Antibody data
- Antibody Data
- Antigen structure
- References [196]
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- Product number
- 28205-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- BDNF antibody
- Antibody type
- Polyclonal
- Description
- BDNF antibody (Cat. #28205-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references HIIT-induced lactate/GPR81 signaling with dual branches converging on ERK1/2 contributes to hippocampal synaptic remodeling and memory improvement.
Neural stem cell transplantation attenuates cognitive decline and neuroinflammation in a mouse model of Alzheimer's disease with chronic cerebral hypoperfusion.
γδTreg/γδTh17 Cell Imbalance Drives Xanthine-Mediated Metabolic Dysfunction in Restraint Stress-Induced Anxiety-Like Behavior.
Guaiane-type sesquiterpenoids from patchouli oil and their potential anti-depressive effects.
Integrating neurotrophic and anti-inflammatory pathways: press-needle acupuncture as a multi-target therapy for adolescent depression.
Si-Ni-San alleviates depressive-like behaviors in adolescent male mice by restoring DRN-NAc serotonergic circuit function and 5-HT4R-dependent synaptic plasticity.
Schwann-endothelial crosstalk in neurovascularized cell sheets induced host CGRP release to drive mandibular bone regeneration.
Cycloastragenol protected hippocampal CA1 neurons by regulating redox homeostasis and alleviated cognitive impairment following cerebral ischemia-reperfusion.
Perinatal hyperandrogenization and immune activation in rodents model subtypes of autism.
Mechanistic insights into the effects of Norisoboldine on intestinal immunity and neuroinflammation in a mouse model of slow transit constipation with depression.
Mechanism of Atractylodis Rhizoma in improving cognitive dysfunction in Alzheimer's disease by regulating the cAMP/CREB/BDNF pathway.
Efficacy and Mechanisms Underlying MRI-guided High-definition Transcranial Direct Current Stimulation Combined With Computerized Cognitive Remediation Therapy for Improving Cognitive Impairments in Schizophrenia: Study Protocol for a Randomized Controlled Trial.
Chitosan-rapamycin carbon dots rejuvenate autologous Sca-1⁺ stem cells paracrine function for neuroprotection in normal tension glaucoma.
Effects of Short-Term Exposure to Polystyrene Nanoplastics on the Nervous System: Calcium Homeostasis, BDNF and Synaptic Plasticity.
Yueju pill exerts rapid antidepressant effects via sequential activation of hippocampal GLP-1 receptor and PACAP signaling in mice.
Yiqi Yangxin Anshen Oral liquid ameliorates anxiety-like behaviors and learning-memory impairment in sleep deprivation rats via maintaining neurotransmitters homeostasis and regulation of cAMP/CREB signaling pathway.
Kai-Xin-San Has Antidepressant-Like Effect in Tricyclic Antidepressant Treatment Resistant Animal Model by Rebalancing Tryptophan Metabolism.
Aerobic exercise and gut flora: a key link to improved cognitive impairment in mice with Parkinson's disease.
Immune imbalance underlying depressive symptoms in COPD patients: a study based on BDNF, PD-1, MMP-9, and inflammatory cytokines.
The Role of SIRT1-BDNF Signaling Pathway in Fluoride-Induced Toxicity for Glial BV-2 Cells.
High-Calorie Diet During Pregnancy Leads to Muscular Fibrosis and Neuromuscular Damage in Offspring Mice.
Overexpression of Rap1B alleviate central precocious puberty and neurodevelopmental damage.
Acupuncture improves depressive-like behaviors in CUMS rats by modulating lateral habenula synaptic plasticity via the BDNF/ERK/mTOR pathway.
Transcriptomic Investigation of FoxM1-Mediated Neuroprotection by hAEC-Derived Exosomes in an In Vitro Ischemic Stroke Model.
Mechanisms of Senegenin in Regulating Oxidative Stress and Mitochondria Damage for Neuroprotection in Insomnia: Evidence from In Vivo and In Vitro Models.
Flexible Living Artificial Dura Mater for Efficient Therapy of Central Nervous System Injury Based on Neuronal Differentiation and Neuroprotective A2 Astrocyte Activation.
Inhibition of spreading depolarizations by targeting GABA(A) receptors and voltage-gated sodium channels improves neurological deficits in rats with traumatic brain injury.
Exercise-induced weight loss modulates brain iron and omega-3 fatty acid metabolism in middle-aged obese rats.
Migration of CD8 + TSCM cells into intestine via PPBP-CXCR2 axis increases host stress susceptibility by inhibiting gut microbiome-derived homovanillic acid.
Design of anti-depressant phosphodiester amino acidic Keap1-Nrf2 protein-protein interaction inhibitors.
Identification of preventive biomarkers associated with circadian rhythms in traumatic brain injury-mediated depression: Expression of SERPINE1 protein and bioinformatics analysis.
Astragalin alleviates lipopolysaccharide-induced depressive-like behavior in mice by preserving blood-brain barrier integrity and suppressing neuroinflammation.
Semaglutide and High-Intensity Interval Exercise Attenuate Cognitive Impairment in Type 2 Diabetic Mice via BDNF Modulation.
Bone-brain communication mediates the amelioration of Polgonatum cyrtonema Hua polysaccharide on fatigue in chronic sleep-deprived mice.
Allium Macrostemon Bge. Attenuates the Cognitive Decline of Aging Mice by Enhancing BDNF/TrkB Pathway.
Muscone enhances synaptic function in vascular dementia through activating BDNF-TrkB-NP2 signaling pathway.
Resolvin D1 accelerates resolution of neuroinflammation by inhibiting microglia activation through the BDNF/TrkB signaling pathway.
Senegenin regulates the mechanism of insomnia through the Keap1/Nrf2/PINK1/Parkin pathway mediated by GAD67.
TSPO activation ameliorates maternal immune activation induced PV interneuron deficits via BDNF/TrkB signaling.
GPR43 regulates mitochondrial apoptosis through the cyclophilin D pathway in Alzheimer's disease.
Thioredoxin-1 Downregulation in the SNpc Exacerbates the Cognitive Impairment Induced by MPTP.
Kai-Xin-San ameliorates fluoxetine-resistant depressive-like behaviors by modulating tryptophan-kynurenine metabolic homeostasis in a rodent model.
Hydrogel system with growth cone-targeted hydroxyapatite nanorods: Regulating calcium signals for peripheral nerve injury repair.
Magnolol acts as a neurorestorative agent in an A(β1‑42)‑induced mouse model of Alzheimer's disease.
Liangxue Tongyu Prescription exerts neuroprotection by regulating the microbiota-gut-brain axis of rats with acute intracerebral hemorrhage.
Pink1/Parkin signaling mediates pineal mitochondrial autophagy dysfunction and its biological role in a comorbid rat model of depression and insomnia.
TREM2 alleviates long-term cognitive dysfunction after subarachnoid hemorrhage in mice by attenuating hippocampal neuroinflammation via PI3K/Akt signaling pathway.
Xiao-Chai-Hu-Tang Ameliorates Depressive Symptoms via Modulating Neuro-Endocrine Network in Chronic Unpredictable Mild Stress-Induced Mice.
Jiawei Kongsheng Zhenzhong Pill (JKZP) Alleviates Chronic Cerebral Hypoperfusion-Induced Hippocampal Synaptic Damage via S100A10/tPA/BDNF Pathway.
Syringa oblata Lindl extract alleviated corticosterone-induced depression via the cAMP/PKA-CREB-BDNF pathway.
Exploring the effect and mechanism of action of Jinlida granules (JLD) in the treatment of diabetes-associated cognitive impairment based on network pharmacology with experimental validation.
Characterizing stroke-related cellular changes in the surviving neurons of mouse ischemic stroke.
Neuromodulatory Effects of Arecoline on Anxiety-like Behavior in Mice Exposed to Chronic Unpredictable Mild Stress.
Analgesic Mechanism of Emodin in Neuropathic Pain Through Inhibiting P2X4 Purinoceptor Signaling.
Different Fasting Methods Combined With Running Exercise Regulate Glucose Metabolism via AMPK/SIRT1/BDNF Pathway in Mice.
COG1410 Alleviated Chronic Sleep Deprivation-Induced Memory Loss by Regulating Microglial Phagocytosis and Inhibiting Hippocampal Inflammation.
Low-intensity millimeter waves ameliorate cognitive impairment induced by chronic REM sleep deprivation in rats by regulating CaMKII-CREB-BDNF pathway.
Alpha‑Asarone Ameliorates Neuronal Injury After Ischemic Stroke and Hemorrhagic Transformation by Attenuating Blood-Brain Barrier Destruction, Promoting Neurogenesis, and Inhibiting Neuroinflammation.
Understanding the Antidepressant Mechanisms of Acupuncture: Targeting Hippocampal Neuroinflammation, Oxidative Stress, Neuroplasticity, and Apoptosis in CUMS Rats.
Acoustic Enrichment Prevents Early Life Stress-Induced Disruptions in Sound Azimuth Processing.
Adult Neurogenesis Is Regulated by the Endocannabinoid and Kisspeptin Systems.
High urea promotes mitochondrial fission and functional impairments in astrocytes inducing anxiety-like behavior in chronic kidney disease mice.
Effect of histone demethylase KDM5B on long-term cognitive impairment in neonatal rats induced by sevoflurane.
Enriched oxygen improves age-related cognitive impairment through enhancing autophagy.
Asiaticoside improves depressive-like behavior in mice with chronic unpredictable mild stress through modulation of the gut microbiota.
Anti-neuroinflammatory effect of hydroxytyrosol: a potential strategy for anti-depressant development.
Nicotine inhalant via E-cigarette facilitates sensorimotor function recovery by upregulating neuronal BDNF-TrkB signalling in traumatic brain injury.
NMC-4 Ameliorates Depression-Like Behavior and Neuroinflammation Caused by Chronic Unpredictable Mild Stress.
Neuroinflammation inhibition and neuroprotective effects of purpurin, a potential anti-AD compound, screened via network proximity and gene enrichment analyses.
GOS enhances BDNF-mediated mammary gland development in pubertal mice via the gut-brain axis.
MiR-204 regulates autophagy and cell viability by targeting BDNF and inhibiting the NTRK2-dependent PI3K/Akt/mTOR pathway in a human granulosa cell line exposed to bisphenol A.
Effects on Synaptic Plasticity Markers in Fetal Mice and HT22 Neurons upon F-53B Exposure: The Role of PKA Cytoplasmic Retention.
Treatment of Parkinson's disease model with human umbilical cord mesenchymal stem cell-derived exosomes loaded with BDNF.
Exploring miR-21 as a key regulator in two distinct approaches of bone marrow stromal cells differentiation into Schwann-like cells.
Particulate matter (PM(10)) exacerbates on MK-801-induced schizophrenia-like behaviors through the inhibition of ERK-CREB-BDNF signaling pathway.
Mecp2 Deficiency in Peripheral Sensory Neuron Improves Cognitive Function by Enhancing Hippocampal Dendritic Spine Densities in Mice.
Deciphering the antidepressant effects of Rosa damascena essential oil mediated through the serotonergic synapse signaling pathway.
Human iPSC-derived endothelial cells promote CNS remyelination via BDNF and mTORC1 pathway.
Electroacupuncture ameliorates chronic unpredictable mild stress-induced depression-like behavior and cognitive impairment through suppressing oxidative stress and neuroinflammation in rats.
Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke.
The role of NF-κB signaling pathway in reactive astrocytes among neurodegeneration after methamphetamine exposure by integrated bioinformatics.
Tong-Qiao-Huo-Xue Decoction promotes synaptic remodeling via cAMP/PKA/CREB pathway in vascular dementia rats.
Analysis of microisolated frontal cortex excitatory layer III and V pyramidal neurons reveals a neurodegenerative phenotype in individuals with Down syndrome.
Comparison of CUMS at different pregnancy stages, maternal separation, and their effects on offspring in postpartum depression mouse models.
5Z-7-Oxozaenol attenuates cuprizone-induced demyelination in mice through microglia polarization regulation.
Dietary High-Fat Promotes Cognitive Impairment by Suppressing Mitophagy.
Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis.
Integrating Network Pharmacology, Molecular Docking and Pharmacological Evaluation for Exploring the Polyrhachis vicina Rogers in Ameliorating Depression.
Bacteroides vulgatus alleviates dextran sodium sulfate-induced colitis and depression-like behaviour by facilitating gut-brain axis balance.
Dopamine receptor 1 on CaMKII-positive neurons within claustrum mediates adolescent cocaine exposure-induced anxiety-like behaviors and electro-acupuncture therapy.
Body Weight Support Treadmill Training Combined With Sciatic Nerve Electrical Stimulation Ameliorating Motor Function by Enhancing PI3K/Akt Proteins Expression via BDNF/TrkB Signaling Pathway in Rats with Spinal Cord Injury.
Dexmedetomidine alleviates propofol-induced neural injury in developing rats.
The Combination of Citicoline and Nicotinamide Mononucleotide Induces Neurite Outgrowth and Mitigates Vascular Cognitive Impairment via SIRT1/CREB Pathway.
Antidepressant effects of 70% ethanolic extract of Lonicerae japonicae flos and it contained chlorogenic acid via upregulation of BDNF-TrkB pathway in the hippocampus of mice.
Manganese-enhanced magnetic resonance assessment of changes in hippocampal neural function after the treatment of radiation-induced brain injury with bone marrow mesenchymal stem cells.
The role of EndophilinA1 in chronic unpredicted mild stress-induced depression model mice.
The total alkaloids of Sophora alopecuroides L. improve depression-like behavior in mice via BDNF-mediated AKT/mTOR signaling pathway.
NMN Alleviates NP-Induced Learning and Memory Impairment Through SIRT1 Pathway in PC-12 Cell.
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway.
Prenatal alcohol exposure enhanced alcohol preference and susceptibility to PTSD in a sex-dependent manner through the synaptic HCN1 channel.
A whole transcriptome profiling analysis for antidepressant mechanism of Xiaoyaosan mediated synapse loss via BDNF/trkB/PI3K signal axis in CUMS rats.
Inhibition of TREM-1 ameliorates Lipopolysaccharide-induced depressive-like behaviors by alleviating neuroinflammation in the PFC via PI3K/Akt signaling pathway.
Modulatory effect of n-3 polyunsaturated fatty acids on depressive-like behaviors in rats with chronic sleep deprivation: potential involvement of melatonin receptor pathway and brain lipidome.
Omega-3 Polyunsaturated Fatty Acid Eicosapentaenoic Acid or Docosahexaenoic Acid Improved Ageing-Associated Cognitive Decline by Regulating Glial Polarization.
BDNF guides neural stem cell-derived axons to ventral interneurons and motor neurons after spinal cord injury.
Antidepression of Xingpijieyu formula targets gut microbiota derived from depressive disorder.
Neural stem cell-derived exosome as a nano-sized carrier for BDNF delivery to a rat model of ischemic stroke.
Tunicamycin induces depression-like behaviors in male rats, accompanied by initiated chaperon-mediated autophagy and decreased synaptic protein expression in the hippocampus.
Matrine alleviates depressive-like behaviors via modulating microbiota-gut-brain axis in CUMS-induced mice.
MICROGLIA AND INFILTRATING T-CELLS ADOPT LONG-TERM, AGE-SPECIFIC, TRANSCRIPTIONAL CHANGES AFTER TRAUMATIC BRAIN INJURY IN MICE.
Metformin Improves Comorbid Depressive Symptoms in Mice with Allergic Rhinitis by Reducing Olfactory Bulb Damage.
TRIM69 suppressed the anoikis resistance and metastasis of gastric cancer through ubiquitin‒proteasome-mediated degradation of PRKCD.
Lactate Mediates High-Intensity Interval Training-Induced Promotion of Hippocampal Mitochondrial Function through the GPR81-ERK1/2 Pathway.
Synergistic effects of lipopolysaccharide and rotenone on dopamine neuronal damage in rats.
The effects of acupuncture on depression by regulating BDNF-related balance via lateral habenular nucleus BDNF/TrkB/CREB signaling pathway in rats.
Aripiprazole combined with nerve growth factor improves cognitive function in mice with schizophrenia model.
Aerobic Exercise Facilitates the Nuclear Translocation of SREBP2 by Activating AKT/SEC24D to Contribute Cholesterol Homeostasis for Improving Cognition in APP/PS1 Mice.
Benzene, 1,2,4-Trimethoxy-5-(2-Methyl-1-Propen-1-yl) Attenuates D-galactose/AlCl(3)-induced Cognitive Impairment by Inhibiting Inflammation, Apoptosis, and improving Expression of Memory-Related Proteins.
Treatment Combining Focused Ultrasound with Gastrodin Alleviates Memory Deficit and Neuropathology in an Alzheimer's Disease-Like Experimental Mouse Model.
Cinnamic Acid Improved Lipopolysaccharide-Induced Depressive-Like Behaviors by Inhibiting Neuroinflammation and Oxidative Stress in Mice.
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Enhanced effect of combining bone marrow mesenchymal stem cells (BMMSCs) and pulsed electromagnetic fields (PEMF) to promote recovery after spinal cord injury in mice.
Antidepressant effect of Jujuboside A on corticosterone-induced depression in mice.
N-linoleyltyrosine protects neurons against Aβ(1-40)-induced cell toxicity via autophagy involving the CB(2)/AMPK/mTOR/ULK1 pathway.
Dietary Salt Disrupts Tricarboxylic Acid Cycle and Induces Tau Hyperphosphorylation and Synapse Dysfunction during Aging.
Cognitive-exercise dual-task intervention ameliorates cognitive decline in natural aging rats through reducing oxidative stress and enhancing synaptic plasticity.
Sodium butyrate exerts antioxidant stress effects and attenuates Aβ(25-35)-induced cytotoxicity in PC12 cells.
Effect of dendrobium mixture in alleviating diabetic cognitive impairment associated with regulating gut microbiota.
IL-33 in the basolateral amygdala integrates neuroinflammation into anxiogenic circuits via modulating BDNF expression.
Estrogen-related Receptor α (ERRα) Functions in The Hypoxic Injury of Microglial Cells.
Involvement of the BDNF-TrkB-KCC2 pathway in neuropathic pain after brachial plexus avulsion.
Fish oil ameliorates neuropsychiatric behaviors and gut dysbiosis by elevating selected microbiota-derived metabolites and tissue tight junctions in rats under chronic sleep deprivation.
Regulation of the kynurenine/serotonin pathway by berberine and the underlying effect in the hippocampus of the chronic unpredictable mild stress mice.
Oral squamous cell carcinoma-released brain-derived neurotrophic factor contributes to oral cancer pain by peripheral tropomyosin receptor kinase B activation.
Multiple Mild Stimulations Reduce Membrane Distribution of CX3CR1 Promoted by Annexin a1 in Microglia to Attenuate Excessive Dendritic Spine Pruning and Cognitive Deficits Caused by a Transient Ischemic Attack in Mice.
Reactive Oxygen Species Scavenging Functional Hydrogel Delivers Procyanidins for the Treatment of Traumatic Brain Injury in Mice.
Low-dose S-ketamine exerts antidepressant-like effects via enhanced hippocampal synaptic plasticity in postpartum depression rats.
Injectable hyaluronic acid hydrogel loaded with BMSC and NGF for traumatic brain injury treatment.
Bupivacaine reduces GlyT1 expression by potentiating the p-AMPKα/BDNF signalling pathway in spinal astrocytes of rats.
Inhibition of Geranylgeranylacetone on cholecystokinin-B receptor, BDNF and dopamine D1 receptor induced by morphine.
Preparation, Characterization, Evaluation of Neuroprotective Effect, and Related Mechanisms of Phosphatidylserine Emulsion in 5- and 12-Week Old Mice.
Involvement of the gut-brain axis in vascular depression via tryptophan metabolism: A benefit of short chain fatty acids.
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.
Exposure to dibutyl phthalate adsorbed to multi-walled carbon nanotubes causes neurotoxicity in mice by inducing the release of BDNF.
Necrostatin-1 Against Sevoflurane-Induced Cognitive Dysfunction Involves Activation of BDNF/TrkB Pathway and Inhibition of Necroptosis in Aged Rats.
Maternal stress programs a demasculinization of glutamatergic transmission in stress-related brain regions of aged rats.
Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice.
Curcumin Relieves Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior through the PGC-1α/FNDC5/BDNF Pathway.
Edaravone Alleviated Propofol-Induced Neurotoxicity in Developing Hippocampus by mBDNF/TrkB/PI3K Pathway.
Network Pharmacology-Based and Experimental Identification of the Effects of Paeoniflorin on Major Depressive Disorder.
An Integrative Pharmacology-Based Strategy to Uncover the Mechanism of Xiong-Pi-Fang in Treating Coronary Heart Disease with Depression.
Tetrahydropalmatine Regulates BDNF through TrkB/CAM Interaction to Alleviate the Neurotoxicity Induced by Methamphetamine.
Merazin Hydrate Produces Rapid Antidepressant Effects Depending on Activating mTOR Signaling by Upregulating Downstream Synaptic Proteins in the Hippocampus.
The role of SIRT1 in the basolateral amygdala in depression-like behaviors in mice.
Dopamine receptor 2 downregulation and brain-derived neurotrophic factor upregulation in the paraventricular nucleus are correlated with brown adipose tissue thermogenesis in rats with bilateral substantia nigra lesions.
Chronic ethanol exposure induced depressive-like behavior in male C57BL/6 N mice by downregulating GluA1.
Cardiac glycosaminoglycans and structural alterations during chronic stress-induced depression-like behavior in mice.
Crocetin ameliorates chronic restraint stress-induced depression-like behaviors in mice by regulating MEK/ERK pathways and gut microbiota.
Neuroprotective effects of bone marrow Sca-1(+) cells against age-related retinal degeneration in OPTN E50K mice.
Caloric restriction ameliorates high-fat diet induced cognitive deficits through attenuating neuroinflammation via the TREM2-PI3K/AKT signaling pathway.
The protective function of taurine on pesticide-induced permanent neurodevelopmental toxicity in juvenile rats.
Rapid antidepressant-like effect of Fructus Aurantii depends on cAMP-response element binding protein/Brain-derived neurotrophic facto by mediating synaptic transmission.
Water treadmill training protects the integrity of the blood-spinal cord barrier following SCI via the BDNF/TrkB-CREB signalling pathway.
Meranzin hydrate elicits antidepressant effects and restores reward circuitry.
Myrtenol improves brain damage and promotes angiogenesis in rats with cerebral infarction by activating the ERK1/2 signalling pathway.
Inhibition of P2X4R attenuates white matter injury in mice after intracerebral hemorrhage by regulating microglial phenotypes.
Sodium Butyrate Protects N2a Cells against Aβ Toxicity In Vitro.
Excessive Treadmill Training Enhances Brain-Specific MicroRNA-34a in the Mouse Hippocampus.
IRF8 is crucial for the nicotine withdrawal-induced hyperalgesia in mice.
PKA-Dependent Membrane Surface Recruitment of CI-AMPARs Is Crucial for BCP-Mediated Protection Against Post-acute Ischemic Stroke Cognitive Impairment.
Chaiyu-Dixian Formula Exerts Protective Effects on Ovarian Follicular Abnormal Development in Chronic Unpredictable Mild Stress (CUMS) Rat Model.
DL0410 attenuates oxidative stress and neuroinflammation via BDNF/TrkB/ERK/CREB and Nrf2/HO-1 activation.
Anti-Alzheimer's disease activity of secondary metabolites from Xanthoceras sorbifolia Bunge.
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Colocalization of dopamine receptors in BDNF-expressing peptidergic neurons in the paraventricular nucleus of rats.
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Curcumin protects rat hippocampal neurons against pseudorabies virus by regulating the BDNF/TrkB pathway.
Catalpol Enhances Neurogenesis And Inhibits Apoptosis Of New Neurons Via BDNF, But Not The BDNF/Trkb Pathway.
RGS4 Regulates Proliferation And Apoptosis Of NSCLC Cells Via microRNA-16 And Brain-Derived Neurotrophic Factor.
Melatonin ameliorates cuprizone-induced reduction of hippocampal neurogenesis, brain-derived neurotrophic factor, and phosphorylation of cyclic AMP response element-binding protein in the mouse dentate gyrus.
Melatonin alleviates cognition impairment by antagonizing brain insulin resistance in aged rats fed a high-fat diet.
Partially Hydrolyzed Guar Gum Attenuates d-Galactose-Induced Oxidative Stress and Restores Gut Microbiota in Rats.
A dual-enzymatically cross-linked injectable gelatin hydrogel loaded with BMSC improves neurological function recovery of traumatic brain injury in rats.
Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice.
Apelin-13 ameliorates chronic water-immersion restraint stress-induced memory performance deficit through upregulation of BDNF in rats.
Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats.
Improvement of motor function induced by skeletal muscle contraction in spinal cord-injured rats.
Improvement in neurogenesis and memory function by administration of Passiflora incarnata L. extract applied to sleep disorder in rodent models.
Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats.
Protective effects of astaxanthin on subarachnoid hemorrhage-induced early brain injury: Reduction of cerebral vasospasm and improvement of neuron survival and mitochondrial function.
Proteomic profiling of the neurons in mice with depressive-like behavior induced by corticosterone and the regulation of berberine: pivotal sites of oxidative phosphorylation.
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
The Anticonvulsant Effects of Baldrinal on Pilocarpine-Induced convulsion in Adult Male Mice.
Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions.
Bacopa monnieri extract improves novel object recognition, cell proliferation, neuroblast differentiation, brain-derived neurotrophic factor, and phosphorylation of cAMP response element-binding protein in the dentate gyrus.
Bian X, Shang Q, Zhu L, Liu J, Wu M, Li J, Lou S
Frontiers in cell and developmental biology 2026;14:1699042
Frontiers in cell and developmental biology 2026;14:1699042
Neural stem cell transplantation attenuates cognitive decline and neuroinflammation in a mouse model of Alzheimer's disease with chronic cerebral hypoperfusion.
Lu Z, Zhou H, Tang H, Luo S, Wang J, Zheng X, Hu Y, Qin Q, Yang C, Mo S, Huang X, Tang L, Huang B, Xu W, Nong J, Gan G, Qin D, Peng Z, Jian C, Liu X, Li X, Shang J
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 May;46(5):1219-1237
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2026 May;46(5):1219-1237
γδTreg/γδTh17 Cell Imbalance Drives Xanthine-Mediated Metabolic Dysfunction in Restraint Stress-Induced Anxiety-Like Behavior.
Xue X, Tang C, Yan N, Lai X, Li Q, Li E
Cell biology international 2026 Mar;50(3):e70149
Cell biology international 2026 Mar;50(3):e70149
Guaiane-type sesquiterpenoids from patchouli oil and their potential anti-depressive effects.
Zheng Q, Zhu H, Yang HP, Peng C, Wu GX, Zhou QM, Xiong L
Phytochemistry 2026 Mar;243:114738
Phytochemistry 2026 Mar;243:114738
Integrating neurotrophic and anti-inflammatory pathways: press-needle acupuncture as a multi-target therapy for adolescent depression.
Zhang H, Rong Y, Ning R, Yan Z, Zhao Y, Chen Y
The International journal of neuroscience 2026 Mar 12;:1-16
The International journal of neuroscience 2026 Mar 12;:1-16
Si-Ni-San alleviates depressive-like behaviors in adolescent male mice by restoring DRN-NAc serotonergic circuit function and 5-HT4R-dependent synaptic plasticity.
Wang Y, Liu Z, Wu J, Ye L, Huang C, Xuan Y, Liang H, Deng D, Bai S, Yang L, An L, Liu Z, Shi Y, Zhang R, Zhao J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158088
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158088
Schwann-endothelial crosstalk in neurovascularized cell sheets induced host CGRP release to drive mandibular bone regeneration.
Wang Z, Li L, Fu Y, Zhang Z, Liu J, Yang X, Bao L, Liu S, Wei F
Journal of orthopaedic translation 2026 Jan;56:101046
Journal of orthopaedic translation 2026 Jan;56:101046
Cycloastragenol protected hippocampal CA1 neurons by regulating redox homeostasis and alleviated cognitive impairment following cerebral ischemia-reperfusion.
Gao S, Zhu S, Qu T, Zou J, Yin L, Wang X, Yin X, Tong L, Li W
Brain research bulletin 2026 Jan;234:111689
Brain research bulletin 2026 Jan;234:111689
Perinatal hyperandrogenization and immune activation in rodents model subtypes of autism.
Burke FF, Randell AM, Sparkes KM, Salia S, Hinks M, Martin Y, Porter Z, Hynes C, Maekawa AS, Sled J, Wilson DR, Kaushik DK, Kakumani PK, Walling SG, Cahill LS, Swift-Gallant A
Translational psychiatry 2026 Jan 30;16(1)
Translational psychiatry 2026 Jan 30;16(1)
Mechanistic insights into the effects of Norisoboldine on intestinal immunity and neuroinflammation in a mouse model of slow transit constipation with depression.
Wu B, Wu J, Bai X, Zhou Q, Wang X
Journal of ethnopharmacology 2026 Jan 10;354:120479
Journal of ethnopharmacology 2026 Jan 10;354:120479
Mechanism of Atractylodis Rhizoma in improving cognitive dysfunction in Alzheimer's disease by regulating the cAMP/CREB/BDNF pathway.
Xu X, Zhao Y, Ma H, Hu Y, Yu L, Su Y, Song J, Xie Z, Zhang Z, Wang P
International immunopharmacology 2026 Jan 1;168(Pt 2):115923
International immunopharmacology 2026 Jan 1;168(Pt 2):115923
Efficacy and Mechanisms Underlying MRI-guided High-definition Transcranial Direct Current Stimulation Combined With Computerized Cognitive Remediation Therapy for Improving Cognitive Impairments in Schizophrenia: Study Protocol for a Randomized Controlled Trial.
Wei Y, He S, Luo P, Liu R, Su H, Shen Z, Feng S, Wu Y, Ji G, Zheng W, Wang F, Wang C
Alpha psychiatry 2026 Feb;27(1):46768
Alpha psychiatry 2026 Feb;27(1):46768
Chitosan-rapamycin carbon dots rejuvenate autologous Sca-1⁺ stem cells paracrine function for neuroprotection in normal tension glaucoma.
Du M, Guo F, Liu X, Zhang S, Zhang D, Qiu L, Zhang J, Li B, Yuan H
Stem cell research & therapy 2026 Feb 23;17(1)
Stem cell research & therapy 2026 Feb 23;17(1)
Effects of Short-Term Exposure to Polystyrene Nanoplastics on the Nervous System: Calcium Homeostasis, BDNF and Synaptic Plasticity.
Zhao Y, Yan L, Wei Y, Ma J, Chen J, Liu X, Mi Y, Wang B, Zhang L, Tian L, Lin B
Toxics 2026 Feb 17;14(2)
Toxics 2026 Feb 17;14(2)
Yueju pill exerts rapid antidepressant effects via sequential activation of hippocampal GLP-1 receptor and PACAP signaling in mice.
Xing S, Peng Y, Wang Y, Wu C, Han M, Xie H, Chen G, Zhang H
Journal of ethnopharmacology 2026 Aug 10;367:121767
Journal of ethnopharmacology 2026 Aug 10;367:121767
Yiqi Yangxin Anshen Oral liquid ameliorates anxiety-like behaviors and learning-memory impairment in sleep deprivation rats via maintaining neurotransmitters homeostasis and regulation of cAMP/CREB signaling pathway.
Yu KJ, Yang GZ, Huang J, Tan F, Chen XB, Xu BY, OuYang J, Wang MX, Zhou H, Yang ZM, Xu W
Journal of ethnopharmacology 2026 Aug 10;367:121693
Journal of ethnopharmacology 2026 Aug 10;367:121693
Kai-Xin-San Has Antidepressant-Like Effect in Tricyclic Antidepressant Treatment Resistant Animal Model by Rebalancing Tryptophan Metabolism.
Yao L, Chen C, Jing R, Wang CC, Wang YB, Li X, Mu LH, Yin H, Liu P, Hu Y
Chinese journal of integrative medicine 2026 Apr;32(4):322-331
Chinese journal of integrative medicine 2026 Apr;32(4):322-331
Aerobic exercise and gut flora: a key link to improved cognitive impairment in mice with Parkinson's disease.
Shan WP, Yan SL, Guo YY, Yang HK, Wang JC, Xiang J
Frontiers in aging neuroscience 2025;17:1630003
Frontiers in aging neuroscience 2025;17:1630003
Immune imbalance underlying depressive symptoms in COPD patients: a study based on BDNF, PD-1, MMP-9, and inflammatory cytokines.
Liu S, Dong J, Huang W, Yan J
Frontiers in medicine 2025;12:1606630
Frontiers in medicine 2025;12:1606630
The Role of SIRT1-BDNF Signaling Pathway in Fluoride-Induced Toxicity for Glial BV-2 Cells.
Yang B, Wang F, Yang X, Yuan X, Yang Y, Chen X, Tian T, Chen F, Tang D, He Z, Liu Y, Li Y
Biological trace element research 2025 Sep;203(9):4789-4806
Biological trace element research 2025 Sep;203(9):4789-4806
High-Calorie Diet During Pregnancy Leads to Muscular Fibrosis and Neuromuscular Damage in Offspring Mice.
Son JS, Chae SA, Chun YH, Wang H, Jiang Z, Du M
Journal of cachexia, sarcopenia and muscle 2025 Oct;16(5):e70027
Journal of cachexia, sarcopenia and muscle 2025 Oct;16(5):e70027
Overexpression of Rap1B alleviate central precocious puberty and neurodevelopmental damage.
Liu X, Zeng L
Cellular signalling 2025 Oct;134:111941
Cellular signalling 2025 Oct;134:111941
Acupuncture improves depressive-like behaviors in CUMS rats by modulating lateral habenula synaptic plasticity via the BDNF/ERK/mTOR pathway.
Yan S, Liu J, Zhang T, Li J, Zeng J, Li M, Aslam MS, Shen J, Tong T, You Z, Liu S, Li P, Li J, Gong K, Wei S, Hao C, Meng X
Molecular brain 2025 Oct 8;18(1):77
Molecular brain 2025 Oct 8;18(1):77
Transcriptomic Investigation of FoxM1-Mediated Neuroprotection by hAEC-Derived Exosomes in an In Vitro Ischemic Stroke Model.
Wang D, Liu J, Wu L, Yang X, Fang Z, Sun Z, Chen D
Biology 2025 Oct 7;14(10)
Biology 2025 Oct 7;14(10)
Mechanisms of Senegenin in Regulating Oxidative Stress and Mitochondria Damage for Neuroprotection in Insomnia: Evidence from In Vivo and In Vitro Models.
Jia H, Liang Z, Yan D, Chen X, Liang R, Wu J, Zhang X
Molecular neurobiology 2025 Nov;62(11):13917-13932
Molecular neurobiology 2025 Nov;62(11):13917-13932
Flexible Living Artificial Dura Mater for Efficient Therapy of Central Nervous System Injury Based on Neuronal Differentiation and Neuroprotective A2 Astrocyte Activation.
Yang H, Liu H, Lou C, Han M, Sun Z, Su Y, Bian K, Zhao D, Li Y, Sang Y, Liu C, Geng Z, Liu H, Qiu J
Advanced materials (Deerfield Beach, Fla.) 2025 Nov;37(45):e11878
Advanced materials (Deerfield Beach, Fla.) 2025 Nov;37(45):e11878
Inhibition of spreading depolarizations by targeting GABA(A) receptors and voltage-gated sodium channels improves neurological deficits in rats with traumatic brain injury.
Yan R, Liu Q, Zhang D, Li K, Li Y, Nie Y, Zhang Y, Li P, Mao S, Li H
British journal of pharmacology 2025 Nov;182(21):5247-5268
British journal of pharmacology 2025 Nov;182(21):5247-5268
Exercise-induced weight loss modulates brain iron and omega-3 fatty acid metabolism in middle-aged obese rats.
Lin WL, Chang CC, Chen SH, Faradina A, Chiu WC, Huang SY, Tung TH, Tseng SH, Skalny AV, Tinkov AA, Aschner M, Chang JS
Nutrition (Burbank, Los Angeles County, Calif.) 2025 Nov;139:112872
Nutrition (Burbank, Los Angeles County, Calif.) 2025 Nov;139:112872
Migration of CD8 + TSCM cells into intestine via PPBP-CXCR2 axis increases host stress susceptibility by inhibiting gut microbiome-derived homovanillic acid.
Zhang Y, Ju M, Chen S, Yang W, Cai Y, Yu X, Chen G, Shen Z, Bai Y, Ren H, Li Y, Shen L, Li J, Shi P, Yuan Y, Han B, Yao H
Nature communications 2025 Nov 19;16(1):10165
Nature communications 2025 Nov 19;16(1):10165
Design of anti-depressant phosphodiester amino acidic Keap1-Nrf2 protein-protein interaction inhibitors.
Sun Y, Wang J, Ding W, Qin Q, Wang R, Yu R, Yan J, Hou R, Liu G, Cai X, Qu Z, Zhang W, Yu J, Xing C, Zhuang C
Redox biology 2025 May;82:103620
Redox biology 2025 May;82:103620
Identification of preventive biomarkers associated with circadian rhythms in traumatic brain injury-mediated depression: Expression of SERPINE1 protein and bioinformatics analysis.
Cai Y, Huang G, Ren M, Zhang X, Yan T, Zhu L
International journal of biological macromolecules 2025 May;310(Pt 1):143229
International journal of biological macromolecules 2025 May;310(Pt 1):143229
Astragalin alleviates lipopolysaccharide-induced depressive-like behavior in mice by preserving blood-brain barrier integrity and suppressing neuroinflammation.
Cao MM, Guo Z, Wang J, Ma HY, Qin XY, Hu Y, Lan R
Free radical biology & medicine 2025 May;232:340-352
Free radical biology & medicine 2025 May;232:340-352
Semaglutide and High-Intensity Interval Exercise Attenuate Cognitive Impairment in Type 2 Diabetic Mice via BDNF Modulation.
Lai S, Kang Z, Sun J, Wang Z, Xu Y, Xing S, Feng M, Wang Y, Liu H
Brain sciences 2025 May 1;15(5)
Brain sciences 2025 May 1;15(5)
Bone-brain communication mediates the amelioration of Polgonatum cyrtonema Hua polysaccharide on fatigue in chronic sleep-deprived mice.
Zhang T, Li XY, Kuang DD, Pan LH, Li QM, Luo JP, Zha XQ
International journal of biological macromolecules 2025 Mar;296:139706
International journal of biological macromolecules 2025 Mar;296:139706
Allium Macrostemon Bge. Attenuates the Cognitive Decline of Aging Mice by Enhancing BDNF/TrkB Pathway.
Sheng R, Zhao M, Pu K, Zhou Y, Zeng L, Chen Y, Wang P, Liu X, Xu S
Food science & nutrition 2025 Mar;13(3):e70010
Food science & nutrition 2025 Mar;13(3):e70010
Muscone enhances synaptic function in vascular dementia through activating BDNF-TrkB-NP2 signaling pathway.
Huang P, Sun H, Chen Y, Li J, Peng Y, Ge C, Zhu K, Zhou X, Chang D, Wang N
International immunopharmacology 2025 Mar 6;149:114232
International immunopharmacology 2025 Mar 6;149:114232
Resolvin D1 accelerates resolution of neuroinflammation by inhibiting microglia activation through the BDNF/TrkB signaling pathway.
Bo C, Liu X, Liu Y, Xu L, Huang Q
European journal of medical research 2025 Mar 20;30(1):189
European journal of medical research 2025 Mar 20;30(1):189
Senegenin regulates the mechanism of insomnia through the Keap1/Nrf2/PINK1/Parkin pathway mediated by GAD67.
Jia H, Chen X, Liang Z, Liang R, Wu J, Hu Y, Cui W, Zhang X
Journal of sleep research 2025 Jun;34(3):e14354
Journal of sleep research 2025 Jun;34(3):e14354
TSPO activation ameliorates maternal immune activation induced PV interneuron deficits via BDNF/TrkB signaling.
Mao MJ, Yu HL, Liu QZ, Wen YZ, Jiang M, Yuan HM, Zeng HB, Zhang LD, Feng SW
Psychopharmacology 2025 Jun;242(6):1303-1319
Psychopharmacology 2025 Jun;242(6):1303-1319
GPR43 regulates mitochondrial apoptosis through the cyclophilin D pathway in Alzheimer's disease.
Wang X, Wu S, Deng Z, Yan M, Wang D, Yang M, Zhong F, Song J, Chen L, Chen Y, Tian Q, Yu W, Lü Y
Molecular medicine (Cambridge, Mass.) 2025 Jun 4;31(1):219
Molecular medicine (Cambridge, Mass.) 2025 Jun 4;31(1):219
Thioredoxin-1 Downregulation in the SNpc Exacerbates the Cognitive Impairment Induced by MPTP.
Zhang X, Yan F, He XJ, Chen Y, Gu R, Dong X, Wei Y, Bai L, Bai J
Antioxidants & redox signaling 2025 Jul;43(1-3):138-150
Antioxidants & redox signaling 2025 Jul;43(1-3):138-150
Kai-Xin-San ameliorates fluoxetine-resistant depressive-like behaviors by modulating tryptophan-kynurenine metabolic homeostasis in a rodent model.
Yao L, Jing R, Wang C, Wang Y, Li X, Wu X, Wang Y, Liu L, Mu L, Liu P, Hu Y
Journal of ethnopharmacology 2025 Jul 24;351:120011
Journal of ethnopharmacology 2025 Jul 24;351:120011
Hydrogel system with growth cone-targeted hydroxyapatite nanorods: Regulating calcium signals for peripheral nerve injury repair.
Li Z, Tang X, Yang H, Lu L, Zhang J, Liu Y
Acta biomaterialia 2025 Jul 1;201:171-186
Acta biomaterialia 2025 Jul 1;201:171-186
Magnolol acts as a neurorestorative agent in an A(β1‑42)‑induced mouse model of Alzheimer's disease.
Yu Q, Shi Y, Wu Y, Liu R, Zhang H, Wu L, Ding M
Experimental and therapeutic medicine 2025 Jan;29(1):12
Experimental and therapeutic medicine 2025 Jan;29(1):12
Liangxue Tongyu Prescription exerts neuroprotection by regulating the microbiota-gut-brain axis of rats with acute intracerebral hemorrhage.
Sun Y, Zhou D, Liu A, Zhou Y, Zhao Y, Yuan Y, Guo W, Li J
Brain research bulletin 2025 Jan;220:111186
Brain research bulletin 2025 Jan;220:111186
Pink1/Parkin signaling mediates pineal mitochondrial autophagy dysfunction and its biological role in a comorbid rat model of depression and insomnia.
Li Z, Shu Y, Liu D, Xie S, Xian L, Luo J, Huang X, Jiang H
Brain research bulletin 2025 Jan;220:111141
Brain research bulletin 2025 Jan;220:111141
TREM2 alleviates long-term cognitive dysfunction after subarachnoid hemorrhage in mice by attenuating hippocampal neuroinflammation via PI3K/Akt signaling pathway.
Tang S, Xing W, Yan J, Wang L, Li Z, Wang Y, Gu N, Sun X
Brain research 2025 Jan 1;1846:149235
Brain research 2025 Jan 1;1846:149235
Xiao-Chai-Hu-Tang Ameliorates Depressive Symptoms via Modulating Neuro-Endocrine Network in Chronic Unpredictable Mild Stress-Induced Mice.
Feng Y, Wang W, Zhang Y, Feng Y, Zhao Y, Zhang Z, Wang Y
CNS neuroscience & therapeutics 2025 Feb;31(2):e70290
CNS neuroscience & therapeutics 2025 Feb;31(2):e70290
Jiawei Kongsheng Zhenzhong Pill (JKZP) Alleviates Chronic Cerebral Hypoperfusion-Induced Hippocampal Synaptic Damage via S100A10/tPA/BDNF Pathway.
Wu Q, Zhou Y, Ou C, Gao Z, Wu X, Zhao Y, Wang Y, Wu Z, Yu H
Brain and behavior 2025 Feb;15(2):e70328
Brain and behavior 2025 Feb;15(2):e70328
Syringa oblata Lindl extract alleviated corticosterone-induced depression via the cAMP/PKA-CREB-BDNF pathway.
A RH, Gong Q, Tuo YJ, Zhai ST, He BL, Zou EG, Wang ML, Huang TY, Zha CL, He MZ, Zhong GY, Feng YL, Li J
Journal of ethnopharmacology 2025 Feb 11;341:119274
Journal of ethnopharmacology 2025 Feb 11;341:119274
Exploring the effect and mechanism of action of Jinlida granules (JLD) in the treatment of diabetes-associated cognitive impairment based on network pharmacology with experimental validation.
Gu H, Zhang Y, Sun J, Liu L, Liu Z
Annals of medicine 2025 Dec;57(1):2445181
Annals of medicine 2025 Dec;57(1):2445181
Characterizing stroke-related cellular changes in the surviving neurons of mouse ischemic stroke.
Ikegami T, Sasaki T, Shimbo T, Kitayama T, Yamamoto Y, Ouchi Y, Yamazaki S, Sugiyama S, Nishiyama K, Gon Y, Okazaki S, Todo K, Matsumura S, Tamai K, Mochizuki H
Neurochemistry international 2025 Dec;191:106086
Neurochemistry international 2025 Dec;191:106086
Neuromodulatory Effects of Arecoline on Anxiety-like Behavior in Mice Exposed to Chronic Unpredictable Mild Stress.
Zhang X, Wang D, Cui J, Fan B, Wang F, Lu C
International journal of molecular sciences 2025 Dec 29;27(1)
International journal of molecular sciences 2025 Dec 29;27(1)
Analgesic Mechanism of Emodin in Neuropathic Pain Through Inhibiting P2X4 Purinoceptor Signaling.
Chen P, Gong Q, Wang H, Wang C, Wang W, Wu J, Wu Z, Wang L
Molecular neurobiology 2025 Aug;62(8):10210-10227
Molecular neurobiology 2025 Aug;62(8):10210-10227
Different Fasting Methods Combined With Running Exercise Regulate Glucose Metabolism via AMPK/SIRT1/BDNF Pathway in Mice.
Wang X, Shi J, Li Y, Zhou L, Xu L, Wang J, Liu C, Liang B
Comprehensive Physiology 2025 Aug;15(4):e70031
Comprehensive Physiology 2025 Aug;15(4):e70031
COG1410 Alleviated Chronic Sleep Deprivation-Induced Memory Loss by Regulating Microglial Phagocytosis and Inhibiting Hippocampal Inflammation.
Wu P, Fu C, Chen M, Wu F, He W, Luo Q, Wang H, Li Y
ACS chemical neuroscience 2025 Aug 6;16(15):2921-2934
ACS chemical neuroscience 2025 Aug 6;16(15):2921-2934
Low-intensity millimeter waves ameliorate cognitive impairment induced by chronic REM sleep deprivation in rats by regulating CaMKII-CREB-BDNF pathway.
Li YZ, Zhou L, Cheng J, Williams JP, Wang PC, An JX
Neuroscience 2025 Aug 16;581:83-94
Neuroscience 2025 Aug 16;581:83-94
Alpha‑Asarone Ameliorates Neuronal Injury After Ischemic Stroke and Hemorrhagic Transformation by Attenuating Blood-Brain Barrier Destruction, Promoting Neurogenesis, and Inhibiting Neuroinflammation.
Luo L, Hu Q, Yan R, Gao X, Zhang D, Yan Y, Liu Q, Mao S
Molecular neurobiology 2025 Apr;62(4):5252-5272
Molecular neurobiology 2025 Apr;62(4):5252-5272
Understanding the Antidepressant Mechanisms of Acupuncture: Targeting Hippocampal Neuroinflammation, Oxidative Stress, Neuroplasticity, and Apoptosis in CUMS Rats.
Li J, Wu X, Yan S, Shen J, Tong T, Aslam MS, Zeng J, Chen Y, Chen W, Li M, You Z, Gong K, Yang J, Zhu M, Meng X
Molecular neurobiology 2025 Apr;62(4):4221-4236
Molecular neurobiology 2025 Apr;62(4):4221-4236
Acoustic Enrichment Prevents Early Life Stress-Induced Disruptions in Sound Azimuth Processing.
An P, Fang Y, Cheng Y, Liu H, Yang W, Shan Y, de Villers-Sidani E, Zhang G, Zhou X
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Apr 30;45(18)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Apr 30;45(18)
Adult Neurogenesis Is Regulated by the Endocannabinoid and Kisspeptin Systems.
Marino M, Di Pietro P, D'Auria R, Lombardi M, Pastorino GMG, Troisi J, Operto FF, Carrizzo A, Vecchione C, Viggiano A, Meccariello R, Santoro A
International journal of molecular sciences 2025 Apr 23;26(9)
International journal of molecular sciences 2025 Apr 23;26(9)
High urea promotes mitochondrial fission and functional impairments in astrocytes inducing anxiety-like behavior in chronic kidney disease mice.
Zhao X, Zhang S, Wu M, Zhang B, Wan G, Zhang M, Li J, Fei Z, Zhu G, Jiang S, Xiao M, Liu W, Zhao Z, Huang B, Ran J
Metabolic brain disease 2025 Apr 17;40(5):186
Metabolic brain disease 2025 Apr 17;40(5):186
Effect of histone demethylase KDM5B on long-term cognitive impairment in neonatal rats induced by sevoflurane.
Wang Y, Chen Y, Zhang M, Yuan C, Zhang Y, Liu X, Zhang Y, Liang X
Frontiers in molecular neuroscience 2024;17:1459358
Frontiers in molecular neuroscience 2024;17:1459358
Enriched oxygen improves age-related cognitive impairment through enhancing autophagy.
Wang S, Chen B, Yuan M, Liu S, Fan H, Yang X, Zou Q, Pu Y, Cai Z
Frontiers in aging neuroscience 2024;16:1340117
Frontiers in aging neuroscience 2024;16:1340117
Asiaticoside improves depressive-like behavior in mice with chronic unpredictable mild stress through modulation of the gut microbiota.
Ren Q, He C, Sun Y, Gao X, Zhou Y, Qin T, Zhang Z, Wang X, Wang J, Wei S, Wang F
Frontiers in pharmacology 2024;15:1461873
Frontiers in pharmacology 2024;15:1461873
Anti-neuroinflammatory effect of hydroxytyrosol: a potential strategy for anti-depressant development.
Li S, Shao H, Sun T, Guo X, Zhang X, Zeng Q, Fang S, Liu X, Wang F, Liu F, Ling P
Frontiers in pharmacology 2024;15:1366683
Frontiers in pharmacology 2024;15:1366683
Nicotine inhalant via E-cigarette facilitates sensorimotor function recovery by upregulating neuronal BDNF-TrkB signalling in traumatic brain injury.
Wang D, Li X, Li W, Duong T, Wang H, Kleschevnikova N, Patel HH, Breen E, Powell S, Wang S, Head BP
British journal of pharmacology 2024 Sep;181(17):3082-3097
British journal of pharmacology 2024 Sep;181(17):3082-3097
NMC-4 Ameliorates Depression-Like Behavior and Neuroinflammation Caused by Chronic Unpredictable Mild Stress.
Chen Y, Gu H, Ye D, Li Y, Chen Y, Qiao H, Huang Y, Tao R, Yu S, Zhang J, Fei W, Wang L
Chemical biology & drug design 2024 Sep;104(3):e14626
Chemical biology & drug design 2024 Sep;104(3):e14626
Neuroinflammation inhibition and neuroprotective effects of purpurin, a potential anti-AD compound, screened via network proximity and gene enrichment analyses.
Zhao J, Guo P, Fang J, Wang C, Yan C, Bai Y, Wang Z, Du G, Liu A
Phytotherapy research : PTR 2024 Nov;38(11):5474-5489
Phytotherapy research : PTR 2024 Nov;38(11):5474-5489
GOS enhances BDNF-mediated mammary gland development in pubertal mice via the gut-brain axis.
Ge Y, Cao Y, Zhang J, Li F, Wang J, Sun M, Liu Y, Long X, Guo W, Liu J, Fu S
NPJ biofilms and microbiomes 2024 Nov 19;10(1):130
NPJ biofilms and microbiomes 2024 Nov 19;10(1):130
MiR-204 regulates autophagy and cell viability by targeting BDNF and inhibiting the NTRK2-dependent PI3K/Akt/mTOR pathway in a human granulosa cell line exposed to bisphenol A.
Li C, Cui Z, Liu Z, Fan H, Lan Y, Luo J, Ruan F, Huang Y, Chu K, Wu Y, Xia D, Zhou J
Ecotoxicology and environmental safety 2024 Nov 15;287:117304
Ecotoxicology and environmental safety 2024 Nov 15;287:117304
Effects on Synaptic Plasticity Markers in Fetal Mice and HT22 Neurons upon F-53B Exposure: The Role of PKA Cytoplasmic Retention.
Li SP, Zeng HX, Qin SJ, Li QQ, Wu LY, Wu QZ, Lin LZ, Dong GH, Zeng XW
Environment & health (Washington, D.C.) 2024 Nov 15;2(11):776-785
Environment & health (Washington, D.C.) 2024 Nov 15;2(11):776-785
Treatment of Parkinson's disease model with human umbilical cord mesenchymal stem cell-derived exosomes loaded with BDNF.
Wang CC, Hu XM, Long YF, Huang HR, He Y, Xu ZR, Qi ZQ
Life sciences 2024 Nov 1;356:123014
Life sciences 2024 Nov 1;356:123014
Exploring miR-21 as a key regulator in two distinct approaches of bone marrow stromal cells differentiation into Schwann-like cells.
Liu YM, Wang HY, Wei CH, Li JP, Wang Y, Ma WZ, Jia H
Synapse (New York, N.Y.) 2024 May;78(3):e22293
Synapse (New York, N.Y.) 2024 May;78(3):e22293
Particulate matter (PM(10)) exacerbates on MK-801-induced schizophrenia-like behaviors through the inhibition of ERK-CREB-BDNF signaling pathway.
Choi SH, Bae HJ, Kim SY, Mony TJ, Kim HJ, Cho YE, Choi YY, An JY, Cho SY, Kim DH, Park SJ
Ecotoxicology and environmental safety 2024 May;276:116294
Ecotoxicology and environmental safety 2024 May;276:116294
Mecp2 Deficiency in Peripheral Sensory Neuron Improves Cognitive Function by Enhancing Hippocampal Dendritic Spine Densities in Mice.
Feng Y, Wang J, Liu J, Zhou Y, Jiang Y, Zhou W, Wu F, Liu X, Luo L
Cells 2024 Jun 6;13(11)
Cells 2024 Jun 6;13(11)
Deciphering the antidepressant effects of Rosa damascena essential oil mediated through the serotonergic synapse signaling pathway.
Xia N, Wang J, Guo Q, Duan J, Wang X, Zhou P, Li J, Tang T, Li T, Li H, Wu Z, Yang M, Sun J, Guo D, Chang X, Zhang X
Journal of ethnopharmacology 2024 Jun 28;328:118007
Journal of ethnopharmacology 2024 Jun 28;328:118007
Human iPSC-derived endothelial cells promote CNS remyelination via BDNF and mTORC1 pathway.
Ma D, Zhang H, Yin L, Xu H, Wu L, Shaji R, Rezai F, Mulla A, Kaur S, Tan S, Kysela B, Wang Y, Chen Z, Zhao C, Gu Y
Glia 2024 Jan;72(1):133-155
Glia 2024 Jan;72(1):133-155
Electroacupuncture ameliorates chronic unpredictable mild stress-induced depression-like behavior and cognitive impairment through suppressing oxidative stress and neuroinflammation in rats.
Tong T, Hao C, Shen J, Liu S, Yan S, Aslam MS, Chen Y, Chen W, Li J, Li Y, Zeng J, Li M, You Z, Gulizhaerkezi T, Wei S, Zhu A, Meng X
Brain research bulletin 2024 Jan;206:110838
Brain research bulletin 2024 Jan;206:110838
Knockdown of Smox protects the integrity of the blood-brain barrier through antioxidant effect and Nrf2 pathway activation in stroke.
Wang G, Li Z, Lin P, Zhang H, Wang Y, Zhang T, Wang H, Li H, Lin L, Zhao Y, Jia L, Chen Y, Ji H, Zhao W, Fu Z, Zhong Z
International immunopharmacology 2024 Jan 5;126:111183
International immunopharmacology 2024 Jan 5;126:111183
The role of NF-κB signaling pathway in reactive astrocytes among neurodegeneration after methamphetamine exposure by integrated bioinformatics.
Li K, Ling H, Wang X, Xie Q, Gu C, Luo W, Qiu P
Progress in neuro-psychopharmacology & biological psychiatry 2024 Feb 8;129:110909
Progress in neuro-psychopharmacology & biological psychiatry 2024 Feb 8;129:110909
Tong-Qiao-Huo-Xue Decoction promotes synaptic remodeling via cAMP/PKA/CREB pathway in vascular dementia rats.
Li J, Ye H, Xu F, Yang Y, Ge C, Yao M, Huang P, Wang L, Wang N, Zhou X, Chang D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156166
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156166
Analysis of microisolated frontal cortex excitatory layer III and V pyramidal neurons reveals a neurodegenerative phenotype in individuals with Down syndrome.
Alldred MJ, Pidikiti H, Ibrahim KW, Lee SH, Heguy A, Hoffman GE, Roussos P, Wisniewski T, Wegiel J, Stutzmann GE, Mufson EJ, Ginsberg SD
Acta neuropathologica 2024 Aug 6;148(1):16
Acta neuropathologica 2024 Aug 6;148(1):16
Comparison of CUMS at different pregnancy stages, maternal separation, and their effects on offspring in postpartum depression mouse models.
Fei F, Chen Z, Tao Y, Jiang X, Xu X, Ma Y, Feng P, Wang P
Heliyon 2024 Aug 15;10(15):e35363
Heliyon 2024 Aug 15;10(15):e35363
5Z-7-Oxozaenol attenuates cuprizone-induced demyelination in mice through microglia polarization regulation.
Chen S, Liu S, Huang Y, Huang S, Zhang W, Xie H, Lu L
Brain and behavior 2024 Apr;14(4):e3487
Brain and behavior 2024 Apr;14(4):e3487
Dietary High-Fat Promotes Cognitive Impairment by Suppressing Mitophagy.
Wen J, Wang Y, Wang C, Yuan M, Chen F, Zou Q, Cai Z, Zhao B
Oxidative medicine and cellular longevity 2023;2023:4822767
Oxidative medicine and cellular longevity 2023;2023:4822767
Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis.
Meng P, Zhang X, Li D, Yang H, Lin X, Zhao H, Li P, Wang Y, Wang X, Ge J
Neural plasticity 2023;2023:1455634
Neural plasticity 2023;2023:1455634
Integrating Network Pharmacology, Molecular Docking and Pharmacological Evaluation for Exploring the Polyrhachis vicina Rogers in Ameliorating Depression.
He J, Han D, Jia C, Xie J, Zhu F, Wei J, Li D, Wei D, Li Y, Tang L, Wei G, Yan J, Tong Y, Yang L, Tan X
Drug design, development and therapy 2023;17:717-735
Drug design, development and therapy 2023;17:717-735
Bacteroides vulgatus alleviates dextran sodium sulfate-induced colitis and depression-like behaviour by facilitating gut-brain axis balance.
Wu X, Xu J, Li J, Deng M, Shen Z, Nie K, Luo W, Zhang C, Ma K, Chen X, Wang X
Frontiers in microbiology 2023;14:1287271
Frontiers in microbiology 2023;14:1287271
Dopamine receptor 1 on CaMKII-positive neurons within claustrum mediates adolescent cocaine exposure-induced anxiety-like behaviors and electro-acupuncture therapy.
Chen L, Liu Z, Zhao Z, Du D, Pan W, Wei X, Nie J, Ge F, Ding J, Fan Y, Kim HY, Guan X
Theranostics 2023;13(10):3149-3164
Theranostics 2023;13(10):3149-3164
Body Weight Support Treadmill Training Combined With Sciatic Nerve Electrical Stimulation Ameliorating Motor Function by Enhancing PI3K/Akt Proteins Expression via BDNF/TrkB Signaling Pathway in Rats with Spinal Cord Injury.
Xu Q, Li Z, Su J, Hu M, Yin Q, Chen S, Song J, Chen H
World neurosurgery 2023 Oct;178:e239-e253
World neurosurgery 2023 Oct;178:e239-e253
Dexmedetomidine alleviates propofol-induced neural injury in developing rats.
Xiao W, Chen S, Chen J, Huang J
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2023 Nov;83(7):631-640
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2023 Nov;83(7):631-640
The Combination of Citicoline and Nicotinamide Mononucleotide Induces Neurite Outgrowth and Mitigates Vascular Cognitive Impairment via SIRT1/CREB Pathway.
Zhao N, Zhu X, Xie L, Guan X, Tang L, Jiang G, Pang T
Cellular and molecular neurobiology 2023 Nov;43(8):4261-4277
Cellular and molecular neurobiology 2023 Nov;43(8):4261-4277
Antidepressant effects of 70% ethanolic extract of Lonicerae japonicae flos and it contained chlorogenic acid via upregulation of BDNF-TrkB pathway in the hippocampus of mice.
Qin L, Wang J, Wu X, Song L, Zhang Y, Gong M, Wang Y, Li B
Brain research bulletin 2023 Nov;204:110796
Brain research bulletin 2023 Nov;204:110796
Manganese-enhanced magnetic resonance assessment of changes in hippocampal neural function after the treatment of radiation-induced brain injury with bone marrow mesenchymal stem cells.
Liu Z, Xu K, Pan S, Zhang N, Wang D, Chen Y, Zhao Y, Wang S, Li J, Tong X
Brain research bulletin 2023 Nov;204:110795
Brain research bulletin 2023 Nov;204:110795
The role of EndophilinA1 in chronic unpredicted mild stress-induced depression model mice.
Liu M, Ling Y, Zhang Y, Liu L, Qiu Y, Liu Y, Yin Y
International immunopharmacology 2023 Nov;124(Pt B):111023
International immunopharmacology 2023 Nov;124(Pt B):111023
The total alkaloids of Sophora alopecuroides L. improve depression-like behavior in mice via BDNF-mediated AKT/mTOR signaling pathway.
Li J, Zhang M, Pei Y, Yang Q, Zheng L, Wang G, Sun Y, Yang W, Liu L
Journal of ethnopharmacology 2023 Nov 15;316:116723
Journal of ethnopharmacology 2023 Nov 15;316:116723
NMN Alleviates NP-Induced Learning and Memory Impairment Through SIRT1 Pathway in PC-12 Cell.
Li Z, Liu H, Han W, Zhu S, Liu C
Molecular neurobiology 2023 May;60(5):2871-2883
Molecular neurobiology 2023 May;60(5):2871-2883
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway.
Sun X, Huang LY, Pan HX, Li LJ, Wang L, Pei GQ, Wang Y, Zhang Q, Cheng HX, He CQ, Wei Q
Neural regeneration research 2023 May;18(5):1067-1075
Neural regeneration research 2023 May;18(5):1067-1075
Prenatal alcohol exposure enhanced alcohol preference and susceptibility to PTSD in a sex-dependent manner through the synaptic HCN1 channel.
Yao H, Wang C, Xia Z
Journal of affective disorders 2023 Mar 1;324:143-152
Journal of affective disorders 2023 Mar 1;324:143-152
A whole transcriptome profiling analysis for antidepressant mechanism of Xiaoyaosan mediated synapse loss via BDNF/trkB/PI3K signal axis in CUMS rats.
Meng P, Zhang X, Liu TT, Liu J, Luo Y, Xie MX, Yang H, Fang R, Guo DW, Zhong ZY, Wang YH, Ge JW
BMC complementary medicine and therapies 2023 Jun 15;23(1):198
BMC complementary medicine and therapies 2023 Jun 15;23(1):198
Inhibition of TREM-1 ameliorates Lipopolysaccharide-induced depressive-like behaviors by alleviating neuroinflammation in the PFC via PI3K/Akt signaling pathway.
Fu A, Qiao F, Feng H, Luo Q
Behavioural brain research 2023 Jul 9;449:114464
Behavioural brain research 2023 Jul 9;449:114464
Modulatory effect of n-3 polyunsaturated fatty acids on depressive-like behaviors in rats with chronic sleep deprivation: potential involvement of melatonin receptor pathway and brain lipidome.
Chang CH, Wu HC, Hsieh YR, Lai WD, Tung TH, Huang JJ, Kao WY, Huang SY
Food & function 2023 Jul 3;14(13):5977-5993
Food & function 2023 Jul 3;14(13):5977-5993
Omega-3 Polyunsaturated Fatty Acid Eicosapentaenoic Acid or Docosahexaenoic Acid Improved Ageing-Associated Cognitive Decline by Regulating Glial Polarization.
Xia J, Yang L, Huang C, Deng S, Yang Z, Zhang Y, Zhang C, Song C
Marine drugs 2023 Jul 10;21(7)
Marine drugs 2023 Jul 10;21(7)
BDNF guides neural stem cell-derived axons to ventral interneurons and motor neurons after spinal cord injury.
Li Y, Tran A, Graham L, Brock J, Tuszynski MH, Lu P
Experimental neurology 2023 Jan;359:114259
Experimental neurology 2023 Jan;359:114259
Antidepression of Xingpijieyu formula targets gut microbiota derived from depressive disorder.
Li Y, Yang L, Li J, Gao W, Zhao Z, Dong K, Duan W, Dai B, Guo R
CNS neuroscience & therapeutics 2023 Feb;29(2):669-681
CNS neuroscience & therapeutics 2023 Feb;29(2):669-681
Neural stem cell-derived exosome as a nano-sized carrier for BDNF delivery to a rat model of ischemic stroke.
Zhu ZH, Jia F, Ahmed W, Zhang GL, Wang H, Lin CQ, Chen WH, Chen LK
Neural regeneration research 2023 Feb;18(2):404-409
Neural regeneration research 2023 Feb;18(2):404-409
Tunicamycin induces depression-like behaviors in male rats, accompanied by initiated chaperon-mediated autophagy and decreased synaptic protein expression in the hippocampus.
Yuan G, Xiao L, Xie Y, Si L, Xu H, Xu W, Wang G
Neuroscience letters 2023 Feb 28;798:137058
Neuroscience letters 2023 Feb 28;798:137058
Matrine alleviates depressive-like behaviors via modulating microbiota-gut-brain axis in CUMS-induced mice.
Zhang M, Li A, Yang Q, Li J, Zheng L, Wang G, Sun Y, Huang Y, Zhang M, Song Z, Liu L
Journal of translational medicine 2023 Feb 24;21(1):145
Journal of translational medicine 2023 Feb 24;21(1):145
MICROGLIA AND INFILTRATING T-CELLS ADOPT LONG-TERM, AGE-SPECIFIC, TRANSCRIPTIONAL CHANGES AFTER TRAUMATIC BRAIN INJURY IN MICE.
Chen Z, Islam MBAR, Ford KP, Zhao G, Chen SY, Wang Y, Davis BT 4th, Mentis AA, Schwulst SJ
Shock (Augusta, Ga.) 2023 Feb 1;59(2):267-276
Shock (Augusta, Ga.) 2023 Feb 1;59(2):267-276
Metformin Improves Comorbid Depressive Symptoms in Mice with Allergic Rhinitis by Reducing Olfactory Bulb Damage.
Lv H, Gao Z, Wang Y, Chen S, Liu P, Xie Y, Guan M, Cong J, Xu Y
Neurochemical research 2023 Dec;48(12):3639-3651
Neurochemical research 2023 Dec;48(12):3639-3651
TRIM69 suppressed the anoikis resistance and metastasis of gastric cancer through ubiquitin‒proteasome-mediated degradation of PRKCD.
Sun L, Chen Y, Xia L, Wang J, Zhu J, Li J, Wang K, Shen K, Zhang D, Zhang G, Shi T, Chen W
Oncogene 2023 Dec;42(49):3619-3632
Oncogene 2023 Dec;42(49):3619-3632
Lactate Mediates High-Intensity Interval Training-Induced Promotion of Hippocampal Mitochondrial Function through the GPR81-ERK1/2 Pathway.
Shang Q, Bian X, Zhu L, Liu J, Wu M, Lou S
Antioxidants (Basel, Switzerland) 2023 Dec 7;12(12)
Antioxidants (Basel, Switzerland) 2023 Dec 7;12(12)
Synergistic effects of lipopolysaccharide and rotenone on dopamine neuronal damage in rats.
He JY, Li DD, Wen Q, Qin TY, Long H, Zhang SB, Zhang F
CNS neuroscience & therapeutics 2023 Aug;29(8):2281-2291
CNS neuroscience & therapeutics 2023 Aug;29(8):2281-2291
The effects of acupuncture on depression by regulating BDNF-related balance via lateral habenular nucleus BDNF/TrkB/CREB signaling pathway in rats.
Tong T, Chen Y, Hao C, Shen J, Chen W, Cheng W, Yan S, Li J, Li Y, Gulizhaerkezi T, Zeng J, Meng X
Behavioural brain research 2023 Aug 5;451:114509
Behavioural brain research 2023 Aug 5;451:114509
Aripiprazole combined with nerve growth factor improves cognitive function in mice with schizophrenia model.
Lu C, Li S, Kang L, Li Q, Chen H, Lin Y, Zhang H, Tang Z, Bai M, Xiong P
Neuroscience letters 2023 Aug 24;812:137410
Neuroscience letters 2023 Aug 24;812:137410
Aerobic Exercise Facilitates the Nuclear Translocation of SREBP2 by Activating AKT/SEC24D to Contribute Cholesterol Homeostasis for Improving Cognition in APP/PS1 Mice.
Hu Z, Yuan Y, Tong Z, Liao M, Yuan S, Wu W, Tang Y, Wang Y, Tang C, Liu W
International journal of molecular sciences 2023 Aug 16;24(16)
International journal of molecular sciences 2023 Aug 16;24(16)
Benzene, 1,2,4-Trimethoxy-5-(2-Methyl-1-Propen-1-yl) Attenuates D-galactose/AlCl(3)-induced Cognitive Impairment by Inhibiting Inflammation, Apoptosis, and improving Expression of Memory-Related Proteins.
Yang P, Liao C, Hu Q, Zhang J, Yang H, Xian S, Mao S
Neuroscience 2023 Aug 1;524:242-255
Neuroscience 2023 Aug 1;524:242-255
Treatment Combining Focused Ultrasound with Gastrodin Alleviates Memory Deficit and Neuropathology in an Alzheimer's Disease-Like Experimental Mouse Model.
Luo K, Wang Y, Chen WS, Feng X, Liao Y, Chen S, Liu Y, Liao C, Chen M, Ao L
Neural plasticity 2022;2022:5241449
Neural plasticity 2022;2022:5241449
Cinnamic Acid Improved Lipopolysaccharide-Induced Depressive-Like Behaviors by Inhibiting Neuroinflammation and Oxidative Stress in Mice.
Zhuo R, Cheng X, Luo L, Yang L, Zhao Y, Zhou Y, Peng L, Jin X, Cui L, Liu F, Yang L
Pharmacology 2022;107(5-6):281-289
Pharmacology 2022;107(5-6):281-289
Analgesic effect of nobiletin against neuropathic pain induced by the chronic constriction injury of the sciatic nerve in mice.
Zhu C, Tian M, Liu N, Ma L, Lan X, Yang J, Du J, Ma H, Li Y, Zheng P, Yu J, Peng X
Phytotherapy research : PTR 2022 Sep;36(9):3644-3661
Phytotherapy research : PTR 2022 Sep;36(9):3644-3661
Enhanced effect of combining bone marrow mesenchymal stem cells (BMMSCs) and pulsed electromagnetic fields (PEMF) to promote recovery after spinal cord injury in mice.
Huang L, Sun X, Wang L, Pei G, Wang Y, Zhang Q, Liang Z, Wang D, Fu C, He C, Wei Q
MedComm 2022 Sep;3(3):e160
MedComm 2022 Sep;3(3):e160
Antidepressant effect of Jujuboside A on corticosterone-induced depression in mice.
Li H, Li J, Zhang T, Xie X, Gong J
Biochemical and biophysical research communications 2022 Sep 10;620:56-62
Biochemical and biophysical research communications 2022 Sep 10;620:56-62
N-linoleyltyrosine protects neurons against Aβ(1-40)-induced cell toxicity via autophagy involving the CB(2)/AMPK/mTOR/ULK1 pathway.
Zhou Y, Li ZX, Liu YT, Xu ZC, Hu Y, Lv W, Yang ZY, Sheng YM, Liu S
Brain research bulletin 2022 Oct 1;188:203-213
Brain research bulletin 2022 Oct 1;188:203-213
Dietary Salt Disrupts Tricarboxylic Acid Cycle and Induces Tau Hyperphosphorylation and Synapse Dysfunction during Aging.
Yuan M, Wang Y, Wen J, Jing F, Zou Q, Pu Y, Pan T, Cai Z
Aging and disease 2022 Oct 1;13(5):1532-1545
Aging and disease 2022 Oct 1;13(5):1532-1545
Cognitive-exercise dual-task intervention ameliorates cognitive decline in natural aging rats through reducing oxidative stress and enhancing synaptic plasticity.
Li XL, Tao X, Li TC, Zhu ZM, Huang PL, Gong WJ
Experimental gerontology 2022 Nov;169:111981
Experimental gerontology 2022 Nov;169:111981
Sodium butyrate exerts antioxidant stress effects and attenuates Aβ(25-35)-induced cytotoxicity in PC12 cells.
Yuan B, Liu M, Gong Y, Wang Z, Jin X, Xie G, Zhu M, Zhang X, Luo S, Qu Q, Zhu Y, Wang M, Jin Y, Li B, Wang W
Archives of biochemistry and biophysics 2022 Nov 30;731:109448
Archives of biochemistry and biophysics 2022 Nov 30;731:109448
Effect of dendrobium mixture in alleviating diabetic cognitive impairment associated with regulating gut microbiota.
Zheng Y, Zhou X, Wang C, Zhang J, Chang D, Zhuang S, Xu W, Chen Y, Wang X, Nan L, Sun Y, Lin X, Lin W, He C, Dai L, Zhang J, Chen J, Shi H, Huang M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112891
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112891
IL-33 in the basolateral amygdala integrates neuroinflammation into anxiogenic circuits via modulating BDNF expression.
Zhuang X, Zhan B, Jia Y, Li C, Wu N, Zhao M, Chen N, Guo Y, Du Y, Zhang Y, Cao B, Li Y, Zhu F, Guo C, Wang Q, Li Y, Zhang L
Brain, behavior, and immunity 2022 May;102:98-109
Brain, behavior, and immunity 2022 May;102:98-109
Estrogen-related Receptor α (ERRα) Functions in The Hypoxic Injury of Microglial Cells.
Deng CY, Zhu TT, Lian S, Wang JF, Wu R, Zheng JS
Journal of veterinary research 2022 Mar;66(1):131-140
Journal of veterinary research 2022 Mar;66(1):131-140
Involvement of the BDNF-TrkB-KCC2 pathway in neuropathic pain after brachial plexus avulsion.
Zhao S, Wang F, Wang L, Xu Y, Lv L, Duan W, Bai R, Meng Z, Shao X
Brain and behavior 2022 Mar;12(3):e2464
Brain and behavior 2022 Mar;12(3):e2464
Fish oil ameliorates neuropsychiatric behaviors and gut dysbiosis by elevating selected microbiota-derived metabolites and tissue tight junctions in rats under chronic sleep deprivation.
Lai WD, Tung TH, Teng CY, Chang CH, Chen YC, Huang HY, Lee HC, Huang SY
Food & function 2022 Mar 7;13(5):2662-2680
Food & function 2022 Mar 7;13(5):2662-2680
Regulation of the kynurenine/serotonin pathway by berberine and the underlying effect in the hippocampus of the chronic unpredictable mild stress mice.
Wang Q, Sun YN, Zou CM, Zhang TL, Li Z, Liu M, Shi BY, Shi SS, Yu CY, Wei TM
Behavioural brain research 2022 Mar 26;422:113764
Behavioural brain research 2022 Mar 26;422:113764
Oral squamous cell carcinoma-released brain-derived neurotrophic factor contributes to oral cancer pain by peripheral tropomyosin receptor kinase B activation.
Grayson M, Arris D, Wu P, Merlo J, Ibrahim T, Fang-Mei C, Valenzuela V, Ganatra S, Ruparel S
Pain 2022 Mar 1;163(3):496-507
Pain 2022 Mar 1;163(3):496-507
Multiple Mild Stimulations Reduce Membrane Distribution of CX3CR1 Promoted by Annexin a1 in Microglia to Attenuate Excessive Dendritic Spine Pruning and Cognitive Deficits Caused by a Transient Ischemic Attack in Mice.
Zheng L, Wang Y, Shao B, Zhou H, Li X, Zhang C, Sun N, Shi J
Neuroscience bulletin 2022 Jul;38(7):753-768
Neuroscience bulletin 2022 Jul;38(7):753-768
Reactive Oxygen Species Scavenging Functional Hydrogel Delivers Procyanidins for the Treatment of Traumatic Brain Injury in Mice.
Huang X, Ye Y, Zhang J, Zhang X, Ma H, Zhang Y, Fu X, Tang J, Jiang N, Han Y, Liu H, Chen H
ACS applied materials & interfaces 2022 Jul 27;14(29):33756-33767
ACS applied materials & interfaces 2022 Jul 27;14(29):33756-33767
Low-dose S-ketamine exerts antidepressant-like effects via enhanced hippocampal synaptic plasticity in postpartum depression rats.
Ren Z, Wang M, Aldhabi M, Zhang R, Liu Y, Liu S, Tang R, Chen Z
Neurobiology of stress 2022 Jan;16:100422
Neurobiology of stress 2022 Jan;16:100422
Injectable hyaluronic acid hydrogel loaded with BMSC and NGF for traumatic brain injury treatment.
Wang L, Zhang D, Ren Y, Guo S, Li J, Ma S, Yao M, Guan F
Materials today. Bio 2022 Jan;13:100201
Materials today. Bio 2022 Jan;13:100201
Bupivacaine reduces GlyT1 expression by potentiating the p-AMPKα/BDNF signalling pathway in spinal astrocytes of rats.
Lu K, Zhao L, Zhang Y, Yang F, Zhang H, Wang J, Li B, Ji G, Yu J, Ma H
Scientific reports 2022 Jan 26;12(1):1378
Scientific reports 2022 Jan 26;12(1):1378
Inhibition of Geranylgeranylacetone on cholecystokinin-B receptor, BDNF and dopamine D1 receptor induced by morphine.
Guo N, Zhang L, Fan W, Bai L, Zhang X, Shi Z, Bai J
Biochemical and biophysical research communications 2022 Jan 15;588:23-28
Biochemical and biophysical research communications 2022 Jan 15;588:23-28
Preparation, Characterization, Evaluation of Neuroprotective Effect, and Related Mechanisms of Phosphatidylserine Emulsion in 5- and 12-Week Old Mice.
Liu B, Zhang N, Yang J, Sun W, Zhang R, Zheng X, Wang Z, Siebert HC, Han J
Journal of agricultural and food chemistry 2022 Feb 16;70(6):1852-1864
Journal of agricultural and food chemistry 2022 Feb 16;70(6):1852-1864
Involvement of the gut-brain axis in vascular depression via tryptophan metabolism: A benefit of short chain fatty acids.
Xiao W, Li J, Gao X, Yang H, Su J, Weng R, Gao Y, Ni W, Gu Y
Experimental neurology 2022 Dec;358:114225
Experimental neurology 2022 Dec;358:114225
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.
Yan J, Zhang Y, Wang L, Li Z, Tang S, Wang Y, Gu N, Sun X, Li L
Journal of neuroinflammation 2022 Dec 3;19(1):289
Journal of neuroinflammation 2022 Dec 3;19(1):289
Exposure to dibutyl phthalate adsorbed to multi-walled carbon nanotubes causes neurotoxicity in mice by inducing the release of BDNF.
Zhou T, He S, Ye X, Wei Z, Wan J, Zhang H, Ding S
The Science of the total environment 2022 Dec 15;852:158319
The Science of the total environment 2022 Dec 15;852:158319
Necrostatin-1 Against Sevoflurane-Induced Cognitive Dysfunction Involves Activation of BDNF/TrkB Pathway and Inhibition of Necroptosis in Aged Rats.
Yin C, Zhang Q, Zhao J, Li Y, Yu J, Li W, Wang Q
Neurochemical research 2022 Apr;47(4):1060-1072
Neurochemical research 2022 Apr;47(4):1060-1072
Maternal stress programs a demasculinization of glutamatergic transmission in stress-related brain regions of aged rats.
Verhaeghe R, Gao V, Morley-Fletcher S, Bouwalerh H, Van Camp G, Cisani F, Nicoletti F, Maccari S
GeroScience 2022 Apr;44(2):1047-1069
GeroScience 2022 Apr;44(2):1047-1069
Prevotella histicola Mitigated Estrogen Deficiency-Induced Depression via Gut Microbiota-Dependent Modulation of Inflammation in Ovariectomized Mice.
Huang F, Liu X, Xu S, Hu S, Wang S, Shi D, Wang K, Wang Z, Lin Q, Li S, Zhao S, Jin K, Wang C, Chen L, Wang F
Frontiers in nutrition 2021;8:805465
Frontiers in nutrition 2021;8:805465
Curcumin Relieves Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior through the PGC-1α/FNDC5/BDNF Pathway.
Wu Y, Sun F, Guo Y, Zhang Y, Li L, Dang R, Jiang P
Behavioural neurology 2021;2021:2630445
Behavioural neurology 2021;2021:2630445
Edaravone Alleviated Propofol-Induced Neurotoxicity in Developing Hippocampus by mBDNF/TrkB/PI3K Pathway.
Yang Y, Yi J, Pan M, Hu B, Duan H
Drug design, development and therapy 2021;15:1409-1422
Drug design, development and therapy 2021;15:1409-1422
Network Pharmacology-Based and Experimental Identification of the Effects of Paeoniflorin on Major Depressive Disorder.
Zhang S, Jiang M, Yan S, Liang M, Wang W, Yuan B, Xu Q
Frontiers in pharmacology 2021;12:793012
Frontiers in pharmacology 2021;12:793012
An Integrative Pharmacology-Based Strategy to Uncover the Mechanism of Xiong-Pi-Fang in Treating Coronary Heart Disease with Depression.
Zhang L, Zhang Y, Zhu M, Pei L, Deng F, Chen J, Zhang S, Cong Z, Du W, Xiao X
Frontiers in pharmacology 2021;12:590602
Frontiers in pharmacology 2021;12:590602
Tetrahydropalmatine Regulates BDNF through TrkB/CAM Interaction to Alleviate the Neurotoxicity Induced by Methamphetamine.
Liu L, Liu M, Zhao W, Zhao YL, Wang Y
ACS chemical neuroscience 2021 Sep 15;12(18):3373-3386
ACS chemical neuroscience 2021 Sep 15;12(18):3373-3386
Merazin Hydrate Produces Rapid Antidepressant Effects Depending on Activating mTOR Signaling by Upregulating Downstream Synaptic Proteins in the Hippocampus.
Lu C, Liu X, Li J, Huang Y, Huang X, Dai G, Wu L
ACS chemical neuroscience 2021 Oct 20;12(20):3939-3946
ACS chemical neuroscience 2021 Oct 20;12(20):3939-3946
The role of SIRT1 in the basolateral amygdala in depression-like behaviors in mice.
Guo H, Deji C, Peng H, Zhang J, Chen Y, Zhang Y, Wang Y
Genes, brain, and behavior 2021 Nov;20(8):e12765
Genes, brain, and behavior 2021 Nov;20(8):e12765
Dopamine receptor 2 downregulation and brain-derived neurotrophic factor upregulation in the paraventricular nucleus are correlated with brown adipose tissue thermogenesis in rats with bilateral substantia nigra lesions.
Zhang Y, Zhou L, Lian H, Zhang Y, Tong S, Wang Z
Journal of chemical neuroanatomy 2021 Nov;117:102016
Journal of chemical neuroanatomy 2021 Nov;117:102016
Chronic ethanol exposure induced depressive-like behavior in male C57BL/6 N mice by downregulating GluA1.
Yao H, Shen H, Yu H, Wang C, Ding R, Lan X, Tash D, Wu X, Wang X, Zhang G
Physiology & behavior 2021 May 15;234:113387
Physiology & behavior 2021 May 15;234:113387
Cardiac glycosaminoglycans and structural alterations during chronic stress-induced depression-like behavior in mice.
Luong H, Singh S, Patil M, Krishnamurthy P
American journal of physiology. Heart and circulatory physiology 2021 May 1;320(5):H2044-H2057
American journal of physiology. Heart and circulatory physiology 2021 May 1;320(5):H2044-H2057
Crocetin ameliorates chronic restraint stress-induced depression-like behaviors in mice by regulating MEK/ERK pathways and gut microbiota.
Lin S, Li Q, Jiang S, Xu Z, Jiang Y, Liu L, Jiang J, Tong Y, Wang P
Journal of ethnopharmacology 2021 Mar 25;268:113608
Journal of ethnopharmacology 2021 Mar 25;268:113608
Neuroprotective effects of bone marrow Sca-1(+) cells against age-related retinal degeneration in OPTN E50K mice.
Liu X, Hou M, Zhang S, Zhao Y, Wang Q, Jiang M, Du M, Shao Z, Yuan H
Cell death & disease 2021 Jun 15;12(6):613
Cell death & disease 2021 Jun 15;12(6):613
Caloric restriction ameliorates high-fat diet induced cognitive deficits through attenuating neuroinflammation via the TREM2-PI3K/AKT signaling pathway.
Wang R, Zhou Z, Wang D, Zhao Q, Zhang C, Liu C, Zhao H, Yuan C, Yuan D, Wang T
Food & function 2021 Jul 21;12(14):6464-6478
Food & function 2021 Jul 21;12(14):6464-6478
The protective function of taurine on pesticide-induced permanent neurodevelopmental toxicity in juvenile rats.
Liu F, Yuan M, Li C, Guan X, Li B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21273
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21273
Rapid antidepressant-like effect of Fructus Aurantii depends on cAMP-response element binding protein/Brain-derived neurotrophic facto by mediating synaptic transmission.
Wu L, Zhang T, Chen K, Lu C, Liu XF, Zhou JL, Huang YK, Yan H, Chen Y, Zhang CJ, Li JF, Shi SQ, Ren P, Huang X
Phytotherapy research : PTR 2021 Jan;35(1):404-414
Phytotherapy research : PTR 2021 Jan;35(1):404-414
Water treadmill training protects the integrity of the blood-spinal cord barrier following SCI via the BDNF/TrkB-CREB signalling pathway.
Ying X, Xie Q, Yu X, Li S, Wu Q, Chen X, Yue J, Zhou K, Tu W, Jiang S
Neurochemistry international 2021 Feb;143:104945
Neurochemistry international 2021 Feb;143:104945
Meranzin hydrate elicits antidepressant effects and restores reward circuitry.
Liu X, Zhou J, Zhang T, Chen K, Xu M, Wu L, Liu J, Huang Y, Nie B, Shen X, Ren P, Huang X
Behavioural brain research 2021 Feb 1;398:112898
Behavioural brain research 2021 Feb 1;398:112898
Myrtenol improves brain damage and promotes angiogenesis in rats with cerebral infarction by activating the ERK1/2 signalling pathway.
Huang S, Tan Z, Cai J, Wang Z, Tian Y
Pharmaceutical biology 2021 Dec;59(1):584-593
Pharmaceutical biology 2021 Dec;59(1):584-593
Inhibition of P2X4R attenuates white matter injury in mice after intracerebral hemorrhage by regulating microglial phenotypes.
Fu X, Zhou G, Wu X, Xu C, Zhou H, Zhuang J, Peng Y, Cao Y, Zeng H, Li Y, Li J, Gao L, Chen G, Wang L, Yan F
Journal of neuroinflammation 2021 Aug 23;18(1):184
Journal of neuroinflammation 2021 Aug 23;18(1):184
Sodium Butyrate Protects N2a Cells against Aβ Toxicity In Vitro.
Sun J, Yuan B, Wu Y, Gong Y, Guo W, Fu S, Luan Y, Wang W
Mediators of inflammation 2020;2020:7605160
Mediators of inflammation 2020;2020:7605160
Excessive Treadmill Training Enhances Brain-Specific MicroRNA-34a in the Mouse Hippocampus.
Xu L, Zheng YL, Yin X, Xu SJ, Tian D, Zhang CY, Wang S, Ma JZ
Frontiers in molecular neuroscience 2020;13:7
Frontiers in molecular neuroscience 2020;13:7
IRF8 is crucial for the nicotine withdrawal-induced hyperalgesia in mice.
Guo L, Zhang Y, Wang J, Qi Y, Zhang Z
Translational neuroscience 2020;11(1):283-293
Translational neuroscience 2020;11(1):283-293
PKA-Dependent Membrane Surface Recruitment of CI-AMPARs Is Crucial for BCP-Mediated Protection Against Post-acute Ischemic Stroke Cognitive Impairment.
Chen S, Wang Y, Wang X, He M, Zhang L, Dong Z
Frontiers in neurology 2020;11:566067
Frontiers in neurology 2020;11:566067
Chaiyu-Dixian Formula Exerts Protective Effects on Ovarian Follicular Abnormal Development in Chronic Unpredictable Mild Stress (CUMS) Rat Model.
Xu HX, Lin SX, Gong Y, Huo ZX, Zhao CY, Zhu HM, Xi SY
Frontiers in pharmacology 2020;11:245
Frontiers in pharmacology 2020;11:245
DL0410 attenuates oxidative stress and neuroinflammation via BDNF/TrkB/ERK/CREB and Nrf2/HO-1 activation.
Zhang B, Zhao J, Wang Z, Xu L, Liu A, Du G
International immunopharmacology 2020 Sep;86:106729
International immunopharmacology 2020 Sep;86:106729
Anti-Alzheimer's disease activity of secondary metabolites from Xanthoceras sorbifolia Bunge.
Li W, Lu Q, Li X, Liu H, Sun L, Lu X, Zhao Y, Liu P
Food & function 2020 Mar 1;11(3):2067-2079
Food & function 2020 Mar 1;11(3):2067-2079
Rosmarinic acid exerts a neuroprotective effect on spinal cord injury by suppressing oxidative stress and inflammation via modulating the Nrf2/HO-1 and TLR4/NF-κB pathways.
Ma Z, Lu Y, Yang F, Li S, He X, Gao Y, Zhang G, Ren E, Wang Y, Kang X
Toxicology and applied pharmacology 2020 Jun 15;397:115014
Toxicology and applied pharmacology 2020 Jun 15;397:115014
Colocalization of dopamine receptors in BDNF-expressing peptidergic neurons in the paraventricular nucleus of rats.
Zhou L, Zhang Y, Lian H, Li Y, Wang Z
Journal of chemical neuroanatomy 2020 Jul;106:101794
Journal of chemical neuroanatomy 2020 Jul;106:101794
Neuroinflammation induced by secretion of acetylated HMGB1 from activated microglia in hippocampi of mice following chronic cold exposure.
Xu B, Lang LM, Lian S, Guo JR, Wang JF, Liu J, Yang HM, Li SZ
Brain research 2020 Jan 1;1726:146495
Brain research 2020 Jan 1;1726:146495
Curcumin protects rat hippocampal neurons against pseudorabies virus by regulating the BDNF/TrkB pathway.
Yang B, Luo G, Zhang C, Feng L, Luo X, Gan L
Scientific reports 2020 Dec 17;10(1):22204
Scientific reports 2020 Dec 17;10(1):22204
Catalpol Enhances Neurogenesis And Inhibits Apoptosis Of New Neurons Via BDNF, But Not The BDNF/Trkb Pathway.
Zhu HF, Shao Y, Qin L, Wang JH, Feng S, Jiang YB, Wan D
Drug design, development and therapy 2019;13:4145-4157
Drug design, development and therapy 2019;13:4145-4157
RGS4 Regulates Proliferation And Apoptosis Of NSCLC Cells Via microRNA-16 And Brain-Derived Neurotrophic Factor.
He Z, Yu L, Luo S, Li Q, Huang S, An Y
OncoTargets and therapy 2019;12:8701-8714
OncoTargets and therapy 2019;12:8701-8714
Melatonin ameliorates cuprizone-induced reduction of hippocampal neurogenesis, brain-derived neurotrophic factor, and phosphorylation of cyclic AMP response element-binding protein in the mouse dentate gyrus.
Kim W, Hahn KR, Jung HY, Kwon HJ, Nam SM, Kim JW, Park JH, Yoo DY, Kim DW, Won MH, Yoon YS, Hwang IK
Brain and behavior 2019 Sep;9(9):e01388
Brain and behavior 2019 Sep;9(9):e01388
Melatonin alleviates cognition impairment by antagonizing brain insulin resistance in aged rats fed a high-fat diet.
Xu J, Gao H, Zhang L, Rong S, Yang W, Ma C, Chen M, Huang Q, Deng Q, Huang F
Journal of pineal research 2019 Sep;67(2):e12584
Journal of pineal research 2019 Sep;67(2):e12584
Partially Hydrolyzed Guar Gum Attenuates d-Galactose-Induced Oxidative Stress and Restores Gut Microbiota in Rats.
Liu X, Wu C, Han D, Liu J, Liu H, Jiang Z
International journal of molecular sciences 2019 Sep 30;20(19)
International journal of molecular sciences 2019 Sep 30;20(19)
A dual-enzymatically cross-linked injectable gelatin hydrogel loaded with BMSC improves neurological function recovery of traumatic brain injury in rats.
Yao M, Gao F, Xu R, Zhang J, Chen Y, Guan F
Biomaterials science 2019 Sep 24;7(10):4088-4098
Biomaterials science 2019 Sep 24;7(10):4088-4098
Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice.
Buck JM, O'Neill HC, Stitzel JA
Biochemical pharmacology 2019 Oct;168:438-451
Biochemical pharmacology 2019 Oct;168:438-451
Apelin-13 ameliorates chronic water-immersion restraint stress-induced memory performance deficit through upregulation of BDNF in rats.
Shen P, Yue Q, Fu W, Tian SW, You Y
Neuroscience letters 2019 Mar 23;696:151-155
Neuroscience letters 2019 Mar 23;696:151-155
Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats.
Zhou PT, Wang LP, Qu MJ, Shen H, Zheng HR, Deng LD, Ma YY, Wang YY, Wang YT, Tang YH, Tian HL, Zhang ZJ, Yang GY
CNS neuroscience & therapeutics 2019 Jun;25(6):748-758
CNS neuroscience & therapeutics 2019 Jun;25(6):748-758
Improvement of motor function induced by skeletal muscle contraction in spinal cord-injured rats.
Hayashi N, Himi N, Nakamura-Maruyama E, Okabe N, Sakamoto I, Hasegawa T, Miyamoto O
The spine journal : official journal of the North American Spine Society 2019 Jun;19(6):1094-1105
The spine journal : official journal of the North American Spine Society 2019 Jun;19(6):1094-1105
Improvement in neurogenesis and memory function by administration of Passiflora incarnata L. extract applied to sleep disorder in rodent models.
Kim GH, Lim K, Yang HS, Lee JK, Kim Y, Park SK, Kim SH, Park S, Kim TH, Moon JS, Hwang IK, Yoon YS, Seo HS, Nam SM, Kim MY, Yoon SG, Seong JK, Yi SS
Journal of chemical neuroanatomy 2019 Jul;98:27-40
Journal of chemical neuroanatomy 2019 Jul;98:27-40
Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats.
Ying X, Tu W, Li S, Wu Q, Chen X, Zhou Y, Hu J, Yang G, Jiang S
Life sciences 2019 Jul 15;229:187-199
Life sciences 2019 Jul 15;229:187-199
Protective effects of astaxanthin on subarachnoid hemorrhage-induced early brain injury: Reduction of cerebral vasospasm and improvement of neuron survival and mitochondrial function.
Wang Y, Liu Y, Li Y, Liu B, Wu P, Xu S, Shi H
Acta histochemica 2019 Jan;121(1):56-63
Acta histochemica 2019 Jan;121(1):56-63
Proteomic profiling of the neurons in mice with depressive-like behavior induced by corticosterone and the regulation of berberine: pivotal sites of oxidative phosphorylation.
Gong Q, Yan XJ, Lei F, Wang ML, He LL, Luo YY, Gao HW, Feng YL, Yang SL, Li J, Du LJ
Molecular brain 2019 Dec 30;12(1):118
Molecular brain 2019 Dec 30;12(1):118
Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure.
Xu B, Lang LM, Li SZ, Guo JR, Wang JF, Yang HM, Lian S
Biomolecules 2019 Aug 30;9(9)
Biomolecules 2019 Aug 30;9(9)
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
Rusmini P, Cortese K, Crippa V, Cristofani R, Cicardi ME, Ferrari V, Vezzoli G, Tedesco B, Meroni M, Messi E, Piccolella M, Galbiati M, Garrè M, Morelli E, Vaccari T, Poletti A
Autophagy 2019 Apr;15(4):631-651
Autophagy 2019 Apr;15(4):631-651
The Anticonvulsant Effects of Baldrinal on Pilocarpine-Induced convulsion in Adult Male Mice.
Zhang X, Li X, Liu N, Zheng P, Ma L, Guo F, Sun T, Zhou R, Yu J
Molecules (Basel, Switzerland) 2019 Apr 24;24(8)
Molecules (Basel, Switzerland) 2019 Apr 24;24(8)
Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions.
Dai TT, Wang B, Xiao ZY, You Y, Tian SW
Neuroscience 2018 Oct 15;390:151-159
Neuroscience 2018 Oct 15;390:151-159
Bacopa monnieri extract improves novel object recognition, cell proliferation, neuroblast differentiation, brain-derived neurotrophic factor, and phosphorylation of cAMP response element-binding protein in the dentate gyrus.
Kwon HJ, Jung HY, Hahn KR, Kim W, Kim JW, Yoo DY, Yoon YS, Hwang IK, Kim DW
Laboratory animal research 2018 Dec;34(4):239-247
Laboratory animal research 2018 Dec;34(4):239-247
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