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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- sc-20687 - Provider product page
- Provider
- Santa Cruz Biotechnology
- Proper citation
- Santa Cruz Biotechnology Cat#sc-20687, RRID:AB_2111764
- Product name
- Anti-GLI1
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Reactivity
- Human
- Host
- Rabbit
Submitted references Dexamethasone destabilizes Nmyc to inhibit the growth of hedgehog-associated medulloblastoma.
Cross talk between hedgehog and epithelial-mesenchymal transition pathways in gastric pit cells and in diffuse-type gastric cancers.
Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma.
Expression of the glioma-associated oncogene homolog (GLI) 1 in human breast cancer is associated with unfavourable overall survival.
The hedgehog pathway transcription factor GLI1 promotes malignant behavior of cancer cells by up-regulating osteopontin.
Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells.
Differential expression of Sonic hedgehog and Gli1 in hematological malignancies
Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer.
Heine VM, Priller M, Ling J, Rowitch DH, Schüller U
Cancer research 2010 Jul 1;70(13):5220-5
Cancer research 2010 Jul 1;70(13):5220-5
Cross talk between hedgehog and epithelial-mesenchymal transition pathways in gastric pit cells and in diffuse-type gastric cancers.
Ohta H, Aoyagi K, Fukaya M, Danjoh I, Ohta A, Isohata N, Saeki N, Taniguchi H, Sakamoto H, Shimoda T, Tani T, Yoshida T, Sasaki H
British journal of cancer 2009 Jan 27;100(2):389-98
British journal of cancer 2009 Jan 27;100(2):389-98
Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma.
Taniguchi E, Cho MJ, Arenkiel BR, Hansen MS, Rivera OJ, McCleish AT, Qualman SJ, Guttridge DC, Scott MP, Capecchi MR, Keller C
Pediatric blood & cancer 2009 Aug;53(2):136-44
Pediatric blood & cancer 2009 Aug;53(2):136-44
Expression of the glioma-associated oncogene homolog (GLI) 1 in human breast cancer is associated with unfavourable overall survival.
ten Haaf A, Bektas N, von Serenyi S, Losen I, Arweiler EC, Hartmann A, Knüchel R, Dahl E
BMC cancer 2009 Aug 25;9:298
BMC cancer 2009 Aug 25;9:298
The hedgehog pathway transcription factor GLI1 promotes malignant behavior of cancer cells by up-regulating osteopontin.
Das S, Harris LG, Metge BJ, Liu S, Riker AI, Samant RS, Shevde LA
The Journal of biological chemistry 2009 Aug 21;284(34):22888-97
The Journal of biological chemistry 2009 Aug 21;284(34):22888-97
Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells.
Ferretti E, De Smaele E, Miele E, Laneve P, Po A, Pelloni M, Paganelli A, Di Marcotullio L, Caffarelli E, Screpanti I, Bozzoni I, Gulino A
The EMBO journal 2008 Oct 8;27(19):2616-27
The EMBO journal 2008 Oct 8;27(19):2616-27
Differential expression of Sonic hedgehog and Gli1 in hematological malignancies
L-Y Bai, C-F Chiu, C-W Lin, N-Y Hsu, C-L Lin, W-J Lo, M-C Kao
Leukemia 2007 Oct;22(1):226-228
Leukemia 2007 Oct;22(1):226-228
Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer.
Mukherjee S, Frolova N, Sadlonova A, Novak Z, Steg A, Page GP, Welch DR, Lobo-Ruppert SM, Ruppert JM, Johnson MR, Frost AR
Cancer biology & therapy 2006 Jun;5(6):674-83
Cancer biology & therapy 2006 Jun;5(6):674-83
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Supportive validation
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- Main image
- Experimental details
- Immunohistochemical staining of human cerebellum shows distinct nuclear and cytoplasmic positivity in purkinje cells.
- Validation comment
- Staining pattern partly consistent with experimental and/or bioinformatic data.
