orb1467381

antibody from Biorbyt
Targeting: PPM1D PP2C-DELTA, Wip1
Provider product page for orb1467381
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
orb1467381 - Provider product page
Provider
Biorbyt
Product name
Anti-PPM1D Purified
Antibody type
Monoclonal
Description
PPM1D is a Mg2+/Mn2+ dependent protein phosphatase 1D with inducible expression in response to various types of environmental stress. This expression is p53-dependent, and subsequently PPM1D negatively regulates the p53-mediated transcription, thus it suppresses the apoptosis. PPM1D contributes to development of carcinomas, and seems to be a promissing therapeutic target. Amplification of PPM1D is associated with breast cancer.
Reactivity
Human, Mouse
Conjugate
Unconjugated
Antibody clone number
7E11/C5
Vial size
0.1 mg
Concentration
1 mg/ml
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PPM1D protein structure - orb1467381 shown in red.