AFC-TAB-903

antibody from Creative Biolabs

Targeting: RTN4 ASY, KIAA0886, NOGO, NSP-CL

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Flow cytometry (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

AFC-TAB-903

Provider

Creative Biolabs

Product name

Afuco? Anti-RTN4 ADCC Recombinant Antibody (Ozanezumab), ADCC Enhanced

Antibody type

Monoclonal

Description

This product is an ADCC enhanced antibody produced by our Afuco? platform. Recombinant humanized (from mouse) antibody expressed in CHO binding to human Nogo-A. Ozanezumab is a monoclonal antibody designed for the treatment of ALS and multiple sclerosis. Ozanezumab targets a protein called Neurite Outgrowth Inhibitor (NOGO-A) or Reticulon 4. NOGO-A is a protein that in humans is encoded by the RTN4 gene that has been identified as an inhibitor of neurite outgrowth specific to the central nervous system. NOGO-A is found at higher than normal levels in persons with MND.

Reactivity

Human

Host

Human

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

Ozanezumab

Storage

Store at +4¡ãC short term (1-2 weeks). Aliquot and store at -20¡ãC long term. Avoid repeated freeze/thaw cycles.