16-9978-81

antibody from Invitrogen Antibodies
Targeting: IFNB1 IFB, IFF, IFNB
Provider product page for 16-9978-81
Blocking/Neutralizing
Other assay

Antibody data

Product number
16-9978-81 - Provider product page
Provider
Invitrogen Antibodies
Product name
IFN beta Monoclonal Antibody (A1 (IFNb)), Functional Grade, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The A1 monoclonal antibody reacts with human IFN-beta. The A1 antibody is a neutralizing antibody. IFN-beta is classified as a type I IFN which is a group of structurally and functionally related proteins demonstrating anti-viral, anti-parasitic, and anti-proliferative activities. Applications Reported: The A1 antibody has been reported for use in cytokine neutralization. Applications Tested: The Functional Grade Purified A1 antibody has been tested in bioassay for neutralization of IFN-beta bioactivity. The A1 antibody at 3-6 µg/mL has been found to inhibit by 50% the biological effects of 50 pg/mL human IFN-beta (ND50), in an EMCV assay of A549 cell protection. Detailed information and protocols about cytokine bioassays and in vitro cytokine neutralization using antibodies can be found in the Best Protocols® section. Storage and handling: Use in a sterile environment. Filtration: 0.2 µm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
A1 (IFNb)
Vial size
50 µg
Concentration
1 mg/mL
Storage
4° C
IFNB1 protein structure - 16-9978-81 shown in red.