66905-1-Ig

antibody from Proteintech Group

Targeting: GLI1 GLI

Provider product page for 66905-1-Ig

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Product number: 66905-1-Ig - Provider product page
Provider: Proteintech Group
Product name: GLI1 antibody
Antibody type: Monoclonal
Description: KD/KO validated GLI1 antibody (Cat. #66905-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, rat, mouse and has been validated for the following applications: WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 1D2B2
Vial size: 20ul, 150ul

GLI1 protein structure - 66905-1-Ig shown in red.

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GPC2 deficiency inhibits cell growth and metastasis in colon adenocarcinoma.

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Journal of molecular and cellular cardiology 2022 Oct;171:16-29

Hedgehog Signalling Contributes to Trauma-Induced Tendon Heterotopic Ossification and Regulates Osteogenesis through Antioxidant Pathway in Tendon-Derived Stem Cells.

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Antioxidants (Basel, Switzerland) 2022 Nov 16;11(11)

Kub3 Deficiency Causes Aberrant Late Embryonic Lung Development in Mice by the FGF Signaling Pathway.

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International journal of molecular sciences 2022 May 27;23(11)

Metformin regulates macrophage polarization via the Shh signaling pathway to improve pulmonary vascular development in bronchopulmonary dysplasia.

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IUBMB life 2022 Mar;74(3):259-271

Effect of kaempferol on hedgehog signaling pathway in rats with --chronic atrophic gastritis - Based on network pharmacological screening and experimental verification.

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Remodeling Chondroitin-6-Sulfate-Mediated Immune Exclusion Enhances Anti-PD-1 Response in Colorectal Cancer with Microsatellite Stability.

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Cancer immunology research 2022 Feb;10(2):182-199

Mutations in OSBPL2 cause hearing loss associated with primary cilia defects via sonic hedgehog signaling.

Shi H, Wang H, Zhang C, Lu Y, Yao J, Chen Z, Xing G, Wei Q, Cao X
JCI insight 2022 Feb 22;7(4)

Maternal sevoflurane exposure affects neural stem cell differentiation in offspring rats through NRF2 signaling.

Zhang Y, Kuai S, Zhang Y, Xue H, Wu Z, Zhao P
Neurotoxicology 2022 Dec;93:348-354

Sex-specific phenotypes in the aging mouse heart and consequences for chronic fibrosis.

Angelini A, Ortiz-Urbina J, Trial J, Reddy AK, Malovannaya A, Jain A, Entman ML, Taffet GE, Cieslik KA
American journal of physiology. Heart and circulatory physiology 2022 Aug 1;323(2):H285-H300

BRD4 promotes the migration and invasion of bladder cancer cells through the Sonic hedgehog signaling pathway and enhances cisplatin resistance.

Liu T, Zhang Z, Wang C, Huang H, Li Y
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Microtubule Stabilization Enhances the Chondrogenesis of Synovial Mesenchymal Stem Cells.

Li J, Sun Z, Lv Z, Jiang H, Liu A, Wang M, Tan G, Guo H, Sun H, Wu R, Xu X, Yan W, Jiang Q, Ikegawa S, Shi D
Frontiers in cell and developmental biology 2021;9:748804

Apatinib Suppresses Gastric Cancer Stem Cells Properties by Inhibiting the Sonic Hedgehog Pathway.

Cao W, Li Y, Sun H, Yang C, Zhu J, Xie C, Li X, Wu J, Geng S, Wang L, Sun L, Geng G, Han H, Zhong C
Frontiers in cell and developmental biology 2021;9:679806

Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway.

Sun H, Zhang T, Liu R, Cao W, Zhang Z, Liu Z, Qian W, Wang D, Yu D, Zhong C
Nutrition and cancer 2021;73(7):1157-1167

Mitochondrial Protection and Against Glutamate Neurotoxicity via Shh/Ptch1 Signaling Pathway to Ameliorate Cognitive Dysfunction by Kaixin San in Multi-Infarct Dementia Rats.

Li X, Wen W, Li P, Fu Y, Chen H, Wang F, Dai Y, Xu S
Oxidative medicine and cellular longevity 2021;2021:5590745

Hedgehog/GLI1 signaling pathway regulates the resistance to cisplatin in human osteosarcoma.

Chen D, Kang X, Li Z, Chen L, Ma Q, Fan P
Journal of Cancer 2021;12(22):6676-6684

Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.

Ding F, Yang S
Canadian journal of physiology and pharmacology 2021 Sep;99(9):910-920

Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.

Guo K, Wang P, Zhang L, Zhou Y, Dai X, Yan Y, Chen Y, Wasan HS, Yu J, Ruan S, Sun L
Cancer science 2021 Oct;112(10):4176-4186

Disruption of Gprasp2 down-regulates Hedgehog signaling and leads to apoptosis in auditory cells.

Lu Y, Zhang M, Wei Q, Chen Z, Xing G, Yao J, Cao X
Biochemical and biophysical research communications 2021 Oct 15;574:1-7

Circular RNA circIPO11 drives self-renewal of liver cancer initiating cells via Hedgehog signaling.

Gu Y, Wang Y, He L, Zhang J, Zhu X, Liu N, Wang J, Lu T, He L, Tian Y, Fan Z
Molecular cancer 2021 Oct 14;20(1):132

ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling.

Zhu T, Zheng J, Zhuo W, Pan P, Li M, Zhang W, Zhou H, Gao Y, Li X, Liu Z
Cell death discovery 2021 May 29;7(1):126

Identification of a potent antagonist of smoothened in hedgehog signaling.

Fan J, Li H, Kuang L, Zhao Z, He W, Liu C, Wang Y, Cheng SY, Chen W
Cell & bioscience 2021 Mar 2;11(1):46

Meningitic Escherichia coli α-hemolysin aggravates blood-brain barrier disruption via targeting TGFβ1-triggered hedgehog signaling.

Fu J, Li L, Huo D, Yang R, Yang B, Xu B, Yang X, Dai M, Tan C, Chen H, Wang X
Molecular brain 2021 Jul 19;14(1):116

Long noncoding RNA LINC00460 promotes the progression of cervical cancer via regulation of the miR-361-3p/Gli1 axis.

Li F, Zhu W, Wang Z
Human cell 2021 Jan;34(1):229-237

Astrocyte-Derived TGFβ1 Facilitates Blood-Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells.

Fu J, Li L, Huo D, Zhi S, Yang R, Yang B, Xu B, Zhang T, Dai M, Tan C, Chen H, Wang X
Brain sciences 2021 Jan 8;11(1)

Benzidine promotes the stemness of bladder cancer stem cells via activation of the Sonic hedgehog pathway.

Wang D, Xie D, Bi L, Wang Y, Zou C, Chen L, Geng H, Qian W, Li Y, Sun H, Wang X, Lu Y, Yu D, Zhong C
Oncology letters 2021 Feb;21(2):146

Decreased Indian hedgehog signaling activates autophagy in endometriosis and adenomyosis.

Zhou Y, Peng Y, Xia Q, Yan D, Zhang H, Zhang L, Chen Y, Zhao X, Li J
Reproduction (Cambridge, England) 2021 Feb;161(2):99-109

Pectin Oligosaccharides Enhance α2,6-Sialylation Modification that Promotes Apoptosis of Bladder Cancer Cells by Targeting the Hedgehog Pathway.

Huang Y, Wang T
Cell biochemistry and biophysics 2021 Dec;79(4):719-728

Repair of spinal cord injury in rats via exosomes from bone mesenchymal stem cells requires sonic hedgehog.

Jia Y, Yang J, Lu T, Pu X, Chen Q, Ji L, Luo C
Regenerative therapy 2021 Dec;18:309-315

Wogonin inhibits the growth of HT144 melanoma via regulating hedgehog signaling-mediated inflammation and glycolysis.

Li L, Ji Y, Zhang L, Cai H, Ji Z, Gu L, Yang S
International immunopharmacology 2021 Dec;101(Pt B):108222

TCF4 and HuR mediated-METTL14 suppresses dissemination of colorectal cancer via N6-methyladenosine-dependent silencing of ARRDC4.

Wang H, Wei W, Zhang ZY, Liu Y, Shi B, Zhong W, Zhang HS, Fang X, Sun CL, Wang JB, Liu LX
Cell death & disease 2021 Dec 17;13(1):3

Procyanidin B2 alleviates liver injury caused by cold stimulation through Sonic hedgehog signalling and autophagy.

Ma L, Li C, Lian S, Xu B, Lv H, Liu Y, Lu J, Ji H, Li S, Guo J, Yang H
Journal of cellular and molecular medicine 2021 Aug;25(16):8015-8027

Rab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer.

Peng C, Li X, Ye Z, Wu W
Scientific reports 2021 Aug 10;11(1):16243

Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.

Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348

microRNA-9-5p alleviates blood-brain barrier damage and neuroinflammation after traumatic brain injury.

Wu J, He J, Tian X, Luo Y, Zhong J, Zhang H, Li H, Cen B, Jiang T, Sun X
Journal of neurochemistry 2020 Jun;153(6):710-726

Liraglutide regulates proliferation, differentiation, and apoptosis of preosteoblasts through a signaling network of Notch/Wnt/Hedgehog signaling pathways.

Hou HW, Xue P, Wang Y, Li YK
European review for medical and pharmacological sciences 2020 Dec;24(23):12408-12422

A Combination of BRD4 and HDAC3 Inhibitors Synergistically Suppresses Glioma Stem Cell Growth by Blocking GLI1/IL6/STAT3 Signaling Axis.

Wang Q, Jia S, Wang D, Chen X, Kalvakolanu DV, Zheng H, Wei X, Wen N, Liang H, Guo B, Zhang L
Molecular cancer therapeutics 2020 Dec;19(12):2542-2553

Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells.

Li E, Zhang T, Sun X, Li Y, Geng H, Yu D, Zhong C
Oncology letters 2019 Sep;18(3):3081-3091

Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling.

Zhang Q, Cao WS, Wang XQ, Zhang M, Lu XM, Chen JQ, Chen Y, Ge MM, Zhong CY, Han HY
Phytotherapy research : PTR 2019 Oct;33(10):2783-2791

TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling.

Zhu R, Gires O, Zhu L, Liu J, Li J, Yang H, Ju G, Huang J, Ge W, Chen Y, Lu Z, Wang H
Nature communications 2019 Jun 28;10(1):2863

Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway.

Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, Meng Y, Chen Y, Wang X, Chen J, Zhang Q, Shao J, Zhong C
International journal of food sciences and nutrition 2019 Aug;70(5):570-578

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