Antibody data
- Antibody Data
- Antigen structure
- References [255]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 13584-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13584-1-AP, RRID:AB_2218915
- Product name
- YAP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated YAP1 antibody (Cat. #13584-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references RASSF4 Attenuates Metabolic Dysfunction-Associated Steatotic Liver Disease Progression via Hippo Signaling and Suppresses Hepatocarcinogenesis.
POU2F3-positive small cell carcinoma of the bladder: A clinicopathologic analysis of 4 cases and literature review.
m(6)A-induced TRIB3 regulates Hippo pathway through interacting with LATS1 to promote the progression of lung adenocarcinoma.
YAP/TAZ activation mediates PQ-induced lung fibrosis by sustaining senescent pulmonary epithelial cells.
Ischemia-inhibited ferric chelate reductase 1 improves ferroptosis-mediated intestinal ischemia injury via Hippo signaling.
Natural compound library screening to identify berberine as a treatment for rheumatoid arthritis.
YAP induces FAK phosphorylation to inhibit gastric cancer cell proliferation via upregulation of HMGB1.
LncRNA-SNHG5 mediates activation of hepatic stellate cells by regulating NF2 and Hippo pathway.
Increased extracellular matrix stiffness regulates myofibroblast transformation through induction of autophagy-mediated Kindlin-2 cytoplasmic translocation.
FTO attenuates the cytotoxicity of cisplatin in KGN granulosa cell-like tumour cells by regulating the Hippo/YAP1 signalling pathway.
Effects of gas signaling molecule SO(2) in cardiac functions of hyperthyroid rats.
Mechanisms of YAP1-mediated trophoblast ferroptosis in recurrent pregnancy loss.
Preventive effects of Ramelteon on bleomycin-induced pulmonary fibrosis in mice.
EphA2 promotes the transcription of KLF4 to facilitate stemness in oral squamous cell carcinoma.
Loss of FAM172A gene prompts cell proliferation in liver regeneration.
RNF144A-AS1 stabilizes TAF15 and promotes malignant biological behaviors of skin cutaneous melanoma.
Baicalein promotes KDM4E to induce BICD1 and inhibit triple-negative breast cancer progression by blocking PAR1 signaling.
ENO1 contributes to the gemcitabine resistance of pancreatic cancer through the YAP1 signaling pathway.
Overexpression of transcription factor TBX5 inhibits the activation of YAP1-TEAD1 pathway to promote ferroptosis in lung cancer cells.
Oridonin suppresses the growth of glioblastoma cells via inhibiting Hippo/YAP axis.
YAP1 expression in colorectal cancer confers the aggressive phenotypes via its target genes.
TGFβ and Hippo Signaling Pathways Coordinate to Promote Acinar to Ductal Metaplasia in Human Pancreas.
Involvement of Yes-Associated Protein 1 Activation in the Matrix Degradation of Human-Induced-Pluripotent-Stem-Cell-Derived Chondrocytes Induced by T-2 Toxin and Deoxynivalenol Alone and in Combination.
Decreased PDLIM1 expression in endothelial cells contributes to the development of intracranial aneurysm.
Upregulation of TRIM16 mitigates doxorubicin-induced cardiotoxicity by modulating TAK1 and YAP/Nrf2 pathways in mice.
Dinaciclib exerts a tumor-suppressing effect via β-catenin/YAP axis in pancreatic ductal adenocarcinoma.
High Hydrostatic Pressure Exacerbates Bladder Fibrosis through Activating Piezo1.
The Prognostic Biomarker RAB7A Promotes Growth and Metastasis of Liver Cancer Cells by Regulating Glycolysis and YAP1 Activation.
Endothelial H(2)S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis.
Stiffness assisted cell-matrix remodeling trigger 3D mechanotransduction regulatory programs.
Competence for neural crest induction is controlled by hydrostatic pressure through Yap.
Targeting mechanics-induced trabecular meshwork dysfunction through YAP-TGFβ Ameliorates high myopia-induced ocular hypertension.
The yes-associated protein-1 (YAP1) inhibitor celastrol suppresses the ability of transforming growth factor β to activate human gingival fibroblasts.
New daphnane diterpenoidal 1,3,4-oxdiazole derivatives as potential anti-hepatoma agents: Synthesis, biological evaluation and molecular modeling studies.
DNMT3A Cooperates with YAP/TAZ to Drive Gallbladder Cancer Metastasis.
The histone lysine acetyltransferase KAT2B inhibits cholangiocarcinoma growth: evidence for interaction with SP1 to regulate NF2-YAP signaling.
Tumor-associated macrophage-derived exosomal miR21-5p promotes tumor angiogenesis by regulating YAP1/HIF-1α axis in head and neck squamous cell carcinoma.
YAP1 synergize with YY1 transcriptional co-repress DUSP1 to induce osimertinib resistant by activating the EGFR/MAPK pathway and abrogating autophagy in non-small cell lung cancer.
Extracellular vesicles carrying miR-6836 derived from resistant tumor cells transfer cisplatin resistance of epithelial ovarian cancer via DLG2-YAP1 signaling pathway.
Recombinant humanized collagen remodels endometrial immune microenvironment of chronic endometritis through macrophage immunomodulation.
Ruscogenin ameliorates dasatinib-induced intestinal barrier dysfunction via ErbB4/YAP and ROCK/MLC pathways.
Stiff Substrate Induces Nucleus Pulposus Cell Ferroptosis via YAP and N-Cadherin Mediated Mechanotransduction.
Nucleosome assembly protein 1 like 1 (NAP1L1) promotes cardiac fibrosis by inhibiting YAP1 ubiquitination and degradation.
FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer.
Role of mechanotransduction mediated by YAP/TAZ in the treatment of neurogenic erectile dysfunction with low-intensity pulsed ultrasound.
Endothelial discoidin domain receptor 1 senses flow to modulate YAP activation.
Elastic modulus of hydrogel regulates osteogenic differentiation via liquid-liquid phase separation of YAP.
Role of DCLK1/Hippo pathway in type II alveolar epithelial cells differentiation in acute respiratory distress syndrome.
Circ_16601 facilitates Hippo pathway signaling via the miR-5580-5p/FGB axis to promote my-CAF recruitment in the TME and LUAD progression.
Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.
The deubiquitinating enzyme UCHL3 promotes anaplastic thyroid cancer progression and metastasis through Hippo signaling pathway.
N6-Methyladenosine-Mediated Up-Regulation of FZD10 Regulates Liver Cancer Stem Cells' Properties and Lenvatinib Resistance Through WNT/β-Catenin and Hippo Signaling Pathways.
EFHD1, a novel mitochondrial regulator of tumor metastasis in clear cell renal cell carcinoma.
Sema3G activates YAP and promotes VSMCs proliferation and migration via Nrp2/PlexinA1.
miR-183-5p overexpression orchestrates collective invasion in salivary adenoid cystic carcinoma through the FAT1/YAP1 signaling pathway.
The oncogenic role of NF1 in gallbladder cancer through regulation of YAP1 stability by direct interaction with YAP1.
KK-LC-1 as a therapeutic target to eliminate ALDH(+) stem cells in triple negative breast cancer.
Liver-specific overexpression of HKDC1 increases hepatocyte size and proliferative capacity.
YAP-regulated type II alveolar epithelial cell differentiation mediated by human umbilical cord-derived mesenchymal stem cells in acute respiratory distress syndrome.
Genipin Crosslinks the Extracellular Matrix to Rescue Developmental and Degenerative Defects, and Accelerates Regeneration of Peripheral Neurons.
LncRNA-MIAT activates hepatic stellate cells via regulating Hippo pathway and epithelial-to-mesenchymal transition.
Inflammation modulates intercellular adhesion and mechanotransduction in human epidermis via ROCK2.
USP1/UAF1-Stabilized METTL3 Promotes Reactive Astrogliosis and Improves Functional Recovery after Spinal Cord Injury through m(6)A Modification of YAP1 mRNA.
GPR97 deficiency ameliorates renal interstitial fibrosis in mouse hypertensive nephropathy.
YAP/TEAD1 and β-catenin/LEF1 synergistically induce estrogen receptor α to promote osteogenic differentiation of bone marrow stromal cells.
Mitoquinone ameliorated airway inflammation by stabilizing β-catenin destruction complex in a steroid-insensitive asthma model.
The role of mechano-regulated YAP/TAZ in erectile dysfunction.
Scarless wound healing programmed by core-shell microneedles.
FTO promotes cervical cancer cell proliferation, colony formation, migration and invasion via the regulation of the BMP4/Hippo/YAP1/TAZ pathway.
LATS-regulated nuclear-cytoplasmic translocation of SREBP2 inhibits hepatocellular carcinoma cell migration and invasion via epithelial-mesenchymal transition.
The circular RNA circHelz enhances cardiac fibrosis by facilitating the nuclear translocation of YAP1.
Targeting endothelial coagulation signaling ameliorates liver obstructive cholestasis and dysfunctional angiogenesis.
ZNF143 facilitates the growth and migration of glioma cells by regulating KPNA2-mediated Hippo signalling.
YAP1 controls the N-cadherin-mediated tumor-stroma interaction in melanoma progression.
Bifidobacterium adolescentis induces Decorin(+) macrophages via TLR2 to suppress colorectal carcinogenesis.
Jianpi Yangzheng decoction suppresses gastric cancer progression via modulating the miR-448/CLDN18.2 mediated YAP/TAZ signaling.
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
USP15 promotes pulmonary vascular remodeling in pulmonary hypertension in a YAP1/TAZ-dependent manner.
TEAD4 is a master regulator of high-risk nasopharyngeal carcinoma.
Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.
TPM2 attenuates progression of prostate cancer by blocking PDLIM7-mediated nuclear translocation of YAP1.
A modified apical resection model with high accuracy and reproducibility in neonatal mouse and rat hearts.
Silica nanoparticles suppressed the spermatogenesis via downregulation of miR-450b-3p by targeting Layilin in spermatocyte of mouse.
Effects of YAP1 on proliferation and differentiation of Hu sheep skeletal muscle satellite cells in vitro.
BMP4 participates in the pathogenesis of PCOS by regulating glucose metabolism and autophagy in granulosa cells under hyperandrogenic environment.
ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism.
Knockdown of Yap attenuates TAA-induced hepatic fibrosis by interaction with hedgehog signals.
Exosomes derived from mesenchymal stromal cells exert a therapeutic effect on hypoxia-induced pulmonary hypertension by modulating the YAP1/SPP1 signaling pathway.
IGF2BP1 enhances the stability of SIK2 mRNA through m(6)A modification to promote non-small cell lung cancer progression.
Hepatic Stellate Cell- and Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis.
MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression.
O‑GlcNAcylation mediates endometrial cancer progression by regulating the Hippo‑YAP pathway.
IGF2BP3/HIF1A/YAP signaling plays a role in driving acute-on-chronic liver failure through activating hepatocyte reprogramming.
SRSF3/AMOTL1 splicing axis promotes the tumorigenesis of nasopharyngeal carcinoma through regulating the nucleus translocation of YAP1.
Coexisting cancer stem cells with heterogeneous gene amplifications, transcriptional profiles, and malignancy are isolated from single glioblastomas.
Yes-associated protein inhibition ameliorates liver fibrosis and acute and chronic liver failure by decreasing ferroptosis and necroptosis.
Synergistic Effect of Magneto-Mechanical Bioengineered Stem Cells and Magnetic Field to Alleviate Osteoporosis.
Two-Pore-Domain Potassium Channel TREK-1 Mediates Pulmonary Fibrosis through Macrophage M2 Polarization and by Direct Promotion of Fibroblast Differentiation.
Chromatin Remodelling Molecule ARID1A Determines Metastatic Heterogeneity in Triple-Negative Breast Cancer by Competitively Binding to YAP.
LncRNA modulates Hippo-YAP signaling to reprogram iron metabolism.
KIAA1429-mediated m6A modification of CHST11 promotes progression of diffuse large B-cell lymphoma by regulating Hippo-YAP pathway.
Lipid-Sensing Receptor FFAR4 Modulates Pulmonary Epithelial Homeostasis following Immunogenic Exposures Independently of the FFAR4 Ligand Docosahexaenoic Acid (DHA).
The role of YAP1 in survival prediction, immune modulation, and drug response: A pan-cancer perspective.
TiO(2) Nanotubes Promote Osteogenic Differentiation Through Regulation of Yap and Piezo1.
Deacetylation of YAP1 Promotes the Resistance to Chemo- and Targeted Therapy in FLT3-ITD(+) AML Cells.
CircPAK1 promotes the progression of hepatocellular carcinoma via modulation of YAP nucleus localization by interacting with 14-3-3ζ.
Targeting of MCL-1 in breast cancer-associated fibroblasts reverses their myofibroblastic phenotype and pro-invasive properties.
A derivant of ginsenoside CK and its inhibitory effect on hepatocellular carcinoma.
Exploration of fetal growth restriction induced by vitamin D deficiency in rats via Hippo-YAP signaling pathway.
CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation.
Promotion of Melanoma Cell Proliferation by Cyclic Straining through Regulatory Morphogenesis.
Caveolin-1 and Its Functional Peptide CSP7 Affect Silica-Induced Pulmonary Fibrosis by Regulating Fibroblast Glutaminolysis.
RBCK1 is an endogenous inhibitor for triple negative breast cancer via hippo/YAP axis.
Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and ameliorates organ fibrosis.
mTORC1 signaling pathway integrates estrogen and growth factor to coordinate vaginal epithelial cells proliferation and differentiation.
PSMA1 mediates tumor progression and poor prognosis of gastric carcinoma by deubiquitinating and stabilizing TAZ.
Liposomal UHRF1 siRNA shows lung fibrosis treatment potential through regulation of fibroblast activation.
Glucocorticoids rapidly promote YAP phosphorylation via the cAMP-PKA pathway to repress mouse cardiomyocyte proliferative potential.
Electrochemically derived nanographene oxide activates endothelial tip cells and promotes angiogenesis by binding endogenous lysophosphatidic acid.
FERM domain-containing protein 6 exerts a tumor-inhibiting role in thyroid cancer by antagonizing oncogenic YAP1.
Polysaccharides from Platycodonis Radix ameliorated respiratory syncytial virus-induced epithelial cell apoptosis and inflammation through activation of miR-181a-mediated Hippo and SIRT1 pathways.
Novel insights into the mechanisms by which lncRNA HOTAIR regulates migration and invasion in HeLa cells.
Mechanical control of nuclear import by Importin-7 is regulated by its dominant cargo YAP.
Restraint of chaperonin containing T-complex protein-1 subunit 3 has antitumor roles in non-small cell lung cancer via affection of YAP1.
WISP2/CCN5 Suppresses Vasculogenic Mimicry through Inhibition of YAP/TAZ Signaling in Breast Cancer Cells.
Fusobacterium nucleatum reduces METTL3-mediated m(6)A modification and contributes to colorectal cancer metastasis.
SIRPγ-expressing cancer stem-like cells promote immune escape of lung cancer via Hippo signaling.
Divergent transcriptional regulation of astrocyte reactivity across disorders.
A myogenic niche with a proper mechanical stress environment improves abdominal wall muscle repair by modulating immunity and preventing fibrosis.
MicroRNA-122-5p Aggravates Angiotensin II-Mediated Myocardial Fibrosis and Dysfunction in Hypertensive Rats by Regulating the Elabela/Apelin-APJ and ACE2-GDF15-Porimin Signaling.
The proteasome-dependent degradation of ALKBH5 regulates ECM deposition in PM(2.5) exposure-induced pulmonary fibrosis of mice.
Centella asiatica (L.) Urb. attenuates cardiac hypertrophy and improves heart function through multi-level mechanisms revealed by systems pharmacology.
YAP/TAZ activity in stromal cells prevents ageing by controlling cGAS-STING.
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner.
Single-cell atlas of keratoconus corneas revealed aberrant transcriptional signatures and implicated mechanical stretch as a trigger for keratoconus pathogenesis.
miR-1307-5p suppresses proliferation and tumorigenesis of bladder cancer via targeting MDM4 and the Hippo signaling pathway.
The function of Nucleoporin 37 on mouse oocyte maturation and preimplantation embryo development.
Linc01133 contributes to gastric cancer growth by enhancing YES1-dependent YAP1 nuclear translocation via sponging miR-145-5p.
RNF6 promotes the migration and invasion of breast cancer by promoting the ubiquitination and degradation of MST1.
Profiling and functional characterization of maternal mRNA translation during mouse maternal-to-zygotic transition.
Acquired temozolomide resistance in MGMT(low) gliomas is associated with regulation of homologous recombination repair by ROCK2.
USP36 facilitates esophageal squamous carcinoma progression via stabilizing YAP.
Heterogeneous matrix stiffness regulates the cancer stem-like cell phenotype in hepatocellular carcinoma.
Effect of hypoxia on HIF-1α/MDR1/VEGF expression in gastric cancer cells treated with 5-fluorouracil.
Resveratrol inhibits proliferation and induces apoptosis via the Hippo/YAP pathway in human colon cancer cells.
Analysis of disordered abrasive scratches on titanium surfaces and their impact on nuclear translocation of yes-associated protein.
Knockdown of HSP110 attenuates hypoxia-induced pulmonary hypertension in mice through suppression of YAP/TAZ-TEAD4 pathway.
miR-596-3p suppresses brain metastasis of non-small cell lung cancer by modulating YAP1 and IL-8.
MiR-125b enhances doxorubicin-induced cardiotoxicity by suppressing the nucleus-cytoplasmic translocation of YAP via targeting STARD13.
SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer.
PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles.
Expression and Functional Relevance of ANXA1 in Hypopharyngeal Carcinoma with Lymph Node Metastasis.
Involvement of the TGF-β Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis.
Traditional Chinese medicine Yiqi Huoxue recipe attenuates hepatic fibrosis via YAP/TAZ signaling.
PPP1CA/YAP/GS/Gln/mTORC1 pathway activates retinal Müller cells during diabetic retinopathy.
MiR-200c-3p promotes ox-LDL-induced endothelial to mesenchymal transition in human umbilical vein endothelial cells through SMAD7/YAP pathway.
Reduced DAPK1 Expression Promotes Stem Cell-Like Characteristics of Prostate Cancer Cells by Activating ZEB1 via Hippo/YAP Signaling Pathway.
SGLT2 promotes pancreatic cancer progression by activating the Hippo signaling pathway via the hnRNPK-YAP1 axis.
Identification of YAP1 as a novel downstream effector of the FGF2/STAT3 pathway in the pathogenesis of renal tubulointerstitial fibrosis.
Delineating the heterogeneity of matrix-directed differentiation toward soft and stiff tissue lineages via single-cell profiling.
Overexpressed WDR3 induces the activation of Hippo pathway by interacting with GATA4 in pancreatic cancer.
Melatonin promotes cardiomyocyte proliferation and heart repair in mice with myocardial infarction via miR-143-3p/Yap/Ctnnd1 signaling pathway.
Long non-coding RNA muskelin 1 antisense RNA (MKLN1-AS) is a potential diagnostic and prognostic biomarker and therapeutic target for hepatocellular carcinoma.
Importance of Potential New Biomarkers in Patient with Serouse Ovarian Cancer.
Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development.
MINDY1 promotes bladder cancer progression by stabilizing YAP.
Prototypical oncogene family Myc defines unappreciated distinct lineage states of small cell lung cancer.
Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis.
AMOTL2 inhibits JUN Thr239 dephosphorylation by binding PPP2R2A to suppress the proliferation in non-small cell lung cancer cells.
S1P induces proliferation of pulmonary artery smooth muscle cells by promoting YAP-induced Notch3 expression and activation.
Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway.
Angiomotin-like 1 plays a tumor-promoting role in glioma by enhancing the activation of YAP1 signaling.
Loss of m(6)A methyltransferase METTL3 promotes heart regeneration and repair after myocardial injury.
Inhibiting roles of FOXA2 in liver cancer cell migration and invasion by transcriptionally suppressing microRNA-103a-3p and activating the GREM2/LATS2/YAP axis.
Uremic toxin indoxyl sulfate promotes proinflammatory macrophage activation by regulation of β-catenin and YAP pathways.
Circ-ITCH sponges miR-214 to promote the osteogenic differentiation in osteoporosis via upregulating YAP1.
Retinal dehydrogenase 5 (RHD5) attenuates metastasis via regulating HIPPO/YAP signaling pathway in Hepatocellular Carcinoma.
Calcipotriol Inhibits NLRP3 Signal Through YAP1 Activation to Alleviate Cholestatic Liver Injury and Fibrosis.
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.
CSRP2 suppresses colorectal cancer progression via p130Cas/Rac1 axis-meditated ERK, PAK, and HIPPO signaling pathways.
FAM83A Promotes Lung Cancer Progression by Regulating the Wnt and Hippo Signaling Pathways and Indicates Poor Prognosis.
YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways.
Genome-wide cooperation of EMT transcription factor ZEB1 with YAP and AP-1 in breast cancer.
MiR-375-3p alleviates the severity of inflammation through targeting YAP1/LEKTI pathway in HaCaT cells.
Eva-1 homolog A promotes papillary thyroid cancer progression and epithelial-mesenchymal transition via the Hippo signalling pathway.
Interaction of BACH2 with FUS promotes malignant progression of glioma cells via the TSLNC8-miR-10b-5p-WWC3 pathway.
Vitamin D3 analogue facilitates epithelial wound healing through promoting epithelial-mesenchymal transition via the Hippo pathway.
MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.
Gut microbiota transplantation from db/db mice induces diabetes-like phenotypes and alterations in Hippo signaling in pseudo germ-free mice.
Regulation of Hippo-YAP signaling by insulin-like growth factor-1 receptor in the tumorigenesis of diffuse large B-cell lymphoma.
Targeting LncDACH1 promotes cardiac repair and regeneration after myocardium infarction.
Effect of Maternal Age on Hippo Pathway Related Gene Expressions and Protein Localization Pattern in Human Embryos.
gga-microRNA-375 negatively regulates the cell cycle and proliferation by targeting Yes-associated protein 1 in DF-1 cells.
MALAT1 knockdown inhibits hypopharyngeal squamous cell carcinoma malignancy by targeting microRNA-194.
Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties.
PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.
Long noncoding RNA CASC21 exerts an oncogenic role in colorectal cancer through regulating miR-7-5p/YAP1 axis.
Retinal blood vessel-origin yes-associated protein (YAP) governs astrocytic maturation via leukaemia inhibitory factor (LIF).
RETRACTED: METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing.
Chondroitin synthase-3 regulates nucleus pulposus degeneration through actin-induced YAP signaling.
Role of RBM3 in the regulation of cell proliferation in hepatocellular carcinoma.
Arsenic nano complex induced degradation of YAP sensitized ESCC cancer cells to radiation and chemotherapy.
The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth.
Mechanisms of stretch-mediated skin expansion at single-cell resolution.
TRIB3 confers radiotherapy resistance in esophageal squamous cell carcinoma by stabilizing TAZ.
Estradiol-17β regulates proliferation and apoptosis of sheep endometrial epithelial cells by regulating the relative abundance of YAP1.
miR-25 Promotes Cell Proliferation, Migration, and Invasion of Non-Small-Cell Lung Cancer by Targeting the LATS2/YAP Signaling Pathway.
Jiedu Sangen Decoction Inhibits the Invasion and Metastasis of Colorectal Cancer Cells by Regulating EMT through the Hippo Signaling Pathway.
Downregulation of CENPK suppresses hepatocellular carcinoma malignant progression through regulating YAP1.
Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1.
Tumor Suppressor LKB1 inhibits both the mRNA Expression and the Amplification of hTERC by the Phosphorylation of YAP in Lung Cancer Cells.
miR-375-3p suppresses tumorigenesis and partially reverses chemoresistance by targeting YAP1 and SP1 in colorectal cancer cells.
Essential Oil from Pinus Koraiensis Pinecones Inhibits Gastric Cancer Cells via the HIPPO/YAP Signaling Pathway.
Differential Levels of Hippo Signaling in Selected Brain and Peripheral Tissues in Streptozotocin-Induced Cognitive Dysfunction in Mice.
F-actin dynamics regulates mammalian organ growth and cell fate maintenance.
LncRNA PFAR contributes to fibrogenesis in lung fibroblasts through competitively binding to miR-15a.
Circular RNA Vav3 sponges gga-miR-375 to promote epithelial-mesenchymal transition.
The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae.
Fufang Xueshuantong protects retinal vascular endothelial cells from high glucose by targeting YAP.
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
CLDN6 promotes tumor progression through the YAP1-snail1 axis in gastric cancer.
Myricetin Suppresses the Propagation of Hepatocellular Carcinoma via Down-Regulating Expression of YAP.
LncRNA PCGEM1 Induces Ovarian Carcinoma Tumorigenesis and Progression Through RhoA Pathway.
lncRNA PFAR Promotes Lung Fibroblast Activation and Fibrosis by Targeting miR-138 to Regulate the YAP1-Twist Axis.
Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress.
Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4.
Tumour YAP1 and PTEN expression correlates with tumour-associated myeloid suppressor cell expansion and reduced survival in colorectal cancer.
The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ.
Angiomotins stimulate LATS kinase autophosphorylation and act as scaffolds that promote Hippo signaling.
The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition.
REGγ deficiency suppresses tumor progression via stabilizing CK1ε in renal cell carcinoma.
YAP1 contributes to NSCLC invasion and migration by promoting Slug transcription via the transcription co-factor TEAD.
An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness.
ZEB1 stimulates breast cancer growth by up-regulating hTERT expression.
MicroRNA-200a confers chemoresistance by antagonizing TP53INP1 and YAP1 in human breast cancer.
Spatial patterning of liver progenitor cell differentiation mediated by cellular contractility and Notch signaling.
Melatonin Protects against Lung Fibrosis by Regulating the Hippo/YAP Pathway.
MiR-361 targets Yes-associated protein (YAP) mRNA to suppress cell proliferation in lung cancer.
Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling.
MiR-375 and Doxorubicin Co-delivered by Liposomes for Combination Therapy of Hepatocellular Carcinoma.
The oncoprotein HBXIP up-regulates YAP through activation of transcription factor c-Myb to promote growth of liver cancer.
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
E-Cadherin-Mediated Cell Contact Controls the Epidermal Damage Response in Radiation Dermatitis.
ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types.
Paper-based microreactor array for rapid screening of cell signaling cascades.
Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth.
Lats1 Deletion Causes Increased Germ Cell Apoptosis and Follicular Cysts in Mouse Ovaries.
A hairpin within YAP mRNA 3'UTR functions in regulation at post-transcription level.
Nicotine activates YAP1 through nAChRs mediated signaling in esophageal squamous cell cancer (ESCC).
MiR-506 suppresses proliferation of hepatoma cells through targeting YAP mRNA 3'UTR.
Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility.
Yes-associated protein (yap) is required for early embryonic development in zebrafish (danio rerio).
MicroRNA-200a promotes anoikis resistance and metastasis by targeting YAP1 in human breast cancer.
Hepatitis B virus X protein modulates oncogene Yes-associated protein by CREB to promote growth of hepatoma cells.
Hippo signaling regulates pancreas development through inactivation of Yap.
Xu C, Fang T, Qu J, Miao Y, Tian L, Zhang M, Zhuang H, Sun B, Chen L
Cellular and molecular gastroenterology and hepatology 2024;18(2):101348
Cellular and molecular gastroenterology and hepatology 2024;18(2):101348
POU2F3-positive small cell carcinoma of the bladder: A clinicopathologic analysis of 4 cases and literature review.
Cai Z, Cheng X, Liao S, Zou W, Li L, Liu F, Huang W
Pathology, research and practice 2024 May;257:155296
Pathology, research and practice 2024 May;257:155296
m(6)A-induced TRIB3 regulates Hippo pathway through interacting with LATS1 to promote the progression of lung adenocarcinoma.
Wu J, Yi T, Zhuo C, Wang D, Zhang M, Hu R, Wu D, Hou G, Xing Y
Journal of cellular physiology 2024 May;239(5):e31220
Journal of cellular physiology 2024 May;239(5):e31220
YAP/TAZ activation mediates PQ-induced lung fibrosis by sustaining senescent pulmonary epithelial cells.
Yu Y, Chu C, Wang K, Li Y, Mao Z, Hu L, Wang J, Yu Y, Sun H, Chen F
Respiratory research 2024 May 18;25(1):212
Respiratory research 2024 May 18;25(1):212
Ischemia-inhibited ferric chelate reductase 1 improves ferroptosis-mediated intestinal ischemia injury via Hippo signaling.
Liang P, Xie W, Wang X, Du Z, Zheng C, Zhao H, Wang Z, Ji Z
International immunopharmacology 2024 May 10;132:111900
International immunopharmacology 2024 May 10;132:111900
Natural compound library screening to identify berberine as a treatment for rheumatoid arthritis.
Zhang L, Tan M, Mao J, Zhang J, Wang XY, Zhang Y, Duo RX, Hao JY, Shen HL
Clinical rheumatology 2024 Mar;43(3):959-969
Clinical rheumatology 2024 Mar;43(3):959-969
YAP induces FAK phosphorylation to inhibit gastric cancer cell proliferation via upregulation of HMGB1.
Jiang Y, Fu L, Liu B, Li F
International journal of biological macromolecules 2024 Mar;262(Pt 1):130037
International journal of biological macromolecules 2024 Mar;262(Pt 1):130037
LncRNA-SNHG5 mediates activation of hepatic stellate cells by regulating NF2 and Hippo pathway.
Zhang R, Zhan Y, Lang Z, Li Y, Zhang W, Zheng J
Communications biology 2024 Mar 4;7(1):266
Communications biology 2024 Mar 4;7(1):266
Increased extracellular matrix stiffness regulates myofibroblast transformation through induction of autophagy-mediated Kindlin-2 cytoplasmic translocation.
Zhao Z, Han W, Huang G, He Y, Zuo X, Hong L
Experimental cell research 2024 Mar 15;436(2):113974
Experimental cell research 2024 Mar 15;436(2):113974
FTO attenuates the cytotoxicity of cisplatin in KGN granulosa cell-like tumour cells by regulating the Hippo/YAP1 signalling pathway.
Wang R, Cheng F, Yang X
Journal of ovarian research 2024 Mar 15;17(1):62
Journal of ovarian research 2024 Mar 15;17(1):62
Effects of gas signaling molecule SO(2) in cardiac functions of hyperthyroid rats.
Yang Q, Yang T, Liu X, Liu S, Liu W, Nie L, Chu C, Yang J
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Mar 1;28(2):129-143
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Mar 1;28(2):129-143
Mechanisms of YAP1-mediated trophoblast ferroptosis in recurrent pregnancy loss.
Chen L, Dai F, Huang Y, Chen J, Li Z, Liu H, Cheng Y
Journal of assisted reproduction and genetics 2024 Jun;41(6):1669-1685
Journal of assisted reproduction and genetics 2024 Jun;41(6):1669-1685
Preventive effects of Ramelteon on bleomycin-induced pulmonary fibrosis in mice.
Zhang L, Cheng T, Chen W, Zhong C, Li M, Xie Y, Deng Q, Wang H, Yang Z, Ju J, Liang H
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4153-4163
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4153-4163
EphA2 promotes the transcription of KLF4 to facilitate stemness in oral squamous cell carcinoma.
Bai J, Chen Y, Sun Y, Wang X, Wang Y, Guo S, Shang Z, Shao Z
Cellular and molecular life sciences : CMLS 2024 Jun 25;81(1):278
Cellular and molecular life sciences : CMLS 2024 Jun 25;81(1):278
Loss of FAM172A gene prompts cell proliferation in liver regeneration.
Wei H, Zhang Y, Gao M, Yang J, Wang S, Zhou X, Wei H, Xiao F
Molecular and cellular biochemistry 2024 Jun 19;
Molecular and cellular biochemistry 2024 Jun 19;
RNF144A-AS1 stabilizes TAF15 and promotes malignant biological behaviors of skin cutaneous melanoma.
Yang S, Sun Y, Wang N, Yang Z, Xing H, Jia J
Molecular and cellular biochemistry 2024 Jun 15;
Molecular and cellular biochemistry 2024 Jun 15;
Baicalein promotes KDM4E to induce BICD1 and inhibit triple-negative breast cancer progression by blocking PAR1 signaling.
Dong Y, He G, Chen K, He X, Pan M, Huang X, Yu X, Xia J
Molecular carcinogenesis 2024 Jul;63(7):1288-1302
Molecular carcinogenesis 2024 Jul;63(7):1288-1302
ENO1 contributes to the gemcitabine resistance of pancreatic cancer through the YAP1 signaling pathway.
Ma H, Kong L, Liu L, Du Y, Zhu X, Wang J, Zhao W
Molecular carcinogenesis 2024 Jul;63(7):1221-1234
Molecular carcinogenesis 2024 Jul;63(7):1221-1234
Overexpression of transcription factor TBX5 inhibits the activation of YAP1-TEAD1 pathway to promote ferroptosis in lung cancer cells.
Ma R, Hu K, Dai S, Wang Y
Biochemical and biophysical research communications 2024 Jul 23;718:150037
Biochemical and biophysical research communications 2024 Jul 23;718:150037
Oridonin suppresses the growth of glioblastoma cells via inhibiting Hippo/YAP axis.
Wang C, Zhang Y, Jiang Q, Chen S, Zhang L, Qiu H
Archives of biochemistry and biophysics 2024 Jan;751:109845
Archives of biochemistry and biophysics 2024 Jan;751:109845
YAP1 expression in colorectal cancer confers the aggressive phenotypes via its target genes.
Chen H, Shang Y, Li X, Wang R
Cell cycle (Georgetown, Tex.) 2024 Jan;23(1):83-91
Cell cycle (Georgetown, Tex.) 2024 Jan;23(1):83-91
TGFβ and Hippo Signaling Pathways Coordinate to Promote Acinar to Ductal Metaplasia in Human Pancreas.
Nipper M, Xu Y, Liu J, Yin X, Liu Z, Ye Z, Zhang J, Chen Y, Wang P
Cells 2024 Jan 18;13(2)
Cells 2024 Jan 18;13(2)
Involvement of Yes-Associated Protein 1 Activation in the Matrix Degradation of Human-Induced-Pluripotent-Stem-Cell-Derived Chondrocytes Induced by T-2 Toxin and Deoxynivalenol Alone and in Combination.
Liu L, Liu H, Meng P, Zhang Y, Zhang F, Jia Y, Cheng B, Lammi MJ, Zhang F, Guo X
International journal of molecular sciences 2024 Jan 10;25(2)
International journal of molecular sciences 2024 Jan 10;25(2)
Decreased PDLIM1 expression in endothelial cells contributes to the development of intracranial aneurysm.
Yan Y, Qin X, Zheng Y, Jin T, Hu Y, An Q, Leng B
Vascular medicine (London, England) 2024 Feb;29(1):5-16
Vascular medicine (London, England) 2024 Feb;29(1):5-16
Upregulation of TRIM16 mitigates doxorubicin-induced cardiotoxicity by modulating TAK1 and YAP/Nrf2 pathways in mice.
Guo X, Liu M, Han B, Zheng Y, Zhang K, Bao G, Gao C, Shi H, Sun Q, Zhao Z
Biochemical pharmacology 2024 Feb;220:116009
Biochemical pharmacology 2024 Feb;220:116009
Dinaciclib exerts a tumor-suppressing effect via β-catenin/YAP axis in pancreatic ductal adenocarcinoma.
Li Y, Zheng Z, Xiao L, Chen Y, Liu X, Long D, Chai L, Li Y, Tan C
Anti-cancer drugs 2024 Feb 1;35(2):140-154
Anti-cancer drugs 2024 Feb 1;35(2):140-154
High Hydrostatic Pressure Exacerbates Bladder Fibrosis through Activating Piezo1.
Deng BL, Lin DX, Li ZP, Li K, Wei PY, Luo CC, Zhang MY, Zhou Q, Yang ZL, Chen Z
Current medical science 2024 Aug;44(4):718-725
Current medical science 2024 Aug;44(4):718-725
The Prognostic Biomarker RAB7A Promotes Growth and Metastasis of Liver Cancer Cells by Regulating Glycolysis and YAP1 Activation.
Zhang JY, Zhu X, Liu Y, Wu X
Journal of cellular biochemistry 2024 Aug;125(8):e30621
Journal of cellular biochemistry 2024 Aug;125(8):e30621
Endothelial H(2)S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis.
Chen X, Wang H, Wu C, Li X, Huang X, Ren Y, Pu Q, Cao Z, Tang X, Ding BS
Redox biology 2024 Apr;70:103038
Redox biology 2024 Apr;70:103038
Stiffness assisted cell-matrix remodeling trigger 3D mechanotransduction regulatory programs.
Kersey AL, Cheng DY, Deo KA, Dubell CR, Wang TC, Jaiswal MK, Kim MH, Murali A, Hargett SE, Mallick S, Lele TP, Singh I, Gaharwar AK
Biomaterials 2024 Apr;306:122473
Biomaterials 2024 Apr;306:122473
Competence for neural crest induction is controlled by hydrostatic pressure through Yap.
Alasaadi DN, Alvizi L, Hartmann J, Stillman N, Moghe P, Hiiragi T, Mayor R
Nature cell biology 2024 Apr;26(4):530-541
Nature cell biology 2024 Apr;26(4):530-541
Targeting mechanics-induced trabecular meshwork dysfunction through YAP-TGFβ Ameliorates high myopia-induced ocular hypertension.
Bu Q, Zhu H, Cao G, Gong G, Su Y, Ge Q, Zhu W, Li Z, Pan X
Experimental eye research 2024 Apr;241:109853
Experimental eye research 2024 Apr;241:109853
The yes-associated protein-1 (YAP1) inhibitor celastrol suppresses the ability of transforming growth factor β to activate human gingival fibroblasts.
Naik A, Chitturi P, Nguyen J, Leask A
Archives of oral biology 2024 Apr;160:105910
Archives of oral biology 2024 Apr;160:105910
New daphnane diterpenoidal 1,3,4-oxdiazole derivatives as potential anti-hepatoma agents: Synthesis, biological evaluation and molecular modeling studies.
Wang X, Wang Y, Liu Z, Zhao H, Yao GD, Liu Q, Song SJ
Bioorganic chemistry 2024 Apr;145:107208
Bioorganic chemistry 2024 Apr;145:107208
DNMT3A Cooperates with YAP/TAZ to Drive Gallbladder Cancer Metastasis.
Xu S, Yuan Z, Jiang C, Chen W, Li Q, Chen T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(16):e2308531
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(16):e2308531
The histone lysine acetyltransferase KAT2B inhibits cholangiocarcinoma growth: evidence for interaction with SP1 to regulate NF2-YAP signaling.
Ma W, Zhang J, Chen W, Liu N, Wu T
Journal of experimental & clinical cancer research : CR 2024 Apr 19;43(1):117
Journal of experimental & clinical cancer research : CR 2024 Apr 19;43(1):117
Tumor-associated macrophage-derived exosomal miR21-5p promotes tumor angiogenesis by regulating YAP1/HIF-1α axis in head and neck squamous cell carcinoma.
Yan Q, Liu J, Liu Y, Wen Z, Jin D, Wang F, Gao L
Cellular and molecular life sciences : CMLS 2024 Apr 11;81(1):179
Cellular and molecular life sciences : CMLS 2024 Apr 11;81(1):179
YAP1 synergize with YY1 transcriptional co-repress DUSP1 to induce osimertinib resistant by activating the EGFR/MAPK pathway and abrogating autophagy in non-small cell lung cancer.
Ning Y, Zheng H, Yang Y, Zang H, Wang W, Zhan Y, Wang H, Luo J, Wen Q, Peng J, Xiang J, Fan S
International journal of biological sciences 2023;19(8):2458-2474
International journal of biological sciences 2023;19(8):2458-2474
Extracellular vesicles carrying miR-6836 derived from resistant tumor cells transfer cisplatin resistance of epithelial ovarian cancer via DLG2-YAP1 signaling pathway.
Zou Y, Zhao Z, Wang J, Ma L, Liu Y, Sun L, Song Y
International journal of biological sciences 2023;19(10):3099-3114
International journal of biological sciences 2023;19(10):3099-3114
Recombinant humanized collagen remodels endometrial immune microenvironment of chronic endometritis through macrophage immunomodulation.
You S, Zhu Y, Li H, He F, Liu S, Yang X, Wang L, Zeng H, Dai J, Hu L
Regenerative biomaterials 2023;10:rbad033
Regenerative biomaterials 2023;10:rbad033
Ruscogenin ameliorates dasatinib-induced intestinal barrier dysfunction via ErbB4/YAP and ROCK/MLC pathways.
Huang J, Zhou J, Dai Y, Liu Y, Li F, Gong S, Zhang Y, Kou J
Journal of natural medicines 2023 Sep;77(4):735-747
Journal of natural medicines 2023 Sep;77(4):735-747
Stiff Substrate Induces Nucleus Pulposus Cell Ferroptosis via YAP and N-Cadherin Mediated Mechanotransduction.
Ke W, Liao Z, Liang H, Tong B, Song Y, Li G, Ma L, Wang K, Feng X, Li S, Hua W, Wang B, Yang C
Advanced healthcare materials 2023 Sep;12(23):e2300458
Advanced healthcare materials 2023 Sep;12(23):e2300458
Nucleosome assembly protein 1 like 1 (NAP1L1) promotes cardiac fibrosis by inhibiting YAP1 ubiquitination and degradation.
Li T, Niu Z, Yu T, Li J, Lu X, Huang M, Wang Q, Yu X, Feng J, Xu B, Bing D, Li X, Lu L, Liang H, Yang R, Wang B, Shan H
MedComm 2023 Oct;4(5):e348
MedComm 2023 Oct;4(5):e348
FN1 mediated activation of aspartate metabolism promotes the progression of triple-negative and luminal a breast cancer.
Chen C, Ye L, Yi J, Liu T, Li Z
Breast cancer research and treatment 2023 Oct;201(3):515-533
Breast cancer research and treatment 2023 Oct;201(3):515-533
Role of mechanotransduction mediated by YAP/TAZ in the treatment of neurogenic erectile dysfunction with low-intensity pulsed ultrasound.
Liu Y, Pan XY, Zhang XX, Sun JL, Mao YH, Yang Y, Wei ZT
Andrology 2023 Oct;11(7):1514-1527
Andrology 2023 Oct;11(7):1514-1527
Endothelial discoidin domain receptor 1 senses flow to modulate YAP activation.
Liu J, Zhao C, Xiao X, Li A, Liu Y, Zhao J, Fan L, Liang Z, Pang W, Yao W, Li W, Zhou J
Nature communications 2023 Oct 13;14(1):6457
Nature communications 2023 Oct 13;14(1):6457
Elastic modulus of hydrogel regulates osteogenic differentiation via liquid-liquid phase separation of YAP.
Tan K, Yang Q, Han Y, Zhuang Z, Zhao Y, Guo K, Tan A, Zheng Y, Li W
Journal of biomedical materials research. Part A 2023 Nov;111(11):1781-1797
Journal of biomedical materials research. Part A 2023 Nov;111(11):1781-1797
Role of DCLK1/Hippo pathway in type II alveolar epithelial cells differentiation in acute respiratory distress syndrome.
Chen XY, Kao C, Peng SW, Chang JH, Lee YL, Laiman V, Chung KF, Bhavsar PK, Heriyanto DS, Chuang KJ, Chuang HC
Molecular medicine (Cambridge, Mass.) 2023 Nov 23;29(1):159
Molecular medicine (Cambridge, Mass.) 2023 Nov 23;29(1):159
Circ_16601 facilitates Hippo pathway signaling via the miR-5580-5p/FGB axis to promote my-CAF recruitment in the TME and LUAD progression.
Zhou J, Li P, Zhao X, Zhao Y, Luo J, Deng Y, Jiang N, Xiao Z, Zhang W, Zhou Y, Zhao J, Li P, Li Y, Tian Z
Respiratory research 2023 Nov 12;24(1):276
Respiratory research 2023 Nov 12;24(1):276
Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.
Guo Y, Cui Y, Li Y, Jin X, Wang D, Lei M, Chen F, Liu Y, Xu J, Yao G, Zeng G, Chen X
Cancer communications (London, England) 2023 May;43(5):582-612
Cancer communications (London, England) 2023 May;43(5):582-612
The deubiquitinating enzyme UCHL3 promotes anaplastic thyroid cancer progression and metastasis through Hippo signaling pathway.
Tang J, Yang Q, Mao C, Xiao D, Liu S, Xiao L, Zhou L, Wu G, Tao Y
Cell death and differentiation 2023 May;30(5):1247-1259
Cell death and differentiation 2023 May;30(5):1247-1259
N6-Methyladenosine-Mediated Up-Regulation of FZD10 Regulates Liver Cancer Stem Cells' Properties and Lenvatinib Resistance Through WNT/β-Catenin and Hippo Signaling Pathways.
Wang J, Yu H, Dong W, Zhang C, Hu M, Ma W, Jiang X, Li H, Yang P, Xiang D
Gastroenterology 2023 May;164(6):990-1005
Gastroenterology 2023 May;164(6):990-1005
EFHD1, a novel mitochondrial regulator of tumor metastasis in clear cell renal cell carcinoma.
Meng K, Hu Y, Wang D, Li Y, Shi F, Lu J, Wang Y, Cao Y, Zhang CZ, He QY
Cancer science 2023 May;114(5):2029-2040
Cancer science 2023 May;114(5):2029-2040
Sema3G activates YAP and promotes VSMCs proliferation and migration via Nrp2/PlexinA1.
Luo XY, Fu X, Liu F, Luo JY, Chen AF
Cellular signalling 2023 May;105:110613
Cellular signalling 2023 May;105:110613
miR-183-5p overexpression orchestrates collective invasion in salivary adenoid cystic carcinoma through the FAT1/YAP1 signaling pathway.
Chen BJ, Jiang J, Li T, Jiang HJ, Liang XH, Tang YL
Biochemical and biophysical research communications 2023 May 7;655:127-137
Biochemical and biophysical research communications 2023 May 7;655:127-137
The oncogenic role of NF1 in gallbladder cancer through regulation of YAP1 stability by direct interaction with YAP1.
Zhang L, Jiang L, Zeng L, Jin Z, Dong X, Zhang Y, Chen L, Shu Y, Liu Y, Huang Y
Journal of translational medicine 2023 May 5;21(1):306
Journal of translational medicine 2023 May 5;21(1):306
KK-LC-1 as a therapeutic target to eliminate ALDH(+) stem cells in triple negative breast cancer.
Bu J, Zhang Y, Wu S, Li H, Sun L, Liu Y, Zhu X, Qiao X, Ma Q, Liu C, Niu N, Xue J, Chen G, Yang Y, Liu C
Nature communications 2023 May 5;14(1):2602
Nature communications 2023 May 5;14(1):2602
Liver-specific overexpression of HKDC1 increases hepatocyte size and proliferative capacity.
Pusec CM, Ilievski V, De Jesus A, Farooq Z, Zapater JL, Sweis N, Ismail H, Khan MW, Ardehali H, Cordoba-Chacon J, Layden BT
Scientific reports 2023 May 17;13(1):8034
Scientific reports 2023 May 17;13(1):8034
YAP-regulated type II alveolar epithelial cell differentiation mediated by human umbilical cord-derived mesenchymal stem cells in acute respiratory distress syndrome.
Chen XY, Chen KY, Feng PH, Lee KY, Fang YT, Chen YY, Lo YC, Bhavsar PK, Chung KF, Chuang HC
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Mar;159:114302
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Mar;159:114302
Genipin Crosslinks the Extracellular Matrix to Rescue Developmental and Degenerative Defects, and Accelerates Regeneration of Peripheral Neurons.
Saito-Diaz K, Dietrich P, Wu HF, Sun X, Patel AJ, Wzientek CG, Prudden AR, Boons GJ, Chen S, Studer L, Xu B, Dragatsis I, Zeltner N
bioRxiv : the preprint server for biology 2023 Mar 24;
bioRxiv : the preprint server for biology 2023 Mar 24;
LncRNA-MIAT activates hepatic stellate cells via regulating Hippo pathway and epithelial-to-mesenchymal transition.
Zhan Y, Tao Q, Meng Q, Zhang R, Lin L, Li X, Zheng L, Zheng J
Communications biology 2023 Mar 18;6(1):285
Communications biology 2023 Mar 18;6(1):285
Inflammation modulates intercellular adhesion and mechanotransduction in human epidermis via ROCK2.
Shutova MS, Borowczyk J, Russo B, Sellami S, Drukala J, Wolnicki M, Brembilla NC, Kaya G, Ivanov AI, Boehncke WH
iScience 2023 Mar 17;26(3):106195
iScience 2023 Mar 17;26(3):106195
USP1/UAF1-Stabilized METTL3 Promotes Reactive Astrogliosis and Improves Functional Recovery after Spinal Cord Injury through m(6)A Modification of YAP1 mRNA.
Ge X, Ye W, Zhu Y, Cui M, Zhou J, Xiao C, Jiang D, Tang P, Wang J, Wang Z, Ji C, Zhou X, Cao X, Liu W, Cai W
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Mar 1;43(9):1456-1474
The Journal of neuroscience : the official journal of the Society for Neuroscience 2023 Mar 1;43(9):1456-1474
GPR97 deficiency ameliorates renal interstitial fibrosis in mouse hypertensive nephropathy.
Wu JC, Wang XJ, Zhu JH, Huang XY, Liu M, Qiao Z, Zhang Y, Sun Y, Wang ZY, Zhan P, Zhang T, Hu HL, Liu H, Tang W, Yi F
Acta pharmacologica Sinica 2023 Jun;44(6):1206-1216
Acta pharmacologica Sinica 2023 Jun;44(6):1206-1216
YAP/TEAD1 and β-catenin/LEF1 synergistically induce estrogen receptor α to promote osteogenic differentiation of bone marrow stromal cells.
Wang P, Huang L, Yang F, Chen W, Bai D, Guo Y
MedComm 2023 Jun;4(3):e246
MedComm 2023 Jun;4(3):e246
Mitoquinone ameliorated airway inflammation by stabilizing β-catenin destruction complex in a steroid-insensitive asthma model.
Huang J, Chen Y, Peng X, Gong Z, Wang Y, Li Y, Xu M, Ma Y, Yu C, Cai S, Zhao W, Zhao H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114680
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114680
The role of mechano-regulated YAP/TAZ in erectile dysfunction.
Ji M, Chen D, Shu Y, Dong S, Zhang Z, Zheng H, Jin X, Zheng L, Liu Y, Zheng Y, Zhang W, Wang S, Zhou G, Li B, Ji B, Yang Y, Xu Y, Chang L
Nature communications 2023 Jun 23;14(1):3758
Nature communications 2023 Jun 23;14(1):3758
Scarless wound healing programmed by core-shell microneedles.
Zhang Y, Wang S, Yang Y, Zhao S, You J, Wang J, Cai J, Wang H, Wang J, Zhang W, Yu J, Han C, Zhang Y, Gu Z
Nature communications 2023 Jun 10;14(1):3431
Nature communications 2023 Jun 10;14(1):3431
FTO promotes cervical cancer cell proliferation, colony formation, migration and invasion via the regulation of the BMP4/Hippo/YAP1/TAZ pathway.
Huang J, Yang J, Zhang Y, Lu D, Dai Y
Experimental cell research 2023 Jun 1;427(1):113585
Experimental cell research 2023 Jun 1;427(1):113585
LATS-regulated nuclear-cytoplasmic translocation of SREBP2 inhibits hepatocellular carcinoma cell migration and invasion via epithelial-mesenchymal transition.
Zhang F, Gao J, Liu X, Sun Y, Liu L, Hu B, Wang Z, Shi J, Guo W, Zhang S
Molecular carcinogenesis 2023 Jul;62(7):963-974
Molecular carcinogenesis 2023 Jul;62(7):963-974
The circular RNA circHelz enhances cardiac fibrosis by facilitating the nuclear translocation of YAP1.
Pang P, Si W, Wu H, Wang C, Liu K, Jia Y, Zhang Z, Zhang F, Kong X, Yang Y, Jiang W, Song J, Zeng L, Xiong Y, Lian J, Wang N, Bian Y, Yang B
Translational research : the journal of laboratory and clinical medicine 2023 Jul;257:30-42
Translational research : the journal of laboratory and clinical medicine 2023 Jul;257:30-42
Targeting endothelial coagulation signaling ameliorates liver obstructive cholestasis and dysfunctional angiogenesis.
Yang X, Ou Y, Yang Y, Wang L, Zhang Y, Zhao F, Shui P, Qing J
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1242-1253
Experimental biology and medicine (Maywood, N.J.) 2023 Jul;248(14):1242-1253
ZNF143 facilitates the growth and migration of glioma cells by regulating KPNA2-mediated Hippo signalling.
Chen Y, Li J, Ma J, Bao Y
Scientific reports 2023 Jul 9;13(1):11097
Scientific reports 2023 Jul 9;13(1):11097
YAP1 controls the N-cadherin-mediated tumor-stroma interaction in melanoma progression.
Xio Y, Zhou L, Andl T, Zhang Y
Research square 2023 Jul 28;
Research square 2023 Jul 28;
Bifidobacterium adolescentis induces Decorin(+) macrophages via TLR2 to suppress colorectal carcinogenesis.
Lin Y, Fan L, Qi Y, Xu C, Jia D, Jiang Y, Chen S, Wang L
Journal of experimental & clinical cancer research : CR 2023 Jul 18;42(1):172
Journal of experimental & clinical cancer research : CR 2023 Jul 18;42(1):172
Jianpi Yangzheng decoction suppresses gastric cancer progression via modulating the miR-448/CLDN18.2 mediated YAP/TAZ signaling.
Xu X, Li Y, Zhang R, Chen X, Shen J, Yuan M, Chen Y, Chen M, Liu S, Wu J, Sun Q
Journal of ethnopharmacology 2023 Jul 15;311:116450
Journal of ethnopharmacology 2023 Jul 15;311:116450
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
Chen H, Yang W, Li Y, Ji Z
Cell death & disease 2023 Jul 15;14(7):433
Cell death & disease 2023 Jul 15;14(7):433
USP15 promotes pulmonary vascular remodeling in pulmonary hypertension in a YAP1/TAZ-dependent manner.
Wu Z, Zhu L, Nie X, Wei L, Qi Y
Experimental & molecular medicine 2023 Jan;55(1):183-195
Experimental & molecular medicine 2023 Jan;55(1):183-195
TEAD4 is a master regulator of high-risk nasopharyngeal carcinoma.
Wang YQ, Wu DH, Wei D, Shen JY, Huang ZW, Liang XY, Cho WCS, Ma J, Lv J, Chen YP
Science advances 2023 Jan 6;9(1):eadd0960
Science advances 2023 Jan 6;9(1):eadd0960
Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.
Cao YF, Xie L, Tong BB, Chu MY, Shi WQ, Li X, He JZ, Wang SH, Wu ZY, Deng DX, Zheng YQ, Li ZM, Xu XE, Liao LD, Cheng YW, Li LY, Xu LY, Li EM
Cell death and differentiation 2023 Feb;30(2):527-543
Cell death and differentiation 2023 Feb;30(2):527-543
TPM2 attenuates progression of prostate cancer by blocking PDLIM7-mediated nuclear translocation of YAP1.
Wu Z, Ge L, Ma L, Lu M, Song Y, Deng S, Duan P, Du T, Wu Y, Zhang Z, Zhang S
Cell & bioscience 2023 Feb 23;13(1):39
Cell & bioscience 2023 Feb 23;13(1):39
A modified apical resection model with high accuracy and reproducibility in neonatal mouse and rat hearts.
Bei Y, Chen C, Hua X, Yin M, Meng X, Huang Z, Qi W, Su Z, Liu C, Lehmann HI, Li G, Huang Y, Xiao J
NPJ Regenerative medicine 2023 Feb 18;8(1):9
NPJ Regenerative medicine 2023 Feb 18;8(1):9
Silica nanoparticles suppressed the spermatogenesis via downregulation of miR-450b-3p by targeting Layilin in spermatocyte of mouse.
Zhou G, Wang J, Ren L, Liu J, Li X, Zhang Y, Sang Y, Gao L, Li Y, Sun Z, Zhou X
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120864
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120864
Effects of YAP1 on proliferation and differentiation of Hu sheep skeletal muscle satellite cells in vitro.
He M, Zhang W, Wang S, Ge L, Cao X, Wang S, Yuan Z, Lv X, Getachew T, Mwacharo JM, Haile A, Sun W
Animal biotechnology 2023 Dec;34(7):2691-2700
Animal biotechnology 2023 Dec;34(7):2691-2700
BMP4 participates in the pathogenesis of PCOS by regulating glucose metabolism and autophagy in granulosa cells under hyperandrogenic environment.
Gu R, Dai F, Xiang C, Chen J, Yang D, Tan W, Wang Z, Liu H, Cheng Y
The Journal of steroid biochemistry and molecular biology 2023 Dec;235:106410
The Journal of steroid biochemistry and molecular biology 2023 Dec;235:106410
ENO1 promotes liver carcinogenesis through YAP1-dependent arachidonic acid metabolism.
Sun L, Suo C, Zhang T, Shen S, Gu X, Qiu S, Zhang P, Wei H, Ma W, Yan R, Chen R, Jia W, Cao J, Zhang H, Gao P
Nature chemical biology 2023 Dec;19(12):1492-1503
Nature chemical biology 2023 Dec;19(12):1492-1503
Knockdown of Yap attenuates TAA-induced hepatic fibrosis by interaction with hedgehog signals.
Zhao Y, Wang H, He T, Ma B, Chen G, Tzeng C
Journal of cell communication and signaling 2023 Dec;17(4):1335-1354
Journal of cell communication and signaling 2023 Dec;17(4):1335-1354
Exosomes derived from mesenchymal stromal cells exert a therapeutic effect on hypoxia-induced pulmonary hypertension by modulating the YAP1/SPP1 signaling pathway.
Chen YX, Deng ZH, Xue-Gao, Qiang-Du, Juan-Yin, Chen GH, Li JG, Zhao YM, Zhang HT, Zhang GX, Qian JX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115816
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115816
IGF2BP1 enhances the stability of SIK2 mRNA through m(6)A modification to promote non-small cell lung cancer progression.
Xu Y, Xu L, Kong Y, Li K, Li J, Xu F, Liang S, Chen B
Biochemical and biophysical research communications 2023 Dec 3;684:149113
Biochemical and biophysical research communications 2023 Dec 3;684:149113
Hepatic Stellate Cell- and Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis.
Niu X, Meng Y, Cui J, Li R, Ding X, Niu B, Chang G, Xu N, Li G, Wang Y, Wang L
ACS nano 2023 Dec 12;17(23):23608-23625
ACS nano 2023 Dec 12;17(23):23608-23625
MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression.
Sun Y, Jin X, Meng J, Guo F, Chen T, Zhao X, Wu H, Ren D
The EMBO journal 2023 Dec 1;42(23):e114558
The EMBO journal 2023 Dec 1;42(23):e114558
O‑GlcNAcylation mediates endometrial cancer progression by regulating the Hippo‑YAP pathway.
Zhai L, Yang X, Dong J, Qian L, Gao Y, Lv Y, Chen L, Chen B, Zhou F
International journal of oncology 2023 Aug;63(2)
International journal of oncology 2023 Aug;63(2)
IGF2BP3/HIF1A/YAP signaling plays a role in driving acute-on-chronic liver failure through activating hepatocyte reprogramming.
Cheng K, Liu S, Li C, Zhao Y, Wang Q
Cellular signalling 2023 Aug;108:110727
Cellular signalling 2023 Aug;108:110727
SRSF3/AMOTL1 splicing axis promotes the tumorigenesis of nasopharyngeal carcinoma through regulating the nucleus translocation of YAP1.
Xu XC, Jiang JX, Zhou YQ, He S, Liu Y, Li YQ, Wei PP, Bei JX, Sun J, Luo CL
Cell death & disease 2023 Aug 9;14(8):511
Cell death & disease 2023 Aug 9;14(8):511
Coexisting cancer stem cells with heterogeneous gene amplifications, transcriptional profiles, and malignancy are isolated from single glioblastomas.
De Bacco F, Orzan F, Crisafulli G, Prelli M, Isella C, Casanova E, Albano R, Reato G, Erriquez J, D'Ambrosio A, Panero M, Dall'Aglio C, Casorzo L, Cominelli M, Pagani F, Melcarne A, Zeppa P, Altieri R, Morra I, Cassoni P, Garbossa D, Cassisa A, Bartolini A, Pellegatta S, Comoglio PM, Finocchiaro G, Poliani PL, Boccaccio C
Cell reports 2023 Aug 29;42(8):112816
Cell reports 2023 Aug 29;42(8):112816
Yes-associated protein inhibition ameliorates liver fibrosis and acute and chronic liver failure by decreasing ferroptosis and necroptosis.
Zhao W, Lei M, Li J, Zhang H, Zhang H, Han Y, Ba Z, Zhang M, Li D, Liu C
Heliyon 2023 Apr;9(4):e15075
Heliyon 2023 Apr;9(4):e15075
Synergistic Effect of Magneto-Mechanical Bioengineered Stem Cells and Magnetic Field to Alleviate Osteoporosis.
Yu C, Yang W, Yang L, Ye L, Sun R, Gu T, Ying X, Wang M, Tang R, Fan S, Yao S
ACS applied materials & interfaces 2023 Apr 26;15(16):19976-19988
ACS applied materials & interfaces 2023 Apr 26;15(16):19976-19988
Two-Pore-Domain Potassium Channel TREK-1 Mediates Pulmonary Fibrosis through Macrophage M2 Polarization and by Direct Promotion of Fibroblast Differentiation.
Zhang Y, Fu J, Han Y, Feng D, Yue S, Zhou Y, Luo Z
Biomedicines 2023 Apr 26;11(5)
Biomedicines 2023 Apr 26;11(5)
Chromatin Remodelling Molecule ARID1A Determines Metastatic Heterogeneity in Triple-Negative Breast Cancer by Competitively Binding to YAP.
Wang Y, Chen X, Qiao X, Xie Y, Guo D, Li B, Cao J, Tao Z, Hu X
Cancers 2023 Apr 25;15(9)
Cancers 2023 Apr 25;15(9)
LncRNA modulates Hippo-YAP signaling to reprogram iron metabolism.
He XY, Fan X, Qu L, Wang X, Jiang L, Sang LJ, Shi CY, Lin S, Yang JC, Yang ZZ, Lei K, Li JH, Ju HQ, Yan Q, Liu J, Wang F, Shao J, Xiong Y, Wang W, Lin A
Nature communications 2023 Apr 20;14(1):2253
Nature communications 2023 Apr 20;14(1):2253
KIAA1429-mediated m6A modification of CHST11 promotes progression of diffuse large B-cell lymphoma by regulating Hippo-YAP pathway.
Chen X, Lu T, Cai Y, Han Y, Ding M, Chu Y, Zhou X, Wang X
Cellular & molecular biology letters 2023 Apr 19;28(1):32
Cellular & molecular biology letters 2023 Apr 19;28(1):32
Lipid-Sensing Receptor FFAR4 Modulates Pulmonary Epithelial Homeostasis following Immunogenic Exposures Independently of the FFAR4 Ligand Docosahexaenoic Acid (DHA).
Sveiven SN, Anesko K, Morgan J, Nair MG, Nordgren TM
International journal of molecular sciences 2023 Apr 11;24(8)
International journal of molecular sciences 2023 Apr 11;24(8)
The role of YAP1 in survival prediction, immune modulation, and drug response: A pan-cancer perspective.
Hu X, Zhang Y, Yu H, Zhao Y, Sun X, Li Q, Wang Y
Frontiers in immunology 2022;13:1012173
Frontiers in immunology 2022;13:1012173
TiO(2) Nanotubes Promote Osteogenic Differentiation Through Regulation of Yap and Piezo1.
Kong K, Chang Y, Hu Y, Qiao H, Zhao C, Rong K, Zhang P, Zhang J, Zhai Z, Li H
Frontiers in bioengineering and biotechnology 2022;10:872088
Frontiers in bioengineering and biotechnology 2022;10:872088
Deacetylation of YAP1 Promotes the Resistance to Chemo- and Targeted Therapy in FLT3-ITD(+) AML Cells.
Feng P, Zhang J, Zhang J, Liu X, Pan L, Chen D, Ji M, Lu F, Li P, Li G, Sun T, Li J, Ye J, Ji C
Frontiers in cell and developmental biology 2022;10:842214
Frontiers in cell and developmental biology 2022;10:842214
CircPAK1 promotes the progression of hepatocellular carcinoma via modulation of YAP nucleus localization by interacting with 14-3-3ζ.
Hao X, Zhang Y, Shi X, Liu H, Zheng Z, Han G, Rong D, Zhang C, Tang W, Wang X
Journal of experimental & clinical cancer research : CR 2022 Sep 22;41(1):281
Journal of experimental & clinical cancer research : CR 2022 Sep 22;41(1):281
Targeting of MCL-1 in breast cancer-associated fibroblasts reverses their myofibroblastic phenotype and pro-invasive properties.
Bonneaud TL, Lefebvre CC, Nocquet L, Basseville A, Roul J, Weber H, Campone M, Juin PP, Souazé F
Cell death & disease 2022 Sep 14;13(9):787
Cell death & disease 2022 Sep 14;13(9):787
A derivant of ginsenoside CK and its inhibitory effect on hepatocellular carcinoma.
Zhang J, Tong Y, Lu X, Dong F, Ma X, Yin S, He Y, Liu Y, Liu Q, Fan D
Life sciences 2022 Sep 1;304:120698
Life sciences 2022 Sep 1;304:120698
Exploration of fetal growth restriction induced by vitamin D deficiency in rats via Hippo-YAP signaling pathway.
Wang J, Qiu F, Zhao Y, Gu S, Wang J, Zhang H
Placenta 2022 Oct;128:91-99
Placenta 2022 Oct;128:91-99
CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation.
Si M, Song Y, Wang X, Wang D, Liu X, Qu X, Song Z, Yu X
Cell & bioscience 2022 Oct 9;12(1):171
Cell & bioscience 2022 Oct 9;12(1):171
Promotion of Melanoma Cell Proliferation by Cyclic Straining through Regulatory Morphogenesis.
Huang S, Chen Z, Hou X, Han K, Xu B, Zhang M, Ding S, Wang Y, Yang Y
International journal of molecular sciences 2022 Oct 6;23(19)
International journal of molecular sciences 2022 Oct 6;23(19)
Caveolin-1 and Its Functional Peptide CSP7 Affect Silica-Induced Pulmonary Fibrosis by Regulating Fibroblast Glutaminolysis.
Li G, Xu Q, Cheng D, Sun W, Liu Y, Ma D, Wang Y, Zhou S, Ni C
Toxicological sciences : an official journal of the Society of Toxicology 2022 Oct 27;190(1):41-53
Toxicological sciences : an official journal of the Society of Toxicology 2022 Oct 27;190(1):41-53
RBCK1 is an endogenous inhibitor for triple negative breast cancer via hippo/YAP axis.
Li Z, Su P, Ding Y, Gao H, Yang H, Li X, Yang X, Xia Y, Zhang C, Fu M, Wang D, Zhang Y, Zhuo S, Zhu J, Zhuang T
Cell communication and signaling : CCS 2022 Oct 24;20(1):164
Cell communication and signaling : CCS 2022 Oct 24;20(1):164
Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and ameliorates organ fibrosis.
Wang L, Zhang Y, Ren Y, Yang X, Ben H, Zhao F, Yang S, Wang L, Qing J
European journal of pharmacology 2022 Oct 15;932:175241
European journal of pharmacology 2022 Oct 15;932:175241
mTORC1 signaling pathway integrates estrogen and growth factor to coordinate vaginal epithelial cells proliferation and differentiation.
Wan S, Sun Y, Fu J, Song H, Xiao Z, Yang Q, Wang S, Yu G, Feng P, Lv W, Luo L, Guan Z, Liu F, Zhou Q, Yin Z, Yang M
Cell death & disease 2022 Oct 11;13(10):862
Cell death & disease 2022 Oct 11;13(10):862
PSMA1 mediates tumor progression and poor prognosis of gastric carcinoma by deubiquitinating and stabilizing TAZ.
Yang Q, Lu Y, Shangguan J, Shu X
Cell death & disease 2022 Nov 23;13(11):989
Cell death & disease 2022 Nov 23;13(11):989
Liposomal UHRF1 siRNA shows lung fibrosis treatment potential through regulation of fibroblast activation.
Cheng D, Wang Y, Li Z, Xiong H, Sun W, Xi S, Zhou S, Liu Y, Ni C
JCI insight 2022 Nov 22;7(22)
JCI insight 2022 Nov 22;7(22)
Glucocorticoids rapidly promote YAP phosphorylation via the cAMP-PKA pathway to repress mouse cardiomyocyte proliferative potential.
Gan L, Li Q, Pan J, Chen L
Molecular and cellular endocrinology 2022 May 15;548:111615
Molecular and cellular endocrinology 2022 May 15;548:111615
Electrochemically derived nanographene oxide activates endothelial tip cells and promotes angiogenesis by binding endogenous lysophosphatidic acid.
Liu W, Luo H, Wei Q, Liu J, Wu J, Zhang Y, Chen L, Ren W, Shao L
Bioactive materials 2022 Mar;9:92-104
Bioactive materials 2022 Mar;9:92-104
FERM domain-containing protein 6 exerts a tumor-inhibiting role in thyroid cancer by antagonizing oncogenic YAP1.
Wang W, Zhao C, Quan F, Zhang P, Shao Y, Liu L
BioFactors (Oxford, England) 2022 Mar;48(2):428-441
BioFactors (Oxford, England) 2022 Mar;48(2):428-441
Polysaccharides from Platycodonis Radix ameliorated respiratory syncytial virus-induced epithelial cell apoptosis and inflammation through activation of miR-181a-mediated Hippo and SIRT1 pathways.
Li JJ, Liu ML, Lv JN, Chen RL, Ding K, He JQ
International immunopharmacology 2022 Mar;104:108510
International immunopharmacology 2022 Mar;104:108510
Novel insights into the mechanisms by which lncRNA HOTAIR regulates migration and invasion in HeLa cells.
Zheng P, Wu Y, Chen Y, Chen Z, Zhang T
Cell cycle (Georgetown, Tex.) 2022 Mar-Mar;21(6):602-617
Cell cycle (Georgetown, Tex.) 2022 Mar-Mar;21(6):602-617
Mechanical control of nuclear import by Importin-7 is regulated by its dominant cargo YAP.
García-García M, Sánchez-Perales S, Jarabo P, Calvo E, Huyton T, Fu L, Ng SC, Sotodosos-Alonso L, Vázquez J, Casas-Tintó S, Görlich D, Echarri A, Del Pozo MA
Nature communications 2022 Mar 4;13(1):1174
Nature communications 2022 Mar 4;13(1):1174
Restraint of chaperonin containing T-complex protein-1 subunit 3 has antitumor roles in non-small cell lung cancer via affection of YAP1.
Shi H, Zhang Y, Wang Y, Fang P, Liu Y, Li W
Toxicology and applied pharmacology 2022 Mar 15;439:115926
Toxicology and applied pharmacology 2022 Mar 15;439:115926
WISP2/CCN5 Suppresses Vasculogenic Mimicry through Inhibition of YAP/TAZ Signaling in Breast Cancer Cells.
Ferrand N, Fert A, Morichon R, Radosevic-Robin N, Zaoui M, Sabbah M
Cancers 2022 Mar 14;14(6)
Cancers 2022 Mar 14;14(6)
Fusobacterium nucleatum reduces METTL3-mediated m(6)A modification and contributes to colorectal cancer metastasis.
Chen S, Zhang L, Li M, Zhang Y, Sun M, Wang L, Lin J, Cui Y, Chen Q, Jin C, Li X, Wang B, Chen H, Zhou T, Wang L, Hsu CH, Zhuo W
Nature communications 2022 Mar 10;13(1):1248
Nature communications 2022 Mar 10;13(1):1248
SIRPγ-expressing cancer stem-like cells promote immune escape of lung cancer via Hippo signaling.
Xu C, Jin G, Wu H, Cui W, Wang YH, Manne RK, Wang G, Zhang W, Zhang X, Han F, Cai Z, Pan BS, Hsu CC, Liu Y, Zhang A, Long J, Zou H, Wang S, Ma X, Duan J, Wang B, Liu W, Lan H, Xiong Q, Xue G, Chen Z, Xu Z, Furth ME, Haigh Molina S, Lu Y, Xie D, Bian XW, Lin HK
The Journal of clinical investigation 2022 Mar 1;132(5)
The Journal of clinical investigation 2022 Mar 1;132(5)
Divergent transcriptional regulation of astrocyte reactivity across disorders.
Burda JE, O'Shea TM, Ao Y, Suresh KB, Wang S, Bernstein AM, Chandra A, Deverasetty S, Kawaguchi R, Kim JH, McCallum S, Rogers A, Wahane S, Sofroniew MV
Nature 2022 Jun;606(7914):557-564
Nature 2022 Jun;606(7914):557-564
A myogenic niche with a proper mechanical stress environment improves abdominal wall muscle repair by modulating immunity and preventing fibrosis.
Wang S, Yan H, Fang B, Gu C, Guo J, Qiu P, Song N, Xu W, Zhang J, Lin X, Fang X
Biomaterials 2022 Jun;285:121519
Biomaterials 2022 Jun;285:121519
MicroRNA-122-5p Aggravates Angiotensin II-Mediated Myocardial Fibrosis and Dysfunction in Hypertensive Rats by Regulating the Elabela/Apelin-APJ and ACE2-GDF15-Porimin Signaling.
Song J, Zhang Z, Dong Z, Liu X, Liu Y, Li X, Xu Y, Guo Y, Wang N, Zhang M, Chen Y, Jin H, Zhong J
Journal of cardiovascular translational research 2022 Jun;15(3):535-547
Journal of cardiovascular translational research 2022 Jun;15(3):535-547
The proteasome-dependent degradation of ALKBH5 regulates ECM deposition in PM(2.5) exposure-induced pulmonary fibrosis of mice.
Zhang Y, Liu Q, Ning J, Jiang T, Kang A, Li L, Pang Y, Zhang B, Huang X, Wang Q, Bao L, Niu Y, Zhang R
Journal of hazardous materials 2022 Jun 15;432:128655
Journal of hazardous materials 2022 Jun 15;432:128655
Centella asiatica (L.) Urb. attenuates cardiac hypertrophy and improves heart function through multi-level mechanisms revealed by systems pharmacology.
Ding B, Niu W, Wang S, Zhang F, Wang H, Chen X, Chen S, Ma S, Kang W, Wang M, Li L, Xiao W, Guo Z, Wang Y
Journal of ethnopharmacology 2022 Jun 12;291:115106
Journal of ethnopharmacology 2022 Jun 12;291:115106
YAP/TAZ activity in stromal cells prevents ageing by controlling cGAS-STING.
Sladitschek-Martens HL, Guarnieri A, Brumana G, Zanconato F, Battilana G, Xiccato RL, Panciera T, Forcato M, Bicciato S, Guzzardo V, Fassan M, Ulliana L, Gandin A, Tripodo C, Foiani M, Brusatin G, Cordenonsi M, Piccolo S
Nature 2022 Jul;607(7920):790-798
Nature 2022 Jul;607(7920):790-798
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner.
Yu T, Liu Y, Xue J, Sun X, Zhu D, Ma L, Guo Y, Jin T, Cao H, Chen Y, Zhu T, Li X, Liang H, Du Z, Shan H
Cell death discovery 2022 Jul 9;8(1):312
Cell death discovery 2022 Jul 9;8(1):312
Single-cell atlas of keratoconus corneas revealed aberrant transcriptional signatures and implicated mechanical stretch as a trigger for keratoconus pathogenesis.
Dou S, Wang Q, Zhang B, Wei C, Wang H, Liu T, Duan H, Jiang H, Liu M, Qi X, Zhou Q, Xie L, Shi W, Gao H
Cell discovery 2022 Jul 12;8(1):66
Cell discovery 2022 Jul 12;8(1):66
miR-1307-5p suppresses proliferation and tumorigenesis of bladder cancer via targeting MDM4 and the Hippo signaling pathway.
Huang W, Zhang C, Xiong S, Zhou X, Wang G, Guo J
Discover oncology 2022 Jul 1;13(1):57
Discover oncology 2022 Jul 1;13(1):57
The function of Nucleoporin 37 on mouse oocyte maturation and preimplantation embryo development.
Guo Q, Liu Q, Wang N, Wang J, Sun A, Qiao J, Yan L
Journal of assisted reproduction and genetics 2022 Jan;39(1):107-116
Journal of assisted reproduction and genetics 2022 Jan;39(1):107-116
Linc01133 contributes to gastric cancer growth by enhancing YES1-dependent YAP1 nuclear translocation via sponging miR-145-5p.
Sun Y, Tian Y, He J, Tian Y, Zhang G, Zhao R, Zhu WJ, Gao P
Cell death & disease 2022 Jan 11;13(1):51
Cell death & disease 2022 Jan 11;13(1):51
RNF6 promotes the migration and invasion of breast cancer by promoting the ubiquitination and degradation of MST1.
Huang Y, Zou Y, Jie Z
Experimental and therapeutic medicine 2022 Feb;23(2):118
Experimental and therapeutic medicine 2022 Feb;23(2):118
Profiling and functional characterization of maternal mRNA translation during mouse maternal-to-zygotic transition.
Zhang C, Wang M, Li Y, Zhang Y
Science advances 2022 Feb 4;8(5):eabj3967
Science advances 2022 Feb 4;8(5):eabj3967
Acquired temozolomide resistance in MGMT(low) gliomas is associated with regulation of homologous recombination repair by ROCK2.
Zhang X, Li T, Yang M, Du Q, Wang R, Fu B, Tan Y, Cao M, Chen Y, Wang Q, Hu R
Cell death & disease 2022 Feb 10;13(2):138
Cell death & disease 2022 Feb 10;13(2):138
USP36 facilitates esophageal squamous carcinoma progression via stabilizing YAP.
Zhang W, Luo J, Xiao Z, Zang Y, Li X, Zhou Y, Zhou J, Tian Z, Zhu J, Zhao X
Cell death & disease 2022 Dec 5;13(12):1021
Cell death & disease 2022 Dec 5;13(12):1021
Heterogeneous matrix stiffness regulates the cancer stem-like cell phenotype in hepatocellular carcinoma.
Wei J, Yao J, Yang C, Mao Y, Zhu D, Xie Y, Liu P, Yan M, Ren L, Lin Y, Zheng Q, Li X
Journal of translational medicine 2022 Dec 3;20(1):555
Journal of translational medicine 2022 Dec 3;20(1):555
Effect of hypoxia on HIF-1α/MDR1/VEGF expression in gastric cancer cells treated with 5-fluorouracil.
Wang L, Xing W, Qi J, Lu Y, Xiang L, Zhou Y
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2022 Dec 28;47(12):1629-1636
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 2022 Dec 28;47(12):1629-1636
Resveratrol inhibits proliferation and induces apoptosis via the Hippo/YAP pathway in human colon cancer cells.
Qin X, Luo H, Deng Y, Yao X, Zhang J, He B
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 1):197-204
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 1):197-204
Analysis of disordered abrasive scratches on titanium surfaces and their impact on nuclear translocation of yes-associated protein.
Migita S, Wakabayashi K
Scientific reports 2022 Dec 15;12(1):21705
Scientific reports 2022 Dec 15;12(1):21705
Knockdown of HSP110 attenuates hypoxia-induced pulmonary hypertension in mice through suppression of YAP/TAZ-TEAD4 pathway.
Liu H, Zhang S, Liu Y, Ma J, Chen W, Yin T, Li T, Liang B, Tao L
Respiratory research 2022 Aug 19;23(1):209
Respiratory research 2022 Aug 19;23(1):209
miR-596-3p suppresses brain metastasis of non-small cell lung cancer by modulating YAP1 and IL-8.
Li C, Zheng H, Xiong J, Huang Y, Li H, Jin H, Ai S, Wang Y, Su T, Sun G, Xiao X, Fu T, Wang Y, Gao X, Liang P
Cell death & disease 2022 Aug 12;13(8):699
Cell death & disease 2022 Aug 12;13(8):699
MiR-125b enhances doxorubicin-induced cardiotoxicity by suppressing the nucleus-cytoplasmic translocation of YAP via targeting STARD13.
Jin X, Yu W, Ye P
Environmental toxicology 2022 Apr;37(4):730-740
Environmental toxicology 2022 Apr;37(4):730-740
SOX13/TRIM11/YAP axis promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer.
Tang J, Tian Z, Liao X, Wu G
International journal of biological sciences 2021;17(2):417-429
International journal of biological sciences 2021;17(2):417-429
PADI6 Regulates Trophoblast Cell Migration-Invasion Through the Hippo/YAP1 Pathway in Hydatidiform Moles.
Huang B, Zhao Y, Zhou L, Gong T, Feng J, Han P, Qian J
Journal of inflammation research 2021;14:3489-3500
Journal of inflammation research 2021;14:3489-3500
Expression and Functional Relevance of ANXA1 in Hypopharyngeal Carcinoma with Lymph Node Metastasis.
Li L, Wang Z, Lu T, Li Y, Pan M, Yu D, Hu G
OncoTargets and therapy 2021;14:1387-1399
OncoTargets and therapy 2021;14:1387-1399
Involvement of the TGF-β Signaling Pathway in the Development of YAP-Driven Osteosarcoma Lung Metastasis.
Morice S, Danieau G, Tesfaye R, Mullard M, Brion R, Dupuy M, Ory B, Brounais-Le Royer B, Corre I, Redini F, Verrecchia F
Frontiers in oncology 2021;11:765711
Frontiers in oncology 2021;11:765711
Traditional Chinese medicine Yiqi Huoxue recipe attenuates hepatic fibrosis via YAP/TAZ signaling.
Zhao W, Zhang X, Hou M, Zhang Y, Tang Y, Li L, Dong S, Liu L, Zhao D, Li W, Nan Y
Histology and histopathology 2021 Sep;36(9):967-979
Histology and histopathology 2021 Sep;36(9):967-979
PPP1CA/YAP/GS/Gln/mTORC1 pathway activates retinal Müller cells during diabetic retinopathy.
Guo Y, Cang X, Zhu L, Zhu M, Li A, Wang Z, Zhang Y, Wang X, Song E
Experimental eye research 2021 Sep;210:108703
Experimental eye research 2021 Sep;210:108703
MiR-200c-3p promotes ox-LDL-induced endothelial to mesenchymal transition in human umbilical vein endothelial cells through SMAD7/YAP pathway.
Mao Y, Jiang L
The journal of physiological sciences : JPS 2021 Sep 15;71(1):30
The journal of physiological sciences : JPS 2021 Sep 15;71(1):30
Reduced DAPK1 Expression Promotes Stem Cell-Like Characteristics of Prostate Cancer Cells by Activating ZEB1 via Hippo/YAP Signaling Pathway.
Nong S, Wei Z, Wang Z, Ma L, Guan Y, Ni J
Stem cells and development 2021 Sep 15;30(18):934-945
Stem cells and development 2021 Sep 15;30(18):934-945
SGLT2 promotes pancreatic cancer progression by activating the Hippo signaling pathway via the hnRNPK-YAP1 axis.
Ren D, Sun Y, Zhang D, Li D, Liu Z, Jin X, Wu H
Cancer letters 2021 Oct 28;519:277-288
Cancer letters 2021 Oct 28;519:277-288
Identification of YAP1 as a novel downstream effector of the FGF2/STAT3 pathway in the pathogenesis of renal tubulointerstitial fibrosis.
Li X, Zhang F, Qu L, Xie Y, Ruan Y, Guo Z, Mao Y, Zou Q, Shi M, Xiao Y, Wang Y, Zhou Y, Guo B
Journal of cellular physiology 2021 Nov;236(11):7655-7671
Journal of cellular physiology 2021 Nov;236(11):7655-7671
Delineating the heterogeneity of matrix-directed differentiation toward soft and stiff tissue lineages via single-cell profiling.
Brielle S, Bavli D, Motzik A, Kan-Tor Y, Sun X, Kozulin C, Avni B, Ram O, Buxboim A
Proceedings of the National Academy of Sciences of the United States of America 2021 May 11;118(19)
Proceedings of the National Academy of Sciences of the United States of America 2021 May 11;118(19)
Overexpressed WDR3 induces the activation of Hippo pathway by interacting with GATA4 in pancreatic cancer.
Su W, Zhu S, Chen K, Yang H, Tian M, Fu Q, Shi G, Feng S, Ren D, Jin X, Yang C
Journal of experimental & clinical cancer research : CR 2021 Mar 1;40(1):88
Journal of experimental & clinical cancer research : CR 2021 Mar 1;40(1):88
Melatonin promotes cardiomyocyte proliferation and heart repair in mice with myocardial infarction via miR-143-3p/Yap/Ctnnd1 signaling pathway.
Ma WY, Song RJ, Xu BB, Xu Y, Wang XX, Sun HY, Li SN, Liu SZ, Yu MX, Yang F, Ye DY, Gong R, Han ZB, Yu Y, Bamba D, Wang N, Pan ZW, Cai BZ
Acta pharmacologica Sinica 2021 Jun;42(6):921-931
Acta pharmacologica Sinica 2021 Jun;42(6):921-931
Long non-coding RNA muskelin 1 antisense RNA (MKLN1-AS) is a potential diagnostic and prognostic biomarker and therapeutic target for hepatocellular carcinoma.
Guo C, Zhou S, Yi W, Yang P, Li O, Liu J, Peng C
Experimental and molecular pathology 2021 Jun;120:104638
Experimental and molecular pathology 2021 Jun;120:104638
Importance of Potential New Biomarkers in Patient with Serouse Ovarian Cancer.
Cymbaluk-Płoska A, Chudecka K, Chudecka-Głaz A, Piotrowska K, Kwiatkowski S, Tarnowski M
Diagnostics (Basel, Switzerland) 2021 Jun 3;11(6)
Diagnostics (Basel, Switzerland) 2021 Jun 3;11(6)
Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development.
Pocaterra A, Scattolin G, Romani P, Ament C, Ribback S, Chen X, Evert M, Calvisi DF, Dupont S
Communications biology 2021 Jun 21;4(1):763
Communications biology 2021 Jun 21;4(1):763
MINDY1 promotes bladder cancer progression by stabilizing YAP.
Luo Y, Zhou J, Tang J, Zhou F, He Z, Liu T, Liu T
Cancer cell international 2021 Jul 27;21(1):395
Cancer cell international 2021 Jul 27;21(1):395
Prototypical oncogene family Myc defines unappreciated distinct lineage states of small cell lung cancer.
Patel AS, Yoo S, Kong R, Sato T, Sinha A, Karam S, Bao L, Fridrikh M, Emoto K, Nudelman G, Powell CA, Beasley MB, Zhu J, Watanabe H
Science advances 2021 Jan;7(5)
Science advances 2021 Jan;7(5)
Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis.
Pastushenko I, Mauri F, Song Y, de Cock F, Meeusen B, Swedlund B, Impens F, Van Haver D, Opitz M, Thery M, Bareche Y, Lapouge G, Vermeersch M, Van Eycke YR, Balsat C, Decaestecker C, Sokolow Y, Hassid S, Perez-Bustillo A, Agreda-Moreno B, Rios-Buceta L, Jaen P, Redondo P, Sieira-Gil R, Millan-Cayetano JF, Sanmatrtin O, D'Haene N, Moers V, Rozzi M, Blondeau J, Lemaire S, Scozzaro S, Janssens V, De Troya M, Dubois C, Pérez-Morga D, Salmon I, Sotiriou C, Helmbacher F, Blanpain C
Nature 2021 Jan;589(7842):448-455
Nature 2021 Jan;589(7842):448-455
AMOTL2 inhibits JUN Thr239 dephosphorylation by binding PPP2R2A to suppress the proliferation in non-small cell lung cancer cells.
Cui R, Jiang N, Zhang M, Du S, Ou H, Ge R, Ma D, Zhang J
Biochimica et biophysica acta. Molecular cell research 2021 Jan;1868(1):118858
Biochimica et biophysica acta. Molecular cell research 2021 Jan;1868(1):118858
S1P induces proliferation of pulmonary artery smooth muscle cells by promoting YAP-induced Notch3 expression and activation.
Wang J, Yan X, Feng W, Wang Q, Shi W, Chai L, Zhang Q, Chen Y, Liu J, Qu Z, Xie X, Li M
The Journal of biological chemistry 2021 Jan-Jun;296:100599
The Journal of biological chemistry 2021 Jan-Jun;296:100599
Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway.
Luo C, Sun H, Peng J, Gao C, Bao L, Ji R, Zhang C, Zhu W, Jin Y
Phytotherapy research : PTR 2021 Feb;35(2):1010-1022
Phytotherapy research : PTR 2021 Feb;35(2):1010-1022
Angiomotin-like 1 plays a tumor-promoting role in glioma by enhancing the activation of YAP1 signaling.
Xu G, Seng Z, Zhang M, Qu J
Environmental toxicology 2021 Dec;36(12):2500-2511
Environmental toxicology 2021 Dec;36(12):2500-2511
Loss of m(6)A methyltransferase METTL3 promotes heart regeneration and repair after myocardial injury.
Gong R, Wang X, Li H, Liu S, Jiang Z, Zhao Y, Yu Y, Han Z, Yu Y, Dong C, Li S, Xu B, Zhang W, Wang N, Li X, Gao X, Yang F, Bamba D, Ma W, Liu Y, Cai B
Pharmacological research 2021 Dec;174:105845
Pharmacological research 2021 Dec;174:105845
Inhibiting roles of FOXA2 in liver cancer cell migration and invasion by transcriptionally suppressing microRNA-103a-3p and activating the GREM2/LATS2/YAP axis.
Ma G, Chen J, Wei T, Wang J, Chen W
Cytotechnology 2021 Aug;73(4):523-537
Cytotechnology 2021 Aug;73(4):523-537
Uremic toxin indoxyl sulfate promotes proinflammatory macrophage activation by regulation of β-catenin and YAP pathways.
Li Y, Yan J, Wang M, Lv J, Yan F, Chen J
Journal of molecular histology 2021 Apr;52(2):197-205
Journal of molecular histology 2021 Apr;52(2):197-205
Circ-ITCH sponges miR-214 to promote the osteogenic differentiation in osteoporosis via upregulating YAP1.
Zhong D, Xu GZ, Wu JZ, Liu H, Tang JY, Wang CG
Cell death & disease 2021 Apr 1;12(4):340
Cell death & disease 2021 Apr 1;12(4):340
Retinal dehydrogenase 5 (RHD5) attenuates metastasis via regulating HIPPO/YAP signaling pathway in Hepatocellular Carcinoma.
Hu H, Xu L, Luo SJ, Xiang T, Chen Y, Cao ZR, Zhang YJ, Mo Z, Wang Y, Meng DF, Yu L, Lin LZ, Zhang SJ
International journal of medical sciences 2020;17(13):1897-1908
International journal of medical sciences 2020;17(13):1897-1908
Calcipotriol Inhibits NLRP3 Signal Through YAP1 Activation to Alleviate Cholestatic Liver Injury and Fibrosis.
Wang X, Wang G, Qu J, Yuan Z, Pan R, Li K
Frontiers in pharmacology 2020;11:200
Frontiers in pharmacology 2020;11:200
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism.
Xie T, Wang C, Jin Y, Meng Q, Liu Q, Wu J, Sun H
Frontiers in pharmacology 2020;11:1034
Frontiers in pharmacology 2020;11:1034
CSRP2 suppresses colorectal cancer progression via p130Cas/Rac1 axis-meditated ERK, PAK, and HIPPO signaling pathways.
Chen L, Long X, Duan S, Liu X, Chen J, Lan J, Liu X, Huang W, Geng J, Zhou J
Theranostics 2020;10(24):11063-11079
Theranostics 2020;10(24):11063-11079
FAM83A Promotes Lung Cancer Progression by Regulating the Wnt and Hippo Signaling Pathways and Indicates Poor Prognosis.
Zheng YW, Li ZH, Lei L, Liu CC, Wang Z, Fei LR, Yang MQ, Huang WJ, Xu HT
Frontiers in oncology 2020;10:180
Frontiers in oncology 2020;10:180
YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways.
Liu J, Gao M, Xu S, Chen Y, Wu K, Liu H, Wang J, Yang X, Wang J, Liu W, Bao X, Chen J
Cell reports 2020 Sep 8;32(10):108120
Cell reports 2020 Sep 8;32(10):108120
Genome-wide cooperation of EMT transcription factor ZEB1 with YAP and AP-1 in breast cancer.
Feldker N, Ferrazzi F, Schuhwerk H, Widholz SA, Guenther K, Frisch I, Jakob K, Kleemann J, Riegel D, Bönisch U, Lukassen S, Eccles RL, Schmidl C, Stemmler MP, Brabletz T, Brabletz S
The EMBO journal 2020 Sep 1;39(17):e103209
The EMBO journal 2020 Sep 1;39(17):e103209
MiR-375-3p alleviates the severity of inflammation through targeting YAP1/LEKTI pathway in HaCaT cells.
Cheng S, Di Z, Hirman AR, Zheng H, Duo L, Zhai Q, Xu J
Bioscience, biotechnology, and biochemistry 2020 Oct;84(10):2005-2013
Bioscience, biotechnology, and biochemistry 2020 Oct;84(10):2005-2013
Eva-1 homolog A promotes papillary thyroid cancer progression and epithelial-mesenchymal transition via the Hippo signalling pathway.
Lin BY, Wen JL, Zheng C, Lin LZ, Chen CZ, Qu JM
Journal of cellular and molecular medicine 2020 Nov;24(22):13070-13080
Journal of cellular and molecular medicine 2020 Nov;24(22):13070-13080
Interaction of BACH2 with FUS promotes malignant progression of glioma cells via the TSLNC8-miR-10b-5p-WWC3 pathway.
Yang Y, Liu X, Zheng J, Xue Y, Liu L, Ma J, Wang P, Yang C, Wang D, Shao L, Ruan X, Liu Y
Molecular oncology 2020 Nov;14(11):2936-2959
Molecular oncology 2020 Nov;14(11):2936-2959
Vitamin D3 analogue facilitates epithelial wound healing through promoting epithelial-mesenchymal transition via the Hippo pathway.
Wang D, Lin L, Lei K, Zeng J, Luo J, Yin Y, Li Y, Zhang L, Nie X, Zuo D, Sun L
Journal of dermatological science 2020 Nov;100(2):120-128
Journal of dermatological science 2020 Nov;100(2):120-128
MiR-103a-3p promotes tumour glycolysis in colorectal cancer via hippo/YAP1/HIF1A axis.
Sun Z, Zhang Q, Yuan W, Li X, Chen C, Guo Y, Shao B, Dang Q, Zhou Q, Wang Q, Wang G, Liu J, Kan Q
Journal of experimental & clinical cancer research : CR 2020 Nov 20;39(1):250
Journal of experimental & clinical cancer research : CR 2020 Nov 20;39(1):250
Gut microbiota transplantation from db/db mice induces diabetes-like phenotypes and alterations in Hippo signaling in pseudo germ-free mice.
Yu F, Jiang R, Han W, Zhan G, Xu X, Jiang X, Wang L, Xiang S, Zhou Q, Liu C, Zhu B, Hua F, Yang C
Aging 2020 Nov 20;12(23):24156-24167
Aging 2020 Nov 20;12(23):24156-24167
Regulation of Hippo-YAP signaling by insulin-like growth factor-1 receptor in the tumorigenesis of diffuse large B-cell lymphoma.
Zhou X, Chen N, Xu H, Zhou X, Wang J, Fang X, Zhang Y, Li Y, Yang J, Wang X
Journal of hematology & oncology 2020 Jun 16;13(1):77
Journal of hematology & oncology 2020 Jun 16;13(1):77
Targeting LncDACH1 promotes cardiac repair and regeneration after myocardium infarction.
Cai B, Ma W, Wang X, Sukhareva N, Hua B, Zhang L, Xu J, Li X, Li S, Liu S, Yu M, Xu Y, Song R, Xu B, Yang F, Han Z, Ding F, Huang Q, Yu Y, Zhao Y, Wang J, Bamba D, Zagidullin N, Li F, Tian Y, Pan Z, Yang B
Cell death and differentiation 2020 Jul;27(7):2158-2175
Cell death and differentiation 2020 Jul;27(7):2158-2175
Effect of Maternal Age on Hippo Pathway Related Gene Expressions and Protein Localization Pattern in Human Embryos.
Gharanfoli S, Shahverdi A, Dalman A, Ghaznavi P, Alipour H, Eftekhari-Yazdi P
Cell journal 2020 Jul;22(Suppl 1):74-80
Cell journal 2020 Jul;22(Suppl 1):74-80
gga-microRNA-375 negatively regulates the cell cycle and proliferation by targeting Yes-associated protein 1 in DF-1 cells.
Zhang X, Liao Z, Wu Y, Yan Y, Chen S, Lin S, Chen F, Xie Q
Experimental and therapeutic medicine 2020 Jul;20(1):530-542
Experimental and therapeutic medicine 2020 Jul;20(1):530-542
MALAT1 knockdown inhibits hypopharyngeal squamous cell carcinoma malignancy by targeting microRNA-194.
Wang H, Wang F, Ouyang W, Jiang X, Li W
Oncology letters 2020 Jul;20(1):173-182
Oncology letters 2020 Jul;20(1):173-182
Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties.
Panciera T, Citron A, Di Biagio D, Battilana G, Gandin A, Giulitti S, Forcato M, Bicciato S, Panzetta V, Fusco S, Azzolin L, Totaro A, Dei Tos AP, Fassan M, Vindigni V, Bassetto F, Rosato A, Brusatin G, Cordenonsi M, Piccolo S
Nature materials 2020 Jul;19(7):797-806
Nature materials 2020 Jul;19(7):797-806
PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.
Yu W, Hua Y, Qiu H, Hao J, Zou K, Li Z, Hu S, Guo P, Chen M, Sui S, Xiong Y, Li F, Lu J, Guo W, Luo G, Deng W
Cell death & disease 2020 Jul 6;11(7):506
Cell death & disease 2020 Jul 6;11(7):506
Long noncoding RNA CASC21 exerts an oncogenic role in colorectal cancer through regulating miR-7-5p/YAP1 axis.
Zheng Y, Nie P, Xu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109628
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109628
Retinal blood vessel-origin yes-associated protein (YAP) governs astrocytic maturation via leukaemia inhibitory factor (LIF).
Ai LQ, Yuan RD, Chen X, Liu YJ, Liu WY, Zhu JY, Zhang Z, Yan J, Chen CL, Lin S, Ye J
Cell proliferation 2020 Feb;53(2):e12757
Cell proliferation 2020 Feb;53(2):e12757
RETRACTED: METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing.
Chen X, Xu M, Xu X, Zeng K, Liu X, Sun L, Pan B, He B, Pan Y, Sun H, Xia X, Wang S
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):599-612
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Feb 5;28(2):599-612
Chondroitin synthase-3 regulates nucleus pulposus degeneration through actin-induced YAP signaling.
Wei L, Cao P, Xu C, Zhong H, Wang X, Bai M, Hu B, Wang R, Liu N, Tian Y, Chen H, Li J, Yuan W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16581-16600
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16581-16600
Role of RBM3 in the regulation of cell proliferation in hepatocellular carcinoma.
Miao X, Zhang N
Experimental and molecular pathology 2020 Dec;117:104546
Experimental and molecular pathology 2020 Dec;117:104546
Arsenic nano complex induced degradation of YAP sensitized ESCC cancer cells to radiation and chemotherapy.
Zhou W, Liu M, Li X, Zhang P, Li J, Zhao Y, Sun G, Mao W
Cell & bioscience 2020 Dec 22;10(1):146
Cell & bioscience 2020 Dec 22;10(1):146
The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth.
Morice S, Mullard M, Brion R, Dupuy M, Renault S, Tesfaye R, Brounais-Le Royer B, Ory B, Redini F, Verrecchia F
Cancers 2020 Dec 20;12(12)
Cancers 2020 Dec 20;12(12)
Mechanisms of stretch-mediated skin expansion at single-cell resolution.
Aragona M, Sifrim A, Malfait M, Song Y, Van Herck J, Dekoninck S, Gargouri S, Lapouge G, Swedlund B, Dubois C, Baatsen P, Vints K, Han S, Tissir F, Voet T, Simons BD, Blanpain C
Nature 2020 Aug;584(7820):268-273
Nature 2020 Aug;584(7820):268-273
TRIB3 confers radiotherapy resistance in esophageal squamous cell carcinoma by stabilizing TAZ.
Zhou S, Liu S, Lin C, Li Y, Ye L, Wu X, Jian Y, Dai Y, Ouyang Y, Zhao L, Liu M, Song L, Xi M
Oncogene 2020 Apr;39(18):3710-3725
Oncogene 2020 Apr;39(18):3710-3725
Estradiol-17β regulates proliferation and apoptosis of sheep endometrial epithelial cells by regulating the relative abundance of YAP1.
An SY, Gao XX, Wang ZB, Liang YX, Wang ST, Xiao SH, Xia JT, You PH, Wang F, Zhang GM
Animal reproduction science 2020 Apr;215:106328
Animal reproduction science 2020 Apr;215:106328
miR-25 Promotes Cell Proliferation, Migration, and Invasion of Non-Small-Cell Lung Cancer by Targeting the LATS2/YAP Signaling Pathway.
Wu T, Hu H, Zhang T, Jiang L, Li X, Liu S, Zheng C, Yan G, Chen W, Ning Y, Li Y, Lu Z
Oxidative medicine and cellular longevity 2019;2019:9719723
Oxidative medicine and cellular longevity 2019;2019:9719723
Jiedu Sangen Decoction Inhibits the Invasion and Metastasis of Colorectal Cancer Cells by Regulating EMT through the Hippo Signaling Pathway.
Yuan L, Zhou M, Wasan HS, Zhang K, Li Z, Guo K, Shen F, Shen M, Ruan S
Evidence-based complementary and alternative medicine : eCAM 2019;2019:1431726
Evidence-based complementary and alternative medicine : eCAM 2019;2019:1431726
Downregulation of CENPK suppresses hepatocellular carcinoma malignant progression through regulating YAP1.
Wang J, Li H, Xia C, Yang X, Dai B, Tao K, Dou K
OncoTargets and therapy 2019;12:869-882
OncoTargets and therapy 2019;12:869-882
Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1.
Liu K, Du S, Gao P, Zheng J
Journal of Cancer 2019;10(18):4196-4207
Journal of Cancer 2019;10(18):4196-4207
Tumor Suppressor LKB1 inhibits both the mRNA Expression and the Amplification of hTERC by the Phosphorylation of YAP in Lung Cancer Cells.
He L, Wu MZ, Wang XB, Qiu XS, Wang EH, Wu GP
Journal of Cancer 2019;10(16):3632-3638
Journal of Cancer 2019;10(16):3632-3638
miR-375-3p suppresses tumorigenesis and partially reverses chemoresistance by targeting YAP1 and SP1 in colorectal cancer cells.
Xu X, Chen X, Xu M, Liu X, Pan B, Qin J, Xu T, Zeng K, Pan Y, He B, Sun H, Sun L, Wang S
Aging 2019 Sep 22;11(18):7357-7385
Aging 2019 Sep 22;11(18):7357-7385
Essential Oil from Pinus Koraiensis Pinecones Inhibits Gastric Cancer Cells via the HIPPO/YAP Signaling Pathway.
Zhang Y, Xin C, Qiu J, Wang Z
Molecules (Basel, Switzerland) 2019 Oct 25;24(21)
Molecules (Basel, Switzerland) 2019 Oct 25;24(21)
Differential Levels of Hippo Signaling in Selected Brain and Peripheral Tissues in Streptozotocin-Induced Cognitive Dysfunction in Mice.
Yu F, Han W, Zhan G, Li S, Jiang X, Xiang S, Zhu B, Yang L, Hua D, Luo A, Hua F, Yang C
Neuroscience 2019 Nov 21;421:48-58
Neuroscience 2019 Nov 21;421:48-58
F-actin dynamics regulates mammalian organ growth and cell fate maintenance.
Pocaterra A, Santinon G, Romani P, Brian I, Dimitracopoulos A, Ghisleni A, Carnicer-Lombarte A, Forcato M, Braghetta P, Montagner M, Galuppini F, Aragona M, Pennelli G, Bicciato S, Gauthier N, Franze K, Dupont S
Journal of hepatology 2019 Jul;71(1):130-142
Journal of hepatology 2019 Jul;71(1):130-142
LncRNA PFAR contributes to fibrogenesis in lung fibroblasts through competitively binding to miR-15a.
Sun J, Su W, Zhao X, Shan T, Jin T, Guo Y, Li C, Li R, Zhou Y, Shan H, Sun X, Liang H
Bioscience reports 2019 Jul 31;39(7)
Bioscience reports 2019 Jul 31;39(7)
Circular RNA Vav3 sponges gga-miR-375 to promote epithelial-mesenchymal transition.
Zhang X, Yan Y, Lin W, Li A, Zhang H, Lei X, Dai Z, Li X, Li H, Chen W, Chen F, Ma J, Xie Q
RNA biology 2019 Jan;16(1):118-132
RNA biology 2019 Jan;16(1):118-132
The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae.
Rausch V, Bostrom JR, Park J, Bravo IR, Feng Y, Hay DC, Link BA, Hansen CG
Current biology : CB 2019 Jan 21;29(2):242-255.e6
Current biology : CB 2019 Jan 21;29(2):242-255.e6
Fufang Xueshuantong protects retinal vascular endothelial cells from high glucose by targeting YAP.
Xing W, Song Y, Li H, Wang Z, Wu Y, Li C, Wang Y, Liu Y, Wang W, Han J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109470
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109470
Yes-associated protein regulates podocyte cell cycle re-entry and dedifferentiation in adriamycin-induced nephropathy.
Xie K, Xu C, Zhang M, Wang M, Min L, Qian C, Wang Q, Ni Z, Mou S, Dai H, Pang H, Gu L
Cell death & disease 2019 Dec 4;10(12):915
Cell death & disease 2019 Dec 4;10(12):915
CLDN6 promotes tumor progression through the YAP1-snail1 axis in gastric cancer.
Yu S, Zhang Y, Li Q, Zhang Z, Zhao G, Xu J
Cell death & disease 2019 Dec 11;10(12):949
Cell death & disease 2019 Dec 11;10(12):949
Myricetin Suppresses the Propagation of Hepatocellular Carcinoma via Down-Regulating Expression of YAP.
Li M, Chen J, Yu X, Xu S, Li D, Zheng Q, Yin Y
Cells 2019 Apr 17;8(4)
Cells 2019 Apr 17;8(4)
LncRNA PCGEM1 Induces Ovarian Carcinoma Tumorigenesis and Progression Through RhoA Pathway.
Chen S, Wang LL, Sun KX, Liu Y, Guan X, Zong ZH, Zhao Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(4):1578-1588
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(4):1578-1588
lncRNA PFAR Promotes Lung Fibroblast Activation and Fibrosis by Targeting miR-138 to Regulate the YAP1-Twist Axis.
Zhao X, Sun J, Chen Y, Su W, Shan H, Li Y, Wang Y, Zheng N, Shan H, Liang H
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Sep 5;26(9):2206-2217
Molecular therapy : the journal of the American Society of Gene Therapy 2018 Sep 5;26(9):2206-2217
Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress.
Zhang X, Li Y, Ma Y, Yang L, Wang T, Meng X, Zong Z, Sun X, Hua X, Li H
Journal of experimental & clinical cancer research : CR 2018 Sep 4;37(1):216
Journal of experimental & clinical cancer research : CR 2018 Sep 4;37(1):216
Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4.
Zanconato F, Battilana G, Forcato M, Filippi L, Azzolin L, Manfrin A, Quaranta E, Di Biagio D, Sigismondo G, Guzzardo V, Lejeune P, Haendler B, Krijgsveld J, Fassan M, Bicciato S, Cordenonsi M, Piccolo S
Nature medicine 2018 Oct;24(10):1599-1610
Nature medicine 2018 Oct;24(10):1599-1610
Tumour YAP1 and PTEN expression correlates with tumour-associated myeloid suppressor cell expansion and reduced survival in colorectal cancer.
Yang R, Cai TT, Wu XJ, Liu YN, He J, Zhang XS, Ma G, Li J
Immunology 2018 Oct;155(2):263-272
Immunology 2018 Oct;155(2):263-272
The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ.
Chang L, Azzolin L, Di Biagio D, Zanconato F, Battilana G, Lucon Xiccato R, Aragona M, Giulitti S, Panciera T, Gandin A, Sigismondo G, Krijgsveld J, Fassan M, Brusatin G, Cordenonsi M, Piccolo S
Nature 2018 Nov;563(7730):265-269
Nature 2018 Nov;563(7730):265-269
Angiomotins stimulate LATS kinase autophosphorylation and act as scaffolds that promote Hippo signaling.
Mana-Capelli S, McCollum D
The Journal of biological chemistry 2018 Nov 23;293(47):18230-18241
The Journal of biological chemistry 2018 Nov 23;293(47):18230-18241
The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition.
Shi J, Li F, Yao X, Mou T, Xu Z, Han Z, Chen S, Li W, Yu J, Qi X, Liu H, Li G
Oncogene 2018 May;37(22):3022-3038
Oncogene 2018 May;37(22):3022-3038
REGγ deficiency suppresses tumor progression via stabilizing CK1ε in renal cell carcinoma.
Chen S, Wang Q, Wang L, Chen H, Gao X, Gong D, Ma J, Kubra S, Yao X, Li X, Li L, Zhai W, Zheng J
Cell death & disease 2018 May 24;9(6):627
Cell death & disease 2018 May 24;9(6):627
YAP1 contributes to NSCLC invasion and migration by promoting Slug transcription via the transcription co-factor TEAD.
Yu M, Chen Y, Li X, Yang R, Zhang L, Huangfu L, Zheng N, Zhao X, Lv L, Hong Y, Liang H, Shan H
Cell death & disease 2018 May 1;9(5):464
Cell death & disease 2018 May 1;9(5):464
An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness.
Galarza Torre A, Shaw JE, Wood A, Gilbert HTJ, Dobre O, Genever P, Brennan K, Richardson SM, Swift J
Scientific reports 2018 Jun 12;8(1):8981
Scientific reports 2018 Jun 12;8(1):8981
ZEB1 stimulates breast cancer growth by up-regulating hTERT expression.
Yu P, Shen X, Yang W, Zhang Y, Liu C, Huang T
Biochemical and biophysical research communications 2018 Jan 22;495(4):2505-2511
Biochemical and biophysical research communications 2018 Jan 22;495(4):2505-2511
MicroRNA-200a confers chemoresistance by antagonizing TP53INP1 and YAP1 in human breast cancer.
Yu SJ, Yang L, Hong Q, Kuang XY, Di GH, Shao ZM
BMC cancer 2018 Jan 12;18(1):74
BMC cancer 2018 Jan 12;18(1):74
Spatial patterning of liver progenitor cell differentiation mediated by cellular contractility and Notch signaling.
Kaylan KB, Berg IC, Biehl MJ, Brougham-Cook A, Jain I, Jamil SM, Sargeant LH, Cornell NJ, Raetzman LT, Underhill GH
eLife 2018 Dec 27;7
eLife 2018 Dec 27;7
Melatonin Protects against Lung Fibrosis by Regulating the Hippo/YAP Pathway.
Zhao X, Sun J, Su W, Shan H, Zhang B, Wang Y, Shabanova A, Shan H, Liang H
International journal of molecular sciences 2018 Apr 9;19(4)
International journal of molecular sciences 2018 Apr 9;19(4)
MiR-361 targets Yes-associated protein (YAP) mRNA to suppress cell proliferation in lung cancer.
Zhang S, Liu Z, Wu L, Wang Y
Biochemical and biophysical research communications 2017 Oct 21;492(3):468-473
Biochemical and biophysical research communications 2017 Oct 21;492(3):468-473
Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling.
Serafimidis I, Rodriguez-Aznar E, Lesche M, Yoshioka K, Takuwa Y, Dahl A, Pan D, Gavalas A
PLoS biology 2017 Mar;15(3):e2000949
PLoS biology 2017 Mar;15(3):e2000949
MiR-375 and Doxorubicin Co-delivered by Liposomes for Combination Therapy of Hepatocellular Carcinoma.
Fan YP, Liao JZ, Lu YQ, Tian DA, Ye F, Zhao PX, Xiang GY, Tang WX, He XX
Molecular therapy. Nucleic acids 2017 Jun 16;7:181-189
Molecular therapy. Nucleic acids 2017 Jun 16;7:181-189
The oncoprotein HBXIP up-regulates YAP through activation of transcription factor c-Myb to promote growth of liver cancer.
Wang Y, Fang R, Cui M, Zhang W, Bai X, Wang H, Liu B, Zhang X, Ye L
Cancer letters 2017 Jan 28;385:234-242
Cancer letters 2017 Jan 28;385:234-242
Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells.
Wei X, Ye J, Shang Y, Chen H, Liu S, Liu L, Wang R
Oncotarget 2017 Dec 12;8(65):109301-109318
Oncotarget 2017 Dec 12;8(65):109301-109318
E-Cadherin-Mediated Cell Contact Controls the Epidermal Damage Response in Radiation Dermatitis.
Xie G, Ao X, Lin T, Zhou G, Wang M, Wang H, Chen Y, Li X, Xu B, He W, Han H, Ramot Y, Paus R, Yue Z
The Journal of investigative dermatology 2017 Aug;137(8):1731-1739
The Journal of investigative dermatology 2017 Aug;137(8):1731-1739
ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types.
Lehmann W, Mossmann D, Kleemann J, Mock K, Meisinger C, Brummer T, Herr R, Brabletz S, Stemmler MP, Brabletz T
Nature communications 2016 Feb 15;7:10498
Nature communications 2016 Feb 15;7:10498
Paper-based microreactor array for rapid screening of cell signaling cascades.
Huang CH, Lei KF, Tsang NM
Lab on a chip 2016 Aug 7;16(15):2911-20
Lab on a chip 2016 Aug 7;16(15):2911-20
Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth.
Li L, Fang R, Liu B, Shi H, Wang Y, Zhang W, Zhang X, Ye L
Oncogene 2016 Aug 4;35(31):4048-57
Oncogene 2016 Aug 4;35(31):4048-57
Lats1 Deletion Causes Increased Germ Cell Apoptosis and Follicular Cysts in Mouse Ovaries.
Sun T, Pepling ME, Diaz FJ
Biology of reproduction 2015 Jul;93(1):22
Biology of reproduction 2015 Jul;93(1):22
A hairpin within YAP mRNA 3'UTR functions in regulation at post-transcription level.
Gao Y, Wang Y, Feng J, Feng G, Zheng M, Yang Z, Xiao Z, Lu Z, Ye L, Zhang X
Biochemical and biophysical research communications 2015 Apr 3;459(2):306-312
Biochemical and biophysical research communications 2015 Apr 3;459(2):306-312
Nicotine activates YAP1 through nAChRs mediated signaling in esophageal squamous cell cancer (ESCC).
Zhao Y, Zhou W, Xue L, Zhang W, Zhan Q
PloS one 2014;9(3):e90836
PloS one 2014;9(3):e90836
MiR-506 suppresses proliferation of hepatoma cells through targeting YAP mRNA 3'UTR.
Wang Y, Cui M, Sun BD, Liu FB, Zhang XD, Ye LH
Acta pharmacologica Sinica 2014 Sep;35(9):1207-14
Acta pharmacologica Sinica 2014 Sep;35(9):1207-14
Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility.
Wang Z, Wu Y, Wang H, Zhang Y, Mei L, Fang X, Zhang X, Zhang F, Chen H, Liu Y, Jiang Y, Sun S, Zheng Y, Li N, Huang L
Proceedings of the National Academy of Sciences of the United States of America 2014 Jan 7;111(1):E89-98
Proceedings of the National Academy of Sciences of the United States of America 2014 Jan 7;111(1):E89-98
Yes-associated protein (yap) is required for early embryonic development in zebrafish (danio rerio).
Hu J, Sun S, Jiang Q, Sun S, Wang W, Gui Y, Song H
International journal of biological sciences 2013;9(3):267-78
International journal of biological sciences 2013;9(3):267-78
MicroRNA-200a promotes anoikis resistance and metastasis by targeting YAP1 in human breast cancer.
Yu SJ, Hu JY, Kuang XY, Luo JM, Hou YF, Di GH, Wu J, Shen ZZ, Song HY, Shao ZM
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Mar 15;19(6):1389-99
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Mar 15;19(6):1389-99
Hepatitis B virus X protein modulates oncogene Yes-associated protein by CREB to promote growth of hepatoma cells.
Zhang T, Zhang J, You X, Liu Q, Du Y, Gao Y, Shan C, Kong G, Wang Y, Yang X, Ye L, Zhang X
Hepatology (Baltimore, Md.) 2012 Dec;56(6):2051-9
Hepatology (Baltimore, Md.) 2012 Dec;56(6):2051-9
Hippo signaling regulates pancreas development through inactivation of Yap.
George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE
Molecular and cellular biology 2012 Dec;32(24):5116-28
Molecular and cellular biology 2012 Dec;32(24):5116-28
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 13584-1-AP(YAP1 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells using 13584-1-AP( YAP1 Antibody) at dilution of 1:50 and Rhodamine-Goat anti-Rabbit IgG
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human ovary tumor using 13584-1-AP(YAP1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue