ABIN1673413

antibody from antibodies-online

Targeting: SMARCB1 BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1673413

Provider

antibodies-online

Product name

anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1) (C-Term) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence at the C-terminal of human SMARCB1, identical to the related rat and mouse sequences.Immunogen affinity purified.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

100 μg

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Germline SMARCB1 mutation predisposes to multiple meningiomas and schwannomas with preferential location of cranial meningiomas at the falx cerebri.

van den Munckhof P, Christiaans I, Kenter SB, Baas F, Hulsebos TJ
Neurogenetics 2012 Feb;13(1):1-7

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The human SNF5/INI1 protein facilitates the function of the growth arrest and DNA damage-inducible protein (GADD34) and modulates GADD34-bound protein phosphatase-1 activity.

Wu DY, Tkachuck DC, Roberson RS, Schubach WH
The Journal of biological chemistry 2002 Aug 2;277(31):27706-15

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Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer.

Versteege I, Sévenet N, Lange J, Rousseau-Merck MF, Ambros P, Handgretinger R, Aurias A, Delattre O
Nature 1998 Jul 9;394(6689):203-6