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- References [15]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 10950-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- RTN4/NOGO antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RTN4/NOGO antibody (Cat. #10950-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification of EEF1A2 as a potential therapy target of osteosarcoma using novel compound 8e.
Mechanisms Promoting Tumor Progression and Angiogenesis in Retinoblastoma: OTX2 Enhances RTN4 Transcription.
Long-term fucoxanthin treatment prevents cognitive impairments and neuroinflammation via the inhibition of Nogo-A in APP/PS1 transgenic mice.
Rpl12 is a conserved ribophagy receptor.
Identification of Nogo-B as a potential therapeutic target of osteosarcoma via stereochemically selective covalent probes.
The assembly of RAB22A/TMEM33/RTN4 initiates a secretory ER-phagy pathway.
Unraveling the causal relationship and potential mechanisms between osteoarthritis and breast cancer: insights from mendelian randomization and bioinformatics analysis.
Super-resolution microscopy reveals focal organization of ER-associated Y-complexes in mitosis.
Deficiency of Perry syndrome-associated p150(Glued) in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities.
Nogo-B inhibition restricts ulcerative colitis via inhibiting p68/miR-155 signaling pathway.
SEC24A facilitates colocalization and Ca(2)(+) flux between the endoplasmic reticulum and mitochondria.
Tanshinone IIA Promotes Axonal Regeneration in Rats with Focal Cerebral Ischemia Through the Inhibition of Nogo-A/NgR1/RhoA/ROCKII/MLC Signaling.
Reticulon and CLIMP-63 regulate nanodomain organization of peripheral ER tubules.
Erythropoietin attenuates axonal injury after middle cerebral artery occlusion in mice.
Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B.
Xue J, Li M, Wang Y, Sun D, Hao S, Liu Z, Zhang W, Li L, Zhu T, Liu S
European journal of medicinal chemistry 2026 Jan 15;302(Pt 3):118355
European journal of medicinal chemistry 2026 Jan 15;302(Pt 3):118355
Mechanisms Promoting Tumor Progression and Angiogenesis in Retinoblastoma: OTX2 Enhances RTN4 Transcription.
Xi L, Li W, Deng B, Zhao F
The Tohoku journal of experimental medicine 2025 Oct 17;267(2):163-175
The Tohoku journal of experimental medicine 2025 Oct 17;267(2):163-175
Long-term fucoxanthin treatment prevents cognitive impairments and neuroinflammation via the inhibition of Nogo-A in APP/PS1 transgenic mice.
Jiang Y, Chen H, Xu J, Le J, Rong W, Zhu Z, Chen Y, Hu C, Cai J, Hong Y, Huang S, Zheng M, Zhang X, Zhou C, Zhang J, He S, Yan X, Cui W
Food & function 2025 May 19;16(10):3891-3903
Food & function 2025 May 19;16(10):3891-3903
Rpl12 is a conserved ribophagy receptor.
Chen Y, Hu J, Zhao P, Fang J, Kuang Y, Liu Z, Dong S, Yao W, Ding Y, Wang X, Pan Y, Wu J, Zhao J, Yang J, Xu Z, Liu X, Zhang Y, Wu C, Zhang L, Fan M, Feng S, Hong Z, Yan Z, Xia H, Tang K, Yang B, Liu W, Sun Q, Mei K, Zou W, Huang Y, Feng D, Yi C
Nature cell biology 2025 Mar;27(3):477-492
Nature cell biology 2025 Mar;27(3):477-492
Identification of Nogo-B as a potential therapeutic target of osteosarcoma via stereochemically selective covalent probes.
Xue J, Li M, Kang L, Wang M, Yin J, Sun D, Deng Y, Wei Q, Wong J, Zhu T, Liu S
Cell death & disease 2025 Jul 19;16(1):537
Cell death & disease 2025 Jul 19;16(1):537
The assembly of RAB22A/TMEM33/RTN4 initiates a secretory ER-phagy pathway.
Zheng X, Fang D, Shan H, Xiao B, Wei D, Ouyang Y, Huo L, Zhang Z, Wu Y, Zhang R, Kang T, Gao Y
Cell discovery 2025 Apr 29;11(1):41
Cell discovery 2025 Apr 29;11(1):41
Unraveling the causal relationship and potential mechanisms between osteoarthritis and breast cancer: insights from mendelian randomization and bioinformatics analysis.
Li K, Wang R
Discover oncology 2024 Dec 18;15(1):769
Discover oncology 2024 Dec 18;15(1):769
Super-resolution microscopy reveals focal organization of ER-associated Y-complexes in mitosis.
Gandhimathi R, Pinotsi D, Köhler M, Mansfeld J, Ashiono C, Kleele T, Pawar S, Kutay U
EMBO reports 2023 Sep 6;24(9):e56766
EMBO reports 2023 Sep 6;24(9):e56766
Deficiency of Perry syndrome-associated p150(Glued) in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities.
Yu J, Yang X, Zheng J, Sgobio C, Sun L, Cai H
NPJ Parkinson's disease 2023 Mar 7;9(1):35
NPJ Parkinson's disease 2023 Mar 7;9(1):35
Nogo-B inhibition restricts ulcerative colitis via inhibiting p68/miR-155 signaling pathway.
Zheng J, Wang S, Zhang T, Li H, Zhu M, Wei X, Ge Y, Yang X, Zhang S, Xu H, Duan Y, Liu L, Chen Y
International immunopharmacology 2023 Jul;120:110378
International immunopharmacology 2023 Jul;120:110378
SEC24A facilitates colocalization and Ca(2)(+) flux between the endoplasmic reticulum and mitochondria.
Chidawanyika T, Chakrabarti R, Beauchemin KS, Higgs HN, Supattapone S
Journal of cell science 2021 Mar 26;134(6)
Journal of cell science 2021 Mar 26;134(6)
Tanshinone IIA Promotes Axonal Regeneration in Rats with Focal Cerebral Ischemia Through the Inhibition of Nogo-A/NgR1/RhoA/ROCKII/MLC Signaling.
Wang J, Ni G, Liu Y, Han Y, Jia L, Wang Y
Drug design, development and therapy 2020;14:2775-2787
Drug design, development and therapy 2020;14:2775-2787
Reticulon and CLIMP-63 regulate nanodomain organization of peripheral ER tubules.
Gao G, Zhu C, Liu E, Nabi IR
PLoS biology 2019 Aug;17(8):e3000355
PLoS biology 2019 Aug;17(8):e3000355
Erythropoietin attenuates axonal injury after middle cerebral artery occlusion in mice.
Wang R, Zhao H, Li J, Duan Y, Fan Z, Tao Z, Ju F, Yan F, Luo Y
Neurological research 2017 Jun;39(6):545-551
Neurological research 2017 Jun;39(6):545-551
Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B.
Lennemann NJ, Coyne CB
Autophagy 2017 Feb;13(2):322-332
Autophagy 2017 Feb;13(2):322-332
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A375 cells were subjected to SDS PAGE followed by western blot with 10950-1-AP(RTN4 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RTN4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RTN4. This antibody recognizes human antigen. The RTN4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
