Kaur G, Oehler MK, Hoffmann P
Cancers 2023 Apr 6;15(7)

Sphingosylphosphorylcholine ameliorates doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by reducing excessive mitophagy and mitochondrial dysfunction.

Zhou J, Lu Y, Li Z, Wang Z, Kong W, Zhao J
Toxicology and applied pharmacology 2022 Oct 1;452:116207

The NMDAR GluN1-1a C-terminus binds to CaM and regulates synaptic function.

Zhou L, Duan J
Biochemical and biophysical research communications 2021 Jan 1;534:323-329

CALM1 promotes progression and dampens chemosensitivity to EGFR inhibitor in esophageal squamous cell carcinoma.

Liu T, Han X, Zheng S, Liu Q, Tuerxun A, Zhang Q, Yang L, Lu X
Cancer cell international 2021 Feb 18;21(1):121

SLC22A14 is a mitochondrial riboflavin transporter required for sperm oxidative phosphorylation and male fertility.

Kuang W, Zhang J, Lan Z, Deepak RNVK, Liu C, Ma Z, Cheng L, Zhao X, Meng X, Wang W, Wang X, Xu L, Jiao Y, Luo Q, Meng Z, Kee K, Liu X, Deng H, Li W, Fan H, Chen L
Cell reports 2021 Apr 20;35(3):109025

PINK1 suppresses alpha-synuclein-induced neuronal injury: a novel mechanism in protein phosphatase 2A activation.

Yang W, Wang X, Liu J, Duan C, Gao G, Lu L, Yu S, Yang H
Oncotarget 2018 Jan 2;9(1):37-53

TRPC1 Deficiency Impairs the Endothelial Progenitor Cell Function via Inhibition of Calmodulin/eNOS Pathway.

Du LL, Shen Z, Li Z, Ye X, Wu M, Hong L, Zhao Y
Journal of cardiovascular translational research 2018 Aug;11(4):339-345

Alpha-synuclein overexpression increases phospho-protein phosphatase 2A levels via formation of calmodulin/Src complex.

Yang W, Wang X, Duan C, Lu L, Yang H
Neurochemistry international 2013 Sep;63(3):180-94

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: mouse brain tissue were subjected to SDS PAGE followed by western blot with 10541-1-AP(CALM3 antibody) at dilution of 1:500
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The CALM3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CALM3. This antibody recognizes human,mouse,rat antigen. The CALM3 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
Appendix: 10541-1-AP.pdf

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human breast cancer using 10541-1-AP(CALM3 antibody) at dilution of 1:50 (under 10x lens)
Sample type: tissue