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Blocking/NeutralizingAntibody data
- Antibody Data
- Antigen structure
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- Product number
- MAB8234-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse IFN-beta Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from cell culture supernatant. Detects mouse IFN-beta in direct ELISAs.
- Reactivity
- Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Antigen sequence
P01575- Isotype
- IgG
- Antibody clone number
- 1176D
- Vial size
- 100 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- IFN-beta Inhibition of Viral-induced Cytopathy and Neutralization by Mouse IFN-beta Antibody. Recombinant Mouse IFN-beta (Catalog # 8234-MB) reduces the viral-induced cytopathy in the L-929 mouse fibroblast cell line in a dose-dependent manner (orange line) as measured by Resazurin (Catalog # AR002). Inhibition of viral activity elicited by Recombinant Mouse IFN-beta (10 pg/mL) is neutralized (green line) by increasing concentrations of Rabbit Anti-Mouse IFN-beta Monoclonal Antibody (Catalog # MAB8234). The ND50 is typically 0.25-1.25 µg/mL.
