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- Product number
- ABIN953010 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8) (AA 3-33), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Protein A column, followed by peptide affinity purification
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 3-33, N-Term
- Vial size
- 0.4 mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Gain-of-function mutation S422L in the KCNJ8-encoded cardiac K(ATP) channel Kir6.1 as a pathogenic substrate for J-wave syndromes.
Lipopolysaccharides up-regulate Kir6.1/SUR2B channel expression and enhance vascular KATP channel activity via NF-kappaB-dependent signaling.
Genes controlling postural changes in blood pressure: comprehensive association analysis of ATP-sensitive potassium channel genes KCNJ8 and ABCC9.
Analysis of two KCNJ11 neonatal diabetes mutations, V59G and V59A, and the analogous KCNJ8 I60G substitution: differences between the channel subtypes formed with SUR1.
Medeiros-Domingo A, Tan BH, Crotti L, Tester DJ, Eckhardt L, Cuoretti A, Kroboth SL, Song C, Zhou Q, Kopp D, Schwartz PJ, Makielski JC, Ackerman MJ
Heart rhythm 2010 Oct;7(10):1466-71
Heart rhythm 2010 Oct;7(10):1466-71
Lipopolysaccharides up-regulate Kir6.1/SUR2B channel expression and enhance vascular KATP channel activity via NF-kappaB-dependent signaling.
Shi W, Cui N, Wu Z, Yang Y, Zhang S, Gai H, Zhu D, Jiang C
The Journal of biological chemistry 2010 Jan 29;285(5):3021-9
The Journal of biological chemistry 2010 Jan 29;285(5):3021-9
Genes controlling postural changes in blood pressure: comprehensive association analysis of ATP-sensitive potassium channel genes KCNJ8 and ABCC9.
Ellis JA, Lamantia A, Chavez R, Scurrah KJ, Nichols CG, Harrap SB
Physiological genomics 2010 Feb 4;40(3):184-8
Physiological genomics 2010 Feb 4;40(3):184-8
Analysis of two KCNJ11 neonatal diabetes mutations, V59G and V59A, and the analogous KCNJ8 I60G substitution: differences between the channel subtypes formed with SUR1.
Winkler M, Lutz R, Russ U, Quast U, Bryan J
The Journal of biological chemistry 2009 Mar 13;284(11):6752-62
The Journal of biological chemistry 2009 Mar 13;284(11):6752-62
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Supportive validation
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- Main image
- Experimental details
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
