BS2927

antibody from Bioworld Technology, Inc
Targeting: GCLM GLCLR
Provider product page for BS2927
Western blot
Immunohistochemistry

Antibody data

Product number
BS2927 - Provider product page
Provider
Bioworld Technology, Inc
Product name
GCSm ÎÛ (V91) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 50-100 of Human GCSm-ÎÛ.
Description
Gamma-glutamylcysteine synthetase (ÎÛ-GCS) is the rate limiting enzyme for glutathione (L-ÎÛ-glutamyl-L-cysteinylglycine, GSH) synthesis. GSH is ubiquitous in mammalian cells as a vital intra- and extracellular protective antioxidant. ÎÛ-GCS is a heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic ntioxidants, heat shock, oxidants and cytokines. The human ÎÛ-GCS gene encoding the 367 amino acid catalytic subunit maps to chromosome 6p12. The human ÎÛ-GCS gene encoding the regulatory subunit maps to chromosome 1p22-p21. The two subunits of ÎÛ-GCS form a heterodimeric zinc metalloprotein that gains activity through formation of a reversible disulfide bond.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GCLM protein structure - BS2927 shown in red.