Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS7267 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- THP polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human THP.
- Description
- Tamm-Horsfall glycoprotein (also referred to as uromodulin or THP) is the most abundant protein found in normal urine. THP is expressed on the luminal surface of the membrane with the glycosyl phosphatidylinositol (GPI) anchor and excreted in urine at a rate of 50-100 mg per day. THP, uropontin and nephrocalcin are the three known urinary glycoproteins that affect the formation of calcium-containing kidney stones. THP is synthesized by kidney epithelial cells and is believed to play important and diverse roles in the urinary system,including renal water balance, immunosuppression, urinary stone formation and inhibition of bacterial adhesion. THP is nontoxic and blocks early events required for normal T cell proliferation in vitro.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of THP polyclonal antibody