DPABH-07980

antibody from Creative Diagnostics

Targeting: ZBTB33 kaiso, WUGSC:H_DJ525N14.1, ZNF-kaiso, ZNF348

No application information provided.

Antibody Data

Product number

DPABH-07980

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-07980, RRID:AB_2510333

Product name

Rabbit Anti-Human ZBTB33 Polyclonal Antibody

Antibody type

Polyclonal

Description

This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-&amp