27506-1-AP

antibody from Proteintech Group

Targeting: IFNB1 IFB, IFF, IFNB

Provider product page for 27506-1-AP

ELISA

Immunocytochemistry

Antibody data

Antibody Data
Antigen structure
References [33]
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Product number: 27506-1-AP - Provider product page
Provider: Proteintech Group
Product name: IFN Beta antibody
Antibody type: Polyclonal
Description: IFN Beta antibody (Cat. #27506-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human and has been validated for the following applications: IF,ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

IFNB1 protein structure - 27506-1-AP shown in red.

Submitted references A biomimetic arsenic-based nanozyme enhances dual epigenetic regulation to improve the efficacy of immunotherapy for acute myeloid leukaemia.

Chang A, Peng H, Chen Y, Zhang H, Xu X, Zhang K, Yang J, Li W, Wang X, Dong X, Ni J
Biomaterials 2026 Oct;333:124215

Hyaluronic acid-coated Cu/Mn Prussian blue nanocubes amplify cuproptosis and cGAS-STING signaling for synergistic prostate cancer therapy.

Yao X, Ruan Y, Rao T, Lin F, Zhang W
International journal of biological macromolecules 2026 May;362:152036

IFITM1 is required for epithelial mesenchymal transition in airway remodeling of allergic asthma.

Zhu M, Weng X, Zhang C, Song X, Liu S, Xu T, Wang Z, Chen Z, Zhang M, Huang M, Ji N
The World Allergy Organization journal 2026 Mar;19(3):101339

Type I interferon-induced CD169(+) macrophages play a protective role in periodontitis.

Lu J, Xiong Z, Wu X, Yang Y, Zhang J, Luo L
Journal of periodontology 2026 Mar 6;

GFER Represents a Target for Dual Disruption of Redox Homeostasis and Reactivation of the Immune Response in Pancreatic Adenocarcinoma.

Chen Z, Ho IL, Liu J, Soeung M, Yen EY, Sainani S, Dyke CA, Shah R, Kwon HJ, Han G, Yan X, Zhang S, Srinivasan S, Rose JL, Citron F, Jiang S, Chang Q, Feng N, Genovese G, Gao S, Yao W, Wang L, Wang H, Ying H, Viale A, Draetta GF
Cancer research 2026 Mar 2;86(5):1132-1147

Gamma-aminobutyric acid transaminase mediates tumor suppression in renal cell carcinoma through the cGAS-STING-interferon-β axis.

Feng Y, Cao S, Cai T, Lu Y, Jiang B, Lv Z, Tang J, Gao F, Zhao X, Liu C, Wang Q, Feng J, Wang Z, Ai Q, Cheng Q, Fan W, Li H
Scientific reports 2026 Mar 11;16(1)

Functional and metabolic dysbiosis of the gut microbiome in the tumoral immune microenvironment of hepatocellular carcinoma.

He Q, Wu H, Guo M, Ye R, Li H, Zhang Q
Cellular signalling 2026 Jul;143:112455

Airway immune profiles and therapeutic implications of IGF1 in eosinophilic granulomatosis with polyangiitis.

Dong C, Lu B, Zhong C, Ou C, Yang X, Wang L, Zuo X, Xue L, Lu C, Wang S, Wen J, Ma J, Deng Z, Liu Y, Ma L, Liu M, Lew AM, Mukherjee M, Nair P, Zhong N, Chen R, Chen Z, Zhang Y, Zhang Q
Nature communications 2026 Jan 7;17(1):1346

Cucurbitacin B Inhibits Hepatocellular Carcinoma by Inducing Ferroptosis and Activating the cGAS-STING Pathway.

Zhang H, Chang A, Xu X, Peng H, Zhang K, Yang J, Li W, Wang X, Wang W, Yin X, Qu C, Dong X, Ni J
Current issues in molecular biology 2026 Jan 27;48(2)

Type I Interferons Induce CD8(+) T Cell Chemotaxis Through Regulating Melanocyte but Not Keratinocyte CXCL9/10/11 Secretion in the Initiation of Vitiligo.

Wang D, Yang L, Zhang Y, Zhang H, Yang L, Chen L, Katayama I, Li Y, Chen K, Wu H
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71575

Inhibition of CDH11 Activates cGAS-STING by Stimulating Branched Chain Amino Acid Catabolism and Mitigates Lung Metastasis of Adenoid Cystic Carcinoma.

Li RF, Liu S, Gao Q, Fu M, Sun XY, Xiao M, Ge XY, Peng X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2408751

Hepatitis B virus confers innate immunity evasion through hepatitis B virus-miR-3 down-regulation of cGAS-Sting-IFN signaling.

Xu ZY, Gao JS, He Y, Xiao XQ, Gong GZ, Zhang M
World journal of hepatology 2025 Feb 27;17(2):99292

TAK-981 potentiates doxorubicin immunocide in triple-negative breast cancer by IFN I-dependent NK cell stimulation.

Liu J, Wang Y, Wei X, Liu S, Hu C, Peng P, Wu W, Cai J, Sun H
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):1871-1887

Mild microwave hyperthermia promotes mitotic catastrophe, induces time-delayed cGAS-STING activation and restores sensitivity to anti-PDL1 therapy in Pan02 pancreatic cancer model.

Li N, He J, Chen M, Liang S, Zhang C, Pan W, Wang Q, Piao F, Wang R, Yu J, Gong G
Oncoimmunology 2025 Dec 31;14(1):2602216

IL1RA inhibits the progression of oral squamous cell carcinoma by mediating type Ⅰ interferon response.

Ding Y, Shan Y, Gu J, Yi J, Sun Z
Translational oncology 2025 Aug;58:102428

Oxidative stress-induced release of mitochondrial DNA (mtDNA) promotes the progression of vitiligo by activating the cGAS-STING signaling pathway in monocytes.

Wu T, Chen X, Fan J, Ye P, Zhang J, Wang Z, Zhou Y, Wang B, Jin X, Xiong S, Gao S, Chang Y, Li C, Jian Z
Free radical biology & medicine 2025 Aug 1;235:43-55

8-Oxoguanine modifications in peripheral leukocyte microRNAs promote age-related inflammation by remodeling gene regulatory networks.

Han MM, Liu Q, Yang L, Li J, Wang QY, Zhang YM, Guo JQ, Zeng LT, Qi RM, Cai JP
Free radical biology & medicine 2025 Aug 1;235:261-279

Cancer Cell-Intrinsic Type I Interferon Signaling Promotes Antitumor Immunity in Head and Neck Squamous Cell Carcinoma.

Xie G, Yang C, Pang X, Wu TC, Gu X
Cancers 2025 Apr 10;17(8)

Extracellular vesicles from neural stem cells safeguard neurons in intracerebral hemorrhage by suppressing reactive astrocyte neurotoxicity.

Li T, Zhang L, Wang P, Yu J, Zhong J, Tang Q, Zhu T, Chen K, Li F, Hong P, Wei J, Sun X, Ji G, Song B, Zhu J
Cell reports 2024 Oct 22;43(10):114854

IFN-β contributes to astrocyte activation in the brain following coronavirus PHEV infection independent on peripheral immunity.

Shi J, Jia Q, Yu Y, Zhang J, Li Z, He W
Veterinary microbiology 2024 Nov;298:110280

The role of HPV11 E7 in modulating STING-dependent interferon β response in recurrent respiratory papillomatosis.

Chen L, Hu H, Pan Y, Lu Y, Zhao M, Zhao Y, Wang L, Liu K, Yu Z
Journal of virology 2024 May 14;98(5):e0192523

A1CF Binding to the p65 Interaction Site on NKRF Decreased IFN-β Expression and p65 Phosphorylation (Ser536) in Renal Carcinoma Cells.

Liu Y, Yang J, Weng D, Xie Y
International journal of molecular sciences 2024 Mar 22;25(7)

hnRNPM protects against the dsRNA-mediated interferon response by repressing LINE-associated cryptic splicing.

Zheng R, Dunlap M, Bobkov GOM, Gonzalez-Figueroa C, Patel KJ, Lyu J, Harvey SE, Chan TW, Quinones-Valdez G, Choudhury M, Le Roux CA, Bartels MD, Vuong A, Flynn RA, Chang HY, Van Nostrand EL, Xiao X, Cheng C
Molecular cell 2024 Jun 6;84(11):2087-2103.e8

A novel immunogenic cell death-related subtype classification and risk signature for predicting prognosis and immunotherapy efficacy in gastric cancer.

Dong B, Wu Y, Zhang J, Gu Y, Xie R, He X, Pang X, Wang X, Cui Y
Frontiers in immunology 2023;14:1162876

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Xie G, Shan L, Yang C, Liu Y, Pang X, Teng S, Wu TC, Gu X
Scientific reports 2023 Oct 28;13(1):18476

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Liu W, Mu G, Jia Y, Yu M, Zhang S, Wang Z, Fang S
BMC veterinary research 2023 Dec 13;19(1):270

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Cancer science 2023 Aug;114(8):3162-3175

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Li JJ, Liu ML, Lv JN, Chen RL, Ding K, He JQ
International immunopharmacology 2022 Mar;104:108510

Magnetic hyperthermia induces effective and genuine immunogenic tumor cell death with respect to exogenous heating.

Yan B, Liu C, Wang S, Li H, Jiao J, Lee WSV, Zhang S, Hou Y, Hou Y, Ma X, Fan H, Lv Y, Liu X
Journal of materials chemistry. B 2022 Jul 20;10(28):5364-5374

Escherichia coli infection activates the production of IFN-α and IFN-β via the JAK1/STAT1/2 signaling pathway in lung cells.

Jin Y, Jia Z, Cai Q, Sun Y, Liu Z
Amino acids 2021 Oct;53(10):1609-1622

Intracellular virus sensor MDA5 exacerbates vitiligo by inducing the secretion of chemokines in keratinocytes under virus invasion.

Zhuang T, Yi X, Chen J, Kang P, Chen X, Chen J, Cui T, Chang Y, Ye Z, Ni Q, Wang Y, Du P, Li B, Liu L, Jian Z, Li K, Gao T, Li S, Li C
Cell death & disease 2020 Jun 12;11(6):453

Role of heparan sulfate in the Zika virus entry, replication, and cell death.

Gao H, Lin Y, He J, Zhou S, Liang M, Huang C, Li X, Liu C, Zhang P
Virology 2019 Mar;529:91-100

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