Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10222-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10222-1-AP, RRID:AB_2130292
- Product name
- Sam68 antibody
- Antibody type
- Polyclonal
- Description
- Sam68 antibody (Cat. #10222-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Perfluorooctane sulfonate (PFOS) induces apoptosis and autophagy by inhibition of PI3K/AKT/mTOR pathway in human granulosa cell line KGN.
CircMTA1 promotes glioblastoma angiogenesis by encoding MTA1-134aa.
HnRNPR strongly represses splicing of a critical exon associated with spinal muscular atrophy through binding to an exonic AU-rich element.
ZnO nanoparticles impair autophagic flux and cell viability through the TRIM16-NRF2-p62 pathway in inflammatory keratinocytes.
Shortening of the KHDRBS1 3'UTR by alternative cleavage and polyadenylation alters miRNA-mediated regulation and promotes gastric cancer progression.
Lipophagy-ICAM-1 pathway associated with fatty acid and oxygen deficiencies is involved in poor prognoses of ovarian clear cell carcinoma.
SAM68 promotes tumorigenesis in lung adenocarcinoma by regulating metabolic conversion via PKM alternative splicing.
LRRC4 mediates the formation of circular RNA CD44 to inhibitGBM cell proliferation.
Cold-induced RNA-binding protein (CIRBP) regulates the expression of Src-associated during mitosis of 68 kDa (Sam68) and extracellular signal-regulated kinases (ERK) during heat stress-induced testicular injury.
Regulatory T cells delay disease progression in Alzheimer-like pathology.
Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.
Gao M, Shen H, Li Q, Gu X, Jia T, Wang Y
Environmental pollution (Barking, Essex : 1987) 2024 Mar 1;344:123333
Environmental pollution (Barking, Essex : 1987) 2024 Mar 1;344:123333
CircMTA1 promotes glioblastoma angiogenesis by encoding MTA1-134aa.
Niu B, Wei D, Liu XY, Zhai B, Liu XB, Yao YL, Xue YX, Wang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23160
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23160
HnRNPR strongly represses splicing of a critical exon associated with spinal muscular atrophy through binding to an exonic AU-rich element.
Jiang T, Qu R, Liu X, Hou Y, Wang L, Hua Y
Journal of medical genetics 2023 Nov;60(11):1105-1115
Journal of medical genetics 2023 Nov;60(11):1105-1115
ZnO nanoparticles impair autophagic flux and cell viability through the TRIM16-NRF2-p62 pathway in inflammatory keratinocytes.
Wang M, Zheng H, Chen J, Tang Y, Feng M, Li L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114177
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114177
Shortening of the KHDRBS1 3'UTR by alternative cleavage and polyadenylation alters miRNA-mediated regulation and promotes gastric cancer progression.
Yu X, Kang W, Zhang J, Chen C, Liu Y
American journal of translational research 2022;14(9):6574-6585
American journal of translational research 2022;14(9):6574-6585
Lipophagy-ICAM-1 pathway associated with fatty acid and oxygen deficiencies is involved in poor prognoses of ovarian clear cell carcinoma.
Koizume S, Takahashi T, Nakamura Y, Yoshihara M, Ota Y, Sato S, Tadokoro H, Yokose T, Kato H, Miyagi E, Miyagi Y
British journal of cancer 2022 Aug;127(3):462-473
British journal of cancer 2022 Aug;127(3):462-473
SAM68 promotes tumorigenesis in lung adenocarcinoma by regulating metabolic conversion via PKM alternative splicing.
Zhu S, Chen W, Wang J, Qi L, Pan H, Feng Z, Tian D
Theranostics 2021;11(7):3359-3375
Theranostics 2021;11(7):3359-3375
LRRC4 mediates the formation of circular RNA CD44 to inhibitGBM cell proliferation.
Feng J, Ren X, Fu H, Li D, Chen X, Zu X, Liu Q, Wu M
Molecular therapy. Nucleic acids 2021 Dec 3;26:473-487
Molecular therapy. Nucleic acids 2021 Dec 3;26:473-487
Cold-induced RNA-binding protein (CIRBP) regulates the expression of Src-associated during mitosis of 68 kDa (Sam68) and extracellular signal-regulated kinases (ERK) during heat stress-induced testicular injury.
Xu C, Ke D, Zou L, Li N, Wang Y, Fan X, Zhu C, Xia W
Reproduction, fertility, and development 2020 Dec;32(18):1357-1364
Reproduction, fertility, and development 2020 Dec;32(18):1357-1364
Regulatory T cells delay disease progression in Alzheimer-like pathology.
Dansokho C, Ait Ahmed D, Aid S, Toly-Ndour C, Chaigneau T, Calle V, Cagnard N, Holzenberger M, Piaggio E, Aucouturier P, Dorothée G
Brain : a journal of neurology 2016 Apr;139(Pt 4):1237-51
Brain : a journal of neurology 2016 Apr;139(Pt 4):1237-51
Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.
Neumann M, Valori CF, Ansorge O, Kretzschmar HA, Munoz DG, Kusaka H, Yokota O, Ishihara K, Ang LC, Bilbao JM, Mackenzie IR
Acta neuropathologica 2012 Nov;124(5):705-16
Acta neuropathologica 2012 Nov;124(5):705-16
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10222-1-AP(KHDRBS1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using KHDRBS1 antibody 10222-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10222-1-AP(KHDRBS1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue