RA0641

antibody from Oursmab

Targeting: RTN4 ASY, KIAA0886, NOGO, NSP-CL

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0641

Provider

Oursmab

Product name

Atinumab (Biosimilar Reference Antibody) (RTN4)

Antibody type

Monoclonal

Description

Atinumab is a human monoclonal antibody engineered to specifically target and neutralize the Reticulon-4 (RTN-4) protein, also known as Nogo-A. RTN-4 is a critical inhibitor of neuronal regeneration and axonal growth within the central nervous system (CNS). By binding to RTN-4, Atinumab effectively blocks its inhibitory action on neurons. This neutralization is intended to promote axonal sprouting and neuronal plasticity, facilitating nerve repair and functional recovery after CNS injuries. Atinumab has been investigated as a potential therapeutic agent for debilitating conditions involving nerve damage, such as spinal cord injury (SCI), stroke, and multiple sclerosis.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.