Explore
Validate
Learn
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN967673 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-T-Bet antibody
- Antibody type
- Monoclonal
- Antigen
- Human T-bet Peptide
- Description
- Purified from tissue culture supernatant or ascites by affinity chromatography.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- O4-46
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- 4°C
Submitted references The T-box transcription factor T-bet in immunity and autoimmunity.
IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508.
T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.
T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells.
IL-27 and IFN-alpha signal via Stat1 and Stat3 and induce T-Bet and IL-12Rbeta2 in naive T cells.
Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment.
T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells.
T-bet regulates IgG class switching and pathogenic autoantibody production.
Cloning and characterization of a new member of the T-box gene family.
A novel transcription factor, T-bet, directs Th1 lineage commitment.
Peng SL
Cellular & molecular immunology 2006 Apr;3(2):87-95
Cellular & molecular immunology 2006 Apr;3(2):87-95
IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508.
Hwang ES, Hong JH, Glimcher LH
The Journal of experimental medicine 2005 Nov 7;202(9):1289-300
The Journal of experimental medicine 2005 Nov 7;202(9):1289-300
T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.
Hwang ES, Szabo SJ, Schwartzberg PL, Glimcher LH
Science (New York, N.Y.) 2005 Jan 21;307(5708):430-3
Science (New York, N.Y.) 2005 Jan 21;307(5708):430-3
T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells.
Townsend MJ, Weinmann AS, Matsuda JL, Salomon R, Farnham PJ, Biron CA, Gapin L, Glimcher LH
Immunity 2004 Apr;20(4):477-94
Immunity 2004 Apr;20(4):477-94
IL-27 and IFN-alpha signal via Stat1 and Stat3 and induce T-Bet and IL-12Rbeta2 in naive T cells.
Hibbert L, Pflanz S, De Waal Malefyt R, Kastelein RA
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2003 Sep;23(9):513-22
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2003 Sep;23(9):513-22
Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment.
Takeda A, Hamano S, Yamanaka A, Hanada T, Ishibashi T, Mak TW, Yoshimura A, Yoshida H
Journal of immunology (Baltimore, Md. : 1950) 2003 May 15;170(10):4886-90
Journal of immunology (Baltimore, Md. : 1950) 2003 May 15;170(10):4886-90
T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells.
Lugo-Villarino G, Maldonado-Lopez R, Possemato R, Penaranda C, Glimcher LH
Proceedings of the National Academy of Sciences of the United States of America 2003 Jun 24;100(13):7749-54
Proceedings of the National Academy of Sciences of the United States of America 2003 Jun 24;100(13):7749-54
T-bet regulates IgG class switching and pathogenic autoantibody production.
Peng SL, Szabo SJ, Glimcher LH
Proceedings of the National Academy of Sciences of the United States of America 2002 Apr 16;99(8):5545-50
Proceedings of the National Academy of Sciences of the United States of America 2002 Apr 16;99(8):5545-50
Cloning and characterization of a new member of the T-box gene family.
Zhang WX, Yang SY
Genomics 2000 Nov 15;70(1):41-8
Genomics 2000 Nov 15;70(1):41-8
A novel transcription factor, T-bet, directs Th1 lineage commitment.
Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH
Cell 2000 Mar 17;100(6):655-69
Cell 2000 Mar 17;100(6):655-69
No comments: Submit comment
No validations: Submit validation data