ABIN1449195

antibody from antibodies-online

Targeting: CYBA p22-PHOX

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN1449195

Provider

antibodies-online

Product name

anti-Cytochrome B-245, alpha Polypeptide (CYBA) antibody (PE)

Antibody type

Monoclonal

Description

Protein A agarose

Reactivity

Human, Simian

Host

Mouse

Conjugate

Yellow dye

Isotype

IgG

Antibody clone number

7D5

Vial size

50 tests

Storage

Store at 2-8°C.

References

Submitted references

Deletion mutagenesis of p22phox subunit of flavocytochrome b558: identification of regions critical for gp91phox maturation and NADPH oxidase activity.

Zhu Y, Marchal CC, Casbon AJ, Stull N, von Löhneysen K, Knaus UG, Jesaitis AJ, McCormick S, Nauseef WM, Dinauer MC
The Journal of biological chemistry 2006 Oct 13;281(41):30336-46

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Helicobacter pylori disrupts NADPH oxidase targeting in human neutrophils to induce extracellular superoxide release.

Allen LA, Beecher BR, Lynch JT, Rohner OV, Wittine LM
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 15;174(6):3658-67

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Crucial role of two potential cytosolic regions of Nox2, 191TSSTKTIRRS200 and 484DESQANHFAVHHDEEKD500, on NADPH oxidase activation.

Li XJ, Grunwald D, Mathieu J, Morel F, Stasia MJ
The Journal of biological chemistry 2005 Apr 15;280(15):14962-73

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Anaplasma phagocytophilum utilizes multiple host evasion mechanisms to thwart NADPH oxidase-mediated killing during neutrophil infection.

Carlyon JA, Abdel-Latif D, Pypaert M, Lacy P, Fikrig E
Infection and immunity 2004 Aug;72(8):4772-83

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Concentrated RD114-pseudotyped MFGS-gp91phox vector achieves high levels of functional correction of the chronic granulomatous disease oxidase defect in NOD/SCID/beta -microglobulin-/- repopulating mobilized human peripheral blood CD34+ cells.

Brenner S, Whiting-Theobald NL, Linton GF, Holmes KL, Anderson-Cohen M, Kelly PF, Vanin EF, Pilon AM, Bodine DM, Horwitz ME, Malech HL
Blood 2003 Oct 15;102(8):2789-97

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Functional epitope on human neutrophil flavocytochrome b558.

Burritt JB, Foubert TR, Baniulis D, Lord CI, Taylor RM, Mills JS, Baughan TD, Roos D, Parkos CA, Jesaitis AJ
Journal of immunology (Baltimore, Md. : 1950) 2003 Jun 15;170(12):6082-9

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Absence of proton channels in COS-7 cells expressing functional NADPH oxidase components.

Morgan D, Cherny VV, Price MO, Dinauer MC, DeCoursey TE
The Journal of general physiology 2002 Jun;119(6):571-80

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Repression of rac2 mRNA expression by Anaplasma phagocytophila is essential to the inhibition of superoxide production and bacterial proliferation.

Carlyon JA, Chan WT, Galán J, Roos D, Fikrig E
Journal of immunology (Baltimore, Md. : 1950) 2002 Dec 15;169(12):7009-18

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A non-surgical rat model of foreign body-associated urinary tract infection with Pseudomonas aeruginosa.

Kurosaka Y, Ishida Y, Yamamura E, Takase H, Otani T, Kumon H
Microbiology and immunology 2001;45(1):9-15

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Remembering our teachers.

Kornberg A
The Journal of biological chemistry 2001 Jan 5;276(1):3-11

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Functional analysis of NADPH oxidase in granulocytic cells expressing a delta488-497 gp91(phox) deletion mutant.

Yu L, Cross AR, Zhen L, Dinauer MC
Blood 1999 Oct 1;94(7):2497-504

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Gp91(phox) is the heme binding subunit of the superoxide-generating NADPH oxidase.

Yu L, Quinn MT, Cross AR, Dinauer MC
Proceedings of the National Academy of Sciences of the United States of America 1998 Jul 7;95(14):7993-8

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Allele-specific activation of genetically engineered receptors.

Strader CD, Gaffney T, Sugg EE, Candelore MR, Keys R, Patchett AA, Dixon RA
The Journal of biological chemistry 1991 Jan 5;266(1):5-8

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Characterization of two monoclonal antibodies against cytochrome b558 of human neutrophils.

Verhoeven AJ, Bolscher BG, Meerhof LJ, van Zwieten R, Keijer J, Weening RS, Roos D
Blood 1989 May 1;73(6):1686-94

Flow cytometry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

FACS