Antibody data
- Antibody Data
- Antigen structure
- References [44]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10774-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10774-1-AP, RRID:AB_2185497
- Product name
- SFTPC antibody
- Antibody type
- Polyclonal
- Description
- SFTPC antibody (Cat. #10774-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Senegenin Attenuates Pulmonary Fibrosis by Inhibiting Oxidative-Stress-Induced Epithelial Cell Senescence through Activation of the Sirt1/Pgc-1α Signaling Pathway.
YAP/TAZ activation mediates PQ-induced lung fibrosis by sustaining senescent pulmonary epithelial cells.
Tenascin-C modulates alveolarization in bronchopulmonary dysplasia.
Protein lysine acetylation played an important role in NH(3)-induced AEC2 damage and pulmonary fibrosis in piglets.
Role of Sox9 in BPD and its effects on the Wnt/β-catenin pathway and AEC-II differentiation.
Human milk exosome-derived circDNAJB6 improves bronchopulmonary dysplasia model by promoting DNAJB6 gene transcription.
Pasteurella multocida activates apoptosis via the FAK-AKT-FOXO1 axis to cause pulmonary integrity loss, bacteremia, and eventually a cytokine storm.
Evolutionary genetics of pulmonary anatomical adaptations in deep-diving cetaceans.
DEC1 is involved in circadian rhythm disruption-exacerbated pulmonary fibrosis.
Downregulation of a potential therapeutic target NPAS2, regulated by p53, alleviates pulmonary fibrosis by inhibiting epithelial-mesenchymal transition via suppressing HES1.
Tat-P combined with GAPR1 releases Beclin1 to promote autophagy and improve Bronchopulmonary dysplasia model.
CircABPD1 alleviates oxidative lung injury of bronchopulmonary dysplasia through regulating miR-330-3p/HIF1α axis.
MICALL2 participates in the regulation of epithelial-mesenchymal transition in alveolar epithelial cells - Potential roles in pulmonary fibrosis.
GBP2 upregulated in LPS-stimulated macrophages-derived exosomes accelerates septic lung injury by activating epithelial cell NLRP3 signaling.
Necroptosis signaling and NLRP3 inflammasome cross-talking in epithelium facilitate Pseudomonas aeruginosa mediated lung injury.
Deletion of LCMR1 in alveolar type II cells induces lethal impairment of lung structure and function in adult mice.
Attenuation of PM(2.5)-induced alveolar epithelial cells and lung injury through regulation of mitochondrial fission and fusion.
Inhaled pulmonary surfactant biomimetic liposomes for reversing idiopathic pulmonary fibrosis through synergistic therapeutic strategy.
Impact of Salt Intake and Renin-Angiotensin-Aldosterone System Blockade on Lung Severe Acute Respiratory Syndrome Coronavirus 2 Host Factors.
D-tagatose protects against oleic acid-induced acute respiratory distress syndrome in rats by activating PTEN/PI3K/AKT pathway.
A New Homotetramer Hemoglobin in the Pulmonary Surfactant of Plateau Zokors (Myospalax Baileyi).
Claudin-18 expression under hyperoxia in neonatal lungs of bronchopulmonary dysplasia model rats.
A homotetrameric hemoglobin expressed in alveolar epithelial cells increases blood oxygenation in high-altitude plateau pika (Ochotona curzoniae).
Kub3 Deficiency Causes Aberrant Late Embryonic Lung Development in Mice by the FGF Signaling Pathway.
HAO1-mediated oxalate metabolism promotes lung pre-metastatic niche formation by inducing neutrophil extracellular traps.
Human breast milk-derived exosomes through inhibiting AT II cell apoptosis to prevent bronchopulmonary dysplasia in rat lung.
A SCID mouse-human lung xenograft model of SARS-CoV-2 infection.
TSSK4 upregulation in alveolar epithelial type-II cells facilitates pulmonary fibrosis through HSP90-AKT signaling restriction and AT-II apoptosis.
Comprehensive molecular analysis of genomic profiles and PD-L1 expression in lung adenocarcinoma with a high-grade fetal adenocarcinoma component.
Overexpression of the SARS-CoV-2 receptor ACE2 is induced by cigarette smoke in bronchial and alveolar epithelia.
Deficiency of CARMA3 attenuates the development of bleomycin induced pulmonary fibrosis.
Maimendong Decoction Improves Pulmonary Function in Rats With Idiopathic Pulmonary Fibrosis by Inhibiting Endoplasmic Reticulum Stress in AECIIs.
Amniotic fluid mesenchymal stromal cells from early stages of embryonic development have higher self-renewal potential.
Migrating Lung Monocytes Internalize and Inhibit Growth of Aspergillus fumigatus Conidia.
Vagal-α7nAChR signaling promotes lung stem cells regeneration via fibroblast growth factor 10 during lung injury repair.
Proteomic and ultrastructural analysis of Clara cell and type II alveolar epithelial cell-type lung cancer cells.
Human Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Alleviate Lung Injury in Rat Model of Bronchopulmonary Dysplasia by Affecting Cell Survival and Angiogenesis.
CPEB2-activated PDGFRα mRNA translation contributes to myofibroblast proliferation and pulmonary alveologenesis.
Novel insights into the role of LRRC8A in ameliorating alveolar fluid clearance in LPS induced acute lung injury.
Treatment with adipose tissue-derived mesenchymal stem cells exerts anti-diabetic effects, improves long-term complications, and attenuates inflammation in type 2 diabetic rats.
Overexpression of CXCR7 promotes mesenchymal stem cells to repair phosgene-induced acute lung injury in rats.
Deleterious Pulmonary Surfactant System Gene Mutations in Lung Adenocarcinomas Associated With Usual Interstitial Pneumonia.
A SCID mouse-human lung xenograft model of varicella-zoster virus infection.
Human amniotic fluid stem cells protect rat lungs exposed to moderate hyperoxia.
Zeng Q, Luo Y, Sang X, Liao M, Wen B, Hu Z, Sun M, Luo Z, Huang X, Liu W, Tang S
Antioxidants (Basel, Switzerland) 2024 May 31;13(6)
Antioxidants (Basel, Switzerland) 2024 May 31;13(6)
YAP/TAZ activation mediates PQ-induced lung fibrosis by sustaining senescent pulmonary epithelial cells.
Yu Y, Chu C, Wang K, Li Y, Mao Z, Hu L, Wang J, Yu Y, Sun H, Chen F
Respiratory research 2024 May 18;25(1):212
Respiratory research 2024 May 18;25(1):212
Tenascin-C modulates alveolarization in bronchopulmonary dysplasia.
Liu W, Mao Y, Lv Q, Lu K, Yin C, Cheng R, Zhang M
Inflammation and regeneration 2024 Mar 28;44(1):16
Inflammation and regeneration 2024 Mar 28;44(1):16
Protein lysine acetylation played an important role in NH(3)-induced AEC2 damage and pulmonary fibrosis in piglets.
Wang X, Zhang D, Zhu Y, Li D, Shen L, Wang Q, Gao Y, Li X, Yu M
The Science of the total environment 2024 Jan 15;908:168303
The Science of the total environment 2024 Jan 15;908:168303
Role of Sox9 in BPD and its effects on the Wnt/β-catenin pathway and AEC-II differentiation.
Wu D, Bai D, Yang M, Wu B, Xu W
Cell death discovery 2024 Jan 11;10(1):20
Cell death discovery 2024 Jan 11;10(1):20
Human milk exosome-derived circDNAJB6 improves bronchopulmonary dysplasia model by promoting DNAJB6 gene transcription.
Li Y, Yu B, Li H, Hou W, Yin J, Zhou Y, Yu Z
Journal of bioenergetics and biomembranes 2024 Apr;56(2):171-180
Journal of bioenergetics and biomembranes 2024 Apr;56(2):171-180
Pasteurella multocida activates apoptosis via the FAK-AKT-FOXO1 axis to cause pulmonary integrity loss, bacteremia, and eventually a cytokine storm.
Zhao G, Tang Y, Dan R, Xie M, Zhang T, Li P, He F, Li N, Peng Y
Veterinary research 2024 Apr 8;55(1):46
Veterinary research 2024 Apr 8;55(1):46
Evolutionary genetics of pulmonary anatomical adaptations in deep-diving cetaceans.
Guo B, Sun Y, Wang Y, Zhang Y, Zheng Y, Xu S, Yang G, Ren W
BMC genomics 2024 Apr 4;25(1):339
BMC genomics 2024 Apr 4;25(1):339
DEC1 is involved in circadian rhythm disruption-exacerbated pulmonary fibrosis.
Chen SJ, Yu F, Feng X, Li Q, Jiang YH, Zhao LQ, Cheng PP, Wang M, Song LJ, Liang LM, He XL, Xiong L, Xiang F, Wang X, Ye H, Ma WL
Cell communication and signaling : CCS 2024 Apr 26;22(1):245
Cell communication and signaling : CCS 2024 Apr 26;22(1):245
Downregulation of a potential therapeutic target NPAS2, regulated by p53, alleviates pulmonary fibrosis by inhibiting epithelial-mesenchymal transition via suppressing HES1.
Chen Y, He Z, Zhao B, Zheng R
Cellular signalling 2023 Sep;109:110795
Cellular signalling 2023 Sep;109:110795
Tat-P combined with GAPR1 releases Beclin1 to promote autophagy and improve Bronchopulmonary dysplasia model.
Zhou Y, Zhu Y, Jin W, Yan R, Fang Y, Zhang F, Tang T, Chen S, Chen J, Zhang F, Yu Z, Zang L, Yu Z
iScience 2023 Sep 15;26(9):107509
iScience 2023 Sep 15;26(9):107509
CircABPD1 alleviates oxidative lung injury of bronchopulmonary dysplasia through regulating miR-330-3p/HIF1α axis.
Li H, Ma K, Dou H, Liu L, Qian Y, Li S, Chen J, Han S, Gu X, Yin J
The international journal of biochemistry & cell biology 2023 Oct;163:106464
The international journal of biochemistry & cell biology 2023 Oct;163:106464
MICALL2 participates in the regulation of epithelial-mesenchymal transition in alveolar epithelial cells - Potential roles in pulmonary fibrosis.
Chen Y, Song W, Zhang H, Ji X
Archives of biochemistry and biophysics 2023 Oct 1;747:109730
Archives of biochemistry and biophysics 2023 Oct 1;747:109730
GBP2 upregulated in LPS-stimulated macrophages-derived exosomes accelerates septic lung injury by activating epithelial cell NLRP3 signaling.
Huang W, Zhang Y, Zheng B, Ling X, Wang G, Li L, Wang W, Pan M, Li X, Meng Y
International immunopharmacology 2023 Nov;124(Pt B):111017
International immunopharmacology 2023 Nov;124(Pt B):111017
Necroptosis signaling and NLRP3 inflammasome cross-talking in epithelium facilitate Pseudomonas aeruginosa mediated lung injury.
Li H, Guan J, Chen J, Sun W, Chen H, Wen Y, Chen Q, Xie S, Zhang X, Tao A, Yan J
Biochimica et biophysica acta. Molecular basis of disease 2023 Mar;1869(3):166613
Biochimica et biophysica acta. Molecular basis of disease 2023 Mar;1869(3):166613
Deletion of LCMR1 in alveolar type II cells induces lethal impairment of lung structure and function in adult mice.
Wang Y, Li C, Wu Z, Dai Y, Liu L, Chen L
Journal of thoracic disease 2023 Mar 31;15(3):1445-1459
Journal of thoracic disease 2023 Mar 31;15(3):1445-1459
Attenuation of PM(2.5)-induced alveolar epithelial cells and lung injury through regulation of mitochondrial fission and fusion.
Liu Q, Weng J, Li C, Feng Y, Xie M, Wang X, Chang Q, Li M, Chung KF, Adcock IM, Huang Y, Zhang H, Li F
Particle and fibre toxicology 2023 Jul 18;20(1):28
Particle and fibre toxicology 2023 Jul 18;20(1):28
Inhaled pulmonary surfactant biomimetic liposomes for reversing idiopathic pulmonary fibrosis through synergistic therapeutic strategy.
Wang B, Gao Y, Sun L, Xue M, Wang M, Zhang Z, Zhang L, Zhang H
Biomaterials 2023 Dec;303:122404
Biomaterials 2023 Dec;303:122404
Impact of Salt Intake and Renin-Angiotensin-Aldosterone System Blockade on Lung Severe Acute Respiratory Syndrome Coronavirus 2 Host Factors.
Zhang X, Liu L, Gaballa MMS, Hasan AA, Xiong Y, Xie L, Klein T, Delic D, Kleuser B, Krämer BK, Li J, Hocher B
Kidney & blood pressure research 2022;47(9):565-575
Kidney & blood pressure research 2022;47(9):565-575
D-tagatose protects against oleic acid-induced acute respiratory distress syndrome in rats by activating PTEN/PI3K/AKT pathway.
Huang J, Wang B, Tao S, Hu Y, Wang N, Zhang Q, Wang C, Chen C, Gao B, Cheng X, Li Y
Frontiers in immunology 2022;13:928312
Frontiers in immunology 2022;13:928312
A New Homotetramer Hemoglobin in the Pulmonary Surfactant of Plateau Zokors (Myospalax Baileyi).
Li J, An Z, Wei L, Xu B, Wang Z, Gao C, Wei L, Qi D, Shi P, Zhang T, Wei D
Frontiers in genetics 2022;13:824049
Frontiers in genetics 2022;13:824049
Claudin-18 expression under hyperoxia in neonatal lungs of bronchopulmonary dysplasia model rats.
Zuo J, Tong Y, Yang Y, Wang Y, Yue D
Frontiers in pediatrics 2022;10:916716
Frontiers in pediatrics 2022;10:916716
A homotetrameric hemoglobin expressed in alveolar epithelial cells increases blood oxygenation in high-altitude plateau pika (Ochotona curzoniae).
An Z, Wei L, Xu B, Wang Z, Gao C, Li J, Wei L, Qi D, Shi P, Zhang T, Wei D
Cell reports 2022 Oct 4;41(1):111446
Cell reports 2022 Oct 4;41(1):111446
Kub3 Deficiency Causes Aberrant Late Embryonic Lung Development in Mice by the FGF Signaling Pathway.
Yang G, Lu S, Jiang J, Weng J, Zeng X
International journal of molecular sciences 2022 May 27;23(11)
International journal of molecular sciences 2022 May 27;23(11)
HAO1-mediated oxalate metabolism promotes lung pre-metastatic niche formation by inducing neutrophil extracellular traps.
Zeng Z, Xu S, Wang F, Peng X, Zhang W, Zhan Y, Ding Y, Liu Z, Liang L
Oncogene 2022 Jul;41(29):3719-3731
Oncogene 2022 Jul;41(29):3719-3731
Human breast milk-derived exosomes through inhibiting AT II cell apoptosis to prevent bronchopulmonary dysplasia in rat lung.
Zhou Y, Liu Y, Xu G, Liu L, Li H, Li Y, Yin J, Wang X, Yu Z
Journal of cellular and molecular medicine 2022 Aug;26(15):4169-4182
Journal of cellular and molecular medicine 2022 Aug;26(15):4169-4182
A SCID mouse-human lung xenograft model of SARS-CoV-2 infection.
Fu W, Wang W, Yuan L, Lin Y, Huang X, Chen R, Cai M, Liu C, Chen L, Zhou M, Wu K, Zhao H, Pan D, Ma J, Hong J, Zhai B, Zhang Y, Kong Z, Wang Y, Chen Y, Yuan Q, Zhu H, Cheng T, Guan Y, Xia N
Theranostics 2021;11(13):6607-6615
Theranostics 2021;11(13):6607-6615
TSSK4 upregulation in alveolar epithelial type-II cells facilitates pulmonary fibrosis through HSP90-AKT signaling restriction and AT-II apoptosis.
Chen H, He A, Li H, Chen H, Xie H, Luo L, Huang Y, Chen J, Guan J, He Q, Ma J, Ou C, Tao A, Yan J
Cell death & disease 2021 Oct 13;12(10):938
Cell death & disease 2021 Oct 13;12(10):938
Comprehensive molecular analysis of genomic profiles and PD-L1 expression in lung adenocarcinoma with a high-grade fetal adenocarcinoma component.
Suzuki M, Kasajima R, Yokose T, Ito H, Shimizu E, Hatakeyama S, Yokoyama K, Yamaguchi R, Furukawa Y, Miyano S, Imoto S, Yoshioka E, Washimi K, Okubo Y, Kawachi K, Sato S, Miyagi Y
Translational lung cancer research 2021 Mar;10(3):1292-1304
Translational lung cancer research 2021 Mar;10(3):1292-1304
Overexpression of the SARS-CoV-2 receptor ACE2 is induced by cigarette smoke in bronchial and alveolar epithelia.
Liu A, Zhang X, Li R, Zheng M, Yang S, Dai L, Wu A, Hu C, Huang Y, Xie M, Chen Q
The Journal of pathology 2021 Jan;253(1):17-30
The Journal of pathology 2021 Jan;253(1):17-30
Deficiency of CARMA3 attenuates the development of bleomycin induced pulmonary fibrosis.
Wu Y, Qi Y, Qiu Z, Chen W
Biochemical and biophysical research communications 2021 Dec 3;581:81-88
Biochemical and biophysical research communications 2021 Dec 3;581:81-88
Maimendong Decoction Improves Pulmonary Function in Rats With Idiopathic Pulmonary Fibrosis by Inhibiting Endoplasmic Reticulum Stress in AECIIs.
Shen M, Nan Y, Zhang L, Di L, He S, Li Y, Li Y
Frontiers in pharmacology 2020;11:1262
Frontiers in pharmacology 2020;11:1262
Amniotic fluid mesenchymal stromal cells from early stages of embryonic development have higher self-renewal potential.
Huang J, Ma W, Wei X, Yuan Z
In vitro cellular & developmental biology. Animal 2020 Oct;56(9):701-714
In vitro cellular & developmental biology. Animal 2020 Oct;56(9):701-714
Migrating Lung Monocytes Internalize and Inhibit Growth of Aspergillus fumigatus Conidia.
Schiefermeier-Mach N, Haller T, Geley S, Perkhofer S
Pathogens (Basel, Switzerland) 2020 Nov 24;9(12)
Pathogens (Basel, Switzerland) 2020 Nov 24;9(12)
Vagal-α7nAChR signaling promotes lung stem cells regeneration via fibroblast growth factor 10 during lung injury repair.
Chen X, Zhao C, Zhang C, Li Q, Chen J, Cheng L, Zhou J, Su X, Song Y
Stem cell research & therapy 2020 Jun 10;11(1):230
Stem cell research & therapy 2020 Jun 10;11(1):230
Proteomic and ultrastructural analysis of Clara cell and type II alveolar epithelial cell-type lung cancer cells.
Hou WL, Chang M, Liu XF, Hu LS, Hua SC
Translational cancer research 2020 Feb;9(2):565-576
Translational cancer research 2020 Feb;9(2):565-576
Human Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Alleviate Lung Injury in Rat Model of Bronchopulmonary Dysplasia by Affecting Cell Survival and Angiogenesis.
You J, Zhou O, Liu J, Zou W, Zhang L, Tian D, Dai J, Luo Z, Liu E, Fu Z, Zou L
Stem cells and development 2020 Dec 1;29(23):1520-1532
Stem cells and development 2020 Dec 1;29(23):1520-1532
CPEB2-activated PDGFRα mRNA translation contributes to myofibroblast proliferation and pulmonary alveologenesis.
Lai YT, Chao HW, Lai AC, Lin SH, Chang YJ, Huang YS
Journal of biomedical science 2020 Apr 15;27(1):52
Journal of biomedical science 2020 Apr 15;27(1):52
Novel insights into the role of LRRC8A in ameliorating alveolar fluid clearance in LPS induced acute lung injury.
Zhang H, Liu Y, Li H, Li J, Luo Y, Yan X
European journal of pharmacology 2019 Oct 15;861:172613
European journal of pharmacology 2019 Oct 15;861:172613
Treatment with adipose tissue-derived mesenchymal stem cells exerts anti-diabetic effects, improves long-term complications, and attenuates inflammation in type 2 diabetic rats.
Yu S, Cheng Y, Zhang L, Yin Y, Xue J, Li B, Gong Z, Gao J, Mu Y
Stem cell research & therapy 2019 Nov 20;10(1):333
Stem cell research & therapy 2019 Nov 20;10(1):333
Overexpression of CXCR7 promotes mesenchymal stem cells to repair phosgene-induced acute lung injury in rats.
Shao Y, Zhou F, He D, Zhang L, Shen J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1233-1239
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jan;109:1233-1239
Deleterious Pulmonary Surfactant System Gene Mutations in Lung Adenocarcinomas Associated With Usual Interstitial Pneumonia.
Honda T, Sakashita H, Masai K, Totsuka H, Motoi N, Kobayashi M, Akashi T, Mimaki S, Tsuchihara K, Chiku S, Shiraishi K, Shimada Y, Otsuka A, Kanai Y, Okubo K, Watanabe SI, Tsuta K, Inase N, Kohno T
JCO precision oncology 2018 Nov;2:1-24
JCO precision oncology 2018 Nov;2:1-24
A SCID mouse-human lung xenograft model of varicella-zoster virus infection.
Wang W, Pan D, Fu W, Cai L, Ye J, Liu J, Liu C, Huang X, Lin Y, Xia N, Cheng T, Zhu H
Antiviral research 2017 Oct;146:45-53
Antiviral research 2017 Oct;146:45-53
Human amniotic fluid stem cells protect rat lungs exposed to moderate hyperoxia.
Grisafi D, Pozzobon M, Dedja A, Vanzo V, Tomanin R, Porzionato A, Macchi V, Salmaso R, Scarpa M, Cozzi E, Fassina A, Navaglia F, Maran C, Onisto M, Caenazzo L, De Coppi P, De Caro R, Chiandetti L, Zaramella P
Pediatric pulmonology 2013 Nov;48(11):1070-80
Pediatric pulmonology 2013 Nov;48(11):1070-80
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A549 cells were subjected to SDS PAGE followed by western blot with 10774-1-AP(SFTPC antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SFTPC antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SFTPC. This antibody recognizes human antigen. The SFTPC antibody has been validated for the following applications: ELISA, WB, IHC analysis.