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- Antibody Data
- Antigen structure
- References [17]
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- Product number
- ALX-803-017-R100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-803-017-R100, RRID:AB_2051436
- Product name
- Furin convertase (human) monoclonal antibody (MON-152)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full length protein
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- MON-152
- Vial size
- 100 μl
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles.
Submitted references Mechanism and significance of cell type-dependent neutralization of flaviviruses.
Proprotein convertase FURIN constrains Th2 differentiation and is critical for host resistance against Toxoplasma gondii.
Proprotein convertase subtilisin/kexin type 3 promotes adipose tissue-driven macrophage chemotaxis and is increased in obesity.
Proprotein convertase furin enhances survival and migration of vascular smooth muscle cells via processing of pro-nerve growth factor.
Generation and characterization of non-competitive furin-inhibiting nanobodies.
Proprotein convertases in human atherosclerotic plaques: the overexpression of FURIN and its substrate cytokines BAFF and APRIL.
Post-endoplasmic reticulum rescue of unstable MHC class I requires proprotein convertase PC7.
Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathway.
IGF-1 increases macrophage motility via PKC/p38-dependent alphavbeta3-integrin inside-out signaling.
Cell-surface processing of pro-ADAMTS9 by furin.
The contribution of arginine residues within the P6-P1 region of alpha 1-antitrypsin to its reaction with furin.
Processing, stability, and receptor binding properties of oligomeric envelope glycoprotein from a primary HIV-1 isolate.
Biosynthesis, distinct post-translational modifications, and functional characterization of lymphoma proprotein convertase.
Endoproteolytic cleavage of its propeptide is a prerequisite for efficient transport of furin out of the endoplasmic reticulum.
Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases.
Modulation of furin-mediated proprotein processing activity by site-directed mutagenesis.
Development and characterization of a panel of monoclonal antibodies against the novel subtilisin-like proprotein processing enzyme furin.
Mukherjee S, Dowd KA, Manhart CJ, Ledgerwood JE, Durbin AP, Whitehead SS, Pierson TC
Journal of virology 2014 Jul;88(13):7210-20
Journal of virology 2014 Jul;88(13):7210-20
Proprotein convertase FURIN constrains Th2 differentiation and is critical for host resistance against Toxoplasma gondii.
Oksanen A, Aittomäki S, Jankovic D, Ortutay Z, Pulkkinen K, Hämäläinen S, Rokka A, Corthals GL, Watford WT, Junttila I, O'Shea JJ, Pesu M
Journal of immunology (Baltimore, Md. : 1950) 2014 Dec 1;193(11):5470-9
Journal of immunology (Baltimore, Md. : 1950) 2014 Dec 1;193(11):5470-9
Proprotein convertase subtilisin/kexin type 3 promotes adipose tissue-driven macrophage chemotaxis and is increased in obesity.
Kappert K, Meyborg H, Fritzsche J, Urban D, Krüger J, Wellnhofer E, Kintscher U, Fleck E, Stawowy P
PloS one 2013;8(8):e70542
PloS one 2013;8(8):e70542
Proprotein convertase furin enhances survival and migration of vascular smooth muscle cells via processing of pro-nerve growth factor.
Urban D, Lorenz J, Meyborg H, Ghosh S, Kintscher U, Kaufmann J, Fleck E, Kappert K, Stawowy P
Journal of biochemistry 2013 Feb;153(2):197-207
Journal of biochemistry 2013 Feb;153(2):197-207
Generation and characterization of non-competitive furin-inhibiting nanobodies.
Zhu J, Declercq J, Roucourt B, Ghassabeh GH, Meulemans S, Kinne J, David G, Vermorken AJ, Van de Ven WJ, Lindberg I, Muyldermans S, Creemers JW
The Biochemical journal 2012 Nov 15;448(1):73-82
The Biochemical journal 2012 Nov 15;448(1):73-82
Proprotein convertases in human atherosclerotic plaques: the overexpression of FURIN and its substrate cytokines BAFF and APRIL.
Turpeinen H, Raitoharju E, Oksanen A, Oksala N, Levula M, Lyytikäinen LP, Järvinen O, Creemers JW, Kähönen M, Laaksonen R, Pelto-Huikko M, Lehtimäki T, Pesu M
Atherosclerosis 2011 Dec;219(2):799-806
Atherosclerosis 2011 Dec;219(2):799-806
Post-endoplasmic reticulum rescue of unstable MHC class I requires proprotein convertase PC7.
Leonhardt RM, Fiegl D, Rufer E, Karger A, Bettin B, Knittler MR
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2985-98
Journal of immunology (Baltimore, Md. : 1950) 2010 Mar 15;184(6):2985-98
Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathway.
Brown SA, Ghosh A, Winkles JA
The Journal of biological chemistry 2010 Jun 4;285(23):17432-41
The Journal of biological chemistry 2010 Jun 4;285(23):17432-41
IGF-1 increases macrophage motility via PKC/p38-dependent alphavbeta3-integrin inside-out signaling.
Furundzija V, Fritzsche J, Kaufmann J, Meyborg H, Fleck E, Kappert K, Stawowy P
Biochemical and biophysical research communications 2010 Apr 9;394(3):786-91
Biochemical and biophysical research communications 2010 Apr 9;394(3):786-91
Cell-surface processing of pro-ADAMTS9 by furin.
Koo BH, Longpré JM, Somerville RP, Alexander JP, Leduc R, Apte SS
The Journal of biological chemistry 2006 May 5;281(18):12485-94
The Journal of biological chemistry 2006 May 5;281(18):12485-94
The contribution of arginine residues within the P6-P1 region of alpha 1-antitrypsin to its reaction with furin.
Dufour EK, Denault JB, Bissonnette L, Hopkins PC, Lavigne P, Leduc R
The Journal of biological chemistry 2001 Oct 19;276(42):38971-9
The Journal of biological chemistry 2001 Oct 19;276(42):38971-9
Processing, stability, and receptor binding properties of oligomeric envelope glycoprotein from a primary HIV-1 isolate.
Staropoli I, Chanel C, Girard M, Altmeyer R
The Journal of biological chemistry 2000 Nov 10;275(45):35137-45
The Journal of biological chemistry 2000 Nov 10;275(45):35137-45
Biosynthesis, distinct post-translational modifications, and functional characterization of lymphoma proprotein convertase.
van de Loo JW, Creemers JW, Bright NA, Young BD, Roebroek AJ, Van de Ven WJ
The Journal of biological chemistry 1997 Oct 24;272(43):27116-23
The Journal of biological chemistry 1997 Oct 24;272(43):27116-23
Endoproteolytic cleavage of its propeptide is a prerequisite for efficient transport of furin out of the endoplasmic reticulum.
Creemers JW, Vey M, Schäfer W, Ayoubi TA, Roebroek AJ, Klenk HD, Garten W, Van de Ven WJ
The Journal of biological chemistry 1995 Feb 10;270(6):2695-702
The Journal of biological chemistry 1995 Feb 10;270(6):2695-702
Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases.
Van de Ven WJ, Roebroek AJ, Van Duijnhoven HL
Critical reviews in oncogenesis 1993;4(2):115-36
Critical reviews in oncogenesis 1993;4(2):115-36
Modulation of furin-mediated proprotein processing activity by site-directed mutagenesis.
Creemers JW, Siezen RJ, Roebroek AJ, Ayoubi TA, Huylebroeck D, Van de Ven WJ
The Journal of biological chemistry 1993 Oct 15;268(29):21826-34
The Journal of biological chemistry 1993 Oct 15;268(29):21826-34
Development and characterization of a panel of monoclonal antibodies against the novel subtilisin-like proprotein processing enzyme furin.
van Duijnhoven HL, Creemers JW, Kranenborg MG, Timmer ED, Groeneveld A, van den Ouweland AM, Roebroek AJ, van de Ven WJ
Hybridoma 1992 Feb;11(1):71-86
Hybridoma 1992 Feb;11(1):71-86
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