Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 17687-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17687-1-AP, RRID:AB_2252483
- Product name
- PJA1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PJA1 antibody (Cat. #17687-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Functional Divergence and Origin of the Vertebrate Praja Family.
OTUB2 Promotes Proliferation and Migration of Hepatocellular Carcinoma Cells by PJA1 Deubiquitylation.
Praja1 RING-finger E3 ubiquitin ligase is a common suppressor of neurodegenerative disease-associated protein aggregation.
Diacylglycerol kinase δ destabilizes serotonin transporter protein through the ubiquitin-proteasome system.
A recurrent PJA1 variant in trigonocephaly and neurodevelopmental disorders.
Praja1 RING-finger E3 ubiquitin ligase suppresses neuronal cytoplasmic TDP-43 aggregate formation.
PJA1 Coordinates with the SMC5/6 Complex To Restrict DNA Viruses and Episomal Genes in an Interferon-Independent Manner.
Praja1 E3 ubiquitin ligase promotes skeletal myogenesis through degradation of EZH2 upon p38α activation.
Onodera W, Kawasaki K, Oishi M, Aoki S, Asahi T
Journal of molecular evolution 2024 Feb;92(1):21-29
Journal of molecular evolution 2024 Feb;92(1):21-29
OTUB2 Promotes Proliferation and Migration of Hepatocellular Carcinoma Cells by PJA1 Deubiquitylation.
Hu G, Yang J, Zhang H, Huang Z, Yang H
Cellular and molecular bioengineering 2022 Jun;15(3):281-292
Cellular and molecular bioengineering 2022 Jun;15(3):281-292
Praja1 RING-finger E3 ubiquitin ligase is a common suppressor of neurodegenerative disease-associated protein aggregation.
Watabe K, Niida-Kawaguchi M, Tada M, Kato Y, Murata M, Tanji K, Wakabayashi K, Yamada M, Kakita A, Shibata N
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Dec;42(6):488-504
Neuropathology : official journal of the Japanese Society of Neuropathology 2022 Dec;42(6):488-504
Diacylglycerol kinase δ destabilizes serotonin transporter protein through the ubiquitin-proteasome system.
Lu Q, Murakami C, Hoshino F, Murakami Y, Sakane F
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Mar;1865(3):158608
Biochimica et biophysica acta. Molecular and cell biology of lipids 2020 Mar;1865(3):158608
A recurrent PJA1 variant in trigonocephaly and neurodevelopmental disorders.
Suzuki T, Suzuki T, Raveau M, Miyake N, Sudo G, Tsurusaki Y, Watanabe T, Sugaya Y, Tatsukawa T, Mazaki E, Shimohata A, Kushima I, Aleksic B, Shiino T, Toyota T, Iwayama Y, Nakaoka K, Ohmori I, Sasaki A, Watanabe K, Hirose S, Kaneko S, Inoue Y, Yoshikawa T, Ozaki N, Kano M, Shimoji T, Matsumoto N, Yamakawa K
Annals of clinical and translational neurology 2020 Jul;7(7):1117-1131
Annals of clinical and translational neurology 2020 Jul;7(7):1117-1131
Praja1 RING-finger E3 ubiquitin ligase suppresses neuronal cytoplasmic TDP-43 aggregate formation.
Watabe K, Kato Y, Sakuma M, Murata M, Niida-Kawaguchi M, Takemura T, Hanagata N, Tada M, Kakita A, Shibata N
Neuropathology : official journal of the Japanese Society of Neuropathology 2020 Dec;40(6):570-586
Neuropathology : official journal of the Japanese Society of Neuropathology 2020 Dec;40(6):570-586
PJA1 Coordinates with the SMC5/6 Complex To Restrict DNA Viruses and Episomal Genes in an Interferon-Independent Manner.
Xu W, Ma C, Zhang Q, Zhao R, Hu D, Zhang X, Chen J, Liu F, Wu K, Liu Y, Wu J
Journal of virology 2018 Nov 15;92(22)
Journal of virology 2018 Nov 15;92(22)
Praja1 E3 ubiquitin ligase promotes skeletal myogenesis through degradation of EZH2 upon p38α activation.
Consalvi S, Brancaccio A, Dall'Agnese A, Puri PL, Palacios D
Nature communications 2017 Jan 9;8:13956
Nature communications 2017 Jan 9;8:13956
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The PJA1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PJA1. This antibody recognizes human,mouse,rat antigen. The PJA1 antibody has been validated for the following applications: ELISA, WB analysis.