12037-1-AP

antibody from Proteintech Group

Targeting: DVL2

Provider product page for 12037-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [26]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]

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Product number: 12037-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#12037-1-AP, RRID:AB_2093330
Product name: DVL2 antibody
Antibody type: Polyclonal
Description: KD/KO validated DVL2 antibody (Cat. #12037-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

DVL2 protein structure - 12037-1-AP shown in red.

Submitted references Maternal fiber-rich diet promotes early-life intestinal development in offspring through milk-derived extracellular vesicles carrying miR-146a-5p.

Lu D, Liu Y, Kang L, Zhang X, Hu J, Ye H, Huang B, Wu Y, Zhao J, Dai Z, Wang J, Han D
Journal of nanobiotechnology 2024 Feb 16;22(1):65

Suppression of Wnt/β-catenin Signaling in PDAC via METTL16-mediated N6-methyladenosine Modification of DVL2.

Yu L, Lu J, Xie N, Fang L, Chen S, Wu Y, Wang X, Li B
Journal of Cancer 2023;14(16):2964-2977

Aquaporin 9 is involved in CRC metastasis through DVL2-dependent Wnt/β-catenin signaling activation.

Liu Y, Gao Q, Feng X, Chen G, Jiang X, Chen D, Yang Z
Gastroenterology report 2023;11:goad033

Polycystin-2-dependent transcriptome reveals early response of autosomal dominant polycystic kidney disease.

Jung HJ, Dixon EE, Coleman R, Watnick T, Reiter JF, Outeda P, Cebotaru V, Woodward OM, Welling PA
Physiological genomics 2023 Nov 1;55(11):565-577

Neuroprotective effects of oxymatrine on hypoxic-ischemic brain damage in neonatal rats by activating the Wnt/β-catenin pathway.

Lan XB, Ni YS, Liu N, Wei W, Liu Y, Yang JM, Ma L, Bai R, Zhang J, Yu JQ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Mar;159:114266

Electroacupuncture promotes neurogenesis in the dentate gyrus and improves pattern separation in an early Alzheimer's disease mouse model.

Ding Y, Li L, Wang S, Cao Y, Yang M, Dai Y, Lin H, Li J, Liu Y, Wang Z, Liu W, Tao J
Biological research 2023 Dec 2;56(1):65

Regulation of the WNT-CTNNB1 signaling pathway by severe fever with thrombocytopenia syndrome virus in a cap-snatching manner.

Jiang X-M, Xin Q-L, Liu K, Peng X-F, Han S, Zhang L-Y, Liu W, Xiao G-F, Li H, Zhang L-K
mBio 2023 Dec 19;14(6):e0168823

CAMK2N1 has a cancer-suppressive function in colorectal carcinoma via effects on the Wnt/β-catenin pathway.

Zhang X, Tian L, Li Z, Liu R, Yu J, Liu B
Biochemical and biophysical research communications 2022 Oct 20;626:220-228

SiNiSan alleviates liver injury by promoting hepatic stem cell differentiation via Wnt/β-catenin signaling pathway.

Xu W, Du X, Li J, Zhang Z, Ma X, Luo D, Xiao M, Sun Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:153969

Vangl2 participates in the primary ciliary assembly under low fluid shear stress in hUVECs.

Sheng X, Gao S, Sheng Y, Xie X, Wang J, He Y
Cell and tissue research 2022 Jan;387(1):95-109

High expression of serine and arginine-rich splicing factor 9 (SRSF9) is associated with hepatocellular carcinoma progression and a poor prognosis.

Zhang G, Liu B, Shang H, Wu G, Wu D, Wang L, Li S, Wang Z, Wang S, Yuan J
BMC medical genomics 2022 Aug 15;15(1):180

EPA and DHA differentially coordinate the crosstalk between host and gut microbiota and block DSS-induced colitis in mice by a reinforced colonic mucus barrier.

Fang J, Zhang Z, Cheng Y, Yang H, Zhang H, Xue Z, Lu S, Dong Y, Song C, Zhang X, Zhou Y
Food & function 2022 Apr 20;13(8):4399-4420

Non-Canonical Wnt Signaling Regulates Cochlear Outgrowth and Planar Cell Polarity via Gsk3β Inhibition.

Landin Malt A, Clancy S, Hwang D, Liu A, Smith C, Smith M, Hatley M, Clemens C, Lu X
Frontiers in cell and developmental biology 2021;9:649830

MYH9 is crucial for stem cell-like properties in non-small cell lung cancer by activating mTOR signaling.

Chen M, Sun LX, Yu L, Liu J, Sun LC, Yang ZH, Shu X, Ran YL
Cell death discovery 2021 Oct 11;7(1):282

Differential effects of EPA and DHA on DSS-induced colitis in mice and possible mechanisms involved.

Zhang Z, Xue Z, Yang H, Zhao F, Liu C, Chen J, Lu S, Zou Z, Zhou Y, Zhang X
Food & function 2021 Mar 1;12(4):1803-1817

Cyclin G2 upregulation impairs migration, invasion, and network formation through RNF123/Dvl2/JNK signaling in the trophoblast cell line HTR8/SVneo, a possible role in preeclampsia.

Sun M, Gao J, Meng T, Liu S, Chen H, Liu Q, Xing X, Zhao C, Luo Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Feb;35(2):e21169

PWP1 Promotes the Malignant Phenotypes of Lung Cancer Cells by Interacting with DVL2 and Merlin.

Wei L, Li P, Luo Y, Zhang M, Yan T, Yang Y, Han Y, Liu S, Wang E
OncoTargets and therapy 2020;13:10025-10037

Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling.

Landin Malt A, Hogan AK, Smith CD, Madani MS, Lu X
The Journal of cell biology 2020 Oct 5;219(10)

YAP triggers the Wnt/β-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury.

Deng F, Peng L, Li Z, Tan G, Liang E, Chen S, Zhao X, Zhi F
Cell death & disease 2018 Feb 2;9(2):153

Characterization of potential TRPP2 regulating proteins in early Xenopus embryos.

Futel M, Le Bouffant R, Buisson I, Umbhauer M, Riou JF
Journal of cellular biochemistry 2018 Dec;119(12):10338-10350

Baicalin increases hair follicle development by increasing canonical Wnt/β‑catenin signaling and activating dermal papillar cells in mice.

Xing F, Yi WJ, Miao F, Su MY, Lei TC
International journal of molecular medicine 2018 Apr;41(4):2079-2085

Cyclic compression stimulates osteoblast differentiation via activation of the Wnt/β-catenin signaling pathway.

Chen X, Guo J, Yuan Y, Sun Z, Chen B, Tong X, Zhang L, Shen C, Zou J
Molecular medicine reports 2017 May;15(5):2890-2896

The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning.

Rauschenberger V, Bernkopf DB, Krenn S, Jalal K, Heller J, Behrens J, Gentzel M, Schambony A
Development (Cambridge, England) 2017 Jun 15;144(12):2234-2247

Protective effect of autophagy in neural ischemia and hypoxia: Negative regulation of the Wnt/β-catenin pathway.

Shi ZY, Deng JX, Fu S, Wang L, Wang Q, Liu B, Li YQ, Deng JB
International journal of molecular medicine 2017 Dec;40(6):1699-1708

Paternal nicotine exposure defines different behavior in subsequent generation via hyper-methylation of mmu-miR-15b.

Dai J, Wang Z, Xu W, Zhang M, Zhu Z, Zhao X, Zhang D, Nie D, Wang L, Qiao Z
Scientific reports 2017 Aug 4;7(1):7286

Distinct functionality of dishevelled isoforms on Ca2+/calmodulin-dependent protein kinase 2 (CamKII) in Xenopus gastrulation.

Gentzel M, Schille C, Rauschenberger V, Schambony A
Molecular biology of the cell 2015 Mar 1;26(5):966-77

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 12037-1-AP( DVL2 Antibody) at dilution of 1:1000
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The DVL2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DVL2. This antibody recognizes human,mouse,rat antigen. The DVL2 antibody has been validated for the following applications: ELISA, WB, IF analysis.
Appendix: 12037-1-AP.pdf

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