FNab05375

antibody from FineTest Biotech

Targeting: MSH6 GTBP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

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Validation data

Product number: FNab05375 - Provider product page
Provider: FineTest Biotech
Product name: MSH6 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
Reactivity: Human, Mouse, Simian
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: mutS homolog 6
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)

MSH6 protein structure - FNab05375 shown in red.