Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Other assay [1]
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Validation data
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- Product number
- PA5-40573 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- T-bet Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- Peptide sequence: SIPSPPGPNC QFLGGDHYSP LLPNQYPVPS RFYPDLPGQA KDVVPQAYWL Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 86%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 86%; Rat: 86%
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.5 mg/mL
- Storage
- -20° C, Avoid Freeze/Thaw Cycles
Submitted references VX-765 reduces neuroinflammation after spinal cord injury in mice.
Role of CD4+ T Helper Cells in the Development of BAC-Induced Dry Eye Syndrome in Mice.
[Effect of Huai Qi Huang on asthma in rats and the mechanism research].
CRID3, a blocker of apoptosis associated speck like protein containing a card, ameliorates murine spinal cord injury by improving local immune microenvironment.
Flightless I Alters the Inflammatory Response and Autoantibody Profile in an OVA-Induced Atopic Dermatitis Skin-Like Disease.
Chen J, Chen YQ, Shi YJ, Ding SQ, Shen L, Wang R, Wang QY, Zha C, Ding H, Hu JG, Lü HZ
Neural regeneration research 2021 Sep;16(9):1836-1847
Neural regeneration research 2021 Sep;16(9):1836-1847
Role of CD4+ T Helper Cells in the Development of BAC-Induced Dry Eye Syndrome in Mice.
Ouyang W, Wu Y, Lin X, Wang S, Yang Y, Tang L, Liu Z, Wu J, Huang C, Zhou Y, Zhang X, Hu J, Liu Z
Investigative ophthalmology & visual science 2021 Jan 4;62(1):25
Investigative ophthalmology & visual science 2021 Jan 4;62(1):25
[Effect of Huai Qi Huang on asthma in rats and the mechanism research].
Lu N, Bai Y, Zhao C, Tian L, Wan X, Jin RM
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 2020 Feb;22(2):171-176
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 2020 Feb;22(2):171-176
CRID3, a blocker of apoptosis associated speck like protein containing a card, ameliorates murine spinal cord injury by improving local immune microenvironment.
Chen YQ, Wang SN, Shi YJ, Chen J, Ding SQ, Tang J, Shen L, Wang R, Ding H, Hu JG, Lü HZ
Journal of neuroinflammation 2020 Aug 29;17(1):255
Journal of neuroinflammation 2020 Aug 29;17(1):255
Flightless I Alters the Inflammatory Response and Autoantibody Profile in an OVA-Induced Atopic Dermatitis Skin-Like Disease.
Kopecki Z, Stevens NE, Chong HT, Yang GN, Cowin AJ
Frontiers in immunology 2018;9:1833
Frontiers in immunology 2018;9:1833
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of human liver cells using an anti-T-bet / Tbx21 polyclonal antibody (Product # PA5-40573).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of human skeletal muscle tissue using an anti-T-bet / Tbx21 polyclonal antibody (Product # PA5-40573).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of human kidney tissue using an anti-T-bet / Tbx21 polyclonal antibody (Product # PA5-40573).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 2. Effects of BAC on CD4 + T cell-mediated inflammation in the conjunctiva and CLNs. ( A ) Statistical analysis of the gene expression and protein levels of IFN-gamma in the conjunctiva (CONJ) and CLNs after topical application of BAC. ( B ) Statistical analysis of the gene expression and protein levels of IL-17 in the CONJ and CLNs after topical application of BAC. ( C ) Statistical analysis of gene expression of T-bet and RORgammat in the conjunctiva. ( D ) Representative image of T-bet and RORgammat staining in the conjunctiva. (E) Representative FCM plots of IL-17 + gamma delta + T cells and IFN-gamma + DX5 + NK/NKT cells. The data are shown as the mean +- SD. * P < 0.05, ** P < 0.01 ( n = 5).