Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- NBP1-78259 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-78259, RRID:AB_11030198
- Product name
- Rabbit Polyclonal GLI-1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1.08 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Pharmacological exposures may precipitate craniosynostosis through targeted stem cell depletion.
Genetic Mutations Underlying Phenotypic Plasticity in Basosquamous Carcinoma.
BMP-IHH-mediated interplay between mesenchymal stem cells and osteoclasts supports calvarial bone homeostasis and repair.
An Nfic-hedgehog signaling cascade regulates tooth root development.
The suture provides a niche for mesenchymal stem cells of craniofacial bones.
Secretion of shh by a neurovascular bundle niche supports mesenchymal stem cell homeostasis in the adult mouse incisor.
NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo.
Durham E, Howie RN, Larson N, LaRue A, Cray J
Stem cell research 2019 Oct;40:101528
Stem cell research 2019 Oct;40:101528
Genetic Mutations Underlying Phenotypic Plasticity in Basosquamous Carcinoma.
Chiang A, Tan CZ, Kuonen F, Hodgkinson LM, Chiang F, Cho RJ, South AP, Tang JY, Chang ALS, Rieger KE, Oro AE, Sarin KY
The Journal of investigative dermatology 2019 Nov;139(11):2263-2271.e5
The Journal of investigative dermatology 2019 Nov;139(11):2263-2271.e5
BMP-IHH-mediated interplay between mesenchymal stem cells and osteoclasts supports calvarial bone homeostasis and repair.
Guo Y, Yuan Y, Wu L, Ho TV, Jing J, Sugii H, Li J, Han X, Feng J, Guo C, Chai Y
Bone research 2018;6:30
Bone research 2018;6:30
An Nfic-hedgehog signaling cascade regulates tooth root development.
Liu Y, Feng J, Li J, Zhao H, Ho TV, Chai Y
Development (Cambridge, England) 2015 Oct 1;142(19):3374-82
Development (Cambridge, England) 2015 Oct 1;142(19):3374-82
The suture provides a niche for mesenchymal stem cells of craniofacial bones.
Zhao H, Feng J, Ho TV, Grimes W, Urata M, Chai Y
Nature cell biology 2015 Apr;17(4):386-96
Nature cell biology 2015 Apr;17(4):386-96
Secretion of shh by a neurovascular bundle niche supports mesenchymal stem cell homeostasis in the adult mouse incisor.
Zhao H, Feng J, Seidel K, Shi S, Klein O, Sharpe P, Chai Y
Cell stem cell 2014 Feb 6;14(2):160-73
Cell stem cell 2014 Feb 6;14(2):160-73
NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo.
Jalili A, Mertz KD, Romanov J, Wagner C, Kalthoff F, Stuetz A, Pathria G, Gschaider M, Stingl G, Wagner SN
PloS one 2013;8(7):e69064
PloS one 2013;8(7):e69064
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: GLI-1 Antibody [NBP1-78259] - Analysis of GLI-1 on partial recombinant GLI-1 protein (molecular weight of partial recombinant protein is 37 kDa).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: GLI-1 Antibody [NBP1-78259] - Analysis of GLI-1 in mouse brain using DAB with hematoxylin counterstain.