15820-1-AP

antibody from Proteintech Group

Targeting: HMMR CD168, RHAMM

Provider product page for 15820-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [23]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]

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Product number: 15820-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#15820-1-AP, RRID:AB_2295342
Product name: HMMR-Specific antibody
Antibody type: Polyclonal
Description: KD/KO validated HMMR-Specific antibody (Cat. #15820-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

HMMR protein structure - 15820-1-AP shown in red.

Submitted references HMMR is a novel prognostic marker and a potential therapeutic target for colon cancer.

Fang L, Lin J, Huang D, Li J, Cui W, Deng M, Zhang Y
Cellular signalling 2026 Feb;138:112249

N(6)-methyladenosine Reader IGF2BP2-modified HMMR Promotes Non-small Cell Lung Cancer Metastasis via Interaction with MAP4K4.

Zhang J, Zhang M, Qiu A, Li C, Chen Q, Li J, Zeng Y, Zhu J, Huang JA, Zhang X, Liu Z
International journal of biological sciences 2025;21(4):1391-1409

Prognostic value and experimental validation of atherosclerosis-derived pathogenic genes in colorectal cancer.

Li Y, Wei J, Xu Y, Wu Z, He S, Zhu Y, Ni W, Zhang D, Xu H, Zhang C, Zhou A, Shen T, Li J
Frontiers in oncology 2025;15:1728087

Opioid System Antagonism Alters Vascular Proteome and Collagen Deposition in ApoE(-/-) Mice.

Jaskuła K, Nawrocka A, Poznański P, Stachowicz A, Łazarczyk M, Sacharczuk M, Skiba DS
Cells 2025 Oct 8;14(19)

Hyaluronan-mediated motility receptor regulating the Wnt/β-catenin signaling resulting in hepatocellular carcinoma by inhibiting the phosphorylation activity of GSK-3β.

Zhang Y, Zhang Z, Yan Z, He M, Wang X
European journal of medical research 2025 Oct 30;30(1):1042

The mechanisms of MTOCs maturation in human and mouse oocytes.

Gu H, Wu L, Yin M, Du X, Fu J, Xu F, Ye Z, Zhang X, Jing H, Luo Y, Li W, Sun X, He L, Kuang Y, Lyu Q, Wu T, Wang L, Sang Q
Science bulletin 2025 Oct 15;70(19):3202-3214

Investigating Liquid-Liquid Phase Separation in Lung Adenocarcinoma to Improve Prognostic Accuracy and Treatment Efficacy.

Song Z, Li Y, Zhang P, Wei K, Zhu M, Wang Y, Li Z, Chen L, Zheng J
Journal of cellular and molecular medicine 2025 Aug;29(16):e70807

Identification of glycolysis-related molecular subtypes and prognostic model in intrahepatic cholangiocarcinoma.

Wang Y, Wang P, Liu H, Feng H, Cao M, Zhang Z, Rao K, Fan J, Fu X, Sun Y
Discover oncology 2025 Aug 18;16(1):1577

FIGNL1 Promotes Hepatocellular Carcinoma Formation via Remodeling ECM-receptor Interaction Pathway Mediated by HMMR.

Wang J, Sun L, Liu Y, Zhang Y
Current gene therapy 2024;24(3):249-263

FOXM1 mediates methotrexate resistance in osteosarcoma cells by promoting autophagy.

Wang L, Zhai D, Tang L, Zhang H, Wang X, Ma N, Zhang X, Cheng M, Shen R
Acta biochimica et biophysica Sinica 2024 Jul 31;56(9):1289-1299

Comprehensive Analysis Identifies Hyaluronan Mediated Motility Receptor and Cell Division Cycle 25C as Potential Prognostic Biomarkers in Head and Neck Squamous Cell Carcinoma.

Zhang H, Xu Y, Han H, Ye X, Cheng L, Shen Y, Wan X
Cancer control : journal of the Moffitt Cancer Center 2024 Jan-Dec;31:10732748241287904

Identification of potential biomarkers for hepatocellular carcinoma based on machine learning and bioinformatics analysis.

Chen C, Peng R, Jin S, Tang Y, Liu H, Tu D, Su B, Wang S, Jiang G, Cao J, Zhang C, Bai D
Discover oncology 2024 Dec 18;15(1):808

Single-cell transcriptomic analysis identifies a highly replicating Cd168(+) skeletal stem/progenitor cell population in mouse long bones.

Hao RC, Li ZL, Wang FY, Tang J, Li PL, Yin BF, Li XT, Han MY, Mao N, Liu B, Ding L, Zhu H
Journal of genetics and genomics = Yi chuan xue bao 2023 Sep;50(9):702-712

Integrative multi-omics analysis unveils stemness-associated molecular subtypes in prostate cancer and pan-cancer: prognostic and therapeutic significance.

Zheng K, Hai Y, Xi Y, Zhang Y, Liu Z, Chen W, Hu X, Zou X, Hao J
Journal of translational medicine 2023 Nov 7;21(1):789

Effects of Therapeutic Platelet-Rich Plasma on Overactive Bladder via Modulating Hyaluronan Synthesis in Ovariectomized Rat.

Lu JH, Chueh KS, Juan TJ, Mao JW, Lin RJ, Lee YC, Shen MC, Sun TW, Lin HY, Juan YS
International journal of molecular sciences 2023 May 4;24(9)

HMMR promotes prostate cancer proliferation and metastasis via AURKA/mTORC2/E2F1 positive feedback loop.

Guo K, Liu C, Shi J, Lai C, Gao Z, Luo J, Li Z, Tang Z, Li K, Xu K
Cell death discovery 2023 Feb 7;9(1):48

Hmmr Acts as a Key Regulator in the ADSCs Proliferation and Mitosis.

Zhang X, Huang D, Li K, Han C, Li H, Li C, Liu L
Stem cell reviews and reports 2023 Aug;19(6):1937-1953

The mechanism of acentrosomal spindle assembly in human oocytes.

Wu T, Dong J, Fu J, Kuang Y, Chen B, Gu H, Luo Y, Gu R, Zhang M, Li W, Dong X, Sun X, Sang Q, Wang L
Science (New York, N.Y.) 2022 Nov 18;378(6621):eabq7361

Development and validation of a combined metabolism and immune prognostic model in lung adenocarcinoma.

Shi Y, Dai S, Lei Y
Journal of thoracic disease 2022 Dec;14(12):4983-4997

Oleate acid-stimulated HMMR expression by CEBPα is associated with nonalcoholic steatohepatitis and hepatocellular carcinoma.

Zhang D, Liu J, Xie T, Jiang Q, Ding L, Zhu J, Ye Q
International journal of biological sciences 2020;16(15):2812-2827

Fam83d modulates MAP kinase and AKT signaling and is induced during neurogenic skeletal muscle atrophy.

Cooper LM, Hanson A, Kavanagh JA, Waddell DS
Cellular signalling 2020 Jun;70:109576

A pH-sensitive luminal His-cluster promotes interaction of PAM with V-ATPase along the secretory and endocytic pathways of peptidergic cells.

Rao VK, Zavala G, Deb Roy A, Mains RE, Eipper BA
Journal of cellular physiology 2019 Jun;234(6):8683-8697

Tracing haematopoietic stem cell formation at single-cell resolution.

Zhou F, Li X, Wang W, Zhu P, Zhou J, He W, Ding M, Xiong F, Zheng X, Li Z, Ni Y, Mu X, Wen L, Cheng T, Lan Y, Yuan W, Tang F, Liu B
Nature 2016 May 26;533(7604):487-92

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: mouse brain tissue were subjected to SDS PAGE followed by western blot with 15820-1-AP(HMMR-Specific antibody) at dilution of 1:800
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of HepG2 cells, using HMMR antibody 15820-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Sample type: cell line