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antibody from antibodies-online
Targeting: YAP1
YAP65
Western blot
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Immunoprecipitation Immunohistochemistry Chromatin ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [16]
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- Validations
- Western blot [3]
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- Product number
- ABIN258559 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Yes-Associated Protein 1 (YAP1) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.
Deubiquitinase YOD1 potentiates YAP/TAZ activities through enhancing ITCH stability.
YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis.
PRKCI promotes immune suppression in ovarian cancer.
Dystrophin-glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation.
Homeostatic Control of Hpo/MST Kinase Activity through Autophosphorylation-Dependent Recruitment of the STRIPAK PP2A Phosphatase Complex.
Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury.
A Hippo and Fibroblast Growth Factor Receptor Autocrine Pathway in Cholangiocarcinoma.
Matrix-Stiffness-Regulated Inverse Expression of Krüppel-Like Factor 5 and Krüppel-Like Factor 4 in the Pathogenesis of Renal Fibrosis.
RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells.
Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells.
Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP.
β-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis.
Yes-associated protein (YAP) modulates oncogenic features and radiation sensitivity in endometrial cancer.
Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer.
Knockdown of GPC3 inhibits the proliferation of Huh7 hepatocellular carcinoma cells through down-regulation of YAP.
Plubell DL, Wilmarth PA, Zhao Y, Fenton AM, Minnier J, Reddy AP, Klimek J, Yang X, David LL, Pamir N
Molecular & cellular proteomics : MCP 2017 May;16(5):873-890
Molecular & cellular proteomics : MCP 2017 May;16(5):873-890
Deubiquitinase YOD1 potentiates YAP/TAZ activities through enhancing ITCH stability.
Kim Y, Kim W, Song Y, Kim JR, Cho K, Moon H, Ro SW, Seo E, Ryu YM, Myung SJ, Jho EH
Proceedings of the National Academy of Sciences of the United States of America 2017 May 2;114(18):4691-4696
Proceedings of the National Academy of Sciences of the United States of America 2017 May 2;114(18):4691-4696
YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis.
Lin C, Yao E, Zhang K, Jiang X, Croll S, Thompson-Peer K, Chuang PT
eLife 2017 Mar 21;6
eLife 2017 Mar 21;6
PRKCI promotes immune suppression in ovarian cancer.
Sarkar S, Bristow CA, Dey P, Rai K, Perets R, Ramirez-Cardenas A, Malasi S, Huang-Hobbs E, Haemmerle M, Wu SY, McGuire M, Protopopov A, Jiang S, Liu JF, Hirsch MS, Chang Q, Lazar AJ, Sood AK, Drapkin R, DePinho R, Draetta G, Chin L
Genes & development 2017 Jun 1;31(11):1109-1121
Genes & development 2017 Jun 1;31(11):1109-1121
Dystrophin-glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation.
Morikawa Y, Heallen T, Leach J, Xiao Y, Martin JF
Nature 2017 Jul 13;547(7662):227-231
Nature 2017 Jul 13;547(7662):227-231
Homeostatic Control of Hpo/MST Kinase Activity through Autophosphorylation-Dependent Recruitment of the STRIPAK PP2A Phosphatase Complex.
Zheng Y, Liu B, Wang L, Lei H, Pulgar Prieto KD, Pan D
Cell reports 2017 Dec 19;21(12):3612-3623
Cell reports 2017 Dec 19;21(12):3612-3623
Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury.
Tao G, Kahr PC, Morikawa Y, Zhang M, Rahmani M, Heallen TR, Li L, Sun Z, Olson EN, Amendt BA, Martin JF
Nature 2016 Jun 2;534(7605):119-23
Nature 2016 Jun 2;534(7605):119-23
A Hippo and Fibroblast Growth Factor Receptor Autocrine Pathway in Cholangiocarcinoma.
Rizvi S, Yamada D, Hirsova P, Bronk SF, Werneburg NW, Krishnan A, Salim W, Zhang L, Trushina E, Truty MJ, Gores GJ
The Journal of biological chemistry 2016 Apr 8;291(15):8031-47
The Journal of biological chemistry 2016 Apr 8;291(15):8031-47
Matrix-Stiffness-Regulated Inverse Expression of Krüppel-Like Factor 5 and Krüppel-Like Factor 4 in the Pathogenesis of Renal Fibrosis.
Chen WC, Lin HH, Tang MJ
The American journal of pathology 2015 Sep;185(9):2468-81
The American journal of pathology 2015 Sep;185(9):2468-81
RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells.
Brusgard JL, Choe M, Chumsri S, Renoud K, MacKerell AD Jr, Sudol M, Passaniti A
Oncotarget 2015 Sep 29;6(29):28132-50
Oncotarget 2015 Sep 29;6(29):28132-50
Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells.
Karystinou A, Roelofs AJ, Neve A, Cantatore FP, Wackerhage H, De Bari C
Arthritis research & therapy 2015 May 30;17:147
Arthritis research & therapy 2015 May 30;17:147
Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP.
Chen Q, Zhang N, Xie R, Wang W, Cai J, Choi KS, David KK, Huang B, Yabuta N, Nojima H, Anders RA, Pan D
Genes & development 2015 Jun 15;29(12):1285-97
Genes & development 2015 Jun 15;29(12):1285-97
β-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis.
Cai J, Maitra A, Anders RA, Taketo MM, Pan D
Genes & development 2015 Jul 15;29(14):1493-506
Genes & development 2015 Jul 15;29(14):1493-506
Yes-associated protein (YAP) modulates oncogenic features and radiation sensitivity in endometrial cancer.
Tsujiura M, Mazack V, Sudol M, Kaspar HG, Nash J, Carey DJ, Gogoi R
PloS one 2014;9(6):e100974
PloS one 2014;9(6):e100974
Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer.
Kapoor A, Yao W, Ying H, Hua S, Liewen A, Wang Q, Zhong Y, Wu CJ, Sadanandam A, Hu B, Chang Q, Chu GC, Al-Khalil R, Jiang S, Xia H, Fletcher-Sananikone E, Lim C, Horwitz GI, Viale A, Pettazzoni P, Sanchez N, Wang H, Protopopov A, Zhang J, Heffernan T, Johnson RL, Chin L, Wang YA, Draetta G, DePinho RA
Cell 2014 Jul 3;158(1):185-197
Cell 2014 Jul 3;158(1):185-197
Knockdown of GPC3 inhibits the proliferation of Huh7 hepatocellular carcinoma cells through down-regulation of YAP.
Miao HL, Pan ZJ, Lei CJ, Wen JY, Li MY, Liu ZK, Qiu ZD, Lin MZ, Chen NP, Chen M
Journal of cellular biochemistry 2013 Mar;114(3):625-31
Journal of cellular biochemistry 2013 Mar;114(3):625-31
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
