CRADD
gene productRAIDD
This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Featured antibodies
 Sigma-Aldrich |
 WH0008738M1 |
0 references | Monoclonal |
EL
ICC
|
 Biorbyt |
orb74316 |
0 references | Polyclonal |
WB
EL
ICC
IHC
|
Antibodies
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Enhanced validation Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI