Antibody data
- Antibody Data
- Antigen structure
- References [40]
- Comments [0]
- Validations [0]
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- Product number
- 29329-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- GPX1 antibody
- Antibody type
- Polyclonal
- Description
- GPX1 antibody (Cat. #29329-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Microenvironment-targeted strontium delivery system reshapes redox homeostasis to halt degenerative cascades in intervertebral discs.
Polypeptide Nanomicrospheres Delivering Dexmedetomidine Mitigate Intestinal Ischemia/Reperfusion Injury by Regulating Autophagy and Inflammation.
An intrabody targeting PHD2 protects mice against acetaminophen-induced liver injury by attenuating ferroptosis.
A GPX1-OSBPL8 axis mediates noncanonical in vivo ferroptosis and cancer growth suppression.
Mechanistic insights into fluoride-induced reproductive toxicity in female ovine animals: Mitochondrial dysfunction and ER stress-driven apoptosis in ovine granulosa cells.
Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility.
Air pollution decreases postsynaptic PSD-95 and NMDA receptor subunits in synaptosomes from mouse cerebral cortex.
Optimized clonal isolation and immortalization of Rett syndrome patient fibroblasts for in vitro modeling of MECP2 mutations.
Identification of novel biomarkers for cognitive function via an integrative analysis.
Xingnao jianshen prescription reduces mitochondrial cristae breakage by protecting GPX1 from oxidation against cerebral ischemia-reperfusion injury.
SERCA2 dysfunction accelerates angiotensin II-induced aortic aneurysm and atherosclerosis by induction of oxidative stress in aortic smooth muscle cells.
Ginsenoside Rb1 combined with Lycium barbarum polysaccharide alleviate the Tripterygium wilfordii polyglycoside-induced oligoasthenozoospermia in mice by inhibiting ZnT3-mediated oxidative stress response.
Tripartite Motif-Containing Protein 65 Promotes Proliferation and Inhibits Ferroptosis in Prostate Cancer via Enhancing NKD Inhibitor of WNT Signaling Pathway 2 Ubiquitination.
Mesenchymal stromal/stem cell spheroid-derived extracellular vesicles advance the therapeutic efficacy of 3D-printed vascularized artificial liver lobules in liver failure treatment.
Salvia miltiorrhiza extract ameliorated ovarian damage induced by cyclophosphamide in mice by multidimensional mechanisms.
Oxidative Stress and Epithelial-Mesenchymal Transition: The Impact of Ubiquitin C-terminal Hydrolase L1 in Cigarette Smoke-Induced COPD.
Xuebijing inhibits alveolar macrophage M1 polarization by regulating ROS-mediated NLRP3 inflammasome signaling.
Phosphoglycerate kinase 1 contributes to diabetic kidney disease through enzyme-dependent and independent manners.
Plant-derived hydrogel and photosynthetic nano-units for myocardial infarction therapy.
The Antioxidant Effect of Selenium Is Enhanced by Cortisol Through Nrf2 Pathway in Bovine Endometrial Epithelial Cells.
Iron(III)-salophene catalyzes redox cycles that induce phospholipid peroxidation and deplete cancer cells of ferroptosis-protecting cofactors.
MMP9 drives ferroptosis by regulating GPX4 and iron signaling.
LFHP-1c improves cognitive function after TBI in mice by reducing oxidative stress through the PGAM5-NRF2-KEAP1 ternary complex.
Glycyrrhizin Protects Submandibular Gland Against Radiation Damage by Enhancing Antioxidant Defense and Preserving Mitochondrial Homeostasis.
Arginine with leucine drives reactive oxygen species-mediated integrin α5β1 expression and promotes implantation in mouse blastocysts.
Treadmill exercise can regulate the redox balance in the livers of APP/PS1 mice and reduce LPS accumulation in their brains through the gut-liver-kupffer cell axis.
Effects of high-dose selenium-enriched Saccharomyces cerevisiae on growth performance, antioxidant status, tissue fat content and selenium concentration, and selenoenzyme mRNA expression in chicks.
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice.
Helicobacter Pylori-Enhanced hnRNPA2B1 Coordinates with PABPC1 to Promote Non-m(6)A Translation and Gastric Cancer Progression.
WDR23 mediates NRF2 proteostasis and cytoprotective capacity in the hippocampus.
Allicin promotes functional recovery in ischemic stroke via glutathione peroxidase-1 activation of Src-Akt-Erk.
WDR23 mediates NRF2 proteostasis and cytoprotective capacity in the hippocampus.
MitoQ ameliorates PM(2.5)-induced pulmonary fibrosis through regulating the mitochondria DNA homeostasis.
Effects of canagliflozin on myocardial microvascular density, oxidative stress, and proteomic profile(☆).
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
Polygonatum cyrtonema Hua Polysaccharides Protect BV2 Microglia Relief Oxidative Stress and Ferroptosis by Regulating NRF2/HO-1 Pathway.
CircRNA Samd4 induces cardiac repair after myocardial infarction by blocking mitochondria-derived ROS output.
Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes.
Adrenomedullin Improves Cardiac Remodeling and Function in Obese Rats with Hypertension.
Antioxidant Effects of DPP-4 Inhibitors in Early Stages of Experimental Diabetic Retinopathy.
Cheng H, A C, Shu Z, Zhao H, Wang L, Huang C, Li W, Fang X, Wu H, Bao X, Fang Z
Journal of controlled release : official journal of the Controlled Release Society 2026 Jan 10;389:114449
Journal of controlled release : official journal of the Controlled Release Society 2026 Jan 10;389:114449
Polypeptide Nanomicrospheres Delivering Dexmedetomidine Mitigate Intestinal Ischemia/Reperfusion Injury by Regulating Autophagy and Inflammation.
Liu Z, Hu Q, Chen Q, Wu Q, Liang S, Nie J, Fan C, Zhang Q, Zhang X
Antioxidants & redox signaling 2026 Feb;44(4-6):213-235
Antioxidants & redox signaling 2026 Feb;44(4-6):213-235
An intrabody targeting PHD2 protects mice against acetaminophen-induced liver injury by attenuating ferroptosis.
Ren Z, Wang Y, Cheng C, Zhang Y, Liu Y, Wei Y, Liu Z, Zhang J, Shi Z, Yu J, Hu W, Ye J, Wang J, Qiu S, Li G
Free radical biology & medicine 2026 Feb 1;243:260-275
Free radical biology & medicine 2026 Feb 1;243:260-275
A GPX1-OSBPL8 axis mediates noncanonical in vivo ferroptosis and cancer growth suppression.
Xia Z, Yang X, Samovich SN, Tyurina YY, Tyurin VA, Kon N, Zhang J, Jiang X, Stockwell BR, Jin J, Bayir H, Kagan VE, Gu W
Cell 2026 Apr 2;189(7):1957-1974.e17
Cell 2026 Apr 2;189(7):1957-1974.e17
Mechanistic insights into fluoride-induced reproductive toxicity in female ovine animals: Mitochondrial dysfunction and ER stress-driven apoptosis in ovine granulosa cells.
Ma T, Jiang D, Liu W, Li Z, Gao K, Zhang Y
Ecotoxicology and environmental safety 2025 Sep 15;303:118830
Ecotoxicology and environmental safety 2025 Sep 15;303:118830
Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility.
Yabaji SM, Zhernovkov V, Araveti PB, Lata S, Rukhlenko OS, Abdullatif SA, Vanvalkenburg A, Alekseyev YO, Ma Q, Dayama G, Lau NC, Johnson WE, Bishai WR, Crossland NA, Campbell JD, Kholodenko BN, Gimelbrant AA, Kobzik L, Kramnik I
eLife 2025 Oct 2;14
eLife 2025 Oct 2;14
Air pollution decreases postsynaptic PSD-95 and NMDA receptor subunits in synaptosomes from mouse cerebral cortex.
Godoy-Lugo JA, Hicks D, Durra S, Massey ER, Shkirkova K, Sauri AI, Kerstiens E, Chen S, Zhao L, Sioutas C, Mack WJ, Finch CE, Thorwald MA
Environmental pollution (Barking, Essex : 1987) 2025 Oct 15;383:126845
Environmental pollution (Barking, Essex : 1987) 2025 Oct 15;383:126845
Optimized clonal isolation and immortalization of Rett syndrome patient fibroblasts for in vitro modeling of MECP2 mutations.
Sarne V, Huber A, Beribisky AV, Hengstschläger M, Laccone F, Steinkellner H
Scientific reports 2025 Oct 13;15(1):35696
Scientific reports 2025 Oct 13;15(1):35696
Identification of novel biomarkers for cognitive function via an integrative analysis.
Mao R, Zhao S, Chen J, Wang L, Zheng K, Li B
Journal of Alzheimer's disease : JAD 2025 Nov;108(2):931-947
Journal of Alzheimer's disease : JAD 2025 Nov;108(2):931-947
Xingnao jianshen prescription reduces mitochondrial cristae breakage by protecting GPX1 from oxidation against cerebral ischemia-reperfusion injury.
Wang X, Tao K, Sun L, Ren D, Xie S, Zhang K, Li X, Zhao D, Yang Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157369
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157369
SERCA2 dysfunction accelerates angiotensin II-induced aortic aneurysm and atherosclerosis by induction of oxidative stress in aortic smooth muscle cells.
Wang L, Song J, Yang Z, Zhang H, Wang Y, Liu J, Wang S, Shi J, Tong X
Journal of molecular and cellular cardiology 2025 Mar;200:68-81
Journal of molecular and cellular cardiology 2025 Mar;200:68-81
Ginsenoside Rb1 combined with Lycium barbarum polysaccharide alleviate the Tripterygium wilfordii polyglycoside-induced oligoasthenozoospermia in mice by inhibiting ZnT3-mediated oxidative stress response.
Li X, Ding J, Wang J, He J, Sheng W
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Jun;89:127646
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Jun;89:127646
Tripartite Motif-Containing Protein 65 Promotes Proliferation and Inhibits Ferroptosis in Prostate Cancer via Enhancing NKD Inhibitor of WNT Signaling Pathway 2 Ubiquitination.
Wang C, Jiang H
Rejuvenation research 2025 Jun;28(3):113-124
Rejuvenation research 2025 Jun;28(3):113-124
Mesenchymal stromal/stem cell spheroid-derived extracellular vesicles advance the therapeutic efficacy of 3D-printed vascularized artificial liver lobules in liver failure treatment.
Zhang J, Chen X, Chai Y, Jin Y, Li F, Zhuo C, Xu Y, Wang H, Ju E, Lao YH, Xie X, Li M, Tao Y
Bioactive materials 2025 Jul;49:121-139
Bioactive materials 2025 Jul;49:121-139
Salvia miltiorrhiza extract ameliorated ovarian damage induced by cyclophosphamide in mice by multidimensional mechanisms.
Zhou L, Bai HL, Wang LJ, Xiao J, Liu Y, Ai JH, Li KZ, Ma D, Han Y
Journal of ovarian research 2025 Jul 11;18(1):149
Journal of ovarian research 2025 Jul 11;18(1):149
Oxidative Stress and Epithelial-Mesenchymal Transition: The Impact of Ubiquitin C-terminal Hydrolase L1 in Cigarette Smoke-Induced COPD.
Yang JJ, Liu HJ, Wang YX, Wang LP, Gu JJ, Gao JY, Ren KQ, Min LF
Lung 2025 Feb 25;203(1):36
Lung 2025 Feb 25;203(1):36
Xuebijing inhibits alveolar macrophage M1 polarization by regulating ROS-mediated NLRP3 inflammasome signaling.
Chen X, Zhang F, Zhou Z, Jiang D, Wen L
In vitro cellular & developmental biology. Animal 2025 Aug;61(7):789-800
In vitro cellular & developmental biology. Animal 2025 Aug;61(7):789-800
Phosphoglycerate kinase 1 contributes to diabetic kidney disease through enzyme-dependent and independent manners.
Sun HJ, Lu QB, Liu SJ, Fu X, Yu CL, Su JB, Meng XY, Guo X, Shao X, Li JH, Sun QY, Zhu XX, Shan JJ, Zhou W
Cell reports. Medicine 2025 Aug 19;6(8):102241
Cell reports. Medicine 2025 Aug 19;6(8):102241
Plant-derived hydrogel and photosynthetic nano-units for myocardial infarction therapy.
Lv Y, Zhu D, Li J, Li Y, Lu C, Bi J, Huang K, Hu S, Liu S, Yan N, Cheng K, Wang J
Nature communications 2025 Aug 18;16(1):7678
Nature communications 2025 Aug 18;16(1):7678
The Antioxidant Effect of Selenium Is Enhanced by Cortisol Through Nrf2 Pathway in Bovine Endometrial Epithelial Cells.
Cui L, Zhong J, Duan J, Li W, Mao P, Dong J, Liu K, Guo L, Wang H, Li J
Animals : an open access journal from MDPI 2025 Apr 8;15(8)
Animals : an open access journal from MDPI 2025 Apr 8;15(8)
Iron(III)-salophene catalyzes redox cycles that induce phospholipid peroxidation and deplete cancer cells of ferroptosis-protecting cofactors.
Su F, Descher H, Bui-Hoang M, Stuppner H, Skvortsova I, Rad EB, Ascher C, Weiss A, Rao Z, Hohloch S, Koeberle SC, Gust R, Koeberle A
Redox biology 2024 Sep;75:103257
Redox biology 2024 Sep;75:103257
MMP9 drives ferroptosis by regulating GPX4 and iron signaling.
Gawargi FI, Mishra PK
iScience 2024 Sep 20;27(9):110622
iScience 2024 Sep 20;27(9):110622
LFHP-1c improves cognitive function after TBI in mice by reducing oxidative stress through the PGAM5-NRF2-KEAP1 ternary complex.
Shao W, Wang JJ, Niu ZH, Zhang K, Wang S, Wang YH, Tang YH, Wang CC, Hou SQ, Zhou DR, Zhang C, Lin N
Heliyon 2024 Sep 15;10(17):e36820
Heliyon 2024 Sep 15;10(17):e36820
Glycyrrhizin Protects Submandibular Gland Against Radiation Damage by Enhancing Antioxidant Defense and Preserving Mitochondrial Homeostasis.
Zhou XR, Wang XY, Sun YM, Zhang C, Liu KJ, Zhang FY, Xiang B
Antioxidants & redox signaling 2024 Oct;41(10-12):723-743
Antioxidants & redox signaling 2024 Oct;41(10-12):723-743
Arginine with leucine drives reactive oxygen species-mediated integrin α5β1 expression and promotes implantation in mouse blastocysts.
Nakazato M, Matsuzaki M, Okai D, Takeuchi E, Seki M, Takeuchi M, Fukui E, Matsumoto H
PNAS nexus 2024 Mar;3(3):pgae114
PNAS nexus 2024 Mar;3(3):pgae114
Treadmill exercise can regulate the redox balance in the livers of APP/PS1 mice and reduce LPS accumulation in their brains through the gut-liver-kupffer cell axis.
Yuan S, Wang Y, Yang J, Tang Y, Wu W, Meng X, Jian Y, Lei Y, Liu Y, Tang C, Zhao Z, Zhao F, Liu W
Aging 2024 Jan 29;16(2):1374-1389
Aging 2024 Jan 29;16(2):1374-1389
Effects of high-dose selenium-enriched Saccharomyces cerevisiae on growth performance, antioxidant status, tissue fat content and selenium concentration, and selenoenzyme mRNA expression in chicks.
Gao S, Qiu H, Chen F, Yang G, Hou L, Dong J, Dong W
Poultry science 2024 Dec;103(12):104312
Poultry science 2024 Dec;103(12):104312
Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice.
O'Shea TM, Ao Y, Wang S, Ren Y, Cheng AL, Kawaguchi R, Shi Z, Swarup V, Sofroniew MV
Nature neuroscience 2024 Aug;27(8):1505-1521
Nature neuroscience 2024 Aug;27(8):1505-1521
Helicobacter Pylori-Enhanced hnRNPA2B1 Coordinates with PABPC1 to Promote Non-m(6)A Translation and Gastric Cancer Progression.
Yu Y, Yang YL, Chen XY, Chen ZY, Zhu JS, Zhang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(30):e2309712
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(30):e2309712
WDR23 mediates NRF2 proteostasis and cytoprotective capacity in the hippocampus.
Liu J, Duangjan C, Irwin RW, Curran SP
Mechanisms of ageing and development 2024 Apr;218:111914
Mechanisms of ageing and development 2024 Apr;218:111914
Allicin promotes functional recovery in ischemic stroke via glutathione peroxidase-1 activation of Src-Akt-Erk.
Zhuang F, Shi X, Qiao S, Liu B, Wang Z, Huo H, Liang F, Shen L, Zhu L, He B, Wang H
Cell death discovery 2023 Sep 6;9(1):335
Cell death discovery 2023 Sep 6;9(1):335
WDR23 mediates NRF2 proteostasis and cytoprotective capacity in the hippocampus.
Liu J, Duangjan C, Irwin RW, Curran SP
bioRxiv : the preprint server for biology 2023 Oct 11;
bioRxiv : the preprint server for biology 2023 Oct 11;
MitoQ ameliorates PM(2.5)-induced pulmonary fibrosis through regulating the mitochondria DNA homeostasis.
Li Y, Du Z, Li T, Ren X, Yu Y, Duan J, Sun Z
Chemosphere 2023 Jul;330:138745
Chemosphere 2023 Jul;330:138745
Effects of canagliflozin on myocardial microvascular density, oxidative stress, and proteomic profile(☆).
Sabe SA, Xu CM, Sabra M, Harris DD, Broadwin M, Bellam KG, Banerjee D, Usheva A, Ruhul Abid M, Sellke FW
Journal of molecular and cellular cardiology plus 2023 Dec;6
Journal of molecular and cellular cardiology plus 2023 Dec;6
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13661-13675
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13661-13675
Polygonatum cyrtonema Hua Polysaccharides Protect BV2 Microglia Relief Oxidative Stress and Ferroptosis by Regulating NRF2/HO-1 Pathway.
Li J, Wang X, Zhou R, Cheng F, Tang X, Lao J, Xu L, He W, Wan D, Zeng H, Zhang S
Molecules (Basel, Switzerland) 2022 Oct 20;27(20)
Molecules (Basel, Switzerland) 2022 Oct 20;27(20)
CircRNA Samd4 induces cardiac repair after myocardial infarction by blocking mitochondria-derived ROS output.
Zheng H, Huang S, Wei G, Sun Y, Li C, Si X, Chen Y, Tang Z, Li X, Chen Y, Liao W, Liao Y, Bin J
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Nov 2;30(11):3477-3498
Molecular therapy : the journal of the American Society of Gene Therapy 2022 Nov 2;30(11):3477-3498
Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes.
Dai HB, Wang HY, Wang FZ, Qian P, Gao Q, Zhou H, Zhou YB
Acta diabetologica 2022 May;59(5):661-673
Acta diabetologica 2022 May;59(5):661-673
Adrenomedullin Improves Cardiac Remodeling and Function in Obese Rats with Hypertension.
Qian P, Wang Q, Wang FZ, Dai HB, Wang HY, Gao Q, Zhou H, Zhou YB
Pharmaceuticals (Basel, Switzerland) 2022 Jun 6;15(6)
Pharmaceuticals (Basel, Switzerland) 2022 Jun 6;15(6)
Antioxidant Effects of DPP-4 Inhibitors in Early Stages of Experimental Diabetic Retinopathy.
Ramos H, Bogdanov P, Huerta J, Deàs-Just A, Hernández C, Simó R
Antioxidants (Basel, Switzerland) 2022 Jul 21;11(7)
Antioxidants (Basel, Switzerland) 2022 Jul 21;11(7)
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