MB0092

antibody from Bioworld Technology, Inc
Targeting: IKZF1 hIk-1, Hs.54452, IKAROS, LyF-1, PPP1R92, ZNFN1A1
Provider product page for MB0092
Western blot
Immunoprecipitation

Antibody data

Product number
MB0092 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Ikaros (C terminus) monoclonal antibody
Antibody type
Monoclonal
Antigen
Synthetic peptide, corresponding to the C-terminus of Human Ikaros.
Description
Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs).
Reactivity
Human
Host
Mouse
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
IKZF1 protein structure - MB0092 shown in red.