Antibody data
- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [2]
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- ABIN393589 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 415-509) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 415-509
- Isotype
- IgG
- Antibody clone number
- 2C7
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk.
Human BAHD1 promotes heterochromatic gene silencing.
Methyl-CpG binding domain 1 gene polymorphisms and lung cancer risk in a Chinese population.
Silencing of MBD1 and MeCP2 in prostate-cancer-derived PC3 cells produces differential gene expression profiles and cellular phenotypes.
Proteomic analysis of differential proteins in pancreatic carcinomas: Effects of MBD1 knock-down by stable RNA interference.
Specific binding of the methyl binding domain protein 2 at the BRCA1-NBR2 locus.
Crowther-Swanepoel D, Broderick P, Di Bernardo MC, Dobbins SE, Torres M, Mansouri M, Ruiz-Ponte C, Enjuanes A, Rosenquist R, Carracedo A, Jurlander J, Campo E, Juliusson G, Montserrat E, Smedby KE, Dyer MJ, Matutes E, Dearden C, Sunter NJ, Hall AG, Mainou-Fowler T, Jackson GH, Summerfield G, Harris RJ, Pettitt AR, Allsup DJ, Bailey JR, Pratt G, Pepper C, Fegan C, Parker A, Oscier D, Allan JM, Catovsky D, Houlston RS
Nature genetics 2010 Feb;42(2):132-6
Nature genetics 2010 Feb;42(2):132-6
Human BAHD1 promotes heterochromatic gene silencing.
Bierne H, Tham TN, Batsche E, Dumay A, Leguillou M, Kernéis-Golsteyn S, Regnault B, Seeler JS, Muchardt C, Feunteun J, Cossart P
Proceedings of the National Academy of Sciences of the United States of America 2009 Aug 18;106(33):13826-31
Proceedings of the National Academy of Sciences of the United States of America 2009 Aug 18;106(33):13826-31
Methyl-CpG binding domain 1 gene polymorphisms and lung cancer risk in a Chinese population.
Liu H, Jin G, Wang H, Wu W, Liu Y, Qian J, Fan W, Ma H, Miao R, Hu Z, Sun W, Wang Y, Jin L, Wei Q, Shen H, Huang W, Lu D
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2008 Sep;13(6):607-17
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2008 Sep;13(6):607-17
Silencing of MBD1 and MeCP2 in prostate-cancer-derived PC3 cells produces differential gene expression profiles and cellular phenotypes.
Yaqinuddin A, Abbas F, Naqvi SZ, Bashir MU, Qazi R, Qureshi SA
Bioscience reports 2008 Dec;28(6):319-26
Bioscience reports 2008 Dec;28(6):319-26
Proteomic analysis of differential proteins in pancreatic carcinomas: Effects of MBD1 knock-down by stable RNA interference.
Liu C, Chen Y, Yu X, Jin C, Xu J, Long J, Ni Q, Fu D, Jin H, Bai C
BMC cancer 2008 Apr 29;8:121
BMC cancer 2008 Apr 29;8:121
Specific binding of the methyl binding domain protein 2 at the BRCA1-NBR2 locus.
Auriol E, Billard LM, Magdinier F, Dante R
Nucleic acids research 2005;33(13):4243-54
Nucleic acids research 2005;33(13):4243-54
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