Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- GTX16315 - Provider product page
- Provider
- GeneTex
- Product name
- GCLC antibody, N-term
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse
- Host
- Rabbit
Submitted references Trans-cinnamic acid attenuates UVA-induced photoaging through inhibition of AP-1 activation and induction of Nrf2-mediated antioxidant genes in human skin fibroblasts.
Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway.
Hericium erinaceus Inhibits TNF-α-Induced Angiogenesis and ROS Generation through Suppression of MMP-9/NF-κB Signaling and Activation of Nrf2-Mediated Antioxidant Genes in Human EA.hy926 Endothelial Cells.
Caveolin-1 Expression Ameliorates Nephrotic Damage in a Rabbit Model of Cholesterol-Induced Hypercholesterolemia.
Dermato-protective properties of ergothioneine through induction of Nrf2/ARE-mediated antioxidant genes in UVA-irradiated Human keratinocytes.
M1 Muscarinic Receptor Deficiency Attenuates Azoxymethane-Induced Chronic Liver Injury in Mice.
Anti-angiogenic properties of coenzyme Q0 through downregulation of MMP-9/NF-κB and upregulation of HO-1 signaling in TNF-α-activated human endothelial cells.
M1 muscarinic receptors modify oxidative stress response to acetaminophen-induced acute liver injury.
Hseu YC, Korivi M, Lin FY, Li ML, Lin RW, Wu JJ, Yang HL
Journal of dermatological science 2018 May;90(2):123-134
Journal of dermatological science 2018 May;90(2):123-134
Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway.
Wu YL, Chang JC, Lin WY, Li CC, Hsieh M, Chen HW, Wang TS, Wu WT, Liu CS, Liu KL
Free radical biology & medicine 2018 Feb 1;115:309-317
Free radical biology & medicine 2018 Feb 1;115:309-317
Hericium erinaceus Inhibits TNF-α-Induced Angiogenesis and ROS Generation through Suppression of MMP-9/NF-κB Signaling and Activation of Nrf2-Mediated Antioxidant Genes in Human EA.hy926 Endothelial Cells.
Chang HC, Yang HL, Pan JH, Korivi M, Pan JY, Hsieh MC, Chao PM, Huang PJ, Tsai CT, Hseu YC
Oxidative medicine and cellular longevity 2016;2016:8257238
Oxidative medicine and cellular longevity 2016;2016:8257238
Caveolin-1 Expression Ameliorates Nephrotic Damage in a Rabbit Model of Cholesterol-Induced Hypercholesterolemia.
Chen YH, Lin WW, Liu CS, Hsu LS, Lin YM, Su SL
PloS one 2016;11(4):e0154210
PloS one 2016;11(4):e0154210
Dermato-protective properties of ergothioneine through induction of Nrf2/ARE-mediated antioxidant genes in UVA-irradiated Human keratinocytes.
Hseu YC, Lo HW, Korivi M, Tsai YC, Tang MJ, Yang HL
Free radical biology & medicine 2015 Sep;86:102-17
Free radical biology & medicine 2015 Sep;86:102-17
M1 Muscarinic Receptor Deficiency Attenuates Azoxymethane-Induced Chronic Liver Injury in Mice.
Rachakonda V, Jadeja RN, Urrunaga NH, Shah N, Ahmad D, Cheng K, Twaddell WS, Raufman JP, Khurana S
Scientific reports 2015 Sep 16;5:14110
Scientific reports 2015 Sep 16;5:14110
Anti-angiogenic properties of coenzyme Q0 through downregulation of MMP-9/NF-κB and upregulation of HO-1 signaling in TNF-α-activated human endothelial cells.
Yang HL, Korivi M, Lin MW, Chen SC, Chou CW, Hseu YC
Biochemical pharmacology 2015 Nov 1;98(1):144-56
Biochemical pharmacology 2015 Nov 1;98(1):144-56
M1 muscarinic receptors modify oxidative stress response to acetaminophen-induced acute liver injury.
Urrunaga NH, Jadeja RN, Rachakonda V, Ahmad D, McLean LP, Cheng K, Shah V, Twaddell WS, Raufman JP, Khurana S
Free radical biology & medicine 2015 Jan;78:66-81
Free radical biology & medicine 2015 Jan;78:66-81
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- WB analysis of human liver lysate using GCLC antibody.
- Validation comment
- WB
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Human liver lysates were used for Western Blot analysis. The membrane was blotted with anti-GCLC Antibody Titration: 0.2-1 ug/ml. A: - blocking peptide. B: + blocking peptide.
- Validation comment
- WB