CABT-B1712
antibody from Creative Diagnostics
Targeting: SMARCB1
BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1
Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B1712 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-SMARCB1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1), also known as BRG1-associated factor 47 (BAF47) or Integrase interactor 1 protein or SNF5 homolog (hSNF5), and encoded by the gene name SMARCB1 or BAF47, is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein has also been shown to bind to and enhance the DNA joining activity of HIV-1 integrase. It has been found to be a tumor suppressor, and the loss of SMARCB1 has been associated with malignant rhabdoid tumors. Tumor cells of synovial sarcoma seem to have a post transcriptional regulatory mechanism for SMARCB1.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 _g
- Concentration
- Please refer to lot specific datasheet.
- Storage
- Stable for 1 year at 2-8°C from date of receipt.
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