Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 13388-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13388-1-AP, RRID:AB_2248725
- Product name
- IHH antibody
- Antibody type
- Polyclonal
- Description
- IHH antibody (Cat. #13388-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references High matrix stiffness triggers testosterone decline in aging males by disrupting stem Leydig cell pool homeostasis.
G-protein-coupled estrogen receptor-1 facilitates chondrocyte proliferation in pubertal epiphyseal growth plate via PTHrP/Ihh regulation.
In situ implantation of type II collagen-based double-layer scaffolds for Articular Osteochondral Regeneration comprising hyaline cartilage and vascularized subchondral bones.
Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice.
Distraction force promotes the osteogenic differentiation of Gli1(+) cells in facial sutures via primary cilia-mediated Hedgehog signaling pathway.
Primary cilia support cartilage regeneration after injury.
Hepatocyte-targeted siTAZ therapy lowers liver fibrosis in NASH diet-fed chimeric mice with hepatocyte-humanized livers.
Hedgehog Signalling Contributes to Trauma-Induced Tendon Heterotopic Ossification and Regulates Osteogenesis through Antioxidant Pathway in Tendon-Derived Stem Cells.
DDB1 promotes the proliferation and hypertrophy of chondrocytes during mouse skeleton development.
TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling.
Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.
Inhibition of Ihh Reverses Temporomandibular Joint Osteoarthritis via a PTH1R Signaling Dependent Mechanism.
Intra-articular Delivery of Antago-miR-483-5p Inhibits Osteoarthritis by Modulating Matrilin 3 and Tissue Inhibitor of Metalloproteinase 2.
mTORC1 activation downregulates FGFR3 and PTH/PTHrP receptor in articular chondrocytes to initiate osteoarthritis.
Huang J, Sun L, Yin Y, Yang H, Zeng K, Huang P, Liang X, Wu J, Xiang AP, Wang J
Cell reports 2025 Sep 23;44(9):116207
Cell reports 2025 Sep 23;44(9):116207
G-protein-coupled estrogen receptor-1 facilitates chondrocyte proliferation in pubertal epiphyseal growth plate via PTHrP/Ihh regulation.
Chou YS, Lin SY, Chuang SC, Shih PY, Chen CH, Ho ML, Chang JK
Bone & joint research 2025 Jul 1;14(7):589-600
Bone & joint research 2025 Jul 1;14(7):589-600
In situ implantation of type II collagen-based double-layer scaffolds for Articular Osteochondral Regeneration comprising hyaline cartilage and vascularized subchondral bones.
Zhang Z, Huang Y, Hu X, Mu Y, Zhou H, Ma L, Liu B, Yao H, Jiang X, Wang DA
Bioactive materials 2025 Aug;50:364-381
Bioactive materials 2025 Aug;50:364-381
Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice.
Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X
Frontiers in cell and developmental biology 2024;12:1376814
Frontiers in cell and developmental biology 2024;12:1376814
Distraction force promotes the osteogenic differentiation of Gli1(+) cells in facial sutures via primary cilia-mediated Hedgehog signaling pathway.
Jin M, An Y, Wang Z, Wang G, Lin Z, Ding P, Lu E, Zhao Z, Bi H
Stem cell research & therapy 2024 Jul 6;15(1):198
Stem cell research & therapy 2024 Jul 6;15(1):198
Primary cilia support cartilage regeneration after injury.
Tao D, Zhang L, Ding Y, Tang N, Xu X, Li G, Niu P, Yue R, Wang X, Shen Y, Sun Y
International journal of oral science 2023 Jun 2;15(1):22
International journal of oral science 2023 Jun 2;15(1):22
Hepatocyte-targeted siTAZ therapy lowers liver fibrosis in NASH diet-fed chimeric mice with hepatocyte-humanized livers.
Wang X, Moore MP, Shi H, Miyata Y, Donnelly SK, Radiloff DR, Tabas I
Molecular therapy. Methods & clinical development 2023 Dec 14;31:101165
Molecular therapy. Methods & clinical development 2023 Dec 14;31:101165
Hedgehog Signalling Contributes to Trauma-Induced Tendon Heterotopic Ossification and Regulates Osteogenesis through Antioxidant Pathway in Tendon-Derived Stem Cells.
Li G, Deng Y, Li K, Liu Y, Wang L, Wu Z, Chen C, Zhang K, Yu B
Antioxidants (Basel, Switzerland) 2022 Nov 16;11(11)
Antioxidants (Basel, Switzerland) 2022 Nov 16;11(11)
DDB1 promotes the proliferation and hypertrophy of chondrocytes during mouse skeleton development.
Zhao L, Wang X, Pomlok K, Liao H, Yang G, Yang X, Chen YG
Developmental biology 2020 Sep 15;465(2):100-107
Developmental biology 2020 Sep 15;465(2):100-107
TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling.
Zhu R, Gires O, Zhu L, Liu J, Li J, Yang H, Ju G, Huang J, Ge W, Chen Y, Lu Z, Wang H
Nature communications 2019 Jun 28;10(1):2863
Nature communications 2019 Jun 28;10(1):2863
Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.
Oichi T, Taniguchi Y, Soma K, Oshima Y, Yano F, Mori Y, Chijimatsu R, Kim-Kaneyama JR, Tanaka S, Saito T
Cellular and molecular life sciences : CMLS 2019 Dec;76(23):4795-4809
Cellular and molecular life sciences : CMLS 2019 Dec;76(23):4795-4809
Inhibition of Ihh Reverses Temporomandibular Joint Osteoarthritis via a PTH1R Signaling Dependent Mechanism.
Yang H, Zhang M, Liu Q, Zhang H, Zhang J, Lu L, Xie M, Chen D, Wang M
International journal of molecular sciences 2019 Aug 3;20(15)
International journal of molecular sciences 2019 Aug 3;20(15)
Intra-articular Delivery of Antago-miR-483-5p Inhibits Osteoarthritis by Modulating Matrilin 3 and Tissue Inhibitor of Metalloproteinase 2.
Wang H, Zhang H, Sun Q, Wang Y, Yang J, Yang J, Zhang T, Luo S, Wang L, Jiang Y, Zeng C, Cai D, Bai X
Molecular therapy : the journal of the American Society of Gene Therapy 2017 Mar 1;25(3):715-727
Molecular therapy : the journal of the American Society of Gene Therapy 2017 Mar 1;25(3):715-727
mTORC1 activation downregulates FGFR3 and PTH/PTHrP receptor in articular chondrocytes to initiate osteoarthritis.
Zhang H, Wang H, Zeng C, Yan B, Ouyang J, Liu X, Sun Q, Zhao C, Fang H, Pan J, Xie D, Yang J, Zhang T, Bai X, Cai D
Osteoarthritis and cartilage 2017 Jun;25(6):952-963
Osteoarthritis and cartilage 2017 Jun;25(6):952-963
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human kidney tissue were subjected to SDS PAGE followed by western blot with 13388-1-AP(IHH antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human stomach cancer using 13388-1-AP(IHH antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The IHH antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human IHH. This antibody recognizes human,mouse,rat antigen. The IHH antibody has been validated for the following applications: ELISA, WB, IHC analysis.