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- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 66172-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- MSH6 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated MSH6 antibody (Cat. #66172-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2E10B2
- Vial size
- 20ul, 150ul
Submitted references DNA methylation mediates the immunosuppressive tumour microenvironment in metastatic endometrial clear cell carcinoma.
The mechanism of RGS5 regulating gastric cancer mismatch repair protein.
TMPRSS2 is a tumor suppressor and its downregulation promotes antitumor immunity and immunotherapy response in lung adenocarcinoma.
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Inhibition of KIF20A enhances the immunotherapeutic effect of hepatocellular carcinoma by enhancing c-Myc ubiquitination.
CJ(2): A Novel Potent Platinum(IV) Prodrug Enhances Chemo-Immunotherapy by Facilitating PD-L1 Degradation in the Cytoplasm and Cytomembrane.
Remodeling Chondroitin-6-Sulfate-Mediated Immune Exclusion Enhances Anti-PD-1 Response in Colorectal Cancer with Microsatellite Stability.
Sebaceous adenoma occurring within an intracranial dermoid cyst.
Clinicopathological and survival characteristic of mismatch repair status in ovarian clear cell carcinoma.
Mismatch repair status as a beneficial predictor of fluorouracil-based adjuvant chemotherapy for pancreatic cancer.
HDAC10 expression is associated with DNA mismatch repair gene and is a predictor of good prognosis in colon carcinoma.
Jia H, Chen Y, Ma G, Xu S, Zhang X, Chang L, Yang P, Xiao Y, Xia X, Zhang S, Tang H, Mou Y, Zhang L, Wang H, Bai J, Yi X, Xing X
EBioMedicine 2025 Oct;120:105954
EBioMedicine 2025 Oct;120:105954
The mechanism of RGS5 regulating gastric cancer mismatch repair protein.
Yang Z, Zhang R, Liu J, Tian S, Zhang H, Zeng L, Zhang Y, Gao L, Wang M, Shan W, Liu J
Molecular carcinogenesis 2024 Sep;63(9):1750-1767
Molecular carcinogenesis 2024 Sep;63(9):1750-1767
TMPRSS2 is a tumor suppressor and its downregulation promotes antitumor immunity and immunotherapy response in lung adenocarcinoma.
Liu Z, Lu Q, Zhang Z, Feng Q, Wang X
Respiratory research 2024 Jun 11;25(1):238
Respiratory research 2024 Jun 11;25(1):238
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Jiang Y, Wang Y, Chen G, Sun F, Wu Q, Huang Q, Zeng D, Qiu W, Wang J, Yao Z, Liang B, Li S, Wu J, Huang N, Wang Y, Chen J, Zhai X, Huang L, Xu B, Yamamoto M, Tsukamoto T, Nomura S, Liao W, Shi M
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Inhibition of KIF20A enhances the immunotherapeutic effect of hepatocellular carcinoma by enhancing c-Myc ubiquitination.
Chen S, Zhao L, Liu J, Han P, Jiang W, Liu Y, Hou J, Wang F, Li J
Cancer letters 2024 Aug 28;598:217105
Cancer letters 2024 Aug 28;598:217105
CJ(2): A Novel Potent Platinum(IV) Prodrug Enhances Chemo-Immunotherapy by Facilitating PD-L1 Degradation in the Cytoplasm and Cytomembrane.
Fan R, Deng A, Qi B, Zhang S, Sang R, Luo L, Gou J, Liu Y, Lin R, Zhao M, Liu Y, Yang L, Cheng M, Wei G
Journal of medicinal chemistry 2023 Jan 12;66(1):875-889
Journal of medicinal chemistry 2023 Jan 12;66(1):875-889
Remodeling Chondroitin-6-Sulfate-Mediated Immune Exclusion Enhances Anti-PD-1 Response in Colorectal Cancer with Microsatellite Stability.
Wu Q, Huang Q, Jiang Y, Sun F, Liang B, Wang J, Hu X, Sun M, Ma Z, Shi Y, Liang Y, Tan Y, Zeng D, Yao F, Xu X, Yao Z, Li S, Rong X, Huang N, Sun L, Liao W, Shi M
Cancer immunology research 2022 Feb;10(2):182-199
Cancer immunology research 2022 Feb;10(2):182-199
Sebaceous adenoma occurring within an intracranial dermoid cyst.
Minamisaka T, Imura J, Shiraishi K, Takagi K, Tomia T, Tanaka S, Noguchi A, Akai T, Noguchi K, Kuroda S
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Aug;42(4):289-294
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Aug;42(4):289-294
Clinicopathological and survival characteristic of mismatch repair status in ovarian clear cell carcinoma.
Zhu J, Ke G, Bi R, Wu X
Journal of surgical oncology 2020 Sep;122(3):538-546
Journal of surgical oncology 2020 Sep;122(3):538-546
Mismatch repair status as a beneficial predictor of fluorouracil-based adjuvant chemotherapy for pancreatic cancer.
Liang D, Shi S, Liang C, Meng Q, Zhang B, Ni Q, Xu J, Yu X
Surgery 2018 May;163(5):1080-1089
Surgery 2018 May;163(5):1080-1089
HDAC10 expression is associated with DNA mismatch repair gene and is a predictor of good prognosis in colon carcinoma.
Tao X, Yan Y, Lu L, Chen B
Oncology letters 2017 Oct;14(4):4923-4929
Oncology letters 2017 Oct;14(4):4923-4929
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 66172-1-Ig( MSH6 Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MSH6 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human MSH6. This antibody recognizes human antigen. The MSH6 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
