orb1467381

antibody from Biorbyt

Targeting: PPM1D PP2C-DELTA, Wip1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

orb1467381

Provider

Biorbyt

Product name

PPM1D Antibody

Antibody type

Monoclonal

Description

PPM1D is a Mg2+/Mn2+ dependent protein phosphatase 1D with inducible expression in response to various types of environmental stress. This expression is p53-dependent, and subsequently PPM1D negatively regulates the p53-mediated transcription, thus it suppresses the apoptosis. PPM1D contributes to development of carcinomas, and seems to be a promissing therapeutic target. Amplification of PPM1D is associated with breast cancer.

Reactivity

Human, Mouse

Conjugate

Unconjugated

Antibody clone number

7E11/C5

Vial size

0.1 mg

Concentration

1 mg/ml

Storage

Store at 2-8°C. Do not freeze.