Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB17281 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB17281, RRID:AB_10646203
- Product name
- PLCB3 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PLCB3.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Mesangial cell-reduced Ca2+ signaling in high glucose is due to inactivation of phospholipase C-beta3 by protein kinase C.
Phosphorylation of a distinct structural form of phosphatidylinositol transfer protein alpha at Ser166 by protein kinase C disrupts receptor-mediated phospholipase C signaling by inhibiting delivery of phosphatidylinositol to membranes.
Frecker H, Munk S, Wang H, Whiteside C
American journal of physiology. Renal physiology 2005 Nov;289(5):F1078-87
American journal of physiology. Renal physiology 2005 Nov;289(5):F1078-87
Phosphorylation of a distinct structural form of phosphatidylinositol transfer protein alpha at Ser166 by protein kinase C disrupts receptor-mediated phospholipase C signaling by inhibiting delivery of phosphatidylinositol to membranes.
Morgan CP, Skippen A, Segui B, Ball A, Allen-Baume V, Larijani B, Murray-Rust J, McDonald N, Sapkota G, Morrice N, Cockcroft S
The Journal of biological chemistry 2004 Nov 5;279(45):47159-71
The Journal of biological chemistry 2004 Nov 5;279(45):47159-71
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from HeLa cells treated with PMA (125 ng/ml, 30 min), using PLCB3 polyclonal antibody (Cat # PAB17281).Peptide "+" means "with peptide blocking".
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human brain tissue using PLCB3 polyclonal antibody (Cat # PAB17281).Peptide "+" means "with peptide blocking".
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)