BS6633

antibody from Bioworld Technology, Inc
Targeting: IGFBP5
Provider product page for BS6633
Western blot
Immunohistochemistry

Antibody data

Product number
BS6633 - Provider product page
Provider
Bioworld Technology, Inc
Product name
IGFBP5 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human IGFBP5.
Description
Seven IGFBPs have thus far been described, each differing in their tissue distribution, half-lives and modulation of IGF interactions with their receptors. For instance, IGFBP1 is negatively regulated by insulin production. The IGFBP1 gene is expressed at a high level during fetal liver development and in response to nutritional changes and diabetes. It has been suggested that IGFBP2 functions as chaperone, escorting IGFs to their target tissues. It is expressed in several human tissues including fetal eye and fetal brain. IGFBP3 is the most abundant IGFBP and is complexed with roughly 80% of the serum IGFs. Both IGFBP3 and IGFBP4 are released by dermal fibroblasts in response to incision injury. IGFBP5 is secreted by myoblasts and may play a key role in muscle differentiation.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
IGFBP5 protein structure - BS6633 shown in red.