Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- AF1559 - Provider product page
- Provider
- R&D Systems
- Product name
- Human Notch-3 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects human Notch-3 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse Notch-3 is observed and less than 5% cross-reactivity with recombinant human (rh) Notch-1 and rhNotch-2 is observed.
- Reactivity
- Human
- Host
- Sheep
- Conjugate
- Unconjugated
- Antigen sequence
Q9UM47
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression.
Notch3 activation modulates cell growth behaviour and cross-talk to Wnt/TCF signalling pathway.
Franciosa G, Diluvio G, Gaudio FD, Giuli MV, Palermo R, Grazioli P, Campese AF, Talora C, Bellavia D, D'Amati G, Besharat ZM, Nicoletti C, Siebel CW, Choy L, Rustighi A, Sal GD, Screpanti I, Checquolo S
Oncogene 2016 Sep 8;35(36):4741-51
Oncogene 2016 Sep 8;35(36):4741-51
Notch3 activation modulates cell growth behaviour and cross-talk to Wnt/TCF signalling pathway.
Wang T, Holt CM, Xu C, Ridley C, P O Jones R, Baron M, Trump D
Cellular signalling 2007 Dec;19(12):2458-67
Cellular signalling 2007 Dec;19(12):2458-67
No comments: Submit comment
No validations: Submit validation data